HAP protein
Details
- Name
- HAP protein
- Synonyms
- Plasmepsin III
- Gene Name
- Not Available
- Organism
- Plasmodium falciparum (isolate 3D7)
- Amino acid sequence
>lcl|BSEQ0051494|HAP protein MNLTIKEEDFTNTFMKNEESFNTFRVTKVKRWNAKRLFKILFVTVFIVLAGGFSYYIFEN FVFQKNRKINHIIKTSKYSTVGFNIENSYDRLMKTIKEHKLKNYIKESVKLFNKGLTKKS YLGSEFDNVELKDLANVLSFGEAKLGDNGQKFNFLFHTASSNVWVPSIKCTSESCESKNH YDSSKSKTYEKDDTPVKLTSKAGTISGIFSKDLVTIGKLSVPYKFIEMTEIVGFEPFYSE SDVDGVFGLGWKDLSIGSIDPYIVELKTQNKIEQAVYSIYLPPENKNKGYLTIGGIEERF FDGPLNYEKLNHDLMWQVDLDVHFGNVSSKKANVILDSATSVITVPTEFFNQFVESASVF KVPFLSLYVTTCGNTKLPTLEYRSPNKVYTLEPKQYLEPLENIFSALCMLNIVPIDLEKN TFVLGDPFMRKYFTVYDYDNHTVGFALAKNL
- Number of residues
- 451
- Molecular Weight
- 51692.85
- Theoretical pI
- Not Available
- GO Classification
- Functionsaspartic-type endopeptidase activity / metal ion bindingProcessesprotein catabolic process / proteolysisComponentsfood vacuole / integral component of membrane
- General Function
- Not Available
- Specific Function
- Aspartic-type endopeptidase activity
- Pfam Domain Function
- Asp (PF00026)
- Transmembrane Regions
- 37-58
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0051495|HAP protein ATGAATTTAACCATTAAAGAAGAAGATTTTACCAACACCTTCATGAAAAATGAAGAATCC TTTAACACGTTTCGAGTAACTAAAGTAAAAAGATGGAATGCTAAAAGATTATTTAAAATA TTATTTGTGACAGTTTTCATAGTTTTGGCAGGAGGTTTTTCTTATTATATTTTTGAAAAT TTCGTTTTTCAAAAGAACCGTAAAATTAATCACATAATTAAGACTTCAAAATATTCGACA GTAGGATTTAATATTGAAAATTCTTATGATAGACTTATGAAAACAATTAAAGAGCATAAA TTAAAAAATTATATAAAAGAATCAGTAAAACTTTTTAATAAAGGTTTAACCAAAAAAAGT TATTTAGGTAGTGAGTTTGATAATGTGGAATTAAAAGATTTAGCAAATGTATTATCTTTT GGAGAGGCAAAGCTTGGAGATAATGGTCAAAAATTTAATTTCTTATTCCATACAGCTTCA TCTAATGTATGGGTACCCAGTATAAAATGTACATCAGAGTCTTGTGAAAGTAAAAATCAT TATGATTCATCAAAATCAAAAACATATGAAAAAGATGATACGCCTGTTAAATTGACAAGT AAAGCTGGTACAATAAGTGGAATATTTAGTAAAGATTTAGTAACTATTGGTAAATTATCA GTACCCTATAAATTTATTGAAATGACGGAAATTGTTGGATTTGAACCTTTTTATTCTGAA TCAGACGTTGATGGTGTTTTCGGTTTAGGATGGAAAGATTTATCCATAGGCTCTATAGAT CCATATATTGTAGAATTAAAAACACAAAATAAAATTGAACAAGCCGTTTATTCCATTTAT TTACCACCAGAAAACAAAAATAAAGGTTATTTAACCATAGGAGGTATCGAAGAAAGATTC TTTGATGGACCATTGAACTATGAAAAATTAAATCACGATTTAATGTGGCAAGTTGATTTA GATGTACATTTTGGTAATGTATCTTCCAAAAAAGCAAACGTTATTTTAGATAGTGCCACC AGTGTCATAACTGTACCAACAGAATTTTTTAATCAATTCGTAGAATCTGCAAGTGTTTTC AAAGTTCCATTCTTATCTTTGTATGTAACCACTTGTGGTAACACGAAATTACCAACACTC GAATATCGTTCACCAAATAAAGTATATACTTTAGAACCTAAACAATACCTTGAACCATTA GAAAATATATTCTCAGCATTATGTATGCTTAACATTGTACCTATTGATTTAGAAAAAAAT ACCTTTGTTCTAGGTGACCCATTTATGAGAAAATATTTTACCGTTTATGATTACGATAAT CACACCGTTGGATTTGCTTTAGCCAAAAATTTATAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q8IM15 UniProtKB Entry Name Q8IM15_PLAF7 - General References
- Gardner MJ, Hall N, Fung E, White O, Berriman M, Hyman RW, Carlton JM, Pain A, Nelson KE, Bowman S, Paulsen IT, James K, Eisen JA, Rutherford K, Salzberg SL, Craig A, Kyes S, Chan MS, Nene V, Shallom SJ, Suh B, Peterson J, Angiuoli S, Pertea M, Allen J, Selengut J, Haft D, Mather MW, Vaidya AB, Martin DM, Fairlamb AH, Fraunholz MJ, Roos DS, Ralph SA, McFadden GI, Cummings LM, Subramanian GM, Mungall C, Venter JC, Carucci DJ, Hoffman SL, Newbold C, Davis RW, Fraser CM, Barrell B: Genome sequence of the human malaria parasite Plasmodium falciparum. Nature. 2002 Oct 3;419(6906):498-511. [Article]
- Bhaumik P, Xiao H, Parr CL, Kiso Y, Gustchina A, Yada RY, Wlodawer A: Crystal structures of the histo-aspartic protease (HAP) from Plasmodium falciparum. J Mol Biol. 2009 May 8;388(3):520-40. doi: 10.1016/j.jmb.2009.03.011. Epub 2009 Mar 11. [Article]