Amino Acids, Aromatic

Name
Amino Acids, Aromatic
Accession Number
DBCAT000262
Description

Amino acids containing an aromatic side chain.

Drugs
DrugDrug Description
PhenylalanineAn amino acid commonly found as a component of total parenteral nutrition.
TyrosineAn amino acid commonly found as a component in total parenteral nutrition.
TryptophanAn amino acid commonly found as a component of total parenteral nutrition.
LevothyroxineA synthetic T4 hormone used to treat hypothyroidism that can be used along with surgery and radioiodine therapy to manage thyrotropin-dependent well-differentiated thyroid cancer.
DextrothyroxineA thyroid hormone used to treat hyperlipidemia.
NateglinideA meglitinide used to treat non insulin dependent diabetes mellitus.
MetyrosineA tyrosine 3-monooxygenase inhibitor used to treat excessive sympathetic stimulation in pheochromocytoma.
TirofibanA platelet aggregation inhibitor used to prevent thrombotic events in non-ST elevated acute coronary syndrome.
MethyldopaAn alpha-2 adrenergic agonist used to treat hypertension.
MelphalanAn alkylating antineoplastic agent used to treat multiple myeloma and ovarian carcinoma.
LevodopaA dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism.
LiotrixMay be used to treat primary, secondary or tertiary hypothyroidism. May also be used to suppress thyroid stimulating hormone (TSH) secretion in patients with simple (nontoxic) goiter, subacute or chronic...
OxitriptanFor use as an antidepressant, appetite suppressant, and sleep aid.
N,O-Didansyl-L-TyrosineNot Available
L-tyrosinamideNot Available
3-TyrosineNot Available
4-Iodo-L-phenylalanineNot Available
BatimastatNot Available
PhenylalanylamideNot Available
6-hydroxydopa quinoneNot Available
Paratoulene phosphateNot Available
PhenyldehydroalanineNot Available
CDP323Investigated for use/treatment in multiple sclerosis.
LX1031Irritable bowel syndrome (IBS) and other gastrointestinal disorders
WX-UK1Investigated for use/treatment in solid tumors.
GW-559090Investigated for use/treatment in asthma and allergic rhinitis.
EtilevodopaInvestigated for use/treatment in parkinson's disease.
EluxadolineA mixed mu-opioid receptor agonist used to treat irritable bowel syndrome with diarrhea.
N-acetyltyrosineAn amino acid used in total parenteral nutrition.
LifitegrastA medication used to treat dry eye disease.
Telotristat ethylA tryptophan hydroxylase inhibitor used to treat carcinoid syndrome.
3,5-diiodothyropropionic acidDITPA has been investigated in Congestive Heart Failure.
IndoximodIndoximod has been used in trials studying the treatment of Glioma, Melanoma, Ependymoma, Gliosarcoma, and Lung Cancer, among others.
MacimorelinA medication used to treat adult growth hormone deficiency.
TiropramideTiropramide is under investigation in clinical trial NCT01629212 (Comparison of the Efficacy and Safety of Tiropramide and Octylonium in the Treatment of Irritable Bowel Syndrome).
MelevodopaNot Annotated
NordazepamAn intermediate in the metabolism of DIAZEPAM to OXAZEPAM. It may have actions similar to those of diazepam.
TelotristatA tryptophan hydroxylase inhibitor. Telotristat ethyl (brand name Xermelo) is a prodrug of telotristat.
TiratricolA metabolite of T3 and T4 thyroid hormones; promoted for hyperlipidemia, localized lipodystrophy, and obesity. Tiratricol has been used in trials studying the treatment of Allan-Herndon-Dudley Syndrome.
5-fluorotryptophan5-fluorotryptophan can be used as substrate analogue to study enzyme mechanisms by NMR spectroscopy.
GS-9191GS-9191 is under investigation in clinical trial NCT00499967 (Safety and Effectiveness Study of an Experimental Topical Ointment (GS-9191) for the Treatment of Genital Warts).
Fluorodopa (18F)Fluorodopa F 18 is indicated for use with positron emission tomography (PET) to visualize dopaminergic nerve terminals in the striatum for the evaluation of adult patients with suspected Parkinsonian syndromes...
SolriamfetolSolriamfetol is indicated for treatment of daytime sleepiness associated with obstructive sleep apnea and narcolepsy, but is not a treatment for the underlying airway obstruction in apnea patients[FDA Label][A176534,A176744].
p-Benzoyl-L-phenylalanineNot Available
Tetraiodothyroacetic acidNot Available
3-nitro-L-tyrosineNot Available
TryptophanamideNot Available
methyl L-phenylalaninateNot Available
Drugs & Drug Targets
DrugTargetType
PhenylalanineTyrosine aminotransferasetarget
PhenylalanineLarge neutral amino acids transporter small subunit 2target
PhenylalaninePhenylalanine--tRNA ligase alpha subunittarget
PhenylalaninePhenylalanine-4-hydroxylasetarget
PhenylalaninePhenylalanine--tRNA ligase, mitochondrialtarget
PhenylalaninePhenylalanine--tRNA ligase beta subunittarget
PhenylalanineTyrosine 3-monooxygenasetarget
PhenylalanineMonocarboxylate transporter 10transporter
TyrosineTyrosine 3-monooxygenasetarget
TyrosineTyrosine--tRNA ligase, mitochondrialtarget
TyrosineTyrosine--tRNA ligase, cytoplasmictarget
TyrosineTyrosine aminotransferasetarget
TyrosineMonocarboxylate transporter 8transporter
TyrosineMonocarboxylate transporter 10transporter
TryptophanTryptophan--tRNA ligase, cytoplasmictarget
TryptophanTryptophan--tRNA ligasetarget
TryptophanTryptophan--tRNA ligase, mitochondrialtarget
TryptophanTryptophan 2,3-dioxygenaseenzyme
TryptophanAromatic-L-amino-acid decarboxylaseenzyme
TryptophanMonocarboxylate transporter 8transporter
TryptophanMonocarboxylate transporter 10transporter
TryptophanTryptophan--tRNA ligaseenzyme
TryptophanTryptophan--tRNA ligase, mitochondrialenzyme
TryptophanTryptophan 5-hydroxylase 1enzyme
TryptophanTryptophan 5-hydroxylase 2enzyme
TryptophanTryptophan--tRNA ligase, cytoplasmicenzyme
TryptophanIndoleamine 2,3-dioxygenase 1enzyme
LevothyroxineThyroid hormone receptor alphatarget
LevothyroxineThyroid hormone receptor betatarget
LevothyroxineCytochrome P450 2C8enzyme
LevothyroxineTransthyretincarrier
LevothyroxineSerum albumincarrier
LevothyroxineThyroxine-binding globulincarrier
LevothyroxineP-glycoprotein 1transporter
LevothyroxineMonocarboxylate transporter 8transporter
LevothyroxineSolute carrier organic anion transporter family member 1C1transporter
LevothyroxineSolute carrier organic anion transporter family member 1A2transporter
LevothyroxineSolute carrier organic anion transporter family member 1B1transporter
LevothyroxineSolute carrier organic anion transporter family member 1B3transporter
LevothyroxineSolute carrier organic anion transporter family member 4A1transporter
LevothyroxineSolute carrier organic anion transporter family member 4C1transporter
LevothyroxineLarge neutral amino acids transporter small subunit 1transporter
LevothyroxineUDP-glucuronosyltransferase 1-1enzyme
LevothyroxineSolute carrier organic anion transporter family member 2B1transporter
LevothyroxineIntegrin alpha-Vtarget
LevothyroxineIntegrin beta-3target
LevothyroxineP-glycoprotein 1enzyme
DextrothyroxineThyroid hormone receptor alphatarget
DextrothyroxineThyroid hormone receptor betatarget
DextrothyroxineThyroid peroxidasetarget
DextrothyroxineSolute carrier organic anion transporter family member 1B1transporter
DextrothyroxineSolute carrier organic anion transporter family member 1C1transporter
DextrothyroxineSolute carrier organic anion transporter family member 4A1transporter
DextrothyroxineSolute carrier organic anion transporter family member 4C1transporter
DextrothyroxineLarge neutral amino acids transporter small subunit 1transporter
NateglinideATP-binding cassette sub-family C member 8target
NateglinideCytochrome P450 3A4enzyme
NateglinideCytochrome P450 2C9enzyme
NateglinidePeroxisome proliferator-activated receptor gammatarget
NateglinideCytochrome P450 3A5enzyme
NateglinideCytochrome P450 3A7enzyme
NateglinideSolute carrier family 15 member 1transporter
NateglinideSolute carrier family 15 member 2transporter
NateglinideSolute carrier family 22 member 6transporter
NateglinideMonocarboxylate transporter 1transporter
NateglinideProstaglandin G/H synthase 1enzyme
NateglinideUDP-glucuronosyltransferase 1-9enzyme
NateglinideCytochrome P450 2D6enzyme
NateglinideMultidrug resistance-associated protein 4transporter
NateglinideSerum albumincarrier
NateglinideAlpha-1-acid glycoprotein 1carrier
MetyrosineTyrosine 3-monooxygenasetarget
TirofibanIntegrin alpha-IIbtarget
TirofibanIntegrin beta-3target
MethyldopaAlpha-2A adrenergic receptortarget
MethyldopaCatechol O-methyltransferaseenzyme
MethyldopaSolute carrier family 15 member 1transporter
MethyldopaAromatic-L-amino-acid decarboxylasetarget
MelphalanDNAtarget
MelphalanSolute carrier family 22 member 3transporter
MelphalanLarge neutral amino acids transporter small subunit 1transporter
LevodopaDopamine D1 receptortarget
LevodopaDopamine D2 receptortarget
LevodopaAromatic-L-amino-acid decarboxylaseenzyme
LevodopaSolute carrier family 15 member 1transporter
LevodopaMonocarboxylate transporter 10transporter
LevodopaDopamine D3 receptortarget
LevodopaDopamine D4 receptortarget
LevodopaDopamine D5 receptortarget
LevodopaLarge neutral amino acids transporter small subunit 1transporter
LevodopaLarge neutral amino acids transporter small subunit 2transporter
LevodopaSerum albumincarrier
LiotrixThyroid hormone receptor alphatarget
LiotrixThyroid hormone receptor betatarget
LiotrixCytochrome P450 2C8enzyme
LiotrixSolute carrier organic anion transporter family member 1A2transporter
LiotrixSolute carrier organic anion transporter family member 1B1transporter
LiotrixSolute carrier organic anion transporter family member 1B3transporter
LiotrixSolute carrier organic anion transporter family member 4C1transporter
LiotrixSodium/bile acid cotransportertransporter
LiotrixSolute carrier organic anion transporter family member 1C1transporter
LiotrixSolute carrier organic anion transporter family member 4A1transporter
LiotrixSolute carrier family 22 member 8transporter
LiotrixMonocarboxylate transporter 8transporter
LiotrixMonocarboxylate transporter 10transporter
LiotrixP-glycoprotein 1transporter
LiotrixTransthyretincarrier
LiotrixThyroxine-binding globulincarrier
LiotrixSerum albumincarrier
LiotrixCytochrome P450 3A4enzyme
OxitriptanTryptophan--tRNA ligase 2target
N,O-Didansyl-L-TyrosineThymidylate synthasetarget
L-tyrosinamidePro-neuropeptide Ytarget
L-tyrosinamideValacyclovir hydrolasetarget
3-TyrosineTyrosine 3-monooxygenasetarget
4-Iodo-L-phenylalanineLysozymetarget
4-Iodo-L-phenylalaninePseudomonalisintarget
4-Iodo-L-phenylalanineDipeptidyl peptidase 4target
4-Iodo-L-phenylalanineAminopeptidase Starget
BatimastatNeutrophil collagenasetarget
BatimastatMacrophage metalloelastasetarget
BatimastatMatrix metalloproteinase-16target
BatimastatDisintegrin and metalloproteinase domain-containing protein 28target
BatimastatA disintegrin and metalloproteinase with thrombospondin motifs 5target
PhenylalanylamideGenome polyproteintarget
PhenylalanylamideGenome polyproteintarget
PhenylalanylamideD-Amino acid amidasetarget
6-hydroxydopa quinoneMembrane primary amine oxidasetarget
6-hydroxydopa quinonePrimary amine oxidasetarget
6-hydroxydopa quinonePhenylethylamine oxidasetarget
Paratoulene phosphateProto-oncogene tyrosine-protein kinase Srctarget
CDP323Integrin alpha-4target
LX1031Tryptophan 5-hydroxylase 1target
WX-UK1Urokinase plasminogen activator surface receptortarget
EluxadolineMu-type opioid receptortarget
EluxadolineDelta-type opioid receptortarget
EluxadolineKappa-type opioid receptortarget
EluxadolineSolute carrier organic anion transporter family member 1B1transporter
EluxadolineCanalicular multispecific organic anion transporter 1transporter
EluxadolineSolute carrier family 22 member 8transporter
LifitegrastIntegrin alpha-Ltarget
LifitegrastCytochrome P450 2C9enzyme
LifitegrastSolute carrier organic anion transporter family member 1A2transporter
LifitegrastSolute carrier organic anion transporter family member 2B1transporter
Telotristat ethylTryptophan 5-hydroxylase 2target
Telotristat ethylTryptophan 5-hydroxylase 1target
3,5-diiodothyropropionic acidCytochrome P450 3A4enzyme
MacimorelinGrowth hormone secretagogue receptor type 1target
MacimorelinCytochrome P450 3A4enzyme
NordazepamGABA(A) Receptortarget
NordazepamGABA(A) Receptor Benzodiazepine Binding Sitetarget
TiratricolThyroid hormone receptor betatarget
5-fluorotryptophanTriosephosphate isomerasetarget
5-fluorotryptophanGlutathione S-transferase Mu 1target
Fluorodopa (18F)Aromatic-L-amino-acid decarboxylaseenzyme
SolriamfetolSolute carrier family 22 member 2transporter
SolriamfetolSolute carrier family 22 member 4transporter
SolriamfetolSolute carrier family 22 member 5transporter
SolriamfetolSodium-dependent dopamine transportertarget
SolriamfetolSodium-dependent noradrenaline transportertarget
p-Benzoyl-L-phenylalanineTyrosine-protein phosphatase non-receptor type 1target
p-Benzoyl-L-phenylalanineTyrosine--tRNA ligase, cytoplasmictarget
Tetraiodothyroacetic acidTransthyretincarrier
3-nitro-L-tyrosineGlutathione reductase, mitochondrialtarget
TryptophanamideTryptophan--tRNA ligasetarget
TryptophanamideTryptophan--tRNA ligase, cytoplasmictarget
methyl L-phenylalaninateFimbrial proteintarget
methyl L-phenylalaninateProthrombintarget