Lyases
- Name
- Lyases
- Accession Number
- DBCAT000169
- Description
A class of enzymes that catalyze the cleavage of C-C, C-O, and C-N, and other bonds by other means than by hydrolysis or oxidation. (Enzyme Nomenclature, 1992) EC 4.
- Drugs
Drug Drug Description Hyaluronidase An enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. Pegvaliase An enzyme used to treat phenylketonuria in patients with phenylalanine levels that are too high on current treatment. Hyaluronidase (human recombinant) An enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. Elosulfase alfa A lysosomal glycosaminoglycan (GAG)-specific enzyme indicated as an enzyme replacement therapy for Mucopolysaccharidosis type IV A. Pegvorhyaluronidase alfa Pegvorhyaluronidase alfa is under investigation in clinical trial NCT02241187 (Two Stage Study Of Single Dose PEGPH20 And Cetuximab In Patients With Pancreatic Adenocarcinoma Prior To Surgical Resection). Reloxaliase Reloxaliase is a crystalline formulation of oxalate decarboxylase derived from Bacillus Subtilis. Reloxaliase is under investigation in clinical trial NCT03456830 (Evaluate ALLN-177 in Patients With Enteric Hyperoxaluria). - Drugs & Drug Targets