Proteasome subunit alpha type
Details
- Name
- Proteasome subunit alpha type
- Synonyms
- 3.4.25.1
- Gene Name
- Not Available
- Organism
- Plasmodium falciparum (isolate 3D7)
- Amino acid sequence
>lcl|BSEQ0051476|Proteasome subunit alpha type MFSTRSEYDRGVNTFSPEGRLFQVEYALGAIKLGSTAVGICVNDGVILASERRISSTLIE KDSVEKLLSIDDHIGCAMSGLMADARTLIDYARVECNHYKFIYNENINIKSCVELISELA LDFSNLSDSKRKKIMSRPFGVALLIGGVDKNGPCLWYTEPSGTNTRFSAASIGSAQEGAE LLLQENYKKDMTFEQAEILALTVLRQVMEDKLSTSNVEICAIKKSDQTFYKYNTDDISRI IDVLPSPVYPTIDMTA
- Number of residues
- 256
- Molecular Weight
- 28388.035
- Theoretical pI
- Not Available
- GO Classification
- Functionsendopeptidase activity / threonine-type endopeptidase activityProcessesproteasome-mediated ubiquitin-dependent protein catabolic process / ubiquitin-dependent protein catabolic processComponentscytoplasm / nucleus / proteasome core complex, alpha-subunit complex
- General Function
- Not Available
- Specific Function
- Endopeptidase activity
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0051477|Proteasome subunit alpha type ATGTTTTCAACAAGGAGTGAATATGATAGGGGAGTAAATACCTTTTCTCCTGAAGGACGA CTTTTTCAAGTTGAATATGCCTTAGGGGCGATAAAACTTGGTAGTACGGCTGTAGGTATT TGTGTGAACGATGGAGTGATATTAGCATCCGAGAGAAGAATTTCCTCAACACTTATCGAA AAAGATTCCGTTGAGAAATTATTATCGATAGATGATCATATTGGTTGTGCGATGAGTGGT TTGATGGCTGATGCAAGAACATTAATTGATTATGCAAGAGTCGAGTGTAATCATTATAAA TTTATTTATAATGAGAATATAAATATAAAGTCATGTGTAGAACTAATATCTGAATTAGCT TTAGATTTTTCTAATTTGTCTGATAGTAAAAGAAAAAAGATTATGAGCAGACCATTCGGA GTTGCTTTATTAATTGGTGGTGTCGATAAAAACGGACCATGTTTATGGTATACTGAACCT TCAGGAACCAATACAAGATTTTCAGCAGCTTCTATAGGTTCAGCACAAGAAGGAGCAGAA TTATTATTACAAGAAAATTATAAAAAAGATATGACATTTGAACAAGCTGAAATTTTAGCT CTTACGGTTTTAAGACAAGTTATGGAAGATAAACTTTCAACATCAAATGTTGAAATATGT GCTATAAAAAAATCAGATCAAACTTTTTATAAATATAATACGGATGATATATCTAGAATT ATTGACGTATTACCATCACCCGTTTATCCCACCATAGACATGACAGCATAG
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q8IBI3 UniProtKB Entry Name Q8IBI3_PLAF7 - General References
- Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, Carlton JM, Pain A, Nelson KE, Bowman S, Paulsen IT, James K, Eisen JA, Rutherford K, Salzberg SL, Craig A, Kyes S, Chan MS, Nene V, Shallom SJ, Suh B, Peterson J, Angiuoli S, Pertea M, Allen J, Selengut J, Haft D, Mather MW, Vaidya AB, Martin DM, Fairlamb AH, Fraunholz MJ, Roos DS, Ralph SA, McFadden GI, Cummings LM, Subramanian GM, Mungall C, Venter JC, Carucci DJ, Hoffman SL, Newbold C, Davis RW, Fraser CM, Barrell B: Genome sequence of the human malaria parasite Plasmodium falciparum. Nature. 2002 Oct 3;419(6906):498-511. [Article]
- Hall N, Pain A, Berriman M, Churcher C, Harris B, Harris D, Mungall K, Bowman S, Atkin R, Baker S, Barron A, Brooks K, Buckee CO, Burrows C, Cherevach I, Chillingworth C, Chillingworth T, Christodoulou Z, Clark L, Clark R, Corton C, Cronin A, Davies R, Davis P, Dear P, Dearden F, Doggett J, Feltwell T, Goble A, Goodhead I, Gwilliam R, Hamlin N, Hance Z, Harper D, Hauser H, Hornsby T, Holroyd S, Horrocks P, Humphray S, Jagels K, James KD, Johnson D, Kerhornou A, Knights A, Konfortov B, Kyes S, Larke N, Lawson D, Lennard N, Line A, Maddison M, McLean J, Mooney P, Moule S, Murphy L, Oliver K, Ormond D, Price C, Quail MA, Rabbinowitsch E, Rajandream MA, Rutter S, Rutherford KM, Sanders M, Simmonds M, Seeger K, Sharp S, Smith R, Squares R, Squares S, Stevens K, Taylor K, Tivey A, Unwin L, Whitehead S, Woodward J, Sulston JE, Craig A, Newbold C, Barrell BG: Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13. Nature. 2002 Oct 3;419(6906):527-31. [Article]
- Li H, O'Donoghue AJ, van der Linden WA, Xie SC, Yoo E, Foe IT, Tilley L, Craik CS, da Fonseca PC, Bogyo M: Structure- and function-based design of Plasmodium-selective proteasome inhibitors. Nature. 2016 Feb 11;530(7589):233-6. doi: 10.1038/nature16936. [Article]