Microtubule-associated serine/threonine-protein kinase 1
Details
- Name
- Microtubule-associated serine/threonine-protein kinase 1
- Synonyms
- 2.7.11.1
- KIAA0973
- SAST
- Syntrophin-associated serine/threonine-protein kinase
- Gene Name
- MAST1
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0051846|Microtubule-associated serine/threonine-protein kinase 1 MSDSLWTALSNFSMPSFPGGSMFRRTKSCRTSNRKSLILTSTSPTLPRPHSPLPGHLGSS PLDSPRNFSPNTPAHFSFASSRRADGRRWSLASLPSSGYGTNTPSSTVSSSCSSQERLHQ LPYQPTVDELHFLSKHFGSTESITDEDGGRRSPAVRPRSRSLSPGRSPSSYDNEIVMMNH VYKERFPKATAQMEEKLRDFTRAYEPDSVLPLADGVLSFIHHQIIELARDCLTKSRDGLI TTVYFYELQENLEKLLQDAYERSESLEVAFVTQLVKKLLIIISRPARLLECLEFNPEEFY HLLEAAEGHAKEGHLVKTDIPRYIIRQLGLTRDPFPDVVHLEEQDSGGSNTPEQDDLSEG RSSKAKKPPGENDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAF VERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAE TVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAR EFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVI SDDILWPEGDEALPTEAQLLISSLLQTNPLVRLGAGGAFEVKQHSFFRDLDWTGLLRQKA EFIPHLESEDDTSYFDTRSDRYHHVNSYDEDDTTEEEPVEIRQFSSCSPRFSKVYSSMEQ LSQHEPKTPVAAAGSSKREPSTKGPEEKVAGKREGLGGLTLREKTWRGGSPEIKRFSASE ASFLEGEASPPLGARRRFSALLEPSRFSAPQEDEDEARLRRPPRPSSDPAGSLDARAPKE ETQGEGTSSAGDSEATDRPRPGDLCPPSKDGDASGPRATNDLVLRRARHQQMSGDVAVEK RPSRTGGKVIKSASATALSVMIPAVDPHGSSPLASPMSPRSLSSNPSSRDSSPSRDYSPA VSGLRSPITIQRSGKKYGFTLRAIRVYMGDTDVYSVHHIVWHVEEGGPAQEAGLCAGDLI THVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENTSIRIGPARRSSYKAKMARRNKRP SAKEGQESKKRSSLFRKITKQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHGLPARSPTHS YRSTPDSAYLGASSQSSSPASSTPNSPASSASHHIRPSTLHGLSPKLHRQYRSARCKSAG NIPLSPLAHTPSPTQASPPPLPGHTVGSSHTTQSFPAKLHSSPPVVRPRPKSAEPPRSPL LKRVQSAEKLGASLSADKKGALRKHSLEVGHPDFRKDFHGELALHSLAESDGETPPVEGL GAPRQVAVRRLGRQESPLSLGADPLLPEGASRPPVSSKEKESPGGAEACTPPRATTPGGR TLERDVGCTRHQSVQTEDGTGGMARAVAKAALSPVQEHETGRRSSSGEAGTPLVPIVVEP ARPGAKAVVPQPLGADSKGLQEPAPLAPSVPEAPRGRERWVLEVVEERTTLSGPRSKPAS PKLSPEPQTPSLAPAKCSAPSSAVTPVPPASLLGSGTKPQVGLTSRCPAEAVPPAGLTKK GVSSPAPPGP
- Number of residues
- 1570
- Molecular Weight
- 170675.235
- Theoretical pI
- Not Available
- GO Classification
- FunctionsATP binding / magnesium ion binding / protein serine/threonine kinase activityProcessescytoskeleton organization / intracellular signal transduction / peptidyl-serine phosphorylation / protein phosphorylationComponentscytoplasm / cytoskeleton / intracellular / plasma membrane
- General Function
- Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins (By similarity).
- Specific Function
- Atp binding
- Pfam Domain Function
- Transmembrane Regions
- Not Available
- Cellular Location
- Cell membrane
- Gene sequence
>lcl|BSEQ0051847|Microtubule-associated serine/threonine-protein kinase 1 (MAST1) ATGTCTGACTCTCTCTGGACCGCGCTTTCTAATTTCTCGATGCCCTCCTTCCCCGGCGGC AGTATGTTCCGCCGCACCAAGAGCTGCCGCACCAGTAATCGGAAAAGCCTCATCCTGACC AGCACTTCACCCACGCTACCGAGACCCCACTCCCCGCTGCCAGGTCACCTAGGCAGCAGT CCCCTGGACAGCCCCCGAAACTTCTCCCCCAACACCCCCGCCCACTTCTCGTTTGCCTCC TCCCGAAGGGCGGACGGACGCCGGTGGTCTCTGGCCTCGCTCCCTTCATCTGGCTATGGC ACCAACACGCCCAGTTCCACCGTCTCGTCCTCCTGCTCCTCCCAGGAGCGCCTTCACCAG CTGCCCTACCAGCCCACGGTGGACGAGCTCCACTTCCTCTCCAAACACTTCGGGAGCACC GAGAGCATCACAGACGAGGATGGTGGCCGTCGCTCCCCAGCCGTGCGGCCCCGCTCACGG AGCCTCAGCCCCGGGCGCTCCCCCTCCTCCTACGACAACGAGATCGTGATGATGAATCAC GTCTACAAGGAGAGGTTCCCGAAGGCCACTGCGCAGATGGAGGAGAAGCTGCGCGACTTT ACCCGCGCCTACGAACCCGACAGCGTTCTGCCTCTGGCCGATGGCGTGCTCAGCTTCATC CACCACCAGATCATCGAGCTGGCCCGGGACTGCCTGACCAAGTCCCGTGACGGCCTCATC ACCACGGTCTACTTCTATGAATTGCAGGAGAACCTGGAGAAGCTCCTTCAAGACGCCTAT GAACGCTCTGAGAGCTTGGAGGTGGCCTTCGTTACTCAGCTGGTGAAGAAGTTGCTTATT ATCATCTCACGCCCTGCGAGGCTGCTGGAGTGCCTGGAATTCAACCCCGAGGAGTTCTAC CACCTGCTGGAGGCGGCCGAAGGACACGCCAAGGAGGGCCACCTTGTGAAGACGGACATC CCCCGCTACATCATCCGCCAGCTGGGCCTCACCCGTGACCCCTTTCCAGATGTGGTGCAT CTGGAGGAACAGGACAGTGGTGGTTCCAACACCCCTGAGCAAGACGATCTCTCTGAGGGC CGCAGCAGCAAGGCCAAGAAACCGCCGGGGGAGAATGACTTCGATACCATCAAGCTCATA AGCAACGGTGCCTACGGCGCTGTCTACCTGGTGCGGCACCGCGACACGCGGCAGCGCTTT GCCATGAAAAAGATCAACAAGCAGAACTTGATCCTCCGCAACCAGATCCAGCAGGCCTTT GTGGAGCGCGATATCCTCACCTTCGCCGAGAACCCGTTTGTGGTCGGCATGTTCTGCTCC TTTGAGACTCGGCGCCACCTCTGCATGGTCATGGAATATGTGGAAGGCGGCGACTGTGCC ACCCTGCTGAAGAATATTGGAGCGCTGCCCGTAGAGATGGCCCGCATGTACTTTGCTGAG ACGGTGCTAGCCCTGGAGTATTTGCACAACTATGGCATCGTGCACCGCGACCTCAAGCCT GACAACCTCCTTATCACCTCCATGGGTCACATCAAGCTCACAGATTTCGGCCTCTCCAAG ATGGGGCTCATGAGCCTCACCACCAACTTATATGAAGGCCACATCGAGAAGGACGCCCGA GAGTTCCTGGACAAACAGGTGTGTGGGACCCCAGAGTACATCGCGCCCGAGGTCATCCTG CGTCAAGGCTACGGCAAGCCAGTGGACTGGTGGGCTATGGGGATCATCCTCTACGAGTTC CTGGTGGGCTGTGTGCCCTTCTTCGGAGACACACCAGAGGAGCTATTTGGACAGGTCATC AGTGATGACATCCTGTGGCCCGAGGGGGATGAGGCCCTACCTACGGAGGCCCAACTCCTC ATATCCAGCCTCCTGCAGACCAACCCTCTGGTCAGGCTTGGGGCAGGCGGCGCTTTTGAG GTGAAGCAGCACAGTTTCTTTCGAGACCTGGACTGGACAGGGCTGCTGAGGCAGAAGGCC GAGTTCATCCCCCACCTAGAGTCGGAAGATGACACTAGCTACTTTGACACCCGCTCAGAC AGGTATCACCACGTGAACTCCTATGACGAGGATGACACGACGGAGGAGGAGCCCGTGGAA ATCCGCCAGTTCTCTTCCTGCTCTCCGCGCTTCAGCAAGGTGTATAGCAGCATGGAGCAG CTGTCGCAGCACGAGCCCAAGACCCCAGTAGCAGCTGCAGGGAGCAGCAAGCGGGAGCCG AGCACCAAGGGCCCCGAGGAGAAGGTGGCCGGCAAGCGGGAGGGGCTGGGCGGCCTGACC CTGCGTGAGAAGACCTGGAGAGGGGGCTCTCCGGAGATCAAGCGATTCTCCGCGTCCGAG GCCAGTTTCCTGGAGGGAGAGGCCAGTCCCCCTTTGGGCGCCCGCCGCCGTTTCTCGGCG CTGCTGGAGCCCAGCCGCTTCAGCGCCCCCCAAGAGGACGAGGATGAGGCCCGGCTGCGC AGGCCTCCCCGGCCCAGCTCCGACCCCGCGGGATCCCTGGATGCACGGGCCCCCAAAGAG GAGACTCAAGGGGAAGGCACCTCCAGCGCCGGGGACTCCGAGGCCACTGACCGTCCACGC CCAGGTGACCTCTGCCCACCCTCGAAGGATGGGGATGCATCAGGCCCAAGGGCTACCAAT GACTTGGTTCTGCGCCGGGCGCGGCACCAGCAGATGTCAGGGGATGTGGCAGTAGAGAAG AGGCCTTCTCGAACTGGGGGCAAAGTCATCAAATCAGCCTCAGCCACTGCCTTATCTGTC ATGATTCCTGCAGTGGACCCACATGGAAGTTCACCCCTTGCTAGTCCCATGTCTCCACGA TCTCTGTCCTCCAACCCATCCTCACGGGACTCCTCACCCAGCCGGGACTACTCACCAGCT GTCAGTGGGCTCCGCTCCCCCATCACCATCCAGCGCTCGGGCAAGAAGTATGGCTTCACA CTGCGTGCCATCCGTGTCTACATGGGTGACACGGATGTCTATAGTGTCCACCACATTGTC TGGCATGTGGAGGAAGGAGGCCCAGCCCAGGAGGCAGGACTCTGTGCTGGGGACCTCATC ACCCACGTGAATGGGGAGCCTGTGCATGGCATGGTGCATCCTGAGGTCGTGGAGCTGATC CTTAAGAGTGGCAACAAGGTAGCAGTGACCACAACGCCCTTCGAAAATACCTCTATCCGC ATTGGTCCCGCAAGGCGCAGCAGCTACAAGGCTAAAATGGCTCGGAGGAACAAGCGACCC TCCGCCAAGGAGGGCCAGGAGAGCAAGAAGCGCAGCTCCCTCTTCCGGAAGATCACGAAG CAGTCGAACCTGCTGCATACTAGCCGCTCGCTGTCGTCGCTGAACCGCTCGCTGTCATCC AGCGATAGTCTCCCGGGCTCGCCTACGCACGGGCTGCCGGCGCGCTCGCCCACGCACAGC TACCGCTCCACGCCTGACTCCGCCTACCTAGGCGCCTCATCCCAGAGCAGCTCCCCAGCC TCGAGCACGCCCAACTCGCCTGCGTCGTCGGCGTCGCACCACATTCGGCCCAGCACGCTG CACGGACTGTCGCCAAAGCTCCATCGCCAGTACCGCTCTGCGCGATGCAAGTCGGCCGGC AACATCCCTCTATCGCCGCTGGCACACACGCCGTCCCCCACGCAGGCGTCACCGCCGCCA CTGCCGGGCCACACGGTGGGCAGCTCGCACACTACTCAGAGCTTCCCGGCCAAACTGCAC TCATCGCCTCCCGTCGTGCGCCCGCGCCCCAAGAGTGCCGAGCCCCCTCGCTCGCCGCTC CTCAAGCGCGTGCAGTCGGCCGAGAAGCTGGGAGCCTCTTTGAGTGCGGACAAGAAGGGC GCGCTGCGCAAACACAGCCTCGAGGTGGGCCACCCGGATTTCCGCAAGGACTTCCATGGC GAGCTGGCGCTGCATAGCCTTGCCGAGTCCGACGGTGAGACGCCCCCAGTCGAGGGCCTT GGCGCGCCCCGGCAGGTCGCCGTCCGCCGCCTGGGCCGACAGGAGTCACCTTTGAGCCTG GGCGCGGACCCGTTGCTGCCCGAGGGTGCCTCCAGGCCACCAGTGTCGAGCAAGGAGAAG GAATCCCCGGGGGGCGCCGAGGCGTGCACCCCACCCCGCGCGACGACCCCCGGTGGCCGG ACCCTGGAGCGGGACGTCGGCTGCACGCGGCATCAGAGCGTGCAGACGGAGGATGGCACT GGCGGGATGGCCAGGGCTGTGGCCAAGGCGGCGCTGAGCCCGGTGCAGGAACACGAGACA GGCCGGCGCAGCAGCTCTGGCGAGGCGGGCACACCCCTGGTACCCATTGTCGTAGAGCCT GCGCGGCCCGGGGCTAAGGCTGTGGTGCCTCAGCCTCTGGGCGCGGACTCCAAGGGGTTG CAGGAACCCGCACCCCTGGCGCCTTCCGTGCCCGAGGCCCCCCGGGGCCGGGAGCGCTGG GTGTTGGAGGTGGTGGAGGAGCGCACCACGCTGAGCGGTCCTCGCTCCAAGCCCGCCTCC CCAAAGCTCTCCCCGGAGCCCCAGACACCCTCCCTAGCCCCAGCGAAGTGCAGTGCACCC AGCAGTGCAGTGACCCCAGTCCCACCCGCATCCCTCTTGGGCTCAGGCACCAAGCCTCAA GTGGGGCTGACCTCCCGGTGCCCTGCTGAAGCTGTGCCCCCAGCAGGCCTGACCAAAAAA GGAGTGTCCAGTCCCGCACCCCCGGGACCATAG
- Chromosome Location
- 19
- Locus
- 19p13.13
- External Identifiers
Resource Link UniProtKB ID Q9Y2H9 UniProtKB Entry Name MAST1_HUMAN HGNC ID HGNC:19034 - General References
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