Hexosamines

Name
Hexosamines
Accession Number
DBCAT000337
Description

A class of organic compounds composed of carbon, hydrogen, and oxygen in a ratio of Cn(H2O)n. The largest class of organic compounds, including STARCH; GLYCOGEN; CELLULOSE; POLYSACCHARIDES; and simple MONOSACCHARIDES.

Drugs
DrugDrug Description
GlucosamineA common ingredient in nutritional supplements used for the relief of joint pain.
MeglumineAn amino sugar found in iodinated contrast media.
N-AcetylglucosamineFor the treatment and prevention of osteoarthritis, by itself or in combination with chondroitin sulfate.
DiatrizoateAn injected contrast agent used in radiology.
Gadobenic acidA gadolinium-based contrast agent (GBCA) used with contrasted magnetic resonance imaging (MRI) to detect and visualize lesions and abnormal vascularity.
Glucosamine 6-PhosphateNot Available
Glucosamine 4-PhosphateNot Available
Glucosamine 1-PhosphateNot Available
DuvoglustatAn alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
N-Acetyl-glucosamine thiazolineN-Acetyl-glucosamine thiazoline (NAG-thiazoline) is an analog of the oxazolinium bicyclic intermediate leading from N-acetylglucosamine to 1,6-anhydro-N-acetylmuramic acid.
AllosamizolineNot Available
AllosamidinAllosamidin exhibits extremely potent inhibitory activity against chitinases from a number of sources, particularly from Candida albicans, and can be utilized as potent antifungal agent.
Gadoteric acidA gadolinium-based contrast agent (GBCA) used with contrasted magnetic resonance imaging (MRI) to detect and visualize lesions and abnormal vascularity.
Iothalamic acidA diagnostic contrast agent used in various medical imaging procedures, such as angiography, arthrography, and computed tomographic scans.
Ioxitalamic acidA contrast agent used for CT scans of the abdomen and pelvis.
Meglumine antimoniateNot Annotated
Iocarmic acidNot Annotated
FitusiranFitusiran is under investigation in clinical trial NCT02554773 (An Open-label Extension Study of an Investigational Drug, ALN-AT3SC, in Patients With Moderate or Severe Hemophilia A or B).
GivosiranA 5-aminolevulinic acid synthase-directed small interfering RNA (siRNA) used in the prophylaxis of acute hepatic porphyria.
Drugs & Drug Targets
DrugTargetType
GlucosamineInterferon gammatarget
GlucosamineSolute carrier family 2, facilitated glucose transporter member 2transporter
GlucosamineSolute carrier family 2, facilitated glucose transporter member 1transporter
GlucosamineSolute carrier family 2, facilitated glucose transporter member 4transporter
GlucosamineSolute carrier family 2, facilitated glucose transporter member 3transporter
GlucosamineTranscription factor p65target
N-AcetylglucosamineAlpha-N-acetylglucosaminidasetarget
N-AcetylglucosamineN-acylglucosamine 2-epimerasetarget
N-AcetylglucosamineBeta-1,4-galactosyltransferase 1target
N-AcetylglucosamineBeta-1,4-galactosyltransferase 4target
N-AcetylglucosamineN-acetyl-D-glucosamine kinasetarget
N-AcetylglucosamineN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidasetarget
Gadobenic acidSerum albumincarrier
Gadobenic acidCanalicular multispecific organic anion transporter 1transporter
Glucosamine 6-PhosphateGlutamine--fructose-6-phosphate aminotransferase [isomerizing]target
Glucosamine 6-PhosphateN-acetylglucosamine-6-phosphate deacetylasetarget
Glucosamine 4-PhosphateFerrichrome-iron receptortarget
Glucosamine 1-PhosphateFerrichrome-iron receptortarget
DuvoglustatCyclomaltodextrin glucanotransferasetarget
DuvoglustatBeta-glucosidase Atarget
DuvoglustatEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasetarget
DuvoglustatMannosyl-oligosaccharide alpha-1,2-mannosidasetarget
DuvoglustatXylose isomerasetarget
N-Acetyl-glucosamine thiazolineBeta-hexosaminidase subunit betatarget
N-Acetyl-glucosamine thiazolineB-N-acetylhexosaminidasetarget
AllosamizolineChitotriosidase-1target
AllosamizolineChitinase Btarget
AllosamizolineChitinase Atarget
AllosamidinChitinase Btarget
AllosamidinChitinase Atarget
GivosiranALAS1 mRNAtarget