Alkaline protease
Details
- Name
- Alkaline protease
- Synonyms
- 3.4.21.-
- Gene Name
- Not Available
- Organism
- Bacillus alcalophilus
- Amino acid sequence
>lcl|BSEQ0016422|Alkaline protease MKKPLGKIVASTALLISVAFSSSIASAAEEAKEKYLIGFNEQEAVSEFVEQVEANDEVAI LSEEEEVEIELLHEFETIPVLSVELSPEDVDALELDPAISYIEEDAEVTTMAQSVPWGIS RVQAPAAHNRGLTGSGVKVAVLDTGISTHPDLNIRGGASFVPGEPSTQDGNGHGTHVAGT IAALNNSIGVLGVAPNAELYAVKVLGASGSGSVSSIAQGLEWAGNNGMHVANLSLGSPSP SATLEQAVNSATSRGVLVVAASGNSGAGSISYPARYANAMAVGATDQNNNRASFSQYGAG LDIVAPGVNVQSTYPGSTYASLNGTSMATPHVAGAAALVKQKNPSWSNVQIRNHLKNTAT SLGSTNLYGSGLVNAEAATR
- Number of residues
- 380
- Molecular Weight
- 38852.735
- Theoretical pI
- 4.39
- GO Classification
- Functionsmetal ion binding / serine-type endopeptidase activityComponentsextracellular region
- General Function
- Serine-type endopeptidase activity
- Specific Function
- Not Available
- Pfam Domain Function
- Peptidase_S8 (PF00082)
- Transmembrane Regions
- Not Available
- Cellular Location
- Secreted
- Gene sequence
>lcl|BSEQ0002814|1143 bp ATGAAGAAACCGTTGGGGAAAATTGTCGCAAGCACCGCACTACTCATTTCTGTTGCTTTT AGTTCATCGATCGCATCGGCTGCTGAAGAAGCAAAAGAAAAATATTTAATTGGCTTTAAT GAGCAGGAAGCTGTCAGTGAGTTTGTAGAACAAGTAGAGGCAAATGACGAGGTCGCCATT CTCTCTGAGGAAGAGGAAGTCGAAATTGAATTGCTTCATGAATTTGAAACGATTCCTGTT TTATCCGTTGAGTTAAGCCCAGAAGATGTGGACGCGCTTGAACTCGATCCAGCGATTTCT TATATTGAAGAGGATGCAGAAGTAACGACAATGGCGCAATCAGTGCCATGGGGAATTAGC CGTGTGCAAGCCCCAGCTGCCCATAACCGTGGATTGACAGGTTCTGGTGTAAAAGTTGCT GTCCTCGATACAGGTATTTCCACTCATCCAGACTTAAATATTCGTGGTGGCGCTAGCTTT GTACCAGGGGAACCATCCACTCAAGATGGGAATGGGCATGGCACGCATGTGGCTGGGACG ATTGCTGCTTTAAACAATTCGATTGGCGTTCTTGGCGTAGCACCGAACGCGGAACTATAC GCTGTTAAAGTATTAGGGGCGAGCGGTTCAGGTTCGGTCAGCTCGATTGCCCAAGGATTG GAATGGGCAGGGAACAATGGCATGCACGTTGCTAATTTGAGTTTAGGAAGCCCTTCGCCA AGTGCCACACTTGAGCAAGCTGTTAATAGCGCGACTTCTAGAGGCGTTCTTGTTGTAGCG GCATCTGGGAATTCAGGTGCAGGCTCAATCAGCTATCCGGCCCGTTATGCGAACGCAATG GCAGTCGGAGCTACTGACCAAAACAACAACCGCGCCAGCTTTTCACAGTATGGCGCAGGG CTTGACATTGTCGCACCAGGTGTAAACGTGCAGAGCACATACCCAGGTTCAACGTATGCC AGCTTAAACGGTACATCGATGGCTACTCCTCATGTTGCAGGTGCAGCAGCCCTTGTTAAA CAAAAGAACCCATCTTGGTCCAATGTACAAATCCGCAATCATCTAAAGAATACGGCAACG AGCTTAGGAAGCACGAACTTGTATGGAAGCGGACTTGTCAATGCAGAAGCGGCAACACGC TAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P27693 UniProtKB Entry Name ELYA_BACAO GenBank Protein ID 142457 GenBank Gene ID M65086 - General References
- van der Laan JC, Gerritse G, Mulleners LJ, van der Hoek RA, Quax WJ: Cloning, characterization, and multiple chromosomal integration of a Bacillus alkaline protease gene. Appl Environ Microbiol. 1991 Apr;57(4):901-9. [Article]
- van der Laan JM, Teplyakov AV, Kelders H, Kalk KH, Misset O, Mulleners LJ, Dijkstra BW: Crystal structure of the high-alkaline serine protease PB92 from Bacillus alcalophilus. Protein Eng. 1992 Jul;5(5):405-11. [Article]
- Sobek H, Hecht HJ, Aehle W, Schomburg D: X-ray structure determination and comparison of two crystal forms of a variant (Asn115Arg) of the alkaline protease from Bacillus alcalophilus refined at 1.85 A resolution. J Mol Biol. 1992 Nov 5;228(1):108-17. [Article]
- Martin JR, Mulder FA, Karimi-Nejad Y, van der Zwan J, Mariani M, Schipper D, Boelens R: The solution structure of serine protease PB92 from Bacillus alcalophilus presents a rigid fold with a flexible substrate-binding site. Structure. 1997 Apr 15;5(4):521-32. [Article]