Hypolipidemic Agents

Substances that lower the levels of certain LIPIDS in the BLOOD. They are used to treat HYPERLIPIDEMIAS.
DrugDrug NameDrug Indication
DB00122CholineFor nutritional supplementation, also for treating dietary shortage or imbalance
DB00159IcosapentEPA can be used for lowering elevated triglycerides in those who are hyperglyceridemic. In addition, EPA may play a therapeutic role in patients with cystic fibrosis by reducing disease severity and may play a similar role in type 2 diabetics in slowing the progression of diabetic nephropathy.
DB00175PravastatinFor the treatment of hypercholesterolemia and to reduce the risk of cardiovascular disease.
DB00227LovastatinFor management as an adjunct to diet to reduce elevated total-C, LDL-C, apo B, and TG levels in patients with primary hypercholesterolemia and mixed dyslipidemia. For primary prevention of coronary heart disease and to slow progression of coronary atherosclerosis in patients with coronary heart disease.
DB00375ColestipolFor use, as adjunctive therapy to diet, for the reduction of elevated serum total and LDL-C in patients with primary hypercholesterolemia (elevated LDL-C) who do not respond adequately to diet.
DB00439CerivastatinUsed as an adjunct to diet for the reduction of elevated total and LDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia (Fredrickson Types IIa and IIb) when the response to dietary restriction of saturated fat and cholesterol and other non-pharmacological measures alone has been inadequate.
DB00609EthionamideFor use in the treatment of pulmonary and extrapulmonary tuberculosis when other antitubercular drugs have failed.
DB00627NiacinFor the treatment of type IV and V hyperlipidemia. It is indicated as ajunctive therapy.
DB00636ClofibrateFor Primary Dysbetalipoproteinemia (Type III hyperlipidemia) that does not respond adequately to diet. This helps control high cholesterol and high triglyceride levels.
DB00641SimvastatinFor the treatment of hypercholesterolemia and for the reduction in the risk of cardiac heart disease mortality and cardiovascular events. It can also be used in adolescent patients for the treatment of heterozygous familial hypercholesterolemia.
DB00930ColesevelamFor use, alone or in combination with an HMG-CoA reductase inhibitor, as adjunctive therapy to diet and exercise for the reduction of elevated LDL cholesterol in patients with primary hypercholesterolemia (Fredrickson Type IIa).
DB00951IsoniazidFor the treatment of all forms of tuberculosis in which organisms are susceptible.
DB00973EzetimibeFor use as adjunctive therapy to diet for the reduction of elevated total-C, LDL-C, and Apo B in patients with primary (heterozygous familial and non-familial) hypercholesterolemia.
DB01034CeruleninFor use as a biochemical tool, Cerulenin is shown to cause dramatic weight loss in animals
DB01039FenofibrateFor use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb)
DB01076AtorvastatinMay be used as primary prevention in individuals with multiple risk factors for coronary heart disease (CHD) and as secondary prevention in individuals with CHD to reduce the risk of myocardial infarction (MI), stroke, angina, and revascularization procedures. May be used to reduce the risk of cardiovascular events in patients with acute coronary syndrome (ACS). May be used in the treatment of primary hypercholesterolemia and mixed dyslipidemia, homozygous familial hypercholesterolemia, primary dysbetalipoproteinemia, and/or hypertriglyeridemia as an adjunct to dietary therapy to decrease serum total and low-density lipoprotein cholesterol (LDL-C), apolipoprotein B (apoB), and triglyceride concentrations, while increasing high-density lipoprotein cholesterol (HDL-C) levels.
DB01095FluvastatinTo be used as an adjunct to dietary therapy to prevent cardiovascular events. May be used as secondary prevention in patients with coronary heart disease (CHD) to reduce the risk of requiring coronary revascularization procedures, for reducing progression of coronary atherosclerosis in hypercholesterolemic patients with CHD, and for the treatment of primary hypercholesterolemia and mixed dyslidipidemia.
DB01098RosuvastatinUsed as an adjunct to dietary therapy to treat primary hyperlipidemia (heterozygous familial and nonfamilial), mixed dyslipidemia and hypertriglyceridemia. Also indicated for homozygous familial hypercholesterolemia as an adjunct to other lipid-lowering therapies or when other such therapies are not available. Furthermore, it is used to slow the progression of atherosclerosis and for primary prevention of cardiovascular disease.
DB01241GemfibrozilFor treatment of adult patients with very high elevations of serum triglyceride levels (types IV and V hyperlipidemia) who are at risk of developing pancreatitis (inflammation of the pancreas) and who do not respond adequately to a strict diet.
DB01393BezafibrateFor the treatment of primary hyperlipidaemia types IIa, IIb, III, IV and V (Fredrickson classification) corresponding to groups I, II and III of the European Atherosclerosis Society guidelines - when diet alone or improvements in lifestyle such as increased exercise or weight reduction do not lead to an adequate response. Also for the treatment of secondary hyperlipidaemias, e.g. severe hypertriglyceridemias, when sufficient improvement does not occur after correction of the underlying disorder (e.g. diabetes mellitus).
DB01432CholestyramineIndicated as adjunctive therapy to diet for the reduction of elevated serum cholesterol in patients with primary hypercholesterolemia (elevated low density lipoprotein [LDL] cholesterol) who do not respond adequately to diet. Also for the relief of pruritus associated with partial biliary obstruction.
DB01599ProbucolUsed to lower LDL and HDL cholesterol.
DB05528MipomersenUsed in patients with homozygous familial hypercholesterolemia as an adjunct to diet and other lipid-lowering medications.
DB06271SulodexideSulodexide has been used clinically for the prophylaxis and treatment of vascular diseases with increased risk of thrombosis, including intermittent claudication, peripheral arterial occlusive disease and post-myocardial infarc-tion. Also investigated in the treatment of diabetic kidney disease and diabetic neuropathy. New anti-inflammatory properties have also extended its use in venous disease.
DB06693MevastatinNot used therapeutically due to its many side effects.
DB06748Ginsenoside CNot Available
DB06756Glycine betaineBetaine is indicated for the treatment of homocystinuria to decrease elevated homocysteine blood levels. Included within the category of homocystinuria are deficiencies or defects in: 1. cystathionine beta-synthase (CBS), 2. 5,10-methylenetetrahydrofolate reductase (MTHFR), 3. cobalamin cofactor metabolism (cbl).
DB08604TriclosanTriclosan is used in a variety of common household products, including soaps, mouthwashes, dish detergents, toothpastes, deodorants, and hand sanitizers. It is also used in health care settings in surgical scrubs and personnel hand washes.
DB08860PitavastatinPitavastatin is used to lower serum levels of total cholesterol, LDL-C, apolipoprotein B, and triglycerides, and raise levels of HDL-C for the treatment of dyslipidemia.
DB08887Icosapent ethylIcosapent ethyl is used as adjunct therapy to reduce triglyceride (TG) levels in adults with severe (>500 mg/dL) hypertriglyceridemia.
DB08983EtofibrateNot Available
DB09022BenfluorexNot Available
DB09055AcipimoxUsed in the treatment of hyperlipidemias (abnormally elevated levels of any or all lipids and/or lipoproteins in the blood).
DB11234PoliglusamNot Available
DB11293Rice bran oilNot Available
DB11358Evening primrose oilNot Available
DB11655EvacetrapibNot Available
DB11780AllicinNot Available
DB11936Bempedoic acidNot Available
DB12181DalcetrapibNot Available
DB13873Fenofibric acidFor use as adjunctive therapy to diet to reduce elevated LDL-C, Total-C,Triglycerides and Apo B, and to increase HDL-C in adult patients with primary hypercholesterolemia or mixed dyslipidemia (Fredrickson Types IIa and IIb).
DrugDrug NameTargetType
DB00122CholineCholine-phosphate cytidylyltransferase Btarget
DB00122CholineAcetylcholinesterasetarget
DB00122CholineCholine-phosphate cytidylyltransferase Atarget
DB00122CholinePhospholipase D2target
DB00122CholineCholinesterasetarget
DB00122CholinePhospholipase D1target
DB00122CholinePhosphoethanolamine/phosphocholine phosphatasetarget
DB00122CholineSolute carrier family 22 member 2transporter
DB00122CholineSolute carrier family 22 member 1transporter
DB00122CholineSolute carrier family 22 member 3transporter
DB00122CholineSolute carrier family 22 member 5transporter
DB00122CholineSolute carrier family 22 member 4transporter
DB00122CholineCholine/ethanolaminephosphotransferase 1enzyme
DB00122CholineCholine transporter-like protein 1transporter
DB00122CholineCholine transporter-like protein 4transporter
DB00122CholineCholine transporter-like protein 2transporter
DB00122CholineCholine transporter-like protein 3transporter
DB00122CholineCholine/ethanolamine kinaseenzyme
DB00122CholineCholine O-acetyltransferaseenzyme
DB00122CholineCholine kinase alphaenzyme
DB00122CholineCholine dehydrogenase, mitochondrialenzyme
DB00122CholineHigh affinity choline transporter 1transporter
DB00122CholineNeuronal acetylcholine receptor subunit alpha-7target
DB00159IcosapentProstaglandin G/H synthase 2target
DB00159IcosapentProstaglandin G/H synthase 1target
DB00159IcosapentFree fatty acid receptor 1target
DB00159IcosapentFatty acid-binding protein, braincarrier
DB00159IcosapentFatty acid desaturase 1target
DB00159IcosapentLong-chain-fatty-acid--CoA ligase 4target
DB00159IcosapentLong-chain-fatty-acid--CoA ligase 3target
DB00159IcosapentSodium/calcium exchanger 1target
DB00159IcosapentPeroxisome proliferator-activated receptor gammatarget
DB00159IcosapentPeroxisome proliferator-activated receptor deltatarget
DB00159IcosapentTransient receptor potential cation channel subfamily V member 1target
DB00159IcosapentPeroxisome proliferator-activated receptor alphatarget
DB00159IcosapentSerum albumincarrier
DB00175Pravastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00175PravastatinSolute carrier organic anion transporter family member 2B1transporter
DB00175PravastatinMultidrug resistance protein 1transporter
DB00175PravastatinSolute carrier organic anion transporter family member 1A2transporter
DB00175PravastatinSolute carrier family 22 member 6transporter
DB00175PravastatinSolute carrier family 22 member 8transporter
DB00175PravastatinCanalicular multispecific organic anion transporter 1transporter
DB00175PravastatinSolute carrier family 22 member 11transporter
DB00175PravastatinATP-binding cassette sub-family G member 2transporter
DB00175PravastatinSolute carrier family 22 member 7transporter
DB00175PravastatinSolute carrier organic anion transporter family member 1B1transporter
DB00175PravastatinCytochrome P450 2C8enzyme
DB00175PravastatinCytochrome P450 2C9enzyme
DB00175PravastatinCytochrome P450 2D6enzyme
DB00175PravastatinCytochrome P450 3A4enzyme
DB00175PravastatinCytochrome P450 3A5enzyme
DB00175PravastatinMonocarboxylate transporter 1transporter
DB00175PravastatinBile salt export pumptransporter
DB00175PravastatinSolute carrier organic anion transporter family member 1B3transporter
DB00227Lovastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00227LovastatinCytochrome P450 3A4enzyme
DB00227LovastatinCytochrome P450 2C8enzyme
DB00227LovastatinIntegrin alpha-Ltarget
DB00227LovastatinHistone deacetylase 2target
DB00227LovastatinSerum paraoxonase/lactonase 3enzyme
DB00227LovastatinCytochrome P450 2C9enzyme
DB00227LovastatinCytochrome P450 2C19enzyme
DB00227LovastatinCytochrome P450 3A5enzyme
DB00227LovastatinCytochrome P450 3A7enzyme
DB00227LovastatinMultidrug resistance protein 1transporter
DB00227LovastatinSolute carrier organic anion transporter family member 1A2transporter
DB00227LovastatinSolute carrier organic anion transporter family member 1B1transporter
DB00227LovastatinCytochrome P450 2D6enzyme
DB00227LovastatinUDP-glucuronosyltransferase 1-1enzyme
DB00227LovastatinUDP-glucuronosyltransferase 1-3enzyme
DB00227LovastatinUDP-glucuronosyltransferase 2B7enzyme
DB00227LovastatinCanalicular multispecific organic anion transporter 1transporter
DB00375ColestipolBile acidstarget
DB00439Cerivastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00439CerivastatinCytochrome P450 2C8enzyme
DB00439CerivastatinCytochrome P450 3A4enzyme
DB00439CerivastatinCytochrome P450 2D6enzyme
DB00439CerivastatinCytochrome P450 2C9enzyme
DB00439CerivastatinCytochrome P450 2C19enzyme
DB00439CerivastatinCytochrome P450 3A5enzyme
DB00439CerivastatinCytochrome P450 3A7enzyme
DB00439CerivastatinMultidrug resistance protein 1transporter
DB00439CerivastatinCanalicular multispecific organic anion transporter 1transporter
DB00439CerivastatinATP-binding cassette sub-family G member 2transporter
DB00439CerivastatinSolute carrier organic anion transporter family member 1B1transporter
DB00439CerivastatinCytochrome P450 2B6enzyme
DB00609EthionamideCatalase-peroxidasetarget
DB00609EthionamideEnoyl-[acyl-carrier-protein] reductase [NADH]target
DB00627NiacinHydroxycarboxylic acid receptor 2target
DB00627NiacinNicotinamide N-methyltransferasetarget
DB00627NiacinNicotinate-nucleotide pyrophosphorylase [carboxylating]target
DB00627NiacinHydroxycarboxylic acid receptor 3target
DB00627NiacinSolute carrier family 22 member 5transporter
DB00627NiacinSolute carrier organic anion transporter family member 2B1transporter
DB00627NiacinMonocarboxylate transporter 1transporter
DB00627NiacinCytochrome P450 2D6enzyme
DB00627NiacinSodium-coupled monocarboxylate transporter 1transporter
DB00627NiacinMonocarboxylate transporter 4transporter
DB00636ClofibratePeroxisome proliferator-activated receptor alphatarget
DB00636ClofibrateCytochrome P450 3A4enzyme
DB00636ClofibrateGlutathione S-transferase A2enzyme
DB00636ClofibrateCytochrome P450 2E1enzyme
DB00636ClofibrateCytochrome P450 1A1enzyme
DB00636ClofibrateCytochrome P450 2A6enzyme
DB00636ClofibrateCytochrome P450 2B6enzyme
DB00636ClofibrateCytochrome P450 4A11enzyme
DB00641Simvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB00641SimvastatinIntegrin beta-2target
DB00641SimvastatinCytochrome P450 3A4enzyme
DB00641SimvastatinCytochrome P450 2C8enzyme
DB00641SimvastatinCytochrome P450 2C9enzyme
DB00641SimvastatinCytochrome P450 2C19enzyme
DB00641SimvastatinCytochrome P450 3A5enzyme
DB00641SimvastatinCytochrome P450 3A7enzyme
DB00641SimvastatinMultidrug resistance protein 1transporter
DB00641SimvastatinSolute carrier organic anion transporter family member 1A2transporter
DB00641SimvastatinSolute carrier organic anion transporter family member 1B1transporter
DB00641SimvastatinCytochrome P450 2B6enzyme
DB00641SimvastatinCytochrome P450 2D6enzyme
DB00641SimvastatinUDP-glucuronosyltransferase 1-1enzyme
DB00641SimvastatinUDP-glucuronosyltransferase 1-3enzyme
DB00641SimvastatinUDP-glucuronosyltransferase 2B7enzyme
DB00641SimvastatinCanalicular multispecific organic anion transporter 1transporter
DB00641SimvastatinIntegrin alpha-Ltarget
DB00930ColesevelamBile acidstarget
DB00951IsoniazidCatalase-peroxidasetarget
DB00951IsoniazidEnoyl-[acyl-carrier-protein] reductase [NADH]target
DB00951IsoniazidCytochrome P450 2E1enzyme
DB00951IsoniazidCytochrome P450 1A2enzyme
DB00951IsoniazidCytochrome P450 2C9enzyme
DB00951IsoniazidCytochrome P450 2D6enzyme
DB00951IsoniazidCytochrome P450 2C19enzyme
DB00951IsoniazidCytochrome P450 3A4enzyme
DB00951IsoniazidArylamine N-acetyltransferase 2enzyme
DB00951IsoniazidArylamine N-acetyltransferaseenzyme
DB00951IsoniazidCytochrome P450 2A6enzyme
DB00951IsoniazidCytochrome P450 2C8enzyme
DB00951IsoniazidCytochrome P450 2C8target
DB00951IsoniazidCytochrome P450 1A2target
DB00951IsoniazidCytochrome P450 3A4target
DB00951IsoniazidCytochrome P450 2C19target
DB00951IsoniazidDihydrofolate reductasetarget
DB00951IsoniazidSerum albumincarrier
DB00973EzetimibeNiemann-Pick C1-like protein 1target
DB00973EzetimibeAminopeptidase Ntarget
DB00973EzetimibeSterol O-acyltransferase 1target
DB00973EzetimibeUDP-glucuronosyltransferase 1-1enzyme
DB00973EzetimibeUDP-glucuronosyltransferase 1-3enzyme
DB00973EzetimibeMultidrug resistance protein 1transporter
DB00973EzetimibeCanalicular multispecific organic anion transporter 1transporter
DB00973EzetimibeSolute carrier organic anion transporter family member 1B1transporter
DB00973EzetimibeUDP-glucuronosyltransferase 2B15enzyme
DB00973EzetimibeUDP-glucuronosyltransferase 2B7enzyme
DB00973EzetimibeCytochrome P450 3A4enzyme
DB00973EzetimibeATP-binding cassette sub-family G member 5transporter
DB00973EzetimibeCanalicular multispecific organic anion transporter 2transporter
DB00973EzetimibeATP-binding cassette sub-family G member 2transporter
DB00973EzetimibeATP-binding cassette sub-family G member 8transporter
DB01034Cerulenin3-oxoacyl-[acyl-carrier-protein] synthase 3target
DB01034Cerulenin3-oxoacyl-[acyl-carrier-protein] synthase 2target
DB01034Cerulenin3-oxoacyl-[acyl-carrier-protein] synthase 1target
DB01034CeruleninFatty acid synthasetarget
DB01039FenofibratePeroxisome proliferator-activated receptor alphatarget
DB01039FenofibrateMetalloproteinasetarget
DB01039FenofibrateCytochrome P450 2C8enzyme
DB01039FenofibrateCytochrome P450 2C9enzyme
DB01039FenofibrateCytochrome P450 3A4enzyme
DB01039FenofibratePeroxisome proliferator-activated receptor gammatarget
DB01039FenofibratePeroxisome proliferator-activated receptor deltatarget
DB01039FenofibrateNuclear receptor subfamily 1 group I member 2target
DB01076Atorvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01076AtorvastatinCytochrome P450 3A4enzyme
DB01076AtorvastatinDipeptidyl peptidase 4target
DB01076AtorvastatinCytochrome P450 2D6enzyme
DB01076AtorvastatinCytochrome P450 2C9enzyme
DB01076AtorvastatinCytochrome P450 2C19enzyme
DB01076AtorvastatinCytochrome P450 3A5enzyme
DB01076AtorvastatinCytochrome P450 3A7enzyme
DB01076AtorvastatinMultidrug resistance protein 1transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1A2transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01076AtorvastatinMultidrug resistance-associated protein 4transporter
DB01076AtorvastatinMultidrug resistance-associated protein 5transporter
DB01076AtorvastatinMultidrug resistance-associated protein 1transporter
DB01076AtorvastatinCytochrome P450 2B6enzyme
DB01076AtorvastatinCytochrome P450 2C8enzyme
DB01076AtorvastatinAryl hydrocarbon receptortarget
DB01076AtorvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01076AtorvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01076AtorvastatinUDP-glucuronosyltransferase 1-1enzyme
DB01076AtorvastatinUDP-glucuronosyltransferase 1-3enzyme
DB01076AtorvastatinUDP-glucuronosyltransferase 2B7enzyme
DB01076AtorvastatinCanalicular multispecific organic anion transporter 1transporter
DB01095Fluvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01095FluvastatinCytochrome P450 2C9enzyme
DB01095FluvastatinCytochrome P450 3A4enzyme
DB01095FluvastatinCytochrome P450 2C8enzyme
DB01095FluvastatinCytochrome P450 2D6enzyme
DB01095FluvastatinCytochrome P450 2C19enzyme
DB01095FluvastatinCytochrome P450 1A1enzyme
DB01095FluvastatinCytochrome P450 2B6enzyme
DB01095FluvastatinCytochrome P450 1A2enzyme
DB01095FluvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01095FluvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01095FluvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01095FluvastatinSolute carrier family 15 member 1transporter
DB01095FluvastatinCytochrome P450 3A5enzyme
DB01095FluvastatinUDP-glucuronosyltransferase 1-1enzyme
DB01095FluvastatinUDP-glucuronosyltransferase 1-3enzyme
DB01095FluvastatinUDP-glucuronosyltransferase 2B7enzyme
DB01095FluvastatinCanalicular multispecific organic anion transporter 1transporter
DB01098Rosuvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB01098RosuvastatinCytochrome P450 2C9enzyme
DB01098RosuvastatinMultidrug resistance-associated protein 4transporter
DB01098RosuvastatinMultidrug resistance-associated protein 1transporter
DB01098RosuvastatinCytochrome P450 2C19enzyme
DB01098RosuvastatinCytochrome P450 3A4enzyme
DB01098RosuvastatinCytochrome P450 3A5enzyme
DB01098RosuvastatinSolute carrier organic anion transporter family member 1A2transporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 1B3transporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 2B1transporter
DB01098RosuvastatinCystine/glutamate transportertransporter
DB01098RosuvastatinSolute carrier organic anion transporter family member 1B1transporter
DB01098RosuvastatinBile salt export pumptransporter
DB01098RosuvastatinATP-binding cassette sub-family G member 2transporter
DB01098RosuvastatinSerum albumincarrier
DB01098RosuvastatinCanalicular multispecific organic anion transporter 1transporter
DB01241GemfibrozilPeroxisome proliferator-activated receptor alphatarget
DB01241GemfibrozilCytochrome P450 3A4enzyme
DB01241GemfibrozilCytochrome P450 2C9enzyme
DB01241GemfibrozilCytochrome P450 2C8enzyme
DB01241GemfibrozilCytochrome P450 1A2enzyme
DB01241GemfibrozilCytochrome P450 2C19enzyme
DB01241GemfibrozilSolute carrier organic anion transporter family member 1B1transporter
DB01393BezafibratePeroxisome proliferator-activated receptor alphatarget
DB01393BezafibrateSolute carrier organic anion transporter family member 1B1transporter
DB01393BezafibratePeroxisome proliferator-activated receptor deltatarget
DB01393BezafibratePeroxisome proliferator-activated receptor gammatarget
DB01393BezafibrateCytochrome P450 1A1enzyme
DB01393BezafibrateCytochrome P450 2C8enzyme
DB01393BezafibrateCytochrome P450 3A4enzyme
DB01393BezafibrateNuclear receptor subfamily 1 group I member 2target
DB01393BezafibrateRetinoic acid receptor RXR-alphatarget
DB01393BezafibrateRetinoic acid receptor RXR-betatarget
DB01393BezafibrateRetinoic acid receptor RXR-gammatarget
DB01432CholestyramineBile acidstarget
DB01599ProbucolATP-binding cassette sub-family A member 1target
DB01599ProbucolLiver carboxylesterase 1target
DB05528MipomersenmRNA of ApoB-100target
DB06271SulodexideHeparin cofactor 2target
DB06271SulodexideAntithrombin-IIItarget
DB06693Mevastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB06693MevastatinLiver carboxylesterase 1enzyme
DB06756Glycine betaineCholinesteraseenzyme
DB06756Glycine betaineProline dehydrogenase 1, mitochondrialenzyme
DB06756Glycine betaineApoptosis regulator Bcl-2target
DB08604TriclosanEnoyl-[acyl-carrier-protein] reductase [NADH] FabItarget
DB08604TriclosanEnoyl-[acyl-carrier-protein] reductase [NADH]target
DB08604TriclosanEnoyl-[acyl-carrier-protein] reductase [NADH] FabItarget
DB08604TriclosanEnoyl-[acyl-carrier-protein] reductase [NADH]target
DB08604TriclosanEnoyl-[acyl-carrier-protein] reductase [NADPH] FabItarget
DB08604TriclosanNuclear receptor subfamily 1 group I member 2target
DB08604TriclosanAndrogen receptortarget
DB08604TriclosanNuclear receptor subfamily 1 group I member 3target
DB08604TriclosanPeroxisome proliferator-activated receptor gammatarget
DB08604TriclosanThyroid peroxidasetarget
DB08860PitavastatinSolute carrier organic anion transporter family member 1B1transporter
DB08860PitavastatinSolute carrier organic anion transporter family member 1B3transporter
DB08860PitavastatinUDP-glucuronosyltransferase 2B7enzyme
DB08860PitavastatinUDP-glucuronosyltransferase 1-3enzyme
DB08860PitavastatinCytochrome P450 2C9enzyme
DB08860PitavastatinCytochrome P450 2C8enzyme
DB08860Pitavastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
DB08860PitavastatinSolute carrier organic anion transporter family member 2B1transporter
DB08860PitavastatinSodium/bile acid cotransportertransporter
DB08860PitavastatinATP-binding cassette sub-family G member 2transporter
DB08860PitavastatinMultidrug resistance protein 1transporter
DB08860PitavastatinCanalicular multispecific organic anion transporter 1transporter
DB08860PitavastatinSerum albumincarrier
DB08860PitavastatinAlpha-1-acid glycoprotein 1carrier
DB13873Fenofibric acidPeroxisome proliferator-activated receptor alphatarget