Imidazoles

Name
Imidazoles
Accession Number
DBCAT000263
Description

Compounds containing 1,3-diazole, a five membered aromatic ring containing two nitrogen atoms separated by one of the carbons. Chemically reduced ones include IMIDAZOLINES and IMIDAZOLIDINES. Distinguish from 1,2-diazole (PYRAZOLES).

Drugs
DrugDrug Description
BiotinA B-complex vitamin found in many multivitamin products.
PhenytoinAn anticonvulsant drug used in the prophylaxis and control of various types of seizures.
ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
OlmesartanAn angiotensin receptor blocker (ARB) used in the treatment of hypertension.
EtomidateA short-acting intravenous anesthetic indicated for the induction of anesthesia and supplementation of subpotent anesthesia during short operative procedures.
CarbimazoleFor the treatment of hyperthyroidism and thyrotoxicosis. It is also used to prepare patients for thyroidectomy.
CimetidineA histamine H2 receptor antagonist used to manage GERD, peptic ulcer disease, and indigestion.
MephenytoinA phenylhydantoin used to treat refractory partial epilepsy.
ClonidineAn alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines.
DexmedetomidineAn alpha-2 agonist used for sedation during various procedures.
NilutamideAn antineoplastic hormone used to treat prostate cancer.
LosartanAn angiotensin receptor blocker used to treat hypertension and diabetic nephropathy, and is used to reduce the risk of stroke.
PhentolamineAn alpha adrenergic antagonist used to reverse soft tissue anesthesia.
TizanidineAn alpha-2 adrenergic agonist used for the short-term treatment of muscle spasticity.
EthotoinA hydantoin antiepileptic used to control tonic-clonic and complex partial seizures.
MethimazoleA thionamide antithyroid agent that inhibits the actions of thyroid peroxidase, leading to a reduction in thyroid hormone synthesis and amelioration of hyperthyroidism.
TolazolineA vasodilator used to treat pulmonary artery anomalies.
LevamisoleLevamisole is a nicotinic receptor agonist used to treat helminth infections and some skin infections.
DacarbazineAn antineoplastic agent used to treat malignant melanoma and Hodgkin's disease.
TemozolomideAn alkylating agent used to treat glioblastoma multiforme and refractory anaplastic astrocytoma.
VardenafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction.
OndansetronA serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively.
TinidazoleA nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.
MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
OxymetazolineAn alpha-1A adrenoceptor agonist used to treat nasal congestion, allergic reactions of the eye, and facial erythema associated with rosacea.
ApraclonidineAn alpha adrenergic agonist used to treat raised intraocular pressure.
MiconazoleAn antifungal used to treat fungal infections affecting the vagina, mouth and skin.
TrimethaphanFor the controlled reduction of blood pressure during surgery and in the treatment of hypertensive emergencies.
EconazoleA topical antifungal used to treat tinea pedis, tinea cruris, tinea corporis, cutaneous candidiasis and tinea versicolor.
DantroleneA direct-acting skeletal muscle relaxant used for the treatment of management of the fulminant hypermetabolism of skeletal muscle leading to malignant hyperthermia crisis.
FosphenytoinAn antiepileptic agent used for the management of generalized convulsive status epilepticus and prevention and treatment of seizures occurring during neurosurgery.
AICA ribonucleotide5-Aminoimidazole-4-carboxamide ribonucleotide (AICAR) is an intermediate in the generation of inosine monophosphate and analog of adenosine monophosphate (AMP) that is capable of stimulating AMP-dependent protein kinase (AMPK) activity. AICAR has...
trans-urocanic acidNot Available
FidarestatNot Available
SorbinilNot Available
2-IminobiotinNot Available
HistidinolNot Available
N-acetylhistamineNot Available
FluspirileneAn antipsychotic agent used in the treatment of schizophrenia.
EnoximoneFor the treatment of congestive heart failure.
AcadesineInvestigated for use/treatment in cardiac reperfusion injury, cardiovascular disorders, and coronary artery disease.
LofexidineA centrally acting alpha2-adrenergic agonist used for the symptomatic treatment of acute opioid withdrawal syndrome to facilitate abrupt opioid discontinuation in adults.
AzimilideInvestigated for use/treatment in arrhythmia and atrial fibrillation.
PretomanidPart of a three-drug regimen used for the treatment of extensively drug-resistant and multidrug-resistant pulmonary tuberculosis.
OMS-103HPInvestigated for use/treatment in inflammatory disorders (unspecified), knee replacement, orthopedic surgery, and pain (acute or chronic).
HistamineAn ingredient of topical drugs for the relief of joint pain or muscle aches and pains.
EvofosfamideInvestigated for use/treatment in solid tumors.
AviptadilNot Annotated
NaphazolineA sympathomimetic vasoconstrictor used for the symptomatic relief of redness and itching of the eye, and nasal congestion.
AntazolineAn antihistamine agent used for the symptomatic treatment of nasal congestion and allergic conjunctivitis.
EnzalutamideAn androgen receptor inhibitor used to treat castration-resistant prostate cancer.
IsoconazoleIsoconazole is an azole antifungal drug that has similar effectiveness to clotrimazole in the treatment of foot and vaginal infections.
AllantoinAn ingredient used in skin care products to relieve irritation and protect minor cuts, scrapes, and burns.
MedetomidineMedetomidine is a synthetic compound used as a surgical anesthetic and analgesic. It is normally found as its hydrochloride salt, medetomidine hydrochloride. Medetomidine is an intravenously available alpha-2 adrenergic agonist....
DelamanidAn antibiotic used to treat multidrug resistant tuberculosis.
MisonidazoleMisonidazole is under investigation in clinical trial NCT00038038 (Assessment of Head and Neck Tumor Hypoxia Using 18F-Fluoromisonidazole).
ImidaprilImidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.
CreatinineCreatinine has been used in trials studying the treatment of Amyotrophic Lateral Sclerosis.
BenznidazoleA trypanocidal agent used to treat Chagas disease.
NimorazoleNimorazole has been used in trials studying the treatment of Hypoxia, Radiotherapy, Hypoxic Modification, Gene Profile, Gene Signature, and Head and Neck Squamous Cell Carcinoma, among others.
FexinidazoleFexinidazole has been investigated for the treatment of Disease, Chagas and South American Trypanosomiasis.
GLPG-0492Glpg0492 is under investigation in clinical trial NCT01130818 (First-in-Human Single Ascending Dose of GLPG0492).
PimonidazolePimonidazole is under investigation for the diagnostic of Prostate Cancer and Head and Neck Cancer.
IdazoxanIdazoxan has been used in trials studying the basic science of Molecular Imaging, Alzheimer Disease, and Major Depressive Disorder.
EtanidazoleEtanidazole has been used in trials studying the diagnostic of Adult Ependymoma, Malignant Ascites, Adult Gliosarcoma, Adult Mixed Glioma, and Adult Glioblastoma, among others.
SecnidazoleA nitroimidazole antibiotic used to treat bacterial vaginosis.
OrnidazoleOrnidazole has been used in trials studying the prevention of Elective Colorectal Surgery.
AzanidazoleNot Annotated
FlutrimazoleNot Annotated
TolonidineNot Annotated
ClodantoinNot Annotated
NiridazoleNot Annotated
MorinidazoleMorinidazole is under investigation in clinical trial NCT03380793 (A Trial to Assess the Efficacy and Safety of Morinidazole in Patients With Appendicitis).
Fluoroazomycin arabinoside F-18Fluoroazomycin arabinoside F-18 is under investigation in clinical trial NCT03257150 (A Study of the Use of Irreversible Electroporation in Pancreatic Ductal Cancer).
Zoledronic acidA bisphosphonate used to treat malignancy associated hypercalcemia, multiple myeloma, and bone metastasis from solid tumors.
ApalutamideAn androgen receptor inhibitor used to treat non metastatic, castration resistant prostate cancer.
PCO-371PCO-371 is under investigation in clinical trial NCT02475616 (A Single Ascending Dose Study of PCO371 in Healthy Volunteers).
DethiobiotinNot Available
RilematovirRilematovir is under investigation in clinical trial NCT04056611 (Effects of JNJ-53718678 in Adult and Adolescent Participants Who Had a Hematopoietic Stem Cell Transplantation and Who Are Infected With Respiratory Syncytial...
Drugs & Drug Targets
DrugTargetType
BiotinPropionyl-CoA carboxylase beta chain, mitochondrialtarget
BiotinBiotin--protein ligasetarget
BiotinMethylcrotonoyl-CoA carboxylase beta chain, mitochondrialtarget
BiotinAcetyl-CoA carboxylase 2target
BiotinMethylcrotonoyl-CoA carboxylase subunit alpha, mitochondrialtarget
BiotinPyruvate carboxylase, mitochondrialtarget
BiotinPropionyl-CoA carboxylase alpha chain, mitochondrialtarget
BiotinAcetyl-CoA carboxylase 1target
BiotinCytochrome P450 1B1enzyme
BiotinSodium-dependent multivitamin transportertransporter
BiotinSodium-coupled monocarboxylate transporter 1transporter
PhenytoinSodium channel protein type 5 subunit alphatarget
PhenytoinSodium channel protein type 1 subunit alphatarget
PhenytoinCytochrome P450 2C8enzyme
PhenytoinCytochrome P450 2C19enzyme
PhenytoinCytochrome P450 2C9enzyme
PhenytoinCytochrome P450 2B6enzyme
PhenytoinCytochrome P450 3A5enzyme
PhenytoinSerum albumincarrier
PhenytoinCytochrome P450 3A4enzyme
PhenytoinSolute carrier organic anion transporter family member 1C1transporter
PhenytoinP-glycoprotein 1transporter
PhenytoinCanalicular multispecific organic anion transporter 1transporter
PhenytoinCytochrome P450 11B1, mitochondrialenzyme
PhenytoinCytochrome P450 3A7enzyme
PhenytoinNuclear receptor subfamily 1 group I member 2target
PhenytoinSodium channel subunit beta-1target
PhenytoinSodium channel protein type 3 subunit alphatarget
PhenytoinUDP-glucuronosyltransferase 1-1enzyme
PhenytoinUDP-glucuronosyltransferase 1-6enzyme
PhenytoinUDP-glucuronosyltransferase 1-9enzyme
PhenytoinThyroxine-binding globulincarrier
PhenytoinPotassium voltage-gated channel subfamily H member 2target
PhenytoinVoltage-dependent L-type calcium channeltarget
PhenytoinSodium channel protein type 2 subunit alphatarget
PhenytoinSodium channel protein type 8 subunit alphatarget
PhenytoinGABA(A) Receptortarget
PhenytoinCytochrome P450 1A2enzyme
PhenytoinCytochrome P450 2A6enzyme
PhenytoinCytochrome P450 2D6enzyme
PhenytoinCytochrome P450 2E1enzyme
PhenytoinEpoxide hydrolase 1enzyme
PhenytoinUDP-glucuronosyltransferase 1-4enzyme
PhenytoinCatechol O-methyltransferaseenzyme
PhenytoinNAD(P)H dehydrogenase [quinone] 1enzyme
PhenytoinCytochrome P450 2C18enzyme
ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
ClotrimazoleCytochrome P450 2D6enzyme
ClotrimazoleCytochrome P450 2C8enzyme
ClotrimazoleCytochrome P450 3A4enzyme
ClotrimazoleCytochrome P450 2B6enzyme
ClotrimazoleP-glycoprotein 1transporter
ClotrimazoleCytochrome P450 2A6enzyme
ClotrimazoleCytochrome P450 2C9enzyme
ClotrimazoleCytochrome P450 2E1enzyme
ClotrimazoleCytochrome P450 3A7enzyme
ClotrimazoleCytochrome P450 51target
ClotrimazoleNuclear receptor subfamily 1 group I member 2target
ClotrimazoleHydroxycarboxylic acid receptor 2target
ClotrimazoleBile salt export pumptransporter
ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
ClotrimazoleErgosteroltarget
OlmesartanType-1 angiotensin II receptortarget
OlmesartanCanalicular multispecific organic anion transporter 1transporter
OlmesartanSolute carrier organic anion transporter family member 1B3transporter
OlmesartanSolute carrier organic anion transporter family member 1B1transporter
OlmesartanBile salt export pumptransporter
EtomidateGamma-aminobutyric acid receptor subunit alpha-1target
EtomidateAlpha-2B adrenergic receptortarget
EtomidateSolute carrier family 2, facilitated glucose transporter member 1carrier
EtomidateCytochrome P450 11B1, mitochondrialenzyme
EtomidateCytochrome P450 11B2, mitochondrialenzyme
EtomidateGABA(A) Receptortarget
CarbimazoleThyroid peroxidasetarget
CarbimazoleCytochrome P450 19A1enzyme
CimetidineHistamine H2 receptortarget
CimetidineCytochrome P450 1A2enzyme
CimetidineCytochrome P450 2D6enzyme
CimetidineCytochrome P450 2C19enzyme
CimetidineCytochrome P450 3A4enzyme
CimetidineCytochrome P450 3A5enzyme
CimetidineP-glycoprotein 1transporter
CimetidineSolute carrier family 22 member 2transporter
CimetidineSolute carrier family 22 member 1transporter
CimetidineSolute carrier family 22 member 3transporter
CimetidineSolute carrier family 22 member 5transporter
CimetidineSolute carrier family 22 member 6transporter
CimetidineSolute carrier family 22 member 8transporter
CimetidineMultidrug and toxin extrusion protein 1transporter
CimetidineSolute carrier family 22 member 4transporter
CimetidineSolute carrier family 22 member 11transporter
CimetidineSolute carrier family 22 member 7transporter
CimetidineCytochrome P450 11B1, mitochondrialenzyme
CimetidineCytochrome P450 2C8enzyme
CimetidineCytochrome P450 2C9enzyme
CimetidineCytochrome P450 2E1enzyme
CimetidineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
CimetidineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
CimetidineBile salt export pumptransporter
CimetidineMultidrug and toxin extrusion protein 2transporter
MephenytoinSodium channel protein type 5 subunit alphatarget
MephenytoinCytochrome P450 2B6enzyme
MephenytoinCytochrome P450 2C9enzyme
MephenytoinCytochrome P450 2C19enzyme
MephenytoinCytochrome P450 1A2enzyme
MephenytoinCytochrome P450 2D6enzyme
MephenytoinCytochrome P450 2C8enzyme
MephenytoinNuclear receptor subfamily 1 group I member 2target
MephenytoinThyroxine-binding globulincarrier
ClonidineAlpha-2A adrenergic receptortarget
ClonidineCytochrome P450 2D6enzyme
ClonidineAlpha-2B adrenergic receptortarget
ClonidineAlpha-2C adrenergic receptortarget
ClonidineSolute carrier family 22 member 3transporter
ClonidineSolute carrier family 22 member 5transporter
ClonidineSolute carrier family 22 member 4transporter
ClonidineP-glycoprotein 1transporter
ClonidineCytochrome P450 1A2enzyme
ClonidineCytochrome P450 3A4enzyme
ClonidineCytochrome P450 1A1enzyme
ClonidineCytochrome P450 3A5enzyme
ClonidineAlpha-1A adrenergic receptortarget
ClonidineAlpha-1B adrenergic receptortarget
ClonidineAlpha-1D adrenergic receptortarget
ClonidineSerum albumincarrier
DexmedetomidineAlpha-2A adrenergic receptortarget
DexmedetomidineCytochrome P450 2E1enzyme
DexmedetomidineCytochrome P450 1A2enzyme
DexmedetomidineCytochrome P450 1A1enzyme
DexmedetomidineCytochrome P450 2D6enzyme
NilutamideAndrogen receptortarget
NilutamideCytochrome P450 2C19enzyme
NilutamideNADPH--cytochrome P450 reductaseenzyme
LosartanType-1 angiotensin II receptortarget
LosartanCytochrome P450 3A4enzyme
LosartanCytochrome P450 2C9enzyme
LosartanP-glycoprotein 1transporter
LosartanSolute carrier family 22 member 6transporter
LosartanUDP-glucuronosyltransferase 1-1enzyme
LosartanUDP-glucuronosyltransferase 1-3enzyme
LosartanUDP-glucuronosyltransferase 1-10enzyme
LosartanUDP-glucuronosyltransferase 2B7enzyme
LosartanUDP-glucuronosyltransferase 2B17enzyme
LosartanCytochrome P450 2C19enzyme
LosartanSerum albumincarrier
LosartanSolute carrier family 22 member 12transporter
LosartanSolute carrier family 2, facilitated glucose transporter member 9transporter
LosartanBile salt export pumptransporter
LosartanCytochrome P450 2C8enzyme
PhentolamineAlpha-2A adrenergic receptortarget
PhentolamineAlpha-1A adrenergic receptortarget
PhentolamineAlpha-1B adrenergic receptortarget
PhentolamineAlpha-1D adrenergic receptortarget
TizanidineAlpha-2 adrenergic receptorstarget
TizanidineCytochrome P450 1A2enzyme
TizanidineNischarintarget
TizanidineAlpha-1 adrenergic receptorstarget
EthotoinSodium channel protein type 5 subunit alphatarget
EthotoinNuclear receptor subfamily 1 group I member 2target
EthotoinThyroxine-binding globulincarrier
MethimazoleThyroid peroxidasetarget
MethimazoleCytochrome P450 1A2enzyme
MethimazoleCytochrome P450 2A6enzyme
MethimazoleCytochrome P450 2B6enzyme
MethimazoleCytochrome P450 2C19enzyme
MethimazoleCytochrome P450 2C9enzyme
MethimazoleCytochrome P450 2D6enzyme
MethimazoleCytochrome P450 2E1enzyme
MethimazoleCytochrome P450 3A4enzyme
MethimazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
TolazolineAlpha-1A adrenergic receptortarget
TolazolineAlpha-2A adrenergic receptortarget
TolazolineHistamine H1 receptortarget
TolazolineHistamine H2 receptortarget
TolazolineAlpha-2C adrenergic receptortarget
TolazolineAlpha-2B adrenergic receptortarget
LevamisoleNeuronal acetylcholine receptor subunit alpha-3target
LevamisoleAlkaline phosphatase, placental-liketarget
LevamisoleAcetylcholine receptor subunit alpha-type unc-38target
LevamisoleAcetylcholine receptor subunit alpha-type unc-63target
LevamisoleAcetylcholine receptor subunit beta-type lev-1target
LevamisoleAcetylcholine receptor subunit beta-type unc-29target
DacarbazineDNA polymerase alpha subunit Btarget
DacarbazineCytochrome P450 1A1enzyme
DacarbazineCytochrome P450 1A2enzyme
DacarbazineCytochrome P450 2E1enzyme
Dacarbazine6-phosphogluconate dehydrogenase, decarboxylatingtarget
DacarbazineDNAtarget
TemozolomideDNAtarget
VardenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
VardenafilCytochrome P450 3A4enzyme
VardenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilCytochrome P450 3A5enzyme
VardenafilP-glycoprotein 1transporter
Ondansetron5-hydroxytryptamine receptor 3Atarget
OndansetronCytochrome P450 3A4enzyme
OndansetronCytochrome P450 1A2enzyme
OndansetronCytochrome P450 2D6enzyme
OndansetronCytochrome P450 3A5enzyme
OndansetronCytochrome P450 3A7enzyme
Ondansetron5-hydroxytryptamine receptor 4target
Ondansetron5-hydroxytryptamine receptor 1Atarget
Ondansetron5-hydroxytryptamine receptor 1Btarget
OndansetronMu-type opioid receptortarget
OndansetronCytochrome P450 2C9enzyme
OndansetronCytochrome P450 2E1enzyme
TinidazoleCytochrome P450 3A4enzyme
TinidazoleDNAtarget
TinidazoleBile salt export pumptransporter
MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
MetronidazoleCytochrome P450 2C9enzyme
MetronidazoleCytochrome P450 3A4enzyme
MetronidazoleCytochrome P450 2C8enzyme
MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
MetronidazoleAnaerobic bacterial DNAtarget
MetronidazoleProtozoal DNAtarget
MetronidazoleP-glycoprotein 1transporter
MetronidazoleCytochrome P450 2A6enzyme
MetronidazoleCytochrome P450 3A5enzyme
MetronidazoleCytochrome P450 3A7enzyme
OxymetazolineAlpha-1A adrenergic receptortarget
OxymetazolineAlpha-2A adrenergic receptortarget
OxymetazolineAlpha-2C adrenergic receptortarget
OxymetazolineAlpha-2B adrenergic receptortarget
OxymetazolineAlpha-1B adrenergic receptortarget
OxymetazolineAlpha-1D adrenergic receptortarget
ApraclonidineAlpha-2A adrenergic receptortarget
ApraclonidineAlpha-1A adrenergic receptortarget
ApraclonidineAlpha-2B adrenergic receptortarget
MiconazoleCytochrome P450 2C9enzyme
MiconazoleCytochrome P450 2D6enzyme
MiconazoleCytochrome P450 3A4enzyme
MiconazoleP-glycoprotein 1transporter
MiconazoleCytochrome P450 51target
MiconazoleNitric oxide synthase, endothelialtarget
MiconazoleNitric oxide synthase, inducibletarget
MiconazoleCalcium-activated potassium channel subunit alpha-1target
MiconazoleCalcium-activated potassium channel subunit beta-1target
MiconazoleCalcium-activated potassium channel subunit beta-2target
MiconazoleCalcium-activated potassium channel subunit beta-3target
MiconazoleCalcium-activated potassium channel subunit beta-4target
MiconazoleIntermediate conductance calcium-activated potassium channel protein 4target
MiconazoleSmall conductance calcium-activated potassium channel protein 1target
MiconazoleSmall conductance calcium-activated potassium channel protein 2target
MiconazoleSmall conductance calcium-activated potassium channel protein 3target
MiconazolePotassium voltage-gated channel subfamily H member 2target
MiconazolePotassium voltage-gated channel subfamily H member 6target
MiconazolePotassium voltage-gated channel subfamily H member 7target
MiconazoleCytochrome P450 11B1, mitochondrialenzyme
MiconazoleCytochrome P450 2A6enzyme
MiconazoleCytochrome P450 2B6enzyme
MiconazoleCytochrome P450 2C19enzyme
MiconazoleCytochrome P450 2E1enzyme
MiconazoleNuclear receptor subfamily 1 group I member 2target
MiconazoleLanosterol 14-alpha demethylaseenzyme
MiconazoleCytochrome P450 19A1enzyme
TrimethaphanNeuronal acetylcholine receptor subunit alpha-10target
TrimethaphanCholinesteraseenzyme
EconazoleCytochrome P450 19A1enzyme
EconazoleCytochrome P450 2E1enzyme
EconazoleCytochrome P450 3A4enzyme
EconazoleCytochrome P450 51target
EconazoleNuclear receptor subfamily 1 group I member 2target
DantroleneRyanodine receptor 1target
DantroleneThyroxine-binding globulincarrier
FosphenytoinSodium channel protein type 5 subunit alphatarget
FosphenytoinCytochrome P450 2C19enzyme
FosphenytoinCytochrome P450 2B6enzyme
FosphenytoinCytochrome P450 2C9enzyme
FosphenytoinCytochrome P450 3A4enzyme
FosphenytoinSerum albumincarrier
FosphenytoinCytochrome P450 1A2enzyme
FosphenytoinUDP-glucuronosyltransferase 1-6enzyme
FosphenytoinUDP-glucuronosyltransferase 1-9enzyme
FosphenytoinThyroxine-binding globulincarrier
AICA ribonucleotideBifunctional purine biosynthesis protein PURHtarget
trans-urocanic acidUrocanate hydratasetarget
FidarestatAldose reductasetarget
FidarestatAldo-keto reductase family 1 member B10target
SorbinilAldose reductasetarget
2-IminobiotinStreptavidintarget
HistidinolHistidinol dehydrogenasetarget
HistidinolHistidine--tRNA ligasetarget
N-acetylhistamineGlutaminyl-peptide cyclotransferasetarget
FluspirileneDopamine D2 receptortarget
Fluspirilene5-hydroxytryptamine receptor 2Atarget
FluspirileneVoltage-dependent calcium channel gamma-1 subunittarget
FluspirileneCytochrome P450 3A4enzyme
EnoximonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
LofexidineAlpha-2A adrenergic receptortarget
LofexidineAlpha-1A adrenergic receptortarget
Lofexidine5-hydroxytryptamine receptor 1Atarget
Lofexidine5-hydroxytryptamine receptor 7target
Lofexidine5-hydroxytryptamine receptor 2Ctarget
Lofexidine5-hydroxytryptamine receptor 1Dtarget
LofexidineCytochrome P450 2D6enzyme
LofexidineCytochrome P450 1A2enzyme
LofexidineCytochrome P450 2C19enzyme
LofexidineATP-binding cassette sub-family B member 5transporter
LofexidineMultidrug and toxin extrusion protein 1transporter
AzimilidePotassium voltage-gated channel subfamily E member 1target
AzimilidePotassium voltage-gated channel subfamily KQT member 1target
AzimilidePotassium voltage-gated channel subfamily H member 2target
AzimilideCytochrome P450 1A1enzyme
AzimilideCytochrome P450 3A4enzyme
AzimilideCytochrome P450 3A5enzyme
AzimilideCytochrome P450 2D6enzyme
PretomanidDeazaflavin-dependent nitroreductaseenzyme
PretomanidSolute carrier family 22 member 8transporter
PretomanidCytochrome P450 3A4enzyme
PretomanidFatty acid synthetasetarget
PretomanidUncharacterized MFS-type transporter EfpAtarget
PretomanidNucleoid-associated protein Lsr2target
PretomanidCyd operon, Mycobacterium tuberculosistarget
PretomanidEnoyl-[acyl-carrier-protein] reductase [NADH]target
OMS-103HPTumor necrosis factortarget
OMS-103HPInterleukin-1 receptor type 1target
HistamineHistamine H1 receptortarget
HistamineHistamine H2 receptortarget
HistamineHistamine H3 receptortarget
HistamineHistamine N-methyltransferaseenzyme
HistamineSolute carrier family 22 member 2transporter
HistamineSolute carrier family 22 member 1transporter
HistamineSolute carrier family 22 member 3transporter
HistamineSolute carrier family 22 member 5transporter
HistamineHistamine H4 receptortarget
HistamineSynaptic vesicular amine transportertarget
NaphazolineAlpha-1A adrenergic receptortarget
NaphazolineAlpha-2A adrenergic receptortarget
AntazolineHistamine H1 receptortarget
EnzalutamideSerum albumincarrier
EnzalutamideCytochrome P450 2C8enzyme
EnzalutamideCytochrome P450 3A4enzyme
EnzalutamideAndrogen receptortarget
EnzalutamideCytochrome P450 2C9enzyme
EnzalutamideCytochrome P450 2C19enzyme
EnzalutamideCytochrome P450 2B6enzyme
EnzalutamideCytochrome P450 3A5enzyme
EnzalutamideP-glycoprotein 1transporter
EnzalutamideThyroxine-binding globulincarrier
AllantoinThyroxine-binding globulincarrier
DelamanidDeazaflavin-dependent nitroreductaseenzyme
DelamanidCytochrome P450 3A4enzyme
DelamanidSerum albumincarrier
DelamanidAlpha-1-acid glycoprotein 1carrier
Zoledronic acidFarnesyl pyrophosphate synthasetarget
Zoledronic acidGeranylgeranyl pyrophosphate synthasetarget
Zoledronic acidHydroxylapatitetarget
Zoledronic acidMultidrug resistance-associated protein 1transporter
ApalutamideAndrogen receptortarget
ApalutamideCytochrome P450 3A4enzyme
ApalutamideCytochrome P450 2C8enzyme
ApalutamideCytochrome P450 2C19enzyme
ApalutamideCytochrome P450 2C9enzyme
ApalutamideP-glycoprotein 1transporter
ApalutamideATP-binding cassette sub-family G member 2transporter
ApalutamideSolute carrier organic anion transporter family member 1B1transporter
ApalutamideSolute carrier family 22 member 2transporter
ApalutamideSolute carrier family 22 member 8transporter
ApalutamideMultidrug and toxin extrusion protein 2transporter
ApalutamideGABA(A) Receptortarget
ApalutamideMultidrug and toxin extrusion protein 1transporter
DethiobiotinATP-dependent dethiobiotin synthetase BioD 1target
DethiobiotinBiotin synthasetarget
DethiobiotinATP-dependent dethiobiotin synthetase BioDtarget