Glutamate-gated chloride channel

Details

Name
Glutamate-gated chloride channel
Synonyms
Not Available
Gene Name
GluClX
Organism
Onchocerca volvulus
Amino acid sequence
>lcl|BSEQ0051977|Glutamate-gated chloride channel
MNSFPIVCWNLAFLILVVAKKKLKEQEIIQRTLKDYDWRVRPRGNNLSWPDTGGPVLVSV
NIYLRSISKIDDVNMEYSAQFTFREEWNDARLGYERLADENTQVPPFVVLAASEQPDLTQ
QIWMPDTFFQNEKEARRHLIDKPNVLIRIHPDGQILYSVRLSLVLSCPMSLEYYPLDRQT
CLIDLASYAYTTDDIKYEWKVKNPIQQKEGLRQSLPSFELQDVLTEYCTSKTNTGEYSCA
RVLLLLRREYRFSYYLIQLYIPCIMLVVVSWVSFWLDKDAVPARVSLGVTTLLTMTTQAS
GINAKLPPVSYIKAVDVWIGVCLAFIFGALLEYALVNYHGRQEFLKKEKKK
Number of residues
351
Molecular Weight
40736.84
Theoretical pI
Not Available
GO Classification
Functions
extracellular ligand-gated ion channel activity / transmembrane signaling receptor activity
Components
integral component of membrane / plasma membrane
General Function
Not Available
Specific Function
Extracellular ligand-gated ion channel activity
Pfam Domain Function
Transmembrane Regions
254-276 317-336
Cellular Location
Not Available
Chromosome Location
Not Available
Locus
Not Available
External Identifiers
ResourceLink
UniProtKB IDQ25634
UniProtKB Entry NameQ25634_ONCVO
General References
  1. Cully DF, Wilkinson H, Vassilatis DK, Etter A, Arena JP: Molecular biology and electrophysiology of glutamate-gated chloride channels of invertebrates. Parasitology. 1996;113 Suppl:S191-200. [Article]

Drug Relations

Drug Relations
DrugBank IDNameDrug groupPharmacological action?ActionsDetails
DB11431Moxidectinapproved, investigational, vet_approvedyesbinderDetails