Sodium- and chloride-dependent taurine transporter
Details
- Name
- Sodium- and chloride-dependent taurine transporter
- Synonyms
- Solute carrier family 6 member 6
- Gene Name
- SLC6A6
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0051326|Sodium- and chloride-dependent taurine transporter MATKEKLQCLKDFHKDILKPSPGKSPGTRPEDEAEGKPPQREKWSSKIDFVLSVAGGFVG LGNVWRFPYLCYKNGGGAFLIPYFIFLFGSGLPVFFLEIIIGQYTSEGGITCWEKICPLF SGIGYASVVIVSLLNVYYIVILAWATYYLFQSFQKELPWAHCNHSWNTPHCMEDTMRKNK SVWITISSTNFTSPVIEFWERNVLSLSPGIDHPGSLKWDLALCLLLVWLVCFFCIWKGVR STGKVVYFTATFPFAMLLVLLVRGLTLPGAGAGIKFYLYPDITRLEDPQVWIDAGTQIFF SYAICLGAMTSLGSYNKYKYNSYRDCMLLGCLNSGTSFVSGFAIFSILGFMAQEQGVDIA DVAESGPGLAFIAYPKAVTMMPLPTFWSILFFIMLLLLGLDSQFVEVEGQITSLVDLYPS FLRKGYRREIFIAFVCSISYLLGLTMVTEGGMYVFQLFDYYAASGVCLLWVAFFECFVIA WIYGGDNLYDGIEDMIGYRPGPWMKYSWAVITPVLCVGCFIFSLVKYVPLTYNKTYVYPN WAIGLGWSLALSSMLCVPLVIVIRLCQTEGPFLVRVKYLLTPREPNRWAVEREGATPYNS RTVMNGALVKPTHIIVETMM
- Number of residues
- 620
- Molecular Weight
- 69829.405
- Theoretical pI
- Not Available
- GO Classification
- Functionsamino acid transmembrane transporter activity / neurotransmitter / taurineProcessesamino acid transmembrane transport / amino acid transport / cellular amino acid metabolic process / taurine transport / transportComponentsintegral component of membrane / integral component of plasma membrane / plasma membrane
- General Function
- Sodium-dependent taurine and beta-alanine transporter. Chloride ions are necessary for optimal uptake.
- Specific Function
- Amino acid transmembrane transporter activity
- Pfam Domain Function
- SNF (PF00209)
- Transmembrane Regions
- 50-70 78-97 122-142 218-236 245-262 298-315 327-348 381-400 430-448 465-485 506-525 545-563
- Cellular Location
- Cell membrane
- Gene sequence
>lcl|BSEQ0051327|Sodium- and chloride-dependent taurine transporter (SLC6A6) ATGGCCACCAAGGAGAAGCTGCAGTGTCTGAAAGATTTCCACAAGGACATCCTGAAGCCC TCACCAGGGAAGAGCCCAGGCACGCGGCCTGAGGACGAGGCTGAGGGAAAACCTCCGCAG AGGGAGAAGTGGTCTAGCAAGATCGACTTTGTGCTCTCTGTGGCTGGCGGCTTCGTGGGC TTGGGCAACGTCTGGCGCTTCCCGTACCTCTGCTACAAGAATGGTGGAGGTGCGTTTCTC ATACCGTATTTTATTTTCCTGTTTGGGAGCGGCCTGCCTGTGTTTTTCTTGGAGATCATC ATAGGCCAGTACACCTCTGAAGGGGGCATCACCTGCTGGGAAAAGATCTGCCCCTTGTTC TCTGGTATCGGCTATGCCTCCGTTGTAATTGTGTCCCTCCTGAATGTCTACTACATCGTC ATCCTGGCCTGGGCCACATACTACCTGTTCCAGTCCTTCCAGAAGGAGCTGCCCTGGGCA CACTGCAACCACAGCTGGAACACACCTCACTGCATGGAGGACACCATGCGCAAGAACAAG AGTGTCTGGATCACCATCAGCTCCACCAACTTCACCTCCCCTGTCATCGAGTTCTGGGAG CGCAACGTGCTGAGCTTGTCCCCTGGAATCGACCACCCAGGCTCTCTGAAATGGGACCTC GCTCTCTGCCTTCTTTTAGTCTGGCTAGTGTGTTTCTTCTGCATCTGGAAGGGCGTCAGG TCCACTGGGAAGGTCGTCTACTTCACAGCCACTTTTCCATTCGCCATGCTCCTGGTGCTG CTGGTCCGAGGGCTGACGCTGCCGGGCGCGGGCGCAGGCATCAAGTTCTATCTGTATCCT GACATCACCCGCCTTGAGGACCCACAGGTGTGGATTGACGCTGGGACTCAGATATTCTTC TCTTATGCCATCTGCCTGGGGGCTATGACCTCGCTGGGGAGCTACAACAAGTACAAGTAT AACTCGTACAGGGACTGTATGCTGCTGGGATGCCTGAACAGTGGTACCAGTTTTGTGTCT GGCTTCGCAATTTTTTCCATCCTGGGCTTCATGGCACAAGAGCAAGGGGTGGACATTGCT GATGTGGCTGAGTCAGGTCCTGGCCTGGCCTTCATTGCCTACCCAAAAGCTGTGACAATG ATGCCGCTGCCCACATTTTGGTCCATTCTTTTTTTTATTATGCTTCTCTTGCTTGGACTG GATAGCCAGTTTGTTGAAGTTGAAGGACAGATCACATCCTTGGTTGATCTTTACCCATCC TTCCTAAGGAAGGGTTATCGTCGGGAAATCTTCATCGCCTTCGTGTGTAGCATCAGCTAC CTGCTGGGGCTGACGATGGTGACGGAGGGTGGCATGTATGTGTTTCAGCTCTTTGACTAC TATGCAGCTAGCGGTGTATGCCTTTTGTGGGTTGCATTCTTTGAATGTTTTGTTATTGCC TGGATATATGGAGGTGATAACCTTTATGATGGTATTGAGGACATGATTGGCTATCGGCCC GGGCCCTGGATGAAGTACAGCTGGGCTGTGATCACTCCAGTTCTCTGTGTTGGATGTTTC ATCTTCTCGCTCGTCAAGTACGTACCCCTGACCTACAACAAAACATACGTGTACCCCAAC TGGGCCATTGGGCTGGGCTGGAGCCTGGCCCTTTCCTCCATGCTCTGCGTTCCCTTGGTC ATCGTCATCCGCCTCTGCCAGACTGAGGGGCCGTTCCTTGTGAGAGTCAAGTACCTGCTG ACCCCAAGGGAACCCAACCGCTGGGCTGTGGAGCGCGAGGGAGCCACACCTTACAACTCT CGCACCGTCATGAACGGCGCTCTCGTGAAACCGACCCACATCATTGTGGAGACCATGATG TGA
- Chromosome Location
- 3
- Locus
- 3p25.1
- External Identifiers
Resource Link UniProtKB ID P31641 UniProtKB Entry Name SC6A6_HUMAN HGNC ID HGNC:11052 - General References
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