Dietary Fats, Unsaturated

Unsaturated fats or oils used in foods or as a food.
DrugDrug NameDrug Description
DB00132alpha-Linolenic acidA polyunsaturated omega-3 fatty acid found in many supplements.
DB00159IcosapentA polyunsaturated fatty acid, usually found in fish oils, that is used in many supplements.
DB08887Icosapent ethylAn ethyl ester of eicosapentaenoic acid (EPA) that reduces synthesis and enhances clearance of triglycerides that is used to treat patients with severe hypertriglyceridemia.
DB09422Soybean oilAn oil used as a source of calories and essential fatty acids in selected patients for total parenteral nutrition (TPN) therapy and prevention of essential fatty acid deficiency.
DB09446Safflower oilNo approved therapeutic indications.
DB09539Omega-3-acid ethyl estersA mixture of fatty acids used as an adjunct to diet to reduce triglyceride (TG) levels in adult patients with severe hypertriglyceridemia.
DB09567Olive oilFor use in adults as a source of calories and fatty acids in total parenteral nutrition [FDA Label]. Sometimes used as an additive in cosmetic products.
DB11133Omega-3 fatty acidsAn ingredient found in a variety of supplements and vitamins.
DB11172Sesame oilSesame oil is a commonly used vegetable oil in Asia and flavoring enhancer in various culinary practices. It is extracted from sesame seeds and contains linoleic acid, oleic acid, palmitic...
DB11238Borage oilBorage oil, or borage seed oil, is a rich source of gamma-linolenic acid (GLA) that is obtained from the seeds of the Borago officinalis (borage). Borage oil is used as...
DB11321Cod liver oilAn ingredient found in a variety of nutritional products.
DB11358Evening primrose oilEvening primrose oil is used as part of over-the-counter dietary supplements. It is also used for the treatment of systemic inflammatory diseases and for women's health conditions such as cyclical...
DB13105Resolvin E1Resolvin E1 (RX 10001) is under investigation in clinical trial NCT00941018 (Single and Multiple Ascending Oral Dose Study of Resolvin E1 in Healthy Volunteers).
DB03756DoconexentAn omega 3 fatty acid used in a variety of nutritional supplements to support central nervous system and cardiovascular health.
DrugDrug NameTargetType
DB00132alpha-Linolenic acidFatty acid-binding protein, braincarrier
DB00132alpha-Linolenic acidFatty acid desaturase 1target
DB00132alpha-Linolenic acidFatty acid desaturase 2target
DB00132alpha-Linolenic acidSodium/calcium exchanger 1target
DB00132alpha-Linolenic acidTransient receptor potential cation channel subfamily V member 1target
DB00132alpha-Linolenic acidElongation of very long chain fatty acids protein 4target
DB00132alpha-Linolenic acidPeroxisome proliferator-activated receptor alphatarget
DB00132alpha-Linolenic acidBile acid receptortarget
DB00132alpha-Linolenic acidPeroxisome proliferator-activated receptor deltatarget
DB00132alpha-Linolenic acidPeroxisome proliferator-activated receptor gammatarget
DB00132alpha-Linolenic acidRetinoic acid receptor RXR-alphatarget
DB00159IcosapentProstaglandin G/H synthase 2target
DB00159IcosapentProstaglandin G/H synthase 1target
DB00159IcosapentFree fatty acid receptor 1target
DB00159IcosapentFatty acid-binding protein, braincarrier
DB00159IcosapentFatty acid desaturase 1target
DB00159IcosapentLong-chain-fatty-acid--CoA ligase 4target
DB00159IcosapentLong-chain-fatty-acid--CoA ligase 3target
DB00159IcosapentSodium/calcium exchanger 1target
DB00159IcosapentPeroxisome proliferator-activated receptor gammatarget
DB00159IcosapentPeroxisome proliferator-activated receptor deltatarget
DB00159IcosapentTransient receptor potential cation channel subfamily V member 1target
DB00159IcosapentPeroxisome proliferator-activated receptor alphatarget
DB00159IcosapentSerum albumincarrier
DB09422Soybean oilPeroxisome proliferator-activated receptor alphatarget
DB09539Omega-3-acid ethyl estersSterol O-acyltransferase 1enzyme
DB09539Omega-3-acid ethyl estersSterol regulatory element-binding protein 1target
DB11133Omega-3 fatty acidsPeroxisome proliferator-activated receptor gammatarget
DB11133Omega-3 fatty acidsProstaglandin G/H synthase 2enzyme
DB11133Omega-3 fatty acidsArachidonate 5-lipoxygenaseenzyme
DB11133Omega-3 fatty acidsPeroxisome proliferator-activated receptor alphatarget
DB11133Omega-3 fatty acidsSterol regulatory element-binding protein 1target
DB11358Evening primrose oilElongation of very long chain fatty acids protein 5enzyme
DB11358Evening primrose oilFatty acid desaturase 1enzyme
DB11358Evening primrose oilFatty acid desaturase 2enzyme
DB03756DoconexentFatty acid-binding protein, braincarrier
DB03756DoconexentCytochrome P450 2C9enzyme
DB03756DoconexentPeroxisome proliferator-activated receptor alphatarget
DB03756DoconexentPeroxisome proliferator-activated receptor gammatarget
DB03756DoconexentSterol regulatory element-binding protein 1target
DB03756DoconexentRetinoic acid receptor RXR-alphatarget
DB03756DoconexentRetinoic acid receptor RXR-betatarget
DB03756DoconexentRetinoic acid receptor RXR-gammatarget