Glyceraldehyde-3-phosphate dehydrogenase

Details

Name

Glyceraldehyde-3-phosphate dehydrogenase

Synonyms

• 1.2.1.12

Gene Name

GAPDH

Organism

Plasmodium falciparum (isolate 3D7)

Amino acid sequence

>lcl|BSEQ0051361|Glyceraldehyde-3-phosphate dehydrogenase
MAVTKLGINGFGRIGRLVFRAAFGRKDIEVVAINDPFMDLNHLCYLLKYDSVHGQFPCEV
THADGFLLIGEKKVSVFAEKDPSQIPWGKCQVDVVCESTGVFLTKELASSHLKGGAKKVI
MSAPPKDDTPIYVMGINHHQYDTKQLIVSNASCTTNCLAPLAKVINDRFGIVEGLMTTVH
ASTANQLVVDGPSKGGKDWRAGRCALSNIIPASTGAAKAVGKVLPELNGKLTGVAFRVPI
GTVSVVDLVCRLQKPAKYEEVALEIKKAAEGPLKGILGYTEDEVVSQDFVHDNRSSIFDM
KAGLALNDNFFKLVSWYDNEWGYSNRVLDLAVHITNN

Number of residues

337

Molecular Weight

36634.97

Theoretical pI

Not Available

GO Classification

Functions

glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity / NAD binding / NADP binding

Processes

gluconeogenesis / glycolytic process

Components

cytosol / membrane

General Function

Not Available

Specific Function

Glyceraldehyde-3-phosphate dehydrogenase (nad+) (phosphorylating) activity

Pfam Domain Function

• Gp_dh_C (PF02800)
• Gp_dh_N (PF00044)

Transmembrane Regions

Not Available

Cellular Location

Not Available

Gene sequence

>lcl|BSEQ0051362|Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)
ATGGCAGTAACAAAACTTGGAATTAATGGATTTGGTCGTATCGGACGTTTAGTATTTAGA
GCAGCCTTTGGAAGGAAAGATATCGAAGTAGTTGCTATTAACGACCCATTTATGGACCTT
AACCACTTATGCTATCTCTTGAAATACGATTCAGTACATGGTCAATTTCCATGTGAGGTA
ACCCACGCTGATGGATTTTTATTAATCGGAGAAAAGAAAGTCAGTGTTTTTGCTGAAAAG
GATCCATCTCAAATTCCTTGGGGAAAATGCCAAGTAGATGTTGTATGTGAATCAACTGGT
GTATTTTTAACCAAAGAATTAGCTAGCAGTCACCTTAAGGGAGGAGCCAAGAAGGTTATT
ATGTCCGCCCCACCAAAGGATGACACCCCAATTTATGTTATGGGTATTAACCACCACCAA
TATGATACCAAACAACTTATTGTTTCCAATGCATCATGTACCACAAACTGCTTAGCTCCA
TTAGCTAAAGTTATTAATGATCGTTTTGGAATTGTTGAAGGTTTAATGACCACCGTTCAT
GCATCCACTGCTAACCAATTAGTTGTTGATGGTCCATCAAAGGGTGGTAAGGACTGGAGA
GCAGGTAGATGTGCATTATCCAACATTATTCCAGCTTCCACTGGTGCAGCTAAAGCTGTA
GGTAAAGTTTTACCTGAACTTAATGGAAAATTAACAGGTGTAGCTTTCAGAGTACCAATT
GGAACTGTATCAGTTGTTGATTTAGTTTGCAGATTACAAAAACCAGCAAAATATGAAGAA
GTTGCTTTAGAAATTAAAAAAGCTGCTGAAGGTCCACTTAAAGGAATCTTAGGATACACT
GAAGATGAAGTTGTTTCTCAAGATTTCGTTCATGATAACAGATCATCAATCTTTGACATG
AAAGCTGGTTTAGCCTTAAACGACAATTTCTTCAAATTAGTTTCATGGTACGATAATGAA
TGGGGATACTCAAACCGTGTTCTTGATTTAGCCGTACACATTACTAACAACTAA

Chromosome Location

Not Available

Locus

Not Available

External Identifiers

Resource	Link
UniProtKB ID	Q8IKK7
UniProtKB Entry Name	Q8IKK7_PLAF7

General References

1. Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, Carlton JM, Pain A, Nelson KE, Bowman S, Paulsen IT, James K, Eisen JA, Rutherford K, Salzberg SL, Craig A, Kyes S, Chan MS, Nene V, Shallom SJ, Suh B, Peterson J, Angiuoli S, Pertea M, Allen J, Selengut J, Haft D, Mather MW, Vaidya AB, Martin DM, Fairlamb AH, Fraunholz MJ, Roos DS, Ralph SA, McFadden GI, Cummings LM, Subramanian GM, Mungall C, Venter JC, Carucci DJ, Hoffman SL, Newbold C, Davis RW, Fraser CM, Barrell B: Genome sequence of the human malaria parasite Plasmodium falciparum. Nature. 2002 Oct 3;419(6906):498-511. [Article]

Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details
DB11638	Artenimol	approved, experimental, investigational	unknown	ligand	Details