Prostaglandin D2 receptor
Details
- Name
- Prostaglandin D2 receptor
- Synonyms
- PGD receptor
- Prostanoid DP receptor
- Gene Name
- PTGDR
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0000589|Prostaglandin D2 receptor MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSV FYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSST LQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPG TWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCT RDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTS EEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
- Number of residues
- 359
- Molecular Weight
- 40270.11
- Theoretical pI
- 9.32
- GO Classification
- Functionsprostaglandin D receptor activity / prostaglandin J receptor activityProcessesadenosine metabolic process / cellular response to prostaglandin D stimulus / G-protein coupled receptor signaling pathway / inflammatory response / male sex determination / sleepComponentsintegral component of membrane / plasma membrane
- General Function
- Prostaglandin j receptor activity
- Specific Function
- Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate (By similarity).
- Pfam Domain Function
- 7tm_1 (PF00001)
- Transmembrane Regions
- 22-42 60-80 108-128 151-171 196-216 263-283 311-331
- Cellular Location
- Cell membrane
- Gene sequence
>lcl|BSEQ0010238|Prostaglandin D2 receptor (PTGDR) ATGAAGTCGCCGTTCTACCGCTGCCAGAACACCACCTCTGTGGAAAAAGGCAACTCGGCG GTGATGGGCGGGGTGCTCTTCAGCACCGGCCTCCTGGGCAACCTGCTGGCCCTGGGGCTG CTGGCGCGCTCGGGGCTGGGGTGGTGCTCGCGGCGTCCACTGCGCCCGCTGCCCTCGGTC TTCTACATGCTGGTGTGTGGCCTGACGGTCACCGACTTGCTGGGCAAGTGCCTCCTAAGC CCGGTGGTGCTGGCTGCCTACGCTCAGAACCGGAGTCTGCGGGTGCTTGCGCCCGCATTG GACAACTCGTTGTGCCAAGCCTTCGCCTTCTTCATGTCCTTCTTTGGGCTCTCCTCGACA CTGCAACTCCTGGCCATGGCACTGGAGTGCTGGCTCTCCCTAGGGCACCCTTTCTTCTAC CGACGGCACATCACCCTGCGCCTGGGCGCACTGGTGGCCCCGGTGGTGAGCGCCTTCTCC CTGGCTTTCTGCGCGCTACCTTTCATGGGCTTCGGGAAGTTCGTGCAGTACTGCCCCGGC ACCTGGTGCTTTATCCAGATGGTCCACGAGGAGGGCTCGCTGTCGGTGCTGGGGTACTCT GTGCTCTACTCCAGCCTCATGGCGCTGCTGGTCCTCGCCACCGTGCTGTGCAACCTCGGC GCCATGCGCAACCTCTATGCGATGCACCGGCGGCTGCAGCGGCACCCGCGCTCCTGCACC AGGGACTGTGCCGAGCCGCGCGCGGACGGGAGGGAAGCGTCCCCTCAGCCCCTGGAGGAG CTGGATCACCTCCTGCTGCTGGCGCTGATGACCGTGCTCTTCACTATGTGTTCTCTGCCC GTAATTTATCGCGCTTACTATGGAGCATTTAAGGATGTCAAGGAGAAAAACAGGACCTCT GAAGAAGCAGAAGACCTCCGAGCCTTGCGATTTCTATCTGTGATTTCAATTGTGGACCCT TGGATTTTTATCATTTTCAGATCTCCAGTATTTCGGATATTTTTTCACAAGATTTTCATT AGACCTCTTAGGTACAGGAGCCGGTGCAGCAATTCCACTAACATGGAATCCAGTCTGTGA
- Chromosome Location
- 14
- Locus
- 14q22.1
- External Identifiers
Resource Link UniProtKB ID Q13258 UniProtKB Entry Name PD2R_HUMAN GenBank Protein ID 940379 GenBank Gene ID U31332 GenAtlas ID PTGDR HGNC ID HGNC:9591 - General References
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