Amino Acids, Basic

Name
Amino Acids, Basic
Accession Number
DBCAT000280
Description

Amino acids with side chains that are positively charged at physiological pH.

Drugs
DrugDrug Description
L-GlutamineAn amino acid commonly found as a component in total parenteral nutrition.
OrnithineAn amino acid commonly found as a component in total parenteral nutrition.
LysineAn amino acid commonly found as a component of total parenteral nutrition.
D-GlutamineA non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of...
ArginineAn amino acid commonly found as a component of total parenteral nutrition.
AsparagineUsed for nutritional supplementation, also for treating dietary shortage or imbalance.
N-(Phosphonoacetyl)-L-OrnithineNot Available
N(G)-IminoethylornithineNot Available
TalotrexinInvestigated for use/treatment in solid tumors, lung cancer, leukemia (unspecified), and leukemia (lymphoid).
EflornithineAn ornithine decarboxylase inhibitor used to prevent relapse of high-risk neuroblastoma in pediatric and adult patients
FasitibantFasitibant is under investigation in clinical trial NCT02205814 (Fasitibant Intra-articular Injection in Patients With Symptomatic Osteoarthritis of the Knee).
ArgatrobanA synthetic direct thrombin inhibitor used for the prevention and treatment of thrombosis related to heparin use.
KetoprofenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
N,N-dimethylarginineAsymmetric dimethylarginine (ADMA) is a naturally occurring chemical found in blood plasma. It is a metabolic by-product of continual protein modification processes in the cytoplasm of all human cells which...
Epsilon-N-methyllysineNot Available
N-acetyl-L-arginineNot Available
Symmetric dimethylarginineNot Available
IsoglutamineNot Available
N(5)-[(hydroxyamino)(imino)methyl]-L-ornithineNot Available
RWJ-51084Not Available
L-homoarginineNot Available
TrimethyllysineNot Available
AceglutamideNot Available
N(2)-(2-carboxyethyl)-L-arginineNot Available
L-SaccharopineNot Available
NitroarginineAn inhibitor of nitric oxide synthetase which has been shown to prevent glutamate toxicity. Nitroarginine has been experimentally tested for its ability to prevent ammonia toxicity and ammonia-induced alterations in...
beta-HydroxyasparagineNot Available
DansyllysineNot Available
PalifosfamideInvestigated for use/treatment in cancer/tumors (unspecified), lymphoma (unspecified), and sarcoma.
ClonixinAn NSAID used to relieve pain associated with arthritis, migraines, and various soft tissue disorders.
TilarginineTilarginine has been investigated for the basic science, treatment, and diagnostic of Obesity, Type 2 Diabetes, Ocular Physiology, and Regional Blood Flow.
AstodrimerAstodrimer has been used in trials studying the treatment and prevention of Bacterial Vaginosis. It is a lysine-based dendrimer with naphthalene disulfonic acid surface groups.
N-omega-nitro-L-arginine methyl esterL-NAME has been investigated for the treatment of Hypotension and Spinal Cord Injury.
ProglumideNot Annotated
Piflufolastat F 18A radiopharmaceutical diagnostic agent used with PET to image PSMA-positive lesions for the diagnosis of metastatic or recurrent prostate cancer.
CiraparantagCiraparantag is under investigation in clinical trial NCT01826266 (Effects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of Edoxaban).
Arginine aspartateAn ingredient in products indicated to treat exhaustion during stress, endurance sports, or in the elderly.
PhenylacetylglutamineNot Annotated
L-arginineNot Annotated
HiltonolNot Available
Heme arginateNot Available
NacystelynNot Annotated
Drugs & Drug Targets
DrugTargetType
L-GlutamineCTP synthase 1target
L-GlutamineAmidophosphoribosyltransferasetarget
L-GlutamineGlutamine synthetasetarget
L-GlutamineMonocarboxylate transporter 10transporter
L-GlutamineCoagulation factor XIII A chainenzyme
L-GlutamineGlutaminase kidney isoform, mitochondrialenzyme
L-GlutamineGlutaminase liver isoform, mitochondrialenzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 2enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 5enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 6enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase Kenzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase 4enzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase Eenzyme
L-GlutamineProtein-glutamine gamma-glutamyltransferase Zenzyme
L-GlutamineSodium-coupled neutral amino acid transporter 3transporter
L-GlutamineNeutral amino acid transporter B(0)transporter
L-GlutamineGMP synthase [glutamine-hydrolyzing]enzyme
L-GlutamineAsparagine synthetase [glutamine-hydrolyzing]enzyme
L-GlutamineKynurenine--oxoglutarate transaminase 1enzyme
L-GlutaminePhosphoribosylformylglycinamidine synthaseenzyme
L-GlutamineGlutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrialenzyme
L-GlutamineGlutamine--fructose-6-phosphate aminotransferase [isomerizing] 2enzyme
L-GlutamineCAD proteinenzyme
L-GlutamineGlutamine--tRNA ligaseenzyme
L-GlutamineGlutamine-dependent NAD(+) synthetaseenzyme
L-GlutamineLarge neutral amino acids transporter small subunit 2transporter
L-GlutamineSodium-coupled neutral amino acid transporter 1transporter
L-GlutamineSodium-coupled neutral amino acid transporter 2transporter
L-GlutamineSodium- and chloride-dependent neutral and basic amino acid transporter B(0+)transporter
L-GlutamineY+L amino acid transporter 1transporter
L-GlutamineY+L amino acid transporter 2transporter
L-GlutamineLarge neutral amino acids transporter small subunit 1transporter
L-GlutamineB(0,+)-type amino acid transporter 1transporter
OrnithineOrnithine aminotransferase, mitochondrialtarget
OrnithineOrnithine carbamoyltransferase, mitochondrialtarget
OrnithineArginase-1target
OrnithineOrnithine decarboxylase antizyme 1target
OrnithineLow affinity cationic amino acid transporter 2target
OrnithineMitochondrial ornithine transporter 2target
OrnithineHigh affinity cationic amino acid transporter 1target
OrnithineArginase-2, mitochondrialtarget
OrnithineMitochondrial ornithine transporter 1target
OrnithineGlycine amidinotransferase, mitochondrialtarget
LysineHigh affinity cationic amino acid transporter 1target
LysineCationic amino acid transporter 4target
LysineCationic amino acid transporter 3target
LysineLow affinity cationic amino acid transporter 2target
LysineLysine--tRNA ligasetarget
LysineMonocarboxylate transporter 10transporter
LysineSolute carrier family 22 member 4transporter
D-GlutamineGlutamate racemasetarget
ArginineCationic amino acid transporter 3target
ArginineArginine decarboxylasetarget
ArginineArgininosuccinate lyasetarget
ArginineNitric oxide synthase, inducibletarget
ArginineHigh affinity cationic amino acid transporter 1target
ArginineArginase-2, mitochondrialtarget
ArginineCationic amino acid transporter 4target
ArginineArgininosuccinate synthasetarget
ArginineNitric oxide synthase, endothelialtarget
ArginineSolute carrier family 22 member 5transporter
ArginineMonocarboxylate transporter 10transporter
ArginineSolute carrier family 22 member 4transporter
AsparagineNeutral amino acid transporter B(0)target
AsparagineAsparagine synthetase [glutamine-hydrolyzing]target
AsparagineAsparagine--tRNA ligase, cytoplasmictarget
AsparagineIsoaspartyl peptidase/L-asparaginasetarget
AsparagineProbable asparagine--tRNA ligase, mitochondrialtarget
AsparagineMonocarboxylate transporter 10transporter
AsparagineSodium-coupled neutral amino acid transporterstarget
N-(Phosphonoacetyl)-L-OrnithineOrnithine carbamoyltransferase, mitochondrialtarget
N(G)-IminoethylornithineNitric oxide synthase, endothelialtarget
EflornithineOrnithine decarboxylasetarget
ArgatrobanProthrombintarget
ArgatrobanCytochrome P450 3A4enzyme
ArgatrobanCytochrome P450 3A5enzyme
ArgatrobanSerum albumincarrier
Argatrobanalpha1-acid glycoproteincarrier
KetoprofenProstaglandin G/H synthase 1target
KetoprofenProstaglandin G/H synthase 2target
KetoprofenC-X-C chemokine receptor type 1target
KetoprofenSerum albumincarrier
KetoprofenMultidrug resistance-associated protein 4transporter
KetoprofenSolute carrier organic anion transporter family member 1A2transporter
KetoprofenSolute carrier family 22 member 6transporter
KetoprofenSolute carrier family 22 member 8transporter
KetoprofenSolute carrier family 22 member 11transporter
KetoprofenSolute carrier family 22 member 7transporter
KetoprofenCytochrome P450 2C9enzyme
KetoprofenCytochrome P450 2C8enzyme
KetoprofenUDP-glucuronosyltransferase 1-1enzyme
N,N-dimethylarginineNitric oxide synthase, inducibletarget
N,N-dimethylarginineNitric oxide synthase, endothelialtarget
N-acetyl-L-arginineClavaminate synthase 1target
Symmetric dimethylarginineHaloalkane dehalogenasetarget
IsoglutamineATP synthase subunit btarget
N(5)-[(hydroxyamino)(imino)methyl]-L-ornithineNitric oxide synthase, endothelialtarget
N(5)-[(hydroxyamino)(imino)methyl]-L-ornithineNitric oxide synthase oxygenasetarget
N(5)-[(hydroxyamino)(imino)methyl]-L-ornithineNitric oxide synthase, inducibletarget
N(5)-[(hydroxyamino)(imino)methyl]-L-ornithineArginase-1target
N(5)-[(hydroxyamino)(imino)methyl]-L-ornithineNitric oxide synthase, braintarget
RWJ-51084Trypsin-1target
L-homoarginineNitric oxide synthase, endothelialtarget
TrimethyllysineCytochrome ctarget
TrimethyllysineCalmodulintarget
AceglutamideN-acylamino acid racemasetarget
L-SaccharopineAlpha-aminoadipic semialdehyde synthase, mitochondrialtarget
NitroarginineNitric oxide synthase, endothelialtarget
NitroarginineNitric oxide synthase, braintarget
beta-HydroxyasparagineMannan-binding lectin serine protease 2target
DansyllysineIg alpha-2 chain C regiontarget
PalifosfamideDNA (cytosine-5)-methyltransferase 1target
AstodrimerEnvelope glycoprotein gp160target
Piflufolastat F 18Glutamate carboxypeptidase 2target