Mitochondrial peptide methionine sulfoxide reductase
Details
- Name
- Mitochondrial peptide methionine sulfoxide reductase
- Synonyms
- 1.8.4.11
- Peptide Met(O) reductase
- Peptide-methionine (S)-S-oxide reductase
- PMSR
- Protein-methionine-S-oxide reductase
- Gene Name
- MSRA
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0000339|Mitochondrial peptide methionine sulfoxide reductase MLSATRRACQLLLLHSLFPVPRMGNSASNIVSPQEALPGRKEQTPVAAKHHVNGNRTVEP FPEGTQMAVFGMGCFWGAERKFWVLKGVYSTQVGFAGGYTSNPTYKEVCSEKTGHAEVVR VVYQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPTSAKQMEAALSSKENYQ KVLSEHGFGPITTDIREGQTFYYAEDYHQQYLSKNPNGYCGLGGTGVSCPVGIKK
- Number of residues
- 235
- Molecular Weight
- 26132.42
- Theoretical pI
- 8.21
- GO Classification
- Functionspeptide-methionine (S)-S-oxide reductase activityProcessescellular protein modification process / methionine metabolic process / protein repair / response to oxidative stressComponentsactin cytoskeleton / cytoplasm / extracellular exosome / membrane / mitochondrion / nucleoplasm
- General Function
- Peptide-methionine (s)-s-oxide reductase activity
- Specific Function
- Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
- Pfam Domain Function
- PMSR (PF01625)
- Transmembrane Regions
- Not Available
- Cellular Location
- Mitochondrion
- Gene sequence
>lcl|BSEQ0018928|Mitochondrial peptide methionine sulfoxide reductase (MSRA) ATGCTCTCGGCCACCCGGAGGGCTTGCCAGCTCCTCCTCCTCCACAGCCTCTTTCCCGTC CCGAGGATGGGCAACTCGGCCTCGAACATCGTCAGCCCCCAGGAGGCCTTGCCGGGCCGG AAGGAACAGACCCCTGTAGCGGCCAAACATCATGTCAATGGCAACAGAACAGTCGAACCT TTCCCAGAGGGAACACAGATGGCTGTATTTGAAAAAACTGGCCATGCAGAAGTCGTCCGA GTGGTGTACCAGCCAGAACACATGAGTTTTGAGGAACTGCTCAAGGTCTTCTGGGAGAAT CACGACCCGACCCAAGGTATGCGCCAGGGGAACGACCATGGCACTCAGTACCGCTCGGCC ATCTACCCGACCTCTGCCAAGCAAATGGAGGCAGCCCTGAGCTCCAAAGAGAACTACCAA AAGGTTCTTTCAGAGCACGGCTTCGGCCCCATCACTACCGACATCCGGGAGGGACAGACT TTCTACTATGCGGAAGACTACCACCAGCAGTACCTGAGCAAGAACCCCAATGGCTACTGC GGCCTTGGGGGCACCGGCGTGTCCTGCCCAGTGGGTATTAAAAAATAA
- Chromosome Location
- 8
- Locus
- 8p23.1
- External Identifiers
Resource Link UniProtKB ID Q9UJ68 UniProtKB Entry Name MSRA_HUMAN GenBank Protein ID 6136945 GenBank Gene ID AJ242973 GenAtlas ID MSRA HGNC ID HGNC:7377 - General References
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