Hemostatics

Name
Hemostatics
Accession Number
DBCAT000115
Description

Agents acting to arrest the flow of blood. Absorbable hemostatics arrest bleeding either by the formation of an artificial clot or by providing a mechanical matrix that facilitates clotting when applied directly to the bleeding surface. These agents function more at the capillary level and are not effective at stemming arterial or venous bleeding under any significant intravascular pressure.

ATC Classification
Drugs
DrugDrug Description
MenadioneThe primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification.
Tranexamic acidAn antifibrinolytic agent used for heavy menstrual bleeding.
Aminocaproic acidAn antifibrinolytic agent used to induce clotting postoperatively.
PhylloquinoneA fat soluble vitamin used to treat hemorrhagic conditions in infants and coumarin overdoses.
AprotininA serine protease inhibitor used to reduce the risk for perioperative blood loss and the need for blood transfusion in high-risk patients during cardiopulmonary bypass for coronary artery bypass graft surgery.
BatroxobinNo approved indications. Batroxobin is a defibrongenating agent which has been observed to reduce fibrinogen levels and thus reduce clot risk when used intravenously.
CarbazochromeIndicated for capillary and parenchymal hemorrhage (trauma, tonsillectomy, during surgery), intestinal bleeding, and thrombocytopenic purpura.
ThrombinA coagulation factor used to stop bleeding during surgery.
EtamsylateNot Annotated
Oxidized celluloseNot Annotated
Calcium alginateNot Annotated
Antihemophilic factor, human recombinantA form of recombinant coagulation Factor VIII used to treat hemophilia A, von Willebrand disease, and Factor XIII deficiency.
Coagulation factor VIIa Recombinant HumanA form of recombinant human coagulation Factor VII used to treat hemophilia A and B.
Coagulation Factor IX (Recombinant)A form of recombinant human coagulation Factor IX used to treat hemophilia B.
Fibrinogen humanA hemostatic agent used for the treatment of acute bleeding episodes in patients with congenital fibrinogen deficiency, including afibrinogenemia and hypofibrinogenemia.
CatridecacogA recombinant FXIII subunitā€A molecule evaluated for clotting factor replacement therapy in congenital FXIII deficiency.
Susoctocog alfaA recombinant Factor VIII used to treat and prevent bleeding in hemophilia A.
Anti-inhibitor coagulant complexA medication used to control bleeding episodes and prevent bleeding episodes in hemophilia A and B.
DesmopressinA synthetic analog of vasopressin used to reduce renal excretion of water in central diabetes insipidus and nocturia.
VasopressinA peptide hormone used to increase blood pressure in patients with vasodilatory shock who are resistant to fluid and catecholamine therapy.
Formic acidFormic acid (systematically called methanoic acid) is the simplest carboxylic acid. It is an important intermediate in chemical synthesis and occurs naturally, most famously in the venom of bee and...
PoliglusamPoliglusam, or chitosan, is a linear polysaccharide consisting of D-glucosamine and N-acetyl-D-glucosamine. Naturally-occuring poliglusam is found in the cell walls of fungi, soil and sediments where it is produced from...
MenatetrenoneMenatetrenone has been used in trials studying the treatment of Diabetes, Osteoporosis, Prediabetic State, and Hepatocellular Carcinoma.
AminaphthoneAminaftone has been investigated for the treatment of Cockett Syndrome, May-Thurner Syndrome, and Iliac Vein Obstruction.
Menaquinone 7Menaquinone 7 is under investigation in clinical trial NCT00402974 (The Effect of Vitamin K Supplementation on Osteocalcin Carboxylation in Healthy Children).
AdrenaloneNot Annotated
OrnipressinNot Annotated
Dobesilic acidNot Annotated
NaftazoneNot Annotated
Ferric subsulfateFerric subsulfate is a stypic or hemostatic agent that causes agglutination of surface proteins resulting in local hemostasis. It has the chemical formula Fe4(OH)2(SO4)5. It is used after superficial skin...
Bismuth subgallateA medication used to deodorize flatulence and stools as well as hemostasis in soft tissue surgery.
Alpha-1-proteinase inhibitorA purified form of human alpha-1 proteinase inhibitor used to treat emphysema patients with associated alpha-1 proteinase inhibitor deficiency.
RomiplostimA fusion protein thrombopoietin (TPO) peptide analog that increases platelet counts by binding to and activating the human TPO receptor. Used to treat thrombocytopenia associated with chronic immune thrombocytopenia (ITP).
EltrombopagA thrombopoietin receptor agonist used to treat thrombocytopenia or aplastic anemia associated with various etiologies.
Von Willebrand Factor HumanA complex of von Willebrand Factor and Factor VIII used to treat bleeding episodes in von Willebrand disease.
Coagulation factor X humanA coagulation factor used to treat Factor X deficiency to control bleeding.
Antihemophilic factor humanA Factor VIII replacement therapy used to treat hemophilia A.
Aminomethylbenzoic acidAminomethylbenzoic acid may be useful as an antifibrinolytic agent .
Tetragalacturonic acid hydroxymethylesterNot Annotated
CamostatNot Annotated
Turoctocog alfaAn antihemorrhagic agent used for the treatment and prophylaxis of bleeding in patients of all ages with haemophilia A (congenital factor VIII deficiency).
Antihemophilic Factor (Recombinant), PEGylatedFor the management of hemophilia A (congenital factor VIII deficiency) [FDA label], . This medication is a human antihemophilic factor indicated in adolescent and adult patients (12 years and older)...
Thrombin alfaA platelet activating factor used to treat minor bleeding.
Efmoroctocog alfaA recombinant Factor VIII used to treat and prevent bleeding in hemophilia A.
Eftrenonacog alfaA recombinant Factor IX used to treat and prevent bleeding in hemophilia B.
Factor XIII (human)A purified form of Factor XIII that is used to prevent and treat surgical bleeding in patients with a Factor XIII deficiency.
Coagulation Factor IX HumanA coagulation factor used to treat hemophilia B or factor IX hemophilia.
Albutrepenonacog alfaA recombinant Factor IX fused to recombinant human albumin used to treat hemophilia B.
Nonacog beta pegolA recombinant coagulation Factor IX derivative used to treat hemophilia B.
Plasma protein fraction (human)A plasma protein solution used to treat coagulation factor deficiencies, reverse anticoagulant effects, and shock from a loss of plasma fluids, and is also used in plasma exchange procedures.
Lonoctocog alfaA recombinant Factor VIII used to treat hemophilia A to control bleeding.
Moroctocog alfaA recombinant Factor VIII used to treat hemophilia A to control bleeding.
EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
Potassium triiodideNot Annotated
LypressinNot Annotated
Turoctocog alfa pegolTuroctocog alfa pegol (N8-GP) is indicated for use in adults and children of all ages with hemophilia A (congenital factor VIII deficiency) for routine prophylaxis in reducing the frequency of...
AvatrombopagA thrombopoietin receptor agonist used to treat thrombocytopenia in patients with chronic liver disease who are scheduled to undergo a procedure.
FostamatinibA spleen tyrosine kinase inhibitor used to treat chronic immune thrombocytopenia after attempting one other treatment.
LusutrombopagA medication used to treat thrombocytopenia in patients with chronic liver disease scheduled to have a procedure.
EmicizumabAn antibody against Factor IXa and Factor X used to treat hemophilia A.
Menaquinone 6Menaquinone 6 is under investigation in clinical trial NCT01194778 (Comparison of Efficacy of Different Dosages Vitamin K2).
MenaquinoneMenaquinone is under investigation in clinical trial NCT01533441 (Vitamin K2 Intervention in Patients With Vitamin K Antagonists).
Drugs & Drug Targets
DrugTargetType
MenadioneVitamin K-dependent protein Ztarget
MenadioneProthrombintarget
MenadioneVitamin K epoxide reductase complex subunit 1target
MenadioneCoagulation factor IXtarget
MenadioneCoagulation factor VIItarget
MenadioneCoagulation factor Xtarget
MenadioneVitamin K-dependent gamma-carboxylasetarget
MenadioneVitamin K-dependent protein Ctarget
MenadioneVitamin K-dependent protein Starget
MenadioneNAD(P)H dehydrogenase [quinone] 1target
MenadioneRibosyldihydronicotinamide dehydrogenase [quinone]target
MenadioneVitamin K epoxide reductase complex subunit 1-like protein 1target
MenadioneXanthine dehydrogenase/oxidaseenzyme
MenadioneAldehyde oxidaseenzyme
MenadioneMethylenetetrahydrofolate reductaseenzyme
MenadioneCytochrome P450 1A1enzyme
MenadioneOsteocalcintarget
MenadioneCytochrome P450 1A2enzyme
MenadioneCytochrome P450 2A6enzyme
Tranexamic acidPlasminogentarget
Tranexamic acidSolute carrier family 15 member 2transporter
Aminocaproic acidPlasminogentarget
Aminocaproic acidTissue-type plasminogen activatortarget
Aminocaproic acidApolipoprotein(a)target
Aminocaproic acidAldehyde oxidaseenzyme
PhylloquinoneVitamin K-dependent gamma-carboxylasetarget
PhylloquinoneOsteocalcintarget
AprotininTrypsin-1target
AprotininChymotrypsinogen Btarget
AprotininPlasminogentarget
AprotininKallikrein-1target
AprotininCholinesteraseenzyme
ThrombinProteinase-activated receptor 1target
ThrombinProteinase-activated receptor 4target
ThrombinCoagulation factor XItarget
ThrombinCoagulation factor XIII A chaintarget
ThrombinCoagulation factor XIII B chaintarget
ThrombinFibrinogen alpha chaintarget
ThrombinFibrinogen beta chaintarget
ThrombinFibrinogen gamma chaintarget
ThrombinCoagulation factor Vtarget
ThrombinCoagulation factor VIIItarget
Antihemophilic factor, human recombinantCoagulation factor Xtarget
Antihemophilic factor, human recombinantPhytanoyl-CoA dioxygenase, peroxisomaltarget
Antihemophilic factor, human recombinantCoagulation factor IXtarget
Antihemophilic factor, human recombinantAsialoglycoprotein receptor 2target
Antihemophilic factor, human recombinant78 kDa glucose-regulated proteintarget
Antihemophilic factor, human recombinantCalreticulintarget
Antihemophilic factor, human recombinantCalnexintarget
Antihemophilic factor, human recombinantProtein ERGIC-53target
Antihemophilic factor, human recombinantProlow-density lipoprotein receptor-related protein 1target
Antihemophilic factor, human recombinantMultiple coagulation factor deficiency protein 2target
Antihemophilic factor, human recombinantvon Willebrand factortarget
Antihemophilic factor, human recombinantProthrombinenzyme
Antihemophilic factor, human recombinantVitamin K-dependent protein Cenzyme
Coagulation factor VIIa Recombinant HumanCoagulation factor Xtarget
Coagulation factor VIIa Recombinant HumanTissue factortarget
Coagulation factor VIIa Recombinant HumanSerine protease hepsintarget
Coagulation factor VIIa Recombinant HumanTissue factor pathway inhibitortarget
Coagulation factor VIIa Recombinant HumanVitamin K-dependent gamma-carboxylasetarget
Coagulation factor VIIa Recombinant HumanCoagulation factor VIItarget
Coagulation Factor IX (Recombinant)Coagulation factor Xtarget
Coagulation Factor IX (Recombinant)Coagulation factor XItarget
Coagulation Factor IX (Recombinant)Coagulation factor VIIItarget
Coagulation Factor IX (Recombinant)Prothrombintarget
Coagulation Factor IX (Recombinant)Coagulation factor VIItarget
Coagulation Factor IX (Recombinant)Vitamin K-dependent gamma-carboxylasetarget
Coagulation Factor IX (Recombinant)Prolow-density lipoprotein receptor-related protein 1target
CatridecacogCoagulation factor XIII B chaintarget
Susoctocog alfavon Willebrand factortarget
Anti-inhibitor coagulant complexCoagulation factor Xtarget
Anti-inhibitor coagulant complexProthrombintarget
Anti-inhibitor coagulant complexFibrinogen alpha chaintarget
Anti-inhibitor coagulant complexFibrinogen beta chaintarget
Anti-inhibitor coagulant complexCoagulation factor XIII A chaintarget
Anti-inhibitor coagulant complexCoagulation factor Vtarget
Anti-inhibitor coagulant complexCoagulation factor VIIItarget
Anti-inhibitor coagulant complexCoagulation factor VIItarget
Anti-inhibitor coagulant complexProthrombinenzyme
Anti-inhibitor coagulant complexCoagulation factor VIIenzyme
Anti-inhibitor coagulant complexCoagulation factor VIIIenzyme
Anti-inhibitor coagulant complexCoagulation factor IXenzyme
Anti-inhibitor coagulant complexCoagulation factor Venzyme
DesmopressinVasopressin V1a receptortarget
DesmopressinVasopressin V1b receptortarget
DesmopressinVasopressin V2 receptortarget
DesmopressinProstaglandin G/H synthase 1enzyme
DesmopressinProstaglandin G/H synthase 2enzyme
VasopressinVasopressin V1a receptortarget
VasopressinVasopressin V2 receptortarget
VasopressinVasopressin V1b receptortarget
VasopressinCanalicular multispecific organic anion transporter 1transporter
Formic acidPutative hydroxypyruvate isomerase YgbMtarget
Formic acidDelta-aminolevulinic acid dehydratasetarget
Formic acid3-phosphoshikimate 1-carboxyvinyltransferasetarget
Formic acidSubtilisin Carlsbergtarget
Formic acidFibroblast growth factor 1target
Formic acidPeptide deformylasetarget
Formic acidPara-aminobenzoate synthase component 1target
Formic acidCarbonic anhydrase 2target
Formic acidHeme oxygenase 1target
Formic acidRibonuclease pancreatictarget
Formic acidDihydroorotate dehydrogenase (quinone)target
Formic acid(S)-2-haloacid dehalogenasetarget
Formic acidBeta-lactamase OXA-2target
Formic acidCatalasetarget
Formic acidSignal recognition particle proteintarget
Formic acidStreptavidintarget
Formic acidMethylglyoxal synthasetarget
Formic acidC-terminal-binding protein 1target
Formic acid6-phosphogluconolactonasetarget
Formic acidCitrate lyase subunit beta-like proteintarget
Formic acidPeripheral plasma membrane protein CASKtarget
Formic acidGuanylate kinasetarget
Formic acidProbable butyrate kinase 2target
Formic acidGamma-glutamylaminecyclotransferasetarget
Formic acidParvalbumin alphatarget
Formic acidAcylphosphatase-2target
Formic acidUncharacterized proteintarget
Formic acidArginine N-succinyltransferase subunit alphatarget
Formic acidPutative mannose-6-phosphate isomerase YvyItarget
Formic acidNitric oxide synthase, braintarget
Formic acidABC-type transporter, periplasmic subunittarget
Formic acidProbable phosphatase YcdXtarget
Formic acidPhenazine biosynthesis protein PhzDtarget
Formic acidOxalate decarboxylase OxdCtarget
Formic acidPutative ketoacyl reductasetarget
Formic acidGephyrintarget
Formic acidGlyoxalase family proteintarget
Formic acidCytohesin-2target
Formic acidGlutaconyl-CoA decarboxylase subunit alphatarget
Formic acidTranscriptional regulator, IclR familytarget
Formic acidCatalasetarget
Formic acidPutative L-rhamnose mutarotasetarget
Formic acidGlutathione S-transferasetarget
Formic acidHypoxanthine-guanine phosphoribosyltransferasetarget
Formic acidGlutaminase 1target
Formic acidGlutaminase 1target
Formic acidMolybdopterin synthase catalytic subunittarget
Formic acidAminotransferase, putativetarget
Formic acidIron binding protein FbpAtarget
Formic acidDNA gyrase subunit Btarget
Formic acidMonocarboxylate transporter 4transporter
Bismuth subgallateSerum albumincarrier
Alpha-1-proteinase inhibitorNeutrophil elastasetarget
RomiplostimThrombopoietin receptortarget
EltrombopagThrombopoietin receptortarget
EltrombopagCytochrome P450 2C8enzyme
EltrombopagCytochrome P450 1A2enzyme
EltrombopagUDP-glucuronosyltransferase 1-1enzyme
EltrombopagUDP-glucuronosyltransferase 1-3enzyme
EltrombopagSolute carrier organic anion transporter family member 1B1transporter
EltrombopagATP-binding cassette sub-family G member 2transporter
EltrombopagUDP-glucuronosyltransferase 1-9enzyme
Von Willebrand Factor HumanCoagulation factor VIIItarget
Von Willebrand Factor HumanCollagen alpha-1(I) chaintarget
Von Willebrand Factor HumanA disintegrin and metalloproteinase with thrombospondin motifs 13enzyme
Antihemophilic factor humanCoagulation factor IXtarget
Antihemophilic factor humanCoagulation factor Xtarget
Antihemophilic factor humanVitamin K-dependent protein Cenzyme
Turoctocog alfaCoagulation factor IXtarget
Turoctocog alfaCoagulation factor Xtarget
Turoctocog alfaProthrombintarget
Antihemophilic Factor (Recombinant), PEGylatedvon Willebrand factortarget
Antihemophilic Factor (Recombinant), PEGylatedvon Willebrand factorcarrier
Thrombin alfaCoagulation factor XItarget
Thrombin alfaCoagulation factor VIIItarget
Thrombin alfaCoagulation factor Vtarget
Thrombin alfaCoagulation factor XIII A chaintarget
Thrombin alfaCoagulation factor XIII B chaintarget
Thrombin alfaFibrinogen alpha chaintarget
Thrombin alfaFibrinogen beta chaintarget
Thrombin alfaFibrinogen gamma chaintarget
Efmoroctocog alfavon Willebrand factortarget
Coagulation Factor IX HumanCoagulation factor Xtarget
Coagulation Factor IX HumanCoagulation factor XItarget
Coagulation Factor IX HumanCoagulation factor VIItarget
Coagulation Factor IX HumanCoagulation factor VIIItarget
Coagulation Factor IX HumanProthrombintarget
Coagulation Factor IX HumanProlow-density lipoprotein receptor-related protein 1target
Coagulation Factor IX HumanVitamin K-dependent gamma-carboxylasetarget
Albutrepenonacog alfaCoagulation factor Xtarget
Albutrepenonacog alfaCoagulation factor VIIIenzyme
Nonacog beta pegolCoagulation factor VIItarget
Nonacog beta pegolCoagulation factor VIIItarget
Nonacog beta pegolCoagulation factor Xtarget
Lonoctocog alfaCoagulation factor Xtarget
Lonoctocog alfaPhytanoyl-CoA dioxygenase, peroxisomaltarget
Lonoctocog alfaCoagulation factor IXtarget
Lonoctocog alfaAsialoglycoprotein receptor 2target
Lonoctocog alfa78 kDa glucose-regulated proteintarget
Lonoctocog alfaCalreticulintarget
Lonoctocog alfaCalnexintarget
Lonoctocog alfaProtein ERGIC-53target
Lonoctocog alfaProlow-density lipoprotein receptor-related protein 1target
Lonoctocog alfaMultiple coagulation factor deficiency protein 2target
Lonoctocog alfavon Willebrand factortarget
Lonoctocog alfaProthrombinenzyme
Lonoctocog alfaVitamin K-dependent protein Cenzyme
Moroctocog alfaCoagulation factor Xtarget
Moroctocog alfaPhytanoyl-CoA dioxygenase, peroxisomaltarget
Moroctocog alfaCoagulation factor IXtarget
Moroctocog alfaAsialoglycoprotein receptor 2target
Moroctocog alfa78 kDa glucose-regulated proteintarget
Moroctocog alfaCalreticulintarget
Moroctocog alfaCalnexintarget
Moroctocog alfaProtein ERGIC-53target
Moroctocog alfaProlow-density lipoprotein receptor-related protein 1target
Moroctocog alfaMultiple coagulation factor deficiency protein 2target
Moroctocog alfavon Willebrand factortarget
Moroctocog alfaProthrombinenzyme
Moroctocog alfaVitamin K-dependent protein Cenzyme
EpinephrineAlpha-1A adrenergic receptortarget
EpinephrineBeta-1 adrenergic receptortarget
EpinephrineBeta-2 adrenergic receptortarget
EpinephrineSolute carrier family 22 member 2transporter
EpinephrineSolute carrier family 22 member 1transporter
EpinephrineCytochrome P450 2C9enzyme
EpinephrineCytochrome P450 3A4enzyme
EpinephrineAlpha-1B adrenergic receptortarget
EpinephrineAlpha-1D adrenergic receptortarget
EpinephrineAlpha-2A adrenergic receptortarget
EpinephrineAlpha-2B adrenergic receptortarget
EpinephrineTumor necrosis factortarget
EpinephrineCatechol O-methyltransferaseenzyme
EpinephrineMonoamine oxidaseenzyme
LypressinVasopressin V1a receptortarget
LypressinVasopressin V2 receptortarget
LypressinVasopressin V1b receptortarget
LypressinCanalicular multispecific organic anion transporter 1transporter
Turoctocog alfa pegolVitamin K-dependent protein Cenzyme
Turoctocog alfa pegolCoagulation factor Xenzyme
Turoctocog alfa pegolCoagulation factor IXtarget
Turoctocog alfa pegolCoagulation factor Xtarget
Turoctocog alfa pegolProthrombintarget
Turoctocog alfa pegolvon Willebrand factorcarrier
AvatrombopagATP-binding cassette sub-family G member 2target
AvatrombopagCytochrome P450 2C8enzyme
AvatrombopagCytochrome P450 2C9enzyme
AvatrombopagThrombopoietin receptortarget
AvatrombopagP-glycoprotein 1transporter
AvatrombopagSolute carrier family 22 member 8target
FostamatinibAdenosine receptor A3target
Fostamatinibvesicular monoamine transporter 2 (VMAT2)target
FostamatinibFatty-acid amide hydrolase 1target
FostamatinibEquilibrative nucleoside transporter 1target
FostamatinibUDP-glucuronosyltransferase 1-1target
FostamatinibcGMP-specific 3',5'-cyclic phosphodiesterasetarget
FostamatinibArachidonate 5-lipoxygenasetarget
FostamatinibCathepsin Starget
FostamatinibCathepsin L1target
FostamatinibTyrosine-protein kinase ABL1target
FostamatinibCalcium-dependent protein kinase 1target
FostamatinibSerine/threonine-protein kinase PknBtarget
FostamatinibRibosomal protein S6 kinase alpha-6target
FostamatinibNon-receptor tyrosine-protein kinase TYK2target
FostamatinibAtypical kinase COQ8A, mitochondrialtarget
FostamatinibTyrosine-protein kinase JAK1target
FostamatinibHepatocyte growth factor receptortarget
FostamatinibSerine/threonine-protein kinase NIM1target
FostamatinibSerine/threonine-protein kinase MST4target
FostamatinibcAMP-dependent protein kinase catalytic subunit alphatarget
FostamatinibSerine/threonine-protein kinase 24target
FostamatinibSerine/threonine-protein kinase 3target
FostamatinibTyrosine-protein kinase Tectarget
FostamatinibTyrosine-protein kinase SYKtarget
FostamatinibSerine/threonine-protein kinase 33target
FostamatinibSerine/threonine-protein kinase 35target
FostamatinibSerine/threonine-protein kinase 36target
FostamatinibSerine/threonine-protein kinase 38target
FostamatinibSerine/threonine-protein kinase 38-liketarget
FostamatinibSTE20/SPS1-related proline-alanine-rich protein kinasetarget
FostamatinibSerine/threonine-protein kinase TAO1target
FostamatinibSerine/threonine-protein kinase TAO2target
FostamatinibSerine/threonine-protein kinase TAO3target
FostamatinibSerine/threonine-protein kinase TBK1target
FostamatinibAngiopoietin-1 receptortarget
FostamatinibDual specificity testis-specific protein kinase 1target
FostamatinibTGF-beta receptor type-1target
FostamatinibTGF-beta receptor type-2target
FostamatinibTyrosine-protein kinase receptor Tie-1target
FostamatinibSerine/threonine-protein kinase tousled-like 1target
FostamatinibSerine/threonine-protein kinase tousled-like 2target
FostamatinibTRAF2 and NCK-interacting protein kinasetarget
FostamatinibNon-receptor tyrosine-protein kinase TNK1target
FostamatinibActivated CDC42 kinase 1target
FostamatinibSerine/threonine-protein kinase TNNI3Ktarget
FostamatinibTestis-specific serine/threonine-protein kinase 1target
FostamatinibDual specificity protein kinase TTKtarget
FostamatinibTyrosine-protein kinase TXKtarget
FostamatinibTyrosine-protein kinase receptor TYRO3target
FostamatinibSerine/threonine-protein kinase ULK1target
FostamatinibSerine/threonine-protein kinase ULK2target
FostamatinibSerine/threonine-protein kinase ULK3target
FostamatinibWee1-like protein kinasetarget
FostamatinibTyrosine-protein kinase Yestarget
FostamatinibMitogen-activated protein kinase kinase kinase 19target
FostamatinibMitogen-activated protein kinase kinase kinase MLTtarget
FostamatinibTyrosine-protein kinase ZAP-70target
FostamatinibAP2-associated protein kinase 1target
FostamatinibAbelson tyrosine-protein kinase 2target
FostamatinibActivin receptor type-1target
FostamatinibActivin receptor type-1Btarget
FostamatinibAtypical kinase COQ8B, mitochondrialtarget
FostamatinibALK tyrosine kinase receptortarget
FostamatinibAnkyrin repeat and protein kinase domain-containing protein 1target
FostamatinibAurora kinase Atarget
FostamatinibAurora kinase Btarget
FostamatinibAurora kinase Ctarget
FostamatinibTyrosine-protein kinase receptor UFOtarget
FostamatinibTyrosine-protein kinase Blktarget
FostamatinibBMP-2-inducible protein kinasetarget
FostamatinibBone morphogenetic protein receptor type-1Btarget
FostamatinibBone morphogenetic protein receptor type-2target
FostamatinibCytoplasmic tyrosine-protein kinase BMXtarget
FostamatinibSerine/threonine-protein kinase B-raftarget
FostamatinibTyrosine-protein kinase BTKtarget
FostamatinibCalcium/calmodulin-dependent protein kinase type 1target
FostamatinibCalcium/calmodulin-dependent protein kinase type 1Dtarget
FostamatinibCalcium/calmodulin-dependent protein kinase type 1Gtarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit alphatarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit betatarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit deltatarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit gammatarget
FostamatinibCalcium/calmodulin-dependent protein kinase kinase 1target
FostamatinibCalcium/calmodulin-dependent protein kinase kinase 2target
FostamatinibPeripheral plasma membrane protein CASKtarget
FostamatinibKappa-caseintarget
FostamatinibCyclin-dependent kinase 1target
FostamatinibSerine/threonine-protein kinase MRCK gammatarget
FostamatinibCyclin-dependent kinase 4target
FostamatinibCyclin-dependent kinase-like 1target
FostamatinibCyclin-dependent kinase-like 2target
FostamatinibSerine/threonine-protein kinase Chk1target
FostamatinibSerine/threonine-protein kinase Chk2target
FostamatinibCitron Rho-interacting kinasetarget
FostamatinibDual specificity protein kinase CLK1target
FostamatinibDual specificity protein kinase CLK2target
FostamatinibDual specificity protein kinase CLK3target
FostamatinibDual specificity protein kinase CLK4target
FostamatinibMacrophage colony-stimulating factor 1 receptortarget
FostamatinibTyrosine-protein kinase CSKtarget
FostamatinibCasein kinase I isoform alphatarget
FostamatinibCasein kinase II subunit alphatarget
FostamatinibCasein kinase II subunit alpha'target
FostamatinibDeath-associated protein kinase 1target
FostamatinibDeath-associated protein kinase 2target
FostamatinibDeath-associated protein kinase 3target
FostamatinibSerine/threonine-protein kinase DCLK1target
FostamatinibSerine/threonine-protein kinase DCLK2target
FostamatinibSerine/threonine-protein kinase DCLK3target
FostamatinibEpithelial discoidin domain-containing receptor 1target
FostamatinibDiscoidin domain-containing receptor 2target
FostamatinibDual specificity tyrosine-phosphorylation-regulated kinase 1Atarget
FostamatinibDual specificity tyrosine-phosphorylation-regulated kinase 1Btarget
FostamatinibEpidermal growth factor receptortarget
FostamatinibEukaryotic translation initiation factor 2-alpha kinase 1target
FostamatinibInterferon-induced, double-stranded RNA-activated protein kinasetarget
FostamatinibeIF-2-alpha kinase GCN2target
FostamatinibEphrin type-A receptor 1target
FostamatinibEphrin type-A receptor 2target
FostamatinibEphrin type-A receptor 3target
FostamatinibEphrin type-A receptor 4target
FostamatinibEphrin type-A receptor 5target
FostamatinibEphrin type-A receptor 6target
FostamatinibEphrin type-A receptor 7target
FostamatinibEphrin type-A receptor 8target
FostamatinibEphrin type-B receptor 1target
FostamatinibEphrin type-B receptor 2target
FostamatinibEphrin type-B receptor 4target
FostamatinibEphrin type-B receptor 6target
FostamatinibReceptor tyrosine-protein kinase erbB-2target
FostamatinibReceptor tyrosine-protein kinase erbB-4target
FostamatinibSerine/threonine-protein kinase/endoribonuclease IRE1target
FostamatinibTyrosine-protein kinase Fertarget
FostamatinibTyrosine-protein kinase Fes/Fpstarget
FostamatinibFibroblast growth factor receptor 1target
FostamatinibFibroblast growth factor receptor 2target
FostamatinibFibroblast growth factor receptor 3target
FostamatinibTyrosine-protein kinase Fgrtarget
FostamatinibVascular endothelial growth factor receptor 1target
FostamatinibReceptor-type tyrosine-protein kinase FLT3target
FostamatinibVascular endothelial growth factor receptor 3target
FostamatinibSerine/threonine-protein kinase mTORtarget
FostamatinibTyrosine-protein kinase FRKtarget
FostamatinibTyrosine-protein kinase Fyntarget
FostamatinibCyclin-G-associated kinasetarget
FostamatinibGlycogen synthase kinase-3 alphatarget
FostamatinibGlycogen synthase kinase-3 betatarget
FostamatinibTyrosine-protein kinase HCKtarget
FostamatinibHomeodomain-interacting protein kinase 2target
FostamatinibHomeodomain-interacting protein kinase 3target
FostamatinibSerine/threonine-protein kinase ICKtarget
FostamatinibInhibitor of nuclear factor kappa-B kinase subunit betatarget
FostamatinibInhibitor of nuclear factor kappa-B kinase subunit epsilontarget
FostamatinibInsulin receptortarget
FostamatinibInsulin receptor-related proteintarget
FostamatinibInterleukin-1 receptor-associated kinase 1target
FostamatinibInterleukin-1 receptor-associated kinase 3target
FostamatinibInterleukin-1 receptor-associated kinase 4target
FostamatinibTyrosine-protein kinase ITK/TSKtarget
FostamatinibTyrosine-protein kinase JAK2target
FostamatinibTyrosine-protein kinase JAK3target
FostamatinibVascular endothelial growth factor receptor 2target
FostamatinibSerine/threonine-protein kinase SIK3target
FostamatinibMast/stem cell growth factor receptor Kittarget
FostamatinibSerine/threonine-protein kinase LATS1target
FostamatinibTyrosine-protein kinase Lcktarget
FostamatinibLIM domain kinase 1target
FostamatinibLIM domain kinase 2target
FostamatinibLeucine-rich repeat serine/threonine-protein kinase 2target
FostamatinibLeukocyte tyrosine kinase receptortarget
FostamatinibTyrosine-protein kinase Lyntarget
FostamatinibDual specificity mitogen-activated protein kinase kinase 2target
FostamatinibDual specificity mitogen-activated protein kinase kinase 3target
FostamatinibDual specificity mitogen-activated protein kinase kinase 5target
FostamatinibDual specificity mitogen-activated protein kinase kinase 6target
FostamatinibMitogen-activated protein kinase kinase kinase 1target
FostamatinibMitogen-activated protein kinase kinase kinase 10target
FostamatinibMitogen-activated protein kinase kinase kinase 11target
FostamatinibMitogen-activated protein kinase kinase kinase 12target
FostamatinibMitogen-activated protein kinase kinase kinase 13target
FostamatinibMitogen-activated protein kinase kinase kinase 15target
FostamatinibMitogen-activated protein kinase kinase kinase 2target
FostamatinibMitogen-activated protein kinase kinase kinase 3target
FostamatinibMitogen-activated protein kinase kinase kinase 4target
FostamatinibMitogen-activated protein kinase kinase kinase 6target
FostamatinibMitogen-activated protein kinase kinase kinase 9target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 1target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 2target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 3target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 4target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 5target
FostamatinibMitogen-activated protein kinase 10target
FostamatinibMitogen-activated protein kinase 13target
FostamatinibMitogen-activated protein kinase 14target
FostamatinibMitogen-activated protein kinase 15target
FostamatinibMitogen-activated protein kinase 4target
FostamatinibMitogen-activated protein kinase 7target
FostamatinibMitogen-activated protein kinase 9target
FostamatinibMAP kinase-activated protein kinase 5target
FostamatinibSerine/threonine-protein kinase MARK1target
FostamatinibSerine/threonine-protein kinase MARK2target
FostamatinibMAP/microtubule affinity-regulating kinase 3target
FostamatinibMAP/microtubule affinity-regulating kinase 4target
FostamatinibCLIP-associating protein 1target
FostamatinibMicrotubule-associated serine/threonine-protein kinase 1target
FostamatinibMegakaryocyte-associated tyrosine-protein kinasetarget
FostamatinibMaternal embryonic leucine zipper kinasetarget
FostamatinibTyrosine-protein kinase Mertarget
FostamatinibMisshapen-like kinase 1target
FostamatinibMAP kinase-interacting serine/threonine-protein kinase 1target
FostamatinibMAP kinase-interacting serine/threonine-protein kinase 2target
FostamatinibMacrophage-stimulating protein receptortarget
FostamatinibMuscle, skeletal receptor tyrosine-protein kinasetarget
FostamatinibMyosin light chain kinase, smooth muscletarget
FostamatinibMyosin light chain kinase 2, skeletal/cardiac muscletarget
FostamatinibMyosin light chain kinase 3target
FostamatinibMyosin light chain kinase family member 4target
FostamatinibMyosin-IIIatarget
FostamatinibSerine/threonine-protein kinase Nek1target
FostamatinibSerine/threonine-protein kinase Nek11target
FostamatinibSerine/threonine-protein kinase Nek2target
FostamatinibSerine/threonine-protein kinase Nek3target
FostamatinibSerine/threonine-protein kinase Nek4target
FostamatinibSerine/threonine-protein kinase Nek5target
FostamatinibSerine/threonine-protein kinase Nek9target
FostamatinibHigh affinity nerve growth factor receptortarget
FostamatinibBDNF/NT-3 growth factors receptortarget
FostamatinibNT-3 growth factor receptortarget
FostamatinibNUAK family SNF1-like kinase 1target
FostamatinibNUAK family SNF1-like kinase 2target
FostamatinibSerine/threonine-protein kinase OSR1target
FostamatinibSerine/threonine-protein kinase PAK 1target
FostamatinibSerine/threonine-protein kinase PAK 2target
FostamatinibSerine/threonine-protein kinase PAK 3target
FostamatinibSerine/threonine-protein kinase PAK 4target
FostamatinibSerine/threonine-protein kinase PAK 6target
FostamatinibSerine/threonine-protein kinase PAK 5target
FostamatinibCyclin-dependent kinase 16target
FostamatinibCyclin-dependent kinase 17target
FostamatinibPlatelet-derived growth factor receptor alphatarget
FostamatinibPlatelet-derived growth factor receptor betatarget
Fostamatinib3-phosphoinositide-dependent protein kinase 1target
FostamatinibCyclin-dependent kinase 15target
FostamatinibPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoformtarget
FostamatinibPhosphatidylinositol 4-kinase betatarget
FostamatinibPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betatarget
FostamatinibPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gammatarget
FostamatinibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
FostamatinibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
FostamatinibSerine/threonine-protein kinase pim-1target
FostamatinibSerine/threonine-protein kinase pim-3target
FostamatinibPhosphatidylinositol 5-phosphate 4-kinase type-2 betatarget
FostamatinibPhosphatidylinositol 5-phosphate 4-kinase type-2 gammatarget
FostamatinibMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinasetarget
FostamatinibSerine/threonine-protein kinase N1target
FostamatinibSerine/threonine-protein kinase N2target
FostamatinibSerine/threonine-protein kinase PLK1target
FostamatinibSerine/threonine-protein kinase PLK2target
FostamatinibSerine/threonine-protein kinase PLK3target
FostamatinibSerine/threonine-protein kinase PLK4target
Fostamatinib5'-AMP-activated protein kinase catalytic subunit alpha-1target
Fostamatinib5'-AMP-activated protein kinasetarget
FostamatinibcAMP-dependent protein kinase catalytic subunit betatarget
FostamatinibProtein kinase C delta typetarget
FostamatinibProtein kinase C epsilon typetarget
FostamatinibProtein kinase C gamma type (PRKCG)target
FostamatinibProtein kinase C iota typetarget
FostamatinibProtein kinase C theta typetarget
FostamatinibSerine/threonine-protein kinase D1target
FostamatinibcGMP-dependent protein kinase 2target
FostamatinibSerine/threonine-protein kinase PRP4 homologtarget
FostamatinibFocal adhesion kinase 1target
FostamatinibProtein-tyrosine kinase 2-betatarget
FostamatinibProtein-tyrosine kinase 6target
FostamatinibRAF proto-oncogene serine/threonine-protein kinasetarget
FostamatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
FostamatinibSerine/threonine-protein kinase RIO1target
FostamatinibSerine/threonine-protein kinase RIO2target
FostamatinibSerine/threonine-protein kinase RIO3target
FostamatinibReceptor-interacting serine/threonine-protein kinase 1target
FostamatinibReceptor-interacting serine/threonine-protein kinase 2target
FostamatinibReceptor-interacting serine/threonine-protein kinase 4target
FostamatinibRho-associated protein kinase 2target
FostamatinibProto-oncogene tyrosine-protein kinase ROStarget
FostamatinibRibosomal protein S6 kinase alpha-1target
FostamatinibRibosomal protein S6 kinase alpha-3target
FostamatinibSerine/threonine-protein kinase SBK1target
FostamatinibUncharacterized serine/threonine-protein kinase SBK3target
FostamatinibSerine/threonine-protein kinase Sgk3target
FostamatinibSerine/threonine-protein kinase SIK1target
FostamatinibSerine/threonine-protein kinase SIK2target
FostamatinibSTE20-like serine/threonine-protein kinasetarget
FostamatinibSNF-related serine/threonine-protein kinasetarget
FostamatinibProto-oncogene tyrosine-protein kinase Srctarget
FostamatinibTyrosine-protein kinase Srmstarget
FostamatinibSerine/threonine-protein kinase 10target
FostamatinibSerine/threonine-protein kinase 16target
FostamatinibSerine/threonine-protein kinase 17Atarget
FostamatinibSerine/threonine-protein kinase 17Btarget
FostamatinibSerine/threonine-protein kinase 32Atarget
FostamatinibCytochrome P450 3A4enzyme
FostamatinibATP-binding cassette sub-family G member 2transporter
FostamatinibATP-binding cassette sub-family B member 5transporter
FostamatinibUDP-glucuronosyltransferase 1-9enzyme
LusutrombopagCytochrome P450 4A11enzyme
LusutrombopagP-glycoprotein 1transporter
LusutrombopagATP-binding cassette sub-family G member 2transporter
LusutrombopagThrombopoietin receptortarget
EmicizumabCoagulation factor IXtarget
EmicizumabCoagulation factor Xtarget