Orange carotenoid-binding protein

Details

Name
Orange carotenoid-binding protein
Synonyms
  • OCP
Gene Name
Not Available
Organism
Arthrospira maxima
Amino acid sequence
>lcl|BSEQ0011995|Orange carotenoid-binding protein
MPFTIDTARSIFPETLAADVVPATIARFKQLSAEDQLALIWFAYLEMGKTITIAAPGAAN
MQFAENTLQEIRQMTPLQQTQAMCDLANRTDTPICRTYASWSPNIKLGFWYELGRFMDQG
LVAPIPEGYKLSANANAILVTIQGIDPGQQITVLRNCVVDMGFDTSKLGSYQRVAEPVVP
PQEMSQRTKVQIEGVTNSTVLQYMDNLNANDFDNLISLFAEDGALQPPFQKPIVGKENTL
RFFREECQNLKLIPERGVSEPTEDGYTQIKVTGKVQTPWFGGNVGMNIAWRFLLNPENKV
FFVAIDLLASPKELLNL
Number of residues
317
Molecular Weight
35347.29
Theoretical pI
4.54
GO Classification
Functions
chloride ion binding / photoreceptor activity
Processes
light absorption / protein-chromophore linkage / transport
Components
phycobilisome
General Function
Photoreceptor activity
Specific Function
Acts as a blue-light photoreceptor and photo-protectant. Essential for inhibiting damaged induced by excess blue-green light via a process known as non-photochemical quenching (NPQ). Binding carotenoids improves OCP's intrinsic photoprotectant activity by broadening its absorption spectrum and facilitating the dissipation of absorbed energy (PubMed:15751975). In the dark or dim light the stable inactive form (OCP-O) is orange, upon illumination with blue-green light it converts to a metastable active red form (OCP-R), inducing energy dissipation, quenching cellular fluorescence via NPQ (By similarity).
Pfam Domain Function
Transmembrane Regions
Not Available
Cellular Location
Cellular thylakoid membrane
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDP83689
UniProtKB Entry NameOCP_ARTMA
General References
  1. Wu YP, Krogmann DW: The orange carotenoid protein of Synechocystis PCC 6803. Biochim Biophys Acta. 1997 Nov 10;1322(1):1-7. [Article]
  2. Kerfeld CA: Water-soluble carotenoid proteins of cyanobacteria. Arch Biochem Biophys. 2004 Oct 1;430(1):2-9. [Article]
  3. Polivka T, Kerfeld CA, Pascher T, Sundstrom V: Spectroscopic properties of the carotenoid 3'-hydroxyechinenone in the orange carotenoid protein from the cyanobacterium Arthrospira maxima. Biochemistry. 2005 Mar 15;44(10):3994-4003. [Article]
  4. Kerfeld CA, Wu YP, Chan C, Krogmann DW, Yeates TO: Crystals of the carotenoid protein from Arthrospira maxima containing uniformly oriented pigment molecules. Acta Crystallogr D Biol Crystallogr. 1997 Nov 1;53(Pt 6):720-3. [Article]
  5. Kerfeld CA, Sawaya MR, Brahmandam V, Cascio D, Ho KK, Trevithick-Sutton CC, Krogmann DW, Yeates TO: The crystal structure of a cyanobacterial water-soluble carotenoid binding protein. Structure. 2003 Jan;11(1):55-65. [Article]

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB02772Sucroseapproved, experimental, investigationalunknownDetails