Amino Acids, Diamino

DrugDrug NameDrug Indication
DB00123L-LysineSupplemental L-lysine has putative anti-herpes simplex virus activity. There is preliminary research suggesting that it may have some anti-osteoporotic activity.
DB00125L-ArginineUsed for nutritional supplementation, also for treating dietary shortage or imbalance.
DB00130L-GlutamineUsed for nutritional supplementation, also for treating dietary shortage or imbalance. Used to reduce the acute complications of sickle cell disease in adult and pediatric patients 5 years of age and older [FDA Label].
DB00138CystineIt has been claimed that L-cysteine has anti-inflammatory properties, that it can protect against various toxins, and that it might be helpful in osteoarthritis and rheumatoid arthritis. More research will have to be done before L-cysteine can be indicated for any of these conditions. Research to date has mostly been in animal models.
DB00155L-CitrullineUsed for nutritional supplementation, also for treating dietary shortage or imbalance.
DB00174AsparagineUsed for nutritional supplementation, also for treating dietary shortage or imbalance.
DB01686N,N-dimethylarginineNot Available
DB02011N-(Phosphonoacetyl)-L-OrnithineNot Available
DB03144N-Omega-Hydroxy-L-ArginineNot Available
DB03251RWJ-51084Not Available
DB04167AceglutamideNot Available
DB04189N2-(Carboxyethyl)-L-ArginineNot Available
DB04223NitroarginineNot Available
DB04527beta-HydroxyasparagineNot Available
DB04676DansyllysineNot Available
DB05668PalifosfamideInvestigated for use/treatment in cancer/tumors (unspecified), lymphoma (unspecified), and sarcoma.
DB06178TalotrexinInvestigated for use/treatment in solid tumors, lung cancer, leukemia (unspecified), and leukemia (lymphoid).
DB06243EflornithineEflornithine is indicated in the treatment of facial hirsutism (excessive hair growth).
DB09218ClonixinIndicated for use in the management of chronic arthritic conditions and certain soft tissue disorders associated with pain and inflammation.
DB11815TilarginineNot Available
DB11854AstodrimerNot Available
DB12750N-omega-nitro-L-arginine methyl esterNot Available
DB13431ProglumideNot Available
DB00129OrnithineUsed for nutritional supplementation, also for treating dietary shortage or imbalance. It has been claimed that ornithine improves athletic performance, has anabolic effects, has wound-healing effects, and is immuno-enhancing.
DB15199CiraparantagNot Available
DrugDrug NameTargetType
DB00123L-LysineHigh affinity cationic amino acid transporter 1target
DB00123L-LysineCationic amino acid transporter 4target
DB00123L-LysineCationic amino acid transporter 3target
DB00123L-LysineLow affinity cationic amino acid transporter 2target
DB00123L-LysineLysine--tRNA ligasetarget
DB00123L-LysineMonocarboxylate transporter 10transporter
DB00123L-LysineSolute carrier family 22 member 4transporter
DB00125L-ArginineCationic amino acid transporter 3target
DB00125L-ArginineArginine decarboxylasetarget
DB00125L-ArginineArgininosuccinate lyasetarget
DB00125L-ArginineNitric oxide synthase, inducibletarget
DB00125L-ArginineHigh affinity cationic amino acid transporter 1target
DB00125L-ArginineArginase-2, mitochondrialtarget
DB00125L-ArginineCationic amino acid transporter 4target
DB00125L-ArginineArgininosuccinate synthasetarget
DB00125L-ArginineNitric oxide synthase, endothelialtarget
DB00125L-ArginineSolute carrier family 22 member 5transporter
DB00125L-ArginineMonocarboxylate transporter 10transporter
DB00125L-ArginineSolute carrier family 22 member 4transporter
DB00130L-GlutamineCTP synthase 1target
DB00130L-GlutamineAmidophosphoribosyltransferasetarget
DB00130L-GlutamineGlutamine synthetasetarget
DB00130L-GlutamineMonocarboxylate transporter 10transporter
DB00130L-GlutamineCoagulation factor XIII A chainenzyme
DB00130L-GlutamineGlutaminase kidney isoform, mitochondrialenzyme
DB00130L-GlutamineGlutaminase liver isoform, mitochondrialenzyme
DB00130L-GlutamineProtein-glutamine gamma-glutamyltransferase 2enzyme
DB00130L-GlutamineProtein-glutamine gamma-glutamyltransferase 5enzyme
DB00130L-GlutamineProtein-glutamine gamma-glutamyltransferase 6enzyme
DB00130L-GlutamineProtein-glutamine gamma-glutamyltransferase Kenzyme
DB00130L-GlutamineProtein-glutamine gamma-glutamyltransferase 4enzyme
DB00130L-GlutamineProtein-glutamine gamma-glutamyltransferase Eenzyme
DB00130L-GlutamineProtein-glutamine gamma-glutamyltransferase Zenzyme
DB00130L-GlutamineSodium-coupled neutral amino acid transporter 3transporter
DB00130L-GlutamineNeutral amino acid transporter B(0)transporter
DB00130L-GlutamineGMP synthase [glutamine-hydrolyzing]enzyme
DB00130L-GlutamineAsparagine synthetase [glutamine-hydrolyzing]enzyme
DB00130L-GlutamineKynurenine--oxoglutarate transaminase 1enzyme
DB00130L-GlutaminePhosphoribosylformylglycinamidine synthaseenzyme
DB00130L-GlutamineGlutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrialenzyme
DB00130L-GlutamineGlutamine--fructose-6-phosphate aminotransferase [isomerizing] 2enzyme
DB00130L-GlutamineCAD proteinenzyme
DB00130L-GlutamineGlutamine--tRNA ligaseenzyme
DB00130L-GlutamineGlutamine-dependent NAD(+) synthetaseenzyme
DB00130L-GlutamineLarge neutral amino acids transporter small subunit 2transporter
DB00138CystineCystine/glutamate transportertarget
DB00138CystineCystinosintarget
DB00138CystineB(0,+)-type amino acid transporter 1target
DB00138CystineNeutral and basic amino acid transport protein rBATtarget
DB00138CystineMonocarboxylate transporter 10transporter
DB00155L-CitrullineNitric oxide synthase, endothelialtarget
DB00155L-CitrullineArgininosuccinate synthasetarget
DB00155L-CitrullineN(G),N(G)-dimethylarginine dimethylaminohydrolase 2target
DB00155L-CitrullineArgininosuccinate synthetase, isoform CRA_atarget
DB00155L-CitrullineN(G),N(G)-dimethylarginine dimethylaminohydrolase 1target
DB00155L-CitrullineOrnithine carbamoyltransferase, mitochondrialtarget
DB00155L-CitrullineNitric oxide synthase, braintarget
DB00155L-CitrullineNitric oxide synthase, inducibletarget
DB00155L-CitrullineProtein-arginine deiminase type-4target
DB00155L-CitrullineProtein-arginine deiminase type-6target
DB00155L-CitrullineProtein-arginine deiminase type-1target
DB00155L-CitrullineProtein-arginine deiminase type-3target
DB00155L-CitrullineProtein-arginine deiminase type-2target
DB00155L-CitrullineSolute carrier family 22 member 6transporter
DB00174AsparagineNeutral amino acid transporter B(0)target
DB00174AsparagineAsparagine synthetase [glutamine-hydrolyzing]target
DB00174AsparagineAsparagine--tRNA ligase, cytoplasmictarget
DB00174AsparagineIsoaspartyl peptidase/L-asparaginasetarget
DB00174AsparagineProbable asparagine--tRNA ligase, mitochondrialtarget
DB00174AsparagineSodium-coupled neutral amino acid transporter 3target
DB00174AsparagineMonocarboxylate transporter 10transporter
DB01686N,N-dimethylarginineNitric oxide synthase, inducibletarget
DB01686N,N-dimethylarginineNitric oxide synthase, endothelialtarget
DB02011N-(Phosphonoacetyl)-L-OrnithineOrnithine carbamoyltransferase, mitochondrialtarget
DB03144N-Omega-Hydroxy-L-ArginineNitric oxide synthase, endothelialtarget
DB03144N-Omega-Hydroxy-L-ArginineNitric oxide synthase oxygenasetarget
DB03144N-Omega-Hydroxy-L-ArginineNitric oxide synthase, inducibletarget
DB03144N-Omega-Hydroxy-L-ArginineArginase-1target
DB03144N-Omega-Hydroxy-L-ArginineNitric oxide synthase, braintarget
DB03251RWJ-51084Trypsin-1target
DB04167AceglutamideN-acylamino acid racemasetarget
DB04223NitroarginineNitric oxide synthase, endothelialtarget
DB04223NitroarginineNitric oxide synthase, braintarget
DB04527beta-HydroxyasparagineMannan-binding lectin serine protease 2target
DB04676DansyllysineIg alpha-2 chain C regiontarget
DB05668PalifosfamideDNA (cytosine-5)-methyltransferase 1target
DB06243EflornithineOrnithine decarboxylasetarget
DB11854AstodrimerEnvelope glycoprotein gp160target
DB00129OrnithineOrnithine aminotransferase, mitochondrialtarget
DB00129OrnithineOrnithine carbamoyltransferase, mitochondrialtarget
DB00129OrnithineArginase-1target
DB00129OrnithineOrnithine decarboxylase antizyme 1target
DB00129OrnithineLow affinity cationic amino acid transporter 2target
DB00129OrnithineMitochondrial ornithine transporter 2target
DB00129OrnithineCationic amino acid transporter 4target
DB00129OrnithineHigh affinity cationic amino acid transporter 1target
DB00129OrnithineArginase-2, mitochondrialtarget
DB00129OrnithineMitochondrial ornithine transporter 1target
DB00129OrnithineCationic amino acid transporter 3target
DB00129OrnithineOrnithine decarboxylase antizyme 2target
DB00129OrnithineGlycine amidinotransferase, mitochondrialtarget
DB00129OrnithineOrnithine decarboxylase antizyme 3target