Aldose 1-epimerase
Details
- Name
- Aldose 1-epimerase
- Synonyms
- 5.1.3.3
- Galactose mutarotase
- Gene Name
- galM
- Organism
- Lactococcus lactis
- Amino acid sequence
>lcl|BSEQ0012000|Aldose 1-epimerase MEIKIRDFGLGSDLISLTNKAGVTISFTNLGARIVDWQKDGKHLILGFDSAKEYLEKDAY PGATVGPTAGRIKDGLVKISGKDYILNQNEGPQTLHGGEESIHTKLWTYEVTDLGAEVQV KFSLVTNDGTNGYPGKIEMSVTHSFDDYNKWKIHYEAISDKDTVFNPTGHVYFNLNGDAS ESVENHGLRLAASRFVPLKDQTEIVRGDIVDIKNTDLDFRQEKQLSNAFNSNMEQVQLVK GIDHPFLLDQLGLDKEQARLTLDDTSISVFTDQPSIVIFTANFGDLGTLYHEKKQVHHGG ITFECQVSPGSEQIPELGDISLKAGEKYQATTIYSLHTK
- Number of residues
- 339
- Molecular Weight
- 37610.85
- Theoretical pI
- 5.01
- GO Classification
- Functionsaldose 1-epimerase activity / carbohydrate bindingProcessesgalactose metabolic process
- General Function
- Carbohydrate binding
- Specific Function
- Converts alpha-aldose to the beta-anomer.
- Pfam Domain Function
- Aldose_epim (PF01263)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0005568|1020 bp ATGGAAATTAAAATAAGAGATTTTGGCTTAGGAAGTGACTTAATTAGTCTAACCAATAAA GCAGGTGTCACAATTTCTTTTACAAATCTGGGCGCTCGGATTGTTGACTGGCAAAAAGAT GGAAAGCATCTGATTCTAGGCTTTGATTCAGCTAAAGAATATTTAGAAAAAGATGCCTAT CCTGGTGCAACAGTTGGACCTACAGCAGGAAGAATTAAGGATGGTTTGGTCAAAATTTCT GGAAAAGATTATATCTTAAATCAAAATGAAGGCCCTCAAACCTTACATGGTGGGGAAGAA AGTATTCATACTAAACTTTGGACATATGAAGTTACCGATTTAGGAGCTGAAGTTCAAGTC AAATTTTCCTTAGTTACTAATGACGGAACAAATGGTTATCCTGGTAAAATAGAAATGTCA GTAACTCATTCTTTTGATGATTACAATAAGTGGAAAATTCATTATGAGGCCATTTCTGAT AAAGACACTGTGTTTAATCCAACTGGGCATGTCTATTTTAATTTGAATGGTGATGCTAGT GAATCTGTTGAAAATCATGGACTTCGACTGGCCGCTTCAAGATTTGTTCCTTTAAAAGAC CAAACAGAAATTGTTCGTGGTGATATCGTTGATATAAAAAATACAGACTTGGATTTCCGT CAGGAAAAACAATTATCAAATGCCTTCAATTCTAATATGGAACAAGTTCAATTAGTTAAA GGAATTGACCATCCTTTCTTGTTAGACCAGTTAGGACTTGATAAAGAACAAGCTCGTTTA ACGCTTGATGATACTTCAATTTCAGTCTTTACCGACCAACCAAGTATTGTGATATTTACA GCAAATTTTGGTGATTTAGGAACTCTTTATCATGAGAAAAAGCAAGTGCACCATGGTGGA ATTACTTTTGAATGTCAAGTATCACCTGGGTCTGAGCAAATTCCAGAGCTTGGAGATATC AGCCTAAAAGCGGGAGAAAAATATCAAGCAACCACAATTTACAGCTTGCATACAAAATAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID Q9ZB17 UniProtKB Entry Name Q9ZB17_9LACT GenBank Gene ID U60828 - General References
- Thoden JB, Holden HM: High resolution X-ray structure of galactose mutarotase from Lactococcus lactis. J Biol Chem. 2002 Jun 7;277(23):20854-61. Epub 2002 Mar 20. [Article]
- Thoden JB, Kim J, Raushel FM, Holden HM: Structural and kinetic studies of sugar binding to galactose mutarotase from Lactococcus lactis. J Biol Chem. 2002 Nov 22;277(47):45458-65. Epub 2002 Sep 5. [Article]
- Thoden JB, Kim J, Raushel FM, Holden HM: The catalytic mechanism of galactose mutarotase. Protein Sci. 2003 May;12(5):1051-9. [Article]