CDP-paratose 2-epimerase
Details
- Name
- CDP-paratose 2-epimerase
- Synonyms
- 5.1.3.10
- CDP-tyvelose 2-epimerase
- Gene Name
- rfbE
- Organism
- Salmonella typhi
- Amino acid sequence
>lcl|BSEQ0020543|CDP-paratose 2-epimerase MKLLITGGCGFLGSNLASFALSQGIDLIVFDNLSRKGATDNLHWLSSLGNFEFVHGDIRN KNDVTRLITKYMPDSCFHLAGQVAMTTSIDNPCMDFEINVGGTLNLLEAVRQYNSNCNII YSSTNKVYGDLEQYKYNETETRYTCVDKPNGYDESTQLDFHSPYGCSKGAADQYMLDYAR IFGLNTVVFRHSSMYGGRQFATYDQGWVGWFCQKAVEIKNGINKPFTISGNGKQVRDVLH AEDMISLYFTALANVSKIRGNAFNIGGTIVNSLSLLELFKLLEDYCNIDMRFTNLPVRES DQRVFVADIKKITNAIDWSPKVSAKDGVQKMYDWTSSI
- Number of residues
- 338
- Molecular Weight
- 37957.675
- Theoretical pI
- 6.25
- GO Classification
- FunctionsCDP-abequose epimerase activityProcesseslipopolysaccharide biosynthetic process
- General Function
- Cdp-abequose epimerase activity
- Specific Function
- Catalyzes the isomeration of CDP-paratose to CDP-tyvelose.
- Pfam Domain Function
- GDP_Man_Dehyd (PF16363)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0020544|CDP-paratose 2-epimerase (rfbE) ATGAAGCTTTTAATTACCGGTGGATGTGGCTTCCTTGGGAGTAATCTTGCCTCCTTTGCT TTAAGTCAAGGGATTGATTTAATTGTATTCGATAATCTATCACGTAAAGGTGCAACAGAT AATTTACATTGGTTATCCTCCTTAGGAAACTTTGAGTTTGTACATGGTGATATTCGCAAC AAAAATGATGTTACAAGATTAATAACTAAGTATATGCCTGATAGCTGTTTTCATCTTGCA GGTCAAGTGGCAATGACTACATCTATTGACAATCCTTGTATGGATTTTGAAATTAATGTA GGTGGAACTTTAAATTTACTTGAGGCAGTACGGCAGTATAATTCAAATTGTAATATAATT TATTCATCAACAAATAAAGTATACGGCGATCTTGAGCAATATAAATACAATGAAACAGAA ACTAGATACACTTGTGTAGATAAGCCTAATGGATATGATGAGAGCACACAATTAGATTTC CACTCACCATATGGTTGTTCAAAAGGTGCTGCAGACCAATACATGCTTGATTATGCAAGG ATTTTTGGTTTGAATACAGTGGTGTTCAGGCATTCATCAATGTATGGTGGGAGACAGTTT GCTACTTATGATCAAGGCTGGGTAGGTTGGTTTTGTCAAAAAGCGGTTGAAATTAAAAAT GGTATTAATAAACCCTTCACTATTTCTGGTAATGGTAAGCAAGTTAGGGATGTTTTGCAT GCTGAAGATATGATTTCGTTATATTTCACTGCCTTGGCAAATGTATCAAAAATTAGGGGG AACGCTTTTAATATTGGTGGTACCATTGTCAACAGCCTATCATTACTTGAATTATTCAAA TTGCTTGAAGATTATTGCAACATAGATATGAGGTTCACTAATTTACCTGTAAGGGAAAGT GATCAGCGTGTTTTTGTTGCAGATATTAAAAAAATCACTAATGCAATTGACTGGAGCCCG AAAGTCTCGGCAAAAGATGGTGTCCAGAAAATGTATGATTGGACTAGTTCTATATGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P14169 UniProtKB Entry Name RFBE_SALTI GenBank Protein ID 154340 GenBank Gene ID M29682 - General References
- Verma N, Reeves P: Identification and sequence of rfbS and rfbE, which determine antigenic specificity of group A and group D salmonellae. J Bacteriol. 1989 Oct;171(10):5694-701. [Article]
- Parkhill J, Dougan G, James KD, Thomson NR, Pickard D, Wain J, Churcher C, Mungall KL, Bentley SD, Holden MT, Sebaihia M, Baker S, Basham D, Brooks K, Chillingworth T, Connerton P, Cronin A, Davis P, Davies RM, Dowd L, White N, Farrar J, Feltwell T, Hamlin N, Haque A, Hien TT, Holroyd S, Jagels K, Krogh A, Larsen TS, Leather S, Moule S, O'Gaora P, Parry C, Quail M, Rutherford K, Simmonds M, Skelton J, Stevens K, Whitehead S, Barrell BG: Complete genome sequence of a multiple drug resistant Salmonella enterica serovar Typhi CT18. Nature. 2001 Oct 25;413(6858):848-52. [Article]
- Deng W, Liou SR, Plunkett G 3rd, Mayhew GF, Rose DJ, Burland V, Kodoyianni V, Schwartz DC, Blattner FR: Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and CT18. J Bacteriol. 2003 Apr;185(7):2330-7. [Article]
- Koropatkin NM, Liu HW, Holden HM: High resolution x-ray structure of tyvelose epimerase from Salmonella typhi. J Biol Chem. 2003 Jun 6;278(23):20874-81. Epub 2003 Mar 17. [Article]