The vapor state of matter; nonelastic fluids in which the molecules are in free movement and their mean positions far apart. Gases tend to expand indefinitely, to diffuse and mix readily with other gases, to have definite relations of volume, temperature, and pressure, and to condense or liquefy at low temperatures or under sufficient pressure. (Grant & Hackh's Chemical Dictionary, 5th ed)
DrugDrug NameDrug Indication
DB00138CystineIt has been claimed that L-cysteine has anti-inflammatory properties, that it can protect against various toxins, and that it might be helpful in osteoarthritis and rheumatoid arthritis. More research will have to be done before L-cysteine can be indicated for any of these conditions. Research to date has mostly been in animal models.
DB00435Nitric OxideFor the treatment of term and near-term (>34 weeks) neonates with hypoxic respiratory failure
DB00822DisulfiramFor the treatment and management of chronic alcoholism
DB024862-Hydroxyethyl DisulfideNot Available
DB04570LatamoxefLatamoxef is an oxacephem antibiotic usually grouped with the cephalosporins. It is used to treat bacterial infections. Latamoxef is primarily indicated in conditions like Bone and joint infection, GI infections, Gynecological infections, Meningitis, Respiratory tract infections, Septicaemia, Skin infections, Soft tissue infections, UTI.
DB06690Nitrous oxideNot Available
DB076234,4'-DIPYRIDYL DISULFIDENot Available
DB09068VortioxetineVortioxetine is indicated for the treatment of major depressive disorder (MDD).
DB09140OxygenOxygen therapy in clinical settings is used across diverse specialties, including various types of anoxia, hypoxia or dyspnea and any other disease states and conditions that reduce the efficiency of gas exchange and oxygen consumption such as respiratory illnesses, trauma, poisonings and drug overdoses. Oxygen therapy tries to achieve hyperoxia [L745] to reduce the extent of hypoxia-induced tissue damage and malfunction.
DB09152NitrogenLiquid nitrogen is used mainly as a cryogenic agent for the treatment of various benign and malignant skin lesions.
DB09155HeliumFor use in patients who are not getting enough oxygen into their blood due to blockages in the lungs from pathological conditions or injuries. Suggested potential benefit in upper airway obstruction, in severe asthma, and in exacerbations of COPD/COLD. Helium may be used in place of carbon monoxide during laparoscopic surgeries as it lowers the risk of developing respiratory acidosis in selected patients.
DB09157Carbon dioxideCarbon dioxide is commonly used as an insufflation gas for minimal invasive surgery (laparoscopy, endoscopy, and arthroscopy) to enlarge and stabilize body cavities to provide better visibility of the surgical area. It has been used also in cryotherapy and as respiratory stimulant before and after anesthesia. It could be used also in expansion of blood vessels if required, to increase carbon dioxide level after rapid breathing, and to stimulate breathing after a period of nonbreathing.
DB11104Sulfur hexafluorideEchocardiography: Sulfur hexafluoride is indicated for use in adult patients with suboptimal echocardiograms to opacify the left ventricular chamber and to improve the delineation of the left ventricularendocardial border. Ultrasonography of the Liver: Sulfur hexafluoride is indicated for use with ultrasound of the liver in adult and pediatric patients to characterize focal liver lesions.
DB11109ChlorineNot Available
DB11118Ammonia- Indicated for use as a smelling salt to treat or prevent fainting. - (when radiolabelled) Indicated for diagnostic PET imaging of the myocardium under rest or pharmacologic stress conditions to evaluate myocardial perfusion in patients with suspected or existing coronary artery disease [FDA Label].
DB11159Sodium sulfideNot Available
DB11588Carbon monoxideUsed as a marker of respiratory status in spirometry tests [L2557], [F4]. Food additive for pigment fixation in meat [L2531].
DB11589NeonIndicated for use as a diagnostic tracer gas in pulmonary function tests.
DB11645PF-4191834Not Available
DB12109CPI-613Not Available
DB12237GW-274150Not Available
DB12354ImrecoxibNot Available
DB12510OzoneNot Available
DB13107QGC-001Not Available
DB13344Mercuric amidochlorideNot Available
DB13356MesulfenNot Available
DB13453XenonNot Available
DB13473Antimony pentasulfideNot Available
DB13712DixanthogenNot Available
DB05389TetrachlorodecaoxideInvestigated for use/treatment in acquired immune deficiency syndrome (AIDS) and aids-related infections, cancer/tumors (unspecified), HIV infection, and inflammatory disorders (unspecified).
DB05448PX-12Investigated for use/treatment in cancer/tumors (unspecified), gastric cancer, and pancreatic cancer.
DB15127HydrogenNot Available
DrugDrug NameTargetType
DB00138CystineCystine/glutamate transportertarget
DB00138CystineB(0,+)-type amino acid transporter 1target
DB00138CystineNeutral and basic amino acid transport protein rBATtarget
DB00138CystineMonocarboxylate transporter 10transporter
DB00435Nitric OxideGuanylate cyclase soluble subunit alpha-2target
DB00435Nitric OxideAldehyde dehydrogenase, mitochondrialenzyme
DB00435Nitric OxideCytochrome P450 1A2enzyme
DB00435Nitric OxideCytochrome P450 2B6enzyme
DB00435Nitric OxideCytochrome P450 3A4enzyme
DB00435Nitric OxideMetallothionein-1Atarget
DB00435Nitric OxideIndoleamine 2,3-dioxygenase 1target
DB00822DisulfiramAldehyde dehydrogenase, mitochondrialtarget
DB00822DisulfiramCytochrome P450 2E1enzyme
DB00822DisulfiramDopamine beta-hydroxylasetarget
DB00822DisulfiramCytochrome P450 3A4enzyme
DB00822DisulfiramCytochrome P450 3A5enzyme
DB00822DisulfiramBile salt export pumptransporter
DB024862-Hydroxyethyl DisulfideLysozymetarget
DB024862-Hydroxyethyl DisulfideGlutathione S-transferase A1target
DB024862-Hydroxyethyl DisulfideGlutathione S-transferase A1enzyme
DB04570LatamoxefPenicillin-binding protein 3target
DB04570LatamoxefPenicillin-binding protein 1Atarget
DB04570LatamoxefPenicillin-binding protein 1Btarget
DB04570LatamoxefD-alanyl-D-alanine carboxypeptidase DacBtarget
DB076234,4'-DIPYRIDYL DISULFIDECytochrome P450 2A6target
DB09068VortioxetineSodium-dependent serotonin transportertarget
DB09068Vortioxetine5-hydroxytryptamine receptor 3Atarget
DB09068Vortioxetine5-hydroxytryptamine receptor 7target
DB09068Vortioxetine5-hydroxytryptamine receptor 1Btarget
DB09068Vortioxetine5-hydroxytryptamine receptor 1Atarget
DB09068VortioxetineBeta-1 adrenergic receptortarget
DB09068Vortioxetinesolute carrier family 6 member 2target
DB09068VortioxetineCytochrome P450 2D6enzyme
DB09068VortioxetineCytochrome P450 3A4enzyme
DB09068VortioxetineCytochrome P450 3A5enzyme
DB09068VortioxetineCytochrome P450 2C19enzyme
DB09068VortioxetineCytochrome P450 2C9enzyme
DB09068VortioxetineCytochrome P450 2A6enzyme
DB09068VortioxetineCytochrome P450 2C8enzyme
DB09068VortioxetineCytochrome P450 2B6enzyme
DB09140OxygenNADPH oxidase 1target
DB09140OxygenCytochrome c oxidase subunit 1target
DB09140OxygenHemoglobin subunit alphatarget
DB09140OxygenHemoglobin subunit betatarget
DB11118AmmoniaGlutaminase liver isoform, mitochondrialenzyme
DB11118AmmoniaGlutamine synthetaseenzyme
DB11118AmmoniaCarbamoyl-phosphate synthase [ammonia], mitochondrialenzyme
DB11588Carbon monoxideMyoglobintarget
DB11588Carbon monoxideAlveolar cellstarget
DB05389TetrachlorodecaoxideMacrophage erythroblast attachertarget
DB05389TetrachlorodecaoxideScavenger receptor cysteine-rich type 1 protein M130target
DB05448PX-12Thioredoxin reductase 1, cytoplasmictarget