Drug Carriers

Name
Drug Carriers
Accession Number
DBCAT000064
Description

Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.

Drugs
DrugDrug Description
Peginterferon alfa-2aA modified form of recombinant human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C viruses.
Peginterferon alfa-2bA purified form of human interferon used to stimulate the innate antiviral response in the treatment of hepatitis B and C, genital warts, and some cancers.
PegademaseA modified form of bovine adenosine deaminase used to treat adenosine deaminase deficiency, a condition which leads to the formation of adenosine metabolites which are cytotoxic to lymphocytes.
Amphotericin BAn antifungal used to treat fungal infections in neutropenic patients, cryptococcal meningitis in HIV infection, fungal infections, and leishmaniasis.
Oleoyl-estroneFor the treatment of obesity.
PolycarbophilPolycarbophil is used to treat constipation and to help maintain regular bowel movements.
Xanthan gumXanthan gum is a polysaccharide gum derived from* Xanthomonas campestris* by a pure-culture fermentation process and purified by recovery with isopropyl alcohol. The major constituents include D-glucose, D-mannose, and D-glucuronic...
TocofersolanA derivative of alpha tocopherol used to treat vitamin E deficiencies.
AstodrimerAstodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups.
Calcium polycarbophilA bulk forming laxative used to treat constipation.
CarbomerNot Annotated
Drugs & Drug Targets
DrugTargetType
Peginterferon alfa-2aInterferon alpha/beta receptor 2target
Peginterferon alfa-2aInterferon alpha/beta receptor 1target
Peginterferon alfa-2aCytochrome P450 1A2enzyme
Peginterferon alfa-2bInterferon alpha/beta receptor 1target
Peginterferon alfa-2bInterferon alpha/beta receptor 2target
Peginterferon alfa-2bCytochrome P450 1A2enzyme
Peginterferon alfa-2bCytochrome P450 2D6enzyme
Peginterferon alfa-2bCytochrome P450 2C9enzyme
PegademaseAdenosinetarget
PegademaseGrowth factor receptor-bound protein 2target
Amphotericin BErgosteroltarget
Amphotericin BCytochrome P450 3A4enzyme
TocofersolanP-glycoprotein 1target
TocofersolanLeukotriene-B(4) omega-hydroxylase 1enzyme
TocofersolanAlpha-tocopherol transfer proteintransporter
TocofersolanScavenger receptor class B member 1transporter
TocofersolanNiemann-Pick C1-like protein 1transporter
TocofersolanATP-binding cassette sub-family G member 5transporter
TocofersolanATP-binding cassette sub-family G member 8transporter
TocofersolanATP-binding cassette sub-family A member 1transporter
TocofersolanSEC14-like protein 4transporter
TocofersolanSEC14-like protein 2transporter
TocofersolanSEC14-like protein 3transporter
TocofersolanApolipoprotein B receptortransporter
TocofersolanCytochrome P450 3A4enzyme
AstodrimerEnvelope glycoprotein gp160target