Pituitary Hormones, Anterior

Hormones secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Structurally, they include polypeptide, protein, and glycoprotein molecules.
DrugDrug NameDrug Indication
DB01284TetracosactideFor use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.
DB01285CorticotropinFor use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.
DB04931AfamelanotideInvestigated for use/treatment in actinic keratosis, keratoses, skin cell studies, and skin infections/disorders.
DB00024Thyrotropin alfaFor detection of residueal or recurrent thyroid cancer
DB00032MenotropinsFor the treatment of female infertility
DB00052SomatotropinFor treatment of dwarfism, acromegaly and prevention of HIV-induced weight loss
DB00066FollitropinIn women having been diagnosed with primary ovarian failure, it is used in combination with human chorionic gonadotropin (hCG) to assist in ovulation and fertility. In men with hypogonadotrophic hypogonadism, it is used to induce spermatogenesis. Follitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for use in gamete intrafallopian transfer (GIFT) or in vitro fertilization (IVF).
DB00082PegvisomantPegvisomant is a growth hormone receptor antagonist used for the treatment of acromegaly.
DB00094UrofollitropinFor treatment of female infertility
DB09066Corifollitropin alfaControlled ovarian stimulation [L2273] in cases of women who are undergoing fertility treatment to stimulate the development of more than one mature egg simultaneously in the ovaries in combination with a gonadotrophin-releasing hormone (GnRH) antagonist (a type of medicine also used in fertility treatments)[L2270].
DB09098SomatremSomatrem is a recombinant human growth hormone indicated for: (a) treatment of paediatric patients with growth failure due to growth hormone deficiency (GHD), (b) treatment of paediatric patients with growth failure due to idiopathic short stature (ISS), (c) treatment of paediatric patients with growth failure due to Turner syndrome (TS), (d) treatment of paediatric patients with growth failure due to chronic kidney disease (CKD) up to the time of renal transplantation, (e) treatment of adults with childhood-onset GHD, or (f) treatment of adults with adult-onset GHD [FDA Label].
DB11653BremelanotideBremelanotide is indicated to treat premenopausal women with hypoactive sexual desire disorder that is not due to a medical or psychiatric condition, problems with the relationship, or the effects of a medication or drug.[L4894]
DB11700SetmelanotideNot Available
DB13298AlsactideNot Available
DB14741Luteinizing hormoneNot Available
DB15093SomapacitanNot Available
DB15112Somatropin pegolNot Available
DB15263ThyrotropinNot Available
DB12950AlbusomatropinNot Available
DrugDrug NameTargetType
DB01284TetracosactideAdrenocorticotropic hormone receptortarget
DB01285CorticotropinAdrenocorticotropic hormone receptortarget
DB01285CorticotropinCorticoliberintarget
DB01285Corticotropin3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2enzyme
DB01285Corticotropin25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrialenzyme
DB01285Corticotropin1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrialenzyme
DB01285CorticotropinCytochrome P450 3A4enzyme
DB04931AfamelanotideMelanocyte-stimulating hormone receptortarget
DB00024Thyrotropin alfaThyrotropin receptortarget
DB00032MenotropinsFollicle-stimulating hormone receptortarget
DB00032MenotropinsLutropin-choriogonadotropic hormone receptortarget
DB00052SomatotropinGrowth hormone receptortarget
DB00052SomatotropinProlactin receptortarget
DB00066FollitropinFollicle-stimulating hormone receptortarget
DB00082PegvisomantGrowth hormone receptortarget
DB00082PegvisomantSterol 26-hydroxylase, mitochondrialenzyme
DB00082PegvisomantGlutamine synthetaseenzyme
DB00082PegvisomantCytochrome P450 2C18enzyme
DB00082PegvisomantCytochrome P450 3A4enzyme
DB00082PegvisomantCholinesteraseenzyme
DB00082PegvisomantCytochrome P450 2C19enzyme
DB00082PegvisomantCytochrome P450 4A11enzyme
DB00094UrofollitropinFollicle-stimulating hormone receptortarget
DB09066Corifollitropin alfaFollicle-stimulating hormone receptortarget
DB09098SomatremGrowth hormone receptortarget
DB09098SomatremInsulin-like growth factor 1 receptortarget
DB11653BremelanotideMelanocyte-stimulating hormone receptortarget
DB11653BremelanotideMelanocortin receptor 4target
DB11653BremelanotideMelanocortin receptor 3target
DB11653BremelanotideMelanocortin receptor 5target
DB11653BremelanotideAdrenocorticotropic hormone receptortarget