Fumarate reductase flavoprotein subunit
Details
- Name
- Fumarate reductase flavoprotein subunit
- Synonyms
- 1.3.5.4
- Fe(3+)-induced flavocytochrome C3
- Ifc3
- Iron(III)-induced flavocytochrome C3
- Gene Name
- ifcA
- Organism
- Shewanella frigidimarina (strain NCIMB 400)
- Amino acid sequence
>lcl|BSEQ0012021|Fumarate reductase flavoprotein subunit MKLKYLVSAMALVVLSSGTAMAKTPDMGSFHADMGSCQSCHAKPIKVTDSETHENAQCKS CHGEYAELANDKLQFDPHNSHLGDINCTSCHKGHEEPKFYCNECHSFDIKPMPFSDAKKK KSWDDGWDQDKIQKAIAAGPSETTQVLVVGAGSAGFNASLAAKKAGANVILVDKAPFSGG NSMISAGGMNAVGTKQQTAHGVEDKVEWFIEDAMKGGRQQNDIKLVTILAEQSADGVQWL ESLGANLDDLKRSGGARVDRTHRPHGGKSSGPEIIDTLRKAAKEQGIDTRLNSRVVKLVV NDDHSVVGAVVHGKHTGYYMIGAKSVVLATGGYGMNKEMIAYYRPTMKDMTSSNNITATG DGVLMAKEIGASMTDIDWVQAHPTVGKDSRILISETVRGVGAVMVNKDGNRFISELTTRD KASDAILKQPGQFAWIIFDNQLYKKAKMVRGYDHLEMLYKGDTVEQLAKSTGMKVADLAK TVSDYNGYVASGKDTAFGRADMPLNMTQSPYYAVKVAPGIHHTMGGVAINTTASVLDLQS KPIDGLFAAGEVTGGVHGYNRLGGNAIADTVVFGRIAGDNAAKHALDK
- Number of residues
- 588
- Molecular Weight
- 62946.005
- Theoretical pI
- 7.69
- GO Classification
- Functionsmetal ion binding / succinate dehydrogenase activityComponentsperiplasmic space
- General Function
- Succinate dehydrogenase activity
- Specific Function
- Catalyzes unidirectional fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown.
- Pfam Domain Function
- FAD_binding_2 (PF00890)
- Transmembrane Regions
- Not Available
- Cellular Location
- Periplasm
- Gene sequence
>lcl|BSEQ0012022|Fumarate reductase flavoprotein subunit (ifcA) ATGAAACTAAAATATCTGGTATCAGCGATGGCATTGGTTGTGCTTTCCTCTGGTACTGCA ATGGCTAAAACCCCCGATATGGGGTCATTCCATGCTGACATGGGCAGTTGTCAATCTTGT CACGCCAAACCTATCAAGGTTACTGATAGCGAAACTCATGAAAATGCTCAGTGTAAATCA TGCCACGGAGAGTACGCTGAACTGGCTAATGACAAATTACAGTTTGACCCACACAATTCA CATTTAGGTGACATTAACTGTACTAGTTGCCATAAAGGCCATGAAGAACCAAAATTTTAC TGTAATGAGTGTCATTCATTTGATATCAAGCCGATGCCATTTTCTGATGCCAAGAAGAAA AAATCTTGGGACGACGGATGGGATCAAGACAAAATTCAAAAAGCGATTGCTGCAGGCCCA AGTGAAACAACGCAAGTATTAGTAGTCGGTGCGGGTAGTGCAGGTTTTAACGCATCATTA GCCGCTAAAAAAGCCGGTGCTAATGTTATTTTGGTGGATAAAGCACCGTTCAGTGGTGGT AATTCTATGATTTCAGCTGGTGGTATGAATGCTGTTGGAACTAAGCAGCAAACAGCTCAT GGTGTTGAAGATAAAGTTGAATGGTTTATCGAAGATGCCATGAAAGGCGGCCGTCAACAG AATGATATAAAACTGGTGACTATTCTTGCTGAACAGTCTGCTGATGGTGTGCAATGGTTA GAGTCTTTAGGTGCAAACTTAGATGACTTAAAACGCTCAGGTGGTGCTCGTGTCGACCGT ACTCATCGTCCACATGGAGGTAAAAGCTCTGGGCCAGAAATTATTGATACTTTACGCAAA GCGGCCAAAGAACAGGGTATTGATACACGACTAAACTCTCGTGTAGTTAAGTTAGTGGTT AATGACGATCATAGTGTTGTCGGCGCCGTGGTTCATGGTAAACATACTGGCTATTACATG ATTGGTGCTAAATCTGTTGTGCTAGCAACGGGTGGTTATGGCATGAATAAAGAAATGATT GCTTATTACCGTCCAACAATGAAAGACATGACCAGTTCGAACAACATTACCGCCACTGGT GATGGTGTATTGATGGCAAAAGAAATTGGTGCCAGCATGACCGATATCGACTGGGTTCAA GCTCACCCAACAGTGGGTAAAGACAGCCGTATTCTGATTTCAGAAACCGTCCGTGGTGTG GGCGCTGTGATGGTAAACAAAGACGGTAATCGCTTTATTAGCGAGTTAACAACTCGTGAC AAAGCATCTGATGCTATCTTAAAACAACCTGGCCAGTTTGCTTGGATTATTTTTGATAAC CAGTTATACAAAAAAGCCAAAATGGTACGCGGTTATGACCATTTAGAAATGCTTTACAAA GGCGATACTGTTGAACAGTTAGCGAAGAGCACCGGTATGAAAGTCGCTGATTTAGCTAAA ACAGTCTCTGACTACAATGGTTATGTAGCATCTGGTAAAGACACTGCGTTTGGTCGTGCT GATATGCCATTGAACATGACCCAAAGTCCTTACTATGCCGTTAAAGTTGCTCCTGGTATT CATCACACTATGGGTGGTGTCGCGATTAACACAACAGCGTCTGTACTTGACCTTCAAAGT AAGCCAATTGACGGTTTGTTTGCCGCAGGTGAAGTGACTGGTGGTGTTCATGGTTACAAC CGTTTGGGCGGTAATGCAATAGCAGATACCGTGGTCTTCGGTCGAATTGCAGGAGATAAC GCAGCCAAGCATGCTCTAGATAAATAG
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q9Z4P0 UniProtKB Entry Name FRD2_SHEFN GenBank Gene ID AJ236923 - General References
- Dobbin PS, Butt JN, Powell AK, Reid GA, Richardson DJ: Characterization of a flavocytochrome that is induced during the anaerobic respiration of Fe3+ by Shewanella frigidimarina NCIMB400. Biochem J. 1999 Sep 1;342 ( Pt 2):439-48. [Article]
- Bamford V, Dobbin PS, Richardson DJ, Hemmings AM: Open conformation of a flavocytochrome c3 fumarate reductase. Nat Struct Biol. 1999 Dec;6(12):1104-7. [Article]