Phenazine biosynthesis protein PhzG
Details
- Name
- Phenazine biosynthesis protein PhzG
- Synonyms
- 1.4.-.-
- Gene Name
- phzG
- Organism
- Pseudomonas fluorescens
- Amino acid sequence
>lcl|BSEQ0016969|Phenazine biosynthesis protein PhzG MNGSIQGKPLLGKGMSESLTGTLDAPFPEYQTLPADPMSVLHNWLERARRVGIREPRALA LATADSQGRPSTRIVVISEISDAGVVFSTHAGSQKGRELLHNPWASGVLYWRETSQQIIL NGQAVRLPNAKADDAWLKRPYATHPMSSVSRQSEELQDVQAMRNAARQLAELQGPLPRPE GYCVFELRLESLEFWGNGQERLHERLRYDRSDTGWNVRRLQP
- Number of residues
- 222
- Molecular Weight
- 24934.955
- Theoretical pI
- 9.05
- GO Classification
- FunctionsFMN binding / pyridoxamine-phosphate oxidase activityProcessespathogenesis / phenazine biosynthetic process / pyridoxine biosynthetic process
- General Function
- Pyridoxamine-phosphate oxidase activity
- Specific Function
- Involved in the biosynthesis of the antibiotic phenazine, a nitrogen-containing heterocyclic molecule having important roles in virulence, competition and biological control. Probably catalyzes the final step in the conversion of trans-2,3-dihydro-3-hydroxyanthranilic acid (DHHA) to phenazine-1-carboxylic acid (PCA).
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0005931|669 bp ATGAACGGCTCAATACAAGGCAAGCCGCTGTTGGGTAAAGGCATGTCGGAATCCCTCACC GGCACATTGGATGCGCCCTTCCCCGAATATCAGACACTGCCCGCCGACCCCATGAGCGTG CTGCACAATTGGCTGGAGCGTGCGCGCCGCGTGGGCATCCGCGAGCCCAGGGCGCTGGCG CTGGCCACCGCCGACAGCCAGGGCCGGCCCTCCACGCGTATCGTGGTGATCAGCGAGATC AGTGACGCCGGCGTGGTGTTCAGCACCCATGCCGGCAGCCAGAAAGGCCGTGAACTGCTC CACAACCCCTGGGCTTCGGGCGTGCTGTATTGGCGCGAAACCAGTCAGCAAATCATCCTC AATGGCCAGGCCGTGCGCTTGCCGAACGCCAAGGCCGATGATGCCTGGCTCAAGCGCCCT TATGCCACGCACCCGATGTCATCGGTGTCTCGCCAGAGTGAAGAACTGCAGGACGTGCAG GCCATGCGCAACGCCGCCAGGCAACTTGCCGAGCTGCAGGGTCCACTGCCGCGTCCGGAG GGATATTGCGTGTTCGAGTTGCGCCTTGAATCGCTGGAGTTCTGGGGAAATGGGCAGGAG CGCTTGCATGAGCGGTTGCGGTATGACCGCAGCGATACAGGCTGGAACGTGCGGCGTTTG CAGCCCTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q51793 UniProtKB Entry Name PHZG_PSEFL GenBank Gene ID L48616 - General References
- Mavrodi DV, Ksenzenko VN, Bonsall RF, Cook RJ, Boronin AM, Thomashow LS: A seven-gene locus for synthesis of phenazine-1-carboxylic acid by Pseudomonas fluorescens 2-79. J Bacteriol. 1998 May;180(9):2541-8. [Article]
- Parsons JF, Calabrese K, Eisenstein E, Ladner JE: Structure of the phenazine biosynthesis enzyme PhzG. Acta Crystallogr D Biol Crystallogr. 2004 Nov;60(Pt 11):2110-3. Epub 2004 Oct 20. [Article]