Methionine adenosyltransferase 2 subunit beta
Details
- Name
- Methionine adenosyltransferase 2 subunit beta
- Synonyms
- MAT II beta
- Methionine adenosyltransferase II beta
- Putative dTDP-4-keto-6-deoxy-D-glucose 4-reductase
- TGR
- Gene Name
- MAT2B
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0004274|Methionine adenosyltransferase 2 subunit beta MVGREKELSIHFVPGSCRLVEEEVNIPNRRVLVTGATGLLGRAVHKEFQQNNWHAVGCGF RRARPKFEQVNLLDSNAVHHIIHDFQPHVIVHCAAERRPDVVENQPDAASQLNVDASGNL AKEAAAVGAFLIYISSDYVFDGTNPPYREEDIPAPLNLYGKTKLDGEKAVLENNLGAAVL RIPILYGEVEKLEESAVTVMFDKVQFSNKSANMDHWQQRFPTHVKDVATVCRQLAEKRML DPSIKGTFHWSGNEQMTKYEMACAIADAFNLPSSHLRPITDSPVLGAQRPRNAQLDCSKL ETLGIGQRTPFRIGIKESLWPFLIDKRWRQTVFH
- Number of residues
- 334
- Molecular Weight
- 37551.535
- Theoretical pI
- 7.39
- GO Classification
- Functionsenzyme binding / methionine adenosyltransferase regulator activityProcessesmethylation / one-carbon metabolic process / regulation of catalytic activity / S-adenosylmethionine biosynthetic process / small molecule metabolic process / xenobiotic metabolic processComponentscytosol / extracellular exosome / intracellular / methionine adenosyltransferase complex / mitochondrion / nucleus
- General Function
- Methionine adenosyltransferase regulator activity
- Specific Function
- Non-catalytic regulatory subunit of S-adenosylmethionine synthetase 2 (MAT2A), an enzyme that catalyzes the formation of S-adenosylmethionine from methionine and ATP. Regulates the activity of S-adenosylmethionine synthetase 2 by changing its kinetic properties, rendering the enzyme more susceptible to S-adenosylmethionine inhibition.
- Pfam Domain Function
- RmlD_sub_bind (PF04321)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0011574|Methionine adenosyltransferase 2 subunit beta (MAT2B) ATGGTGGGGCGGGAGAAAGAGCTCTCTATACACTTTGTTCCCGGGAGCTGTCGGCTGGTG GAGGAGGAAGTTAACATCCCTAATAGGAGGGTTCTGGTTACTGGTGCCACTGGGCTTCTT GGCAGAGCTGTACACAAAGAATTTCAGCAGAATAATTGGCATGCAGTTGGCTGTGGTTTC AGAAGAGCAAGACCAAAATTTGAACAGGTTAATCTGTTGGATTCTAATGCAGTTCATCAC ATCATTCATGATTTTCAGCCCCATGTTATAGTACATTGTGCAGCAGAGAGAAGACCAGAT GTTGTAGAAAATCAGCCAGATGCTGCCTCTCAACTTAATGTGGATGCTTCTGGGAATTTA GCAAAGGAAGCAGCTGCTGTTGGAGCATTTCTCATCTACATTAGCTCAGATTATGTATTT GATGGAACAAATCCACCTTACAGAGAGGAAGACATACCAGCTCCCCTAAATTTGTATGGC AAAACAAAATTAGATGGAGAAAAGGCTGTCCTGGAGAACAATCTAGGAGCTGCTGTTTTG AGGATTCCTATTCTGTATGGGGAAGTTGAAAAGCTCGAAGAAAGTGCTGTGACTGTTATG TTTGATAAAGTGCAGTTCAGCAACAAGTCAGCAAACATGGATCACTGGCAGCAGAGGTTC CCCACACATGTCAAAGATGTGGCCACTGTGTGCCGGCAGCTAGCAGAGAAGAGAATGCTG GATCCATCAATTAAGGGAACCTTTCACTGGTCTGGCAATGAACAGATGACTAAGTATGAA ATGGCATGTGCAATTGCAGATGCCTTCAACCTCCCCAGCAGTCACTTAAGACCTATTACT GACAGCCCTGTCCTAGGAGCACAACGTCCGAGAAATGCTCAGCTTGACTGCTCCAAATTG GAGACCTTGGGCATTGGCCAACGAACACCATTTCGAATTGGAATCAAAGAATCACTTTGG CCTTTCCTCATTGACAAGAGATGGAGACAAACGGTCTTTCATTAG
- Chromosome Location
- 5
- Locus
- 5q34-q35.1
- External Identifiers
Resource Link UniProtKB ID Q9NZL9 UniProtKB Entry Name MAT2B_HUMAN GenBank Protein ID 6815285 GenBank Gene ID AF182814 GenAtlas ID MAT2B HGNC ID HGNC:6905 - General References
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