Growth Hormone-Releasing Hormone
- Name
- Growth Hormone-Releasing Hormone
- Accession Number
- DBCAT000076
- Description
A peptide of 44 amino acids in most species that stimulates the release and synthesis of GROWTH HORMONE. GHRF (or GRF) is synthesized by neurons in the ARCUATE NUCLEUS of the HYPOTHALAMUS. After being released into the pituitary portal circulation, GHRF stimulates GH release by the SOMATOTROPHS in the PITUITARY GLAND.
- Drugs
Drug Drug Description Sermorelin For the treatment of dwarfism, prevention of HIV-induced weight loss Tesamorelin A growth hormone releasing factor (GRF) analog used to reduce excessive abdominal fat in HIV patients who have developed lipodystrophy. Hexapeptide-2 Not Annotated Pralmorelin Not Annotated - Drugs & Drug Targets
Drug Target Type Sermorelin Growth hormone-releasing hormone receptor target Tesamorelin Growth hormone-releasing hormone receptor target