Cytochrome c oxidase subunit 6B1

Details

Name
Cytochrome c oxidase subunit 6B1
Synonyms
  • COX VIb-1
  • COX6B
  • Cytochrome c oxidase subunit VIb isoform 1
Gene Name
COX6B1
Organism
Humans
Amino acid sequence
>lcl|BSEQ0017292|Cytochrome c oxidase subunit 6B1
MAEDMETKIKNYKTAPFDSRFPNQNQTRNCWQNYLDFHRCQKAMTAKGGDISVCEWYQRV
YQSLCPTSWVTDWDEQRAEGTFPGKI
Number of residues
86
Molecular Weight
10192.345
Theoretical pI
7.13
GO Classification
Functions
cytochrome-c oxidase activity
Processes
cellular metabolic process / gene expression / hydrogen ion transmembrane transport / respiratory electron transport chain / small molecule metabolic process / substantia nigra development / transcription initiation from RNA polymerase II promoter
Components
mitochondrial inner membrane / mitochondrial intermembrane space / mitochondrion
General Function
Cytochrome-c oxidase activity
Specific Function
Connects the two COX monomers into the physiological dimeric form.
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Mitochondrion intermembrane space
Gene sequence
>lcl|BSEQ0017293|Cytochrome c oxidase subunit 6B1 (COX6B1)
ATGGCGGAAGACATGGAGACCAAAATCAAGAACTACAAGACCGCCCCTTTTGACAGCCGC
TTCCCCAACCAGAACCAGACTAGAAACTGCTGGCAGAACTACCTGGACTTCCACCGCTGT
CAGAAGGCAATGACCGCTAAAGGAGGCGATATCTCTGTGTGCGAATGGTACCAGCGTGTG
TACCAGTCCCTCTGCCCCACATCCTGGGTCACAGACTGGGATGAGCAACGGGCTGAAGGC
ACGTTTCCCGGGAAGATCTGA
Chromosome Location
19
Locus
19q13.1
External Identifiers
ResourceLink
UniProtKB IDP14854
UniProtKB Entry NameCX6B1_HUMAN
GenBank Protein ID30295
GenBank Gene IDX13923
HGNC IDHGNC:2280
General References
  1. Taanman JW, Schrage C, Ponne N, Bolhuis P, de Vries H, Agsteribbe E: Nucleotide sequence of cDNA encoding subunit VIb of human cytochrome c oxidase. Nucleic Acids Res. 1989 Feb 25;17(4):1766. [Article]
  2. Taanman JW, Schrage C, Ponne NJ, Das AT, Bolhuis PA, de Vries H, Agsteribbe E: Isolation of cDNAs encoding subunit VIb of cytochrome c oxidase and steady-state levels of coxVIb mRNA in different tissues. Gene. 1990 Sep 14;93(2):285-91. [Article]
  3. Carrero-Valenzuela RD, Quan F, Lightowlers R, Kennaway NG, Litt M, Forte M: Human cytochrome c oxidase subunit VIb: characterization and mapping of a multigene family. Gene. 1991 Jun 30;102(2):229-36. [Article]
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  7. Taanman JW, Schrage C, Bokma E, Reuvekamp P, Agsteribbe E, De Vries H: Nucleotide sequence of the last exon of the gene for human cytochrome c oxidase subunit VIb and its flanking regions. Biochim Biophys Acta. 1991 Jun 13;1089(2):283-5. [Article]
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Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB02659Cholic AcidapprovedunknownDetails
DB04464N-FormylmethionineexperimentalunknownDetails