Keto Acids

DrugDrug NameDrug Indication
DB00119Pyruvic acidFor nutritional supplementation, also for treating dietary shortage or imbalance
DB00345Aminohippuric acidUsed to measure effective renal plasma flow (ERPF) and to determine the functional capacity of the tubular excretory mechanism.
DB00855Aminolevulinic acidAminolevulinic acid plus blue light illumination using a blue light photodynamic therapy illuminator is indicated for the treatment of minimally to moderately thick actinic keratoses of the face or scalp.
DB00992Methyl aminolevulinateFor topical use, in combination with 570 to 670 nm wavelength red light illumination, in the treatment of non-hyperkeratotic actinic keratoses of the face and scalp in immunocompetent patients when used in conjunction with lesion preparation (debridement using a sharp dermal curette).
DB01762Acetoacetic AcidNot Available
DB028285-Fluorolevulinic AcidNot Available
DB029513-Hydroxypyruvic AcidNot Available
DB03578PyruvamideNot Available
DB05869Ethyl pyruvateInvestigated for use/treatment in burns and burn infections, cardiac surgery, inflammatory disorders (unspecified), ischemic reperfusion injury, and sepsis and septicemia.
DB06261HexaminolevulinateHexaminolevulinate is indicated for use in the cystoscopic detection of non-muscle invasive papillary cancer of the bladder among patients suspected or known to have lesion(s) on the basis of a prior cystoscopy.
DB06799MethenamineFor prophylactic or suppressive treatment of frequently recurring urinary tract infections when long-term therapy is considered necessary. This drug is not used to treat infection and should only be used after appropriate eradication of infection with antimicrobial agents.
DB070693-Hydroxyhippuric acidNot Available
DB08845Oxogluric acidα-α-Ketoglutarate is not approved for any indication in the world but is an investigational drug in the United States. The potential indications for α-Ketoglutarate are in patients with the metabolic disorder propionic acidemia and in trauma patients with muscle loss.
DB13800Calcium levulinateThis new application of calcium is intended for use as a food fortifier, to fortify foods like sauces, condiments, beer, beverages, soft drinks, milk and milk products, soy milk and soy products with calcium nutrition [L2765]. Calcium levulinate can be used alone, or with calcium lactate, calcium chloride, and other compounds, either for pharmaceutical tablets, capsules, or injections preparation [L2765]. In essence, calcium levulinate is ultimately a relatively new calcium supplementation option [L2767].
DB14514Magnesium levulinateNot Available
DB03884Phenylpyruvic acidNot Available
DB15445Iodohippuric acidNot Available
DrugDrug NameTargetType
DB00119Pyruvic acidMonocarboxylate transporter 4target
DB00119Pyruvic acidMonocarboxylate transporter 8target
DB00119Pyruvic acidAlanine--glyoxylate aminotransferase 2, mitochondrialtarget
DB00119Pyruvic acidMonocarboxylate transporter 6target
DB00119Pyruvic acidPyruvate kinase PKLRtarget
DB00119Pyruvic acidMonocarboxylate transporter 7target
DB00119Pyruvic acidMonocarboxylate transporter 2target
DB00119Pyruvic acidPyruvate dehydrogenase E1 component subunit beta, mitochondrialtarget
DB00119Pyruvic acidPyruvate kinase PKMtarget
DB00119Pyruvic acid4-aminobutyrate aminotransferase, mitochondrialtarget
DB00119Pyruvic acidMonocarboxylate transporter 5target
DB00119Pyruvic acidMonocarboxylate transporter 3target
DB00119Pyruvic acidMonocarboxylate transporter 1target
DB00119Pyruvic acidPyruvate carboxylase, mitochondrialtarget
DB00119Pyruvic acidMonocarboxylate transporter 2transporter
DB00119Pyruvic acidMonocarboxylate transporter 1transporter
DB00119Pyruvic acidMonocarboxylate transporter 10transporter
DB00119Pyruvic acidSolute carrier organic anion transporter family member 2A1transporter
DB00119Pyruvic acidMonocarboxylate transporter 4transporter
DB00345Aminohippuric acidSolute carrier family 22 member 2transporter
DB00345Aminohippuric acidSolute carrier family 22 member 5transporter
DB00345Aminohippuric acidSolute carrier family 22 member 6transporter
DB00345Aminohippuric acidSolute carrier family 22 member 8transporter
DB00345Aminohippuric acidCanalicular multispecific organic anion transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 4transporter
DB00345Aminohippuric acidSolute carrier family 22 member 11transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 3A1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1B1transporter
DB00345Aminohippuric acidMultidrug resistance-associated protein 1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1A2transporter
DB00345Aminohippuric acidMonocarboxylate transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 7transporter
DB00855Aminolevulinic acidDelta-aminolevulinic acid dehydratasetarget
DB00855Aminolevulinic acidSolute carrier family 15 member 1transporter
DB00855Aminolevulinic acidSolute carrier family 15 member 2transporter
DB00992Methyl aminolevulinateHigh affinity immunoglobulin gamma Fc receptor Itarget
DB01762Acetoacetic AcidFumarylacetoacetasetarget
DB01762Acetoacetic AcidMonocarboxylate transporter 2transporter
DB01762Acetoacetic AcidMonocarboxylate transporter 1transporter
DB01762Acetoacetic AcidMonocarboxylate transporter 4transporter
DB01762Acetoacetic AcidSodium-coupled monocarboxylate transporter 1transporter
DB028285-Fluorolevulinic AcidDelta-aminolevulinic acid dehydratasetarget
DB029513-Hydroxypyruvic AcidTriosephosphate isomerasetarget
DB029513-Hydroxypyruvic AcidN-acetylneuraminate lyasetarget
DB05869Ethyl pyruvateTumor necrosis factortarget
DB05869Ethyl pyruvateHigh mobility group protein B1target
DB070693-Hydroxyhippuric acidKynureninasetarget
DB08845Oxogluric acidAspartate aminotransferasetarget
DB13800Calcium levulinateCalmodulintarget
DB13800Calcium levulinateCalsequestrin-1target
DB13800Calcium levulinateCalretinintarget
DB14514Magnesium levulinateSodium/potassium-transporting ATPase subunit alpha-1target
DB03884Phenylpyruvic acidMonocarboxylate transporter 4transporter
DB03884Phenylpyruvic acidL-phenylalanine dehydrogenasetarget
DB03884Phenylpyruvic acidHydroxyacid oxidase 1target
DB03884Phenylpyruvic acidIndole-3-pyruvate decarboxylasetarget
DB03884Phenylpyruvic acidPutative uncharacterized proteintarget
DB03884Phenylpyruvic acidBacilysin biosynthesis protein BacBtarget
DB03884Phenylpyruvic acidProbable chorismate mutasetarget