Amino Sugars

Name
Amino Sugars
Accession Number
DBCAT000338
Description

SUGARS containing an amino group. GLYCOSYLATION of other compounds with these amino sugars results in AMINOGLYCOSIDES.

Drugs
DrugDrug Description
GlucosamineA common ingredient in nutritional supplements used for the relief of joint pain.
N-AcetylglucosamineFor the treatment and prevention of osteoarthritis, by itself or in combination with chondroitin sulfate.
DiatrizoateAn injected contrast agent used in radiology.
ZanamivirA neuraminidase inhibitor used to treat influenza A and B.
Gadobenic acidA gadolinium-based contrast agent (GBCA) used with contrasted magnetic resonance imaging (MRI) to detect and visualize lesions and abnormal vascularity.
Glucosamine 6-PhosphateNot Available
Glucosamine 4-PhosphateNot Available
Glucosamine 1-PhosphateNot Available
DuvoglustatAn alpha-glucosidase inhibitor with antiviral action. Derivatives of deoxynojirimycin may have anti-HIV activity.
N-Acetyl-glucosamine thiazolineN-Acetyl-glucosamine thiazoline (NAG-thiazoline) is an analog of the oxazolinium bicyclic intermediate leading from N-acetylglucosamine to 1,6-anhydro-N-acetylmuramic acid.
2-deoxy-2,3-dehydro-N-acetylneuraminic acidNot Available
AllosamizolineNot Available
AllosamidinAllosamidin exhibits extremely potent inhibitory activity against chitinases from a number of sources, particularly from Candida albicans, and can be utilized as potent antifungal agent.
Iothalamic acidA diagnostic contrast agent used in various medical imaging procedures, such as angiography, arthrography, and computed tomographic scans.
MeglumineAn amino sugar found in iodinated contrast media.
Laninamivir octanoateLaninamivir octanoate has been used in trials studying the treatment of Asthma.
N-acetylmannosamineN-acetylmannosamine is under investigation for the other of GNE Myopathy.
LaninamivirLaninamivir has been used in trials studying the treatment of Influenza.
Ioxitalamic acidA contrast agent used for CT scans of the abdomen and pelvis.
MifamurtideA muramyl dipeptide derivative used to treat high grade, resectable, non-metastatic osteosarcoma after surgical resection.
Meglumine antimoniateNot Annotated
Iocarmic acidNot Annotated
ColeneuramideColeneuramide is under investigation in clinical trial NCT00307749 (Safety and Efficacy of MCC-257 in the Treatment of Diabetic Polyneuropathy).
FitusiranFitusiran is under investigation in clinical trial NCT02554773 (An Open-label Extension Study of an Investigational Drug, ALN-AT3SC, in Patients With Moderate or Severe Hemophilia A or B).
GivosiranA 5-aminolevulinic acid synthase-directed small interfering RNA (siRNA) used in the prophylaxis of acute hepatic porphyria.
Gadoteric acidA gadolinium-based contrast agent (GBCA) used with contrasted magnetic resonance imaging (MRI) to detect and visualize lesions and abnormal vascularity.
Drugs & Drug Targets
DrugTargetType
GlucosamineInterferon gammatarget
GlucosamineSolute carrier family 2, facilitated glucose transporter member 2transporter
GlucosamineSolute carrier family 2, facilitated glucose transporter member 1transporter
GlucosamineSolute carrier family 2, facilitated glucose transporter member 4transporter
GlucosamineSolute carrier family 2, facilitated glucose transporter member 3transporter
GlucosamineTranscription factor p65target
N-AcetylglucosamineAlpha-N-acetylglucosaminidasetarget
N-AcetylglucosamineN-acylglucosamine 2-epimerasetarget
N-AcetylglucosamineBeta-1,4-galactosyltransferase 1target
N-AcetylglucosamineBeta-1,4-galactosyltransferase 4target
N-AcetylglucosamineN-acetyl-D-glucosamine kinasetarget
N-AcetylglucosamineN-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidasetarget
ZanamivirNeuraminidasetarget
ZanamivirNeuraminidasetarget
ZanamivirSialidase-2target
Gadobenic acidSerum albumincarrier
Gadobenic acidCanalicular multispecific organic anion transporter 1transporter
Glucosamine 6-PhosphateGlutamine--fructose-6-phosphate aminotransferase [isomerizing]target
Glucosamine 6-PhosphateN-acetylglucosamine-6-phosphate deacetylasetarget
Glucosamine 4-PhosphateFerrichrome-iron receptortarget
Glucosamine 1-PhosphateFerrichrome-iron receptortarget
DuvoglustatCyclomaltodextrin glucanotransferasetarget
DuvoglustatBeta-glucosidase Atarget
DuvoglustatEndoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidasetarget
DuvoglustatMannosyl-oligosaccharide alpha-1,2-mannosidasetarget
DuvoglustatXylose isomerasetarget
N-Acetyl-glucosamine thiazolineBeta-hexosaminidase subunit betatarget
N-Acetyl-glucosamine thiazolineB-N-acetylhexosaminidasetarget
2-deoxy-2,3-dehydro-N-acetylneuraminic acidHemagglutinin-neuraminidasetarget
2-deoxy-2,3-dehydro-N-acetylneuraminic acidSialidasetarget
2-deoxy-2,3-dehydro-N-acetylneuraminic acidNeuraminidasetarget
2-deoxy-2,3-dehydro-N-acetylneuraminic acidHemagglutinin-neuraminidasetarget
2-deoxy-2,3-dehydro-N-acetylneuraminic acidSialidase-2target
AllosamizolineChitotriosidase-1target
AllosamizolineChitinase Btarget
AllosamizolineChitinase Atarget
AllosamidinChitinase Btarget
AllosamidinChitinase Atarget
MifamurtideToll-like receptor 4target
MifamurtideNucleotide-binding oligomerization domain-containing protein 2target
GivosiranALAS1 mRNAtarget