Carbon-Oxygen Lyases

Name
Carbon-Oxygen Lyases
Accession Number
DBCAT000168
Description

Enzymes that catalyze the cleavage of a carbon-oxygen bond by means other than hydrolysis or oxidation. EC 4.2.

Drugs
DrugDrug Description
HyaluronidaseAn enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents.
Hyaluronidase (human recombinant)An enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents.
Elosulfase alfaA lysosomal glycosaminoglycan (GAG)-specific enzyme indicated as an enzyme replacement therapy for Mucopolysaccharidosis type IV A.
Pegvorhyaluronidase alfaPegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection).
Drugs & Drug Targets
DrugTargetType
HyaluronidaseHyaluronic acidtarget
HyaluronidaseTransforming growth factor beta-1target
Hyaluronidase (human recombinant)Hyaluronic acidtarget
Hyaluronidase (human recombinant)Transforming growth factor beta-1target