Pyrimidines

Name
Pyrimidines
Accession Number
DBCAT000349
Description

A family of 6-membered heterocyclic compounds occurring in nature in a wide variety of forms. They include several nucleic acid constituents (CYTOSINE; THYMINE; and URACIL) and form the basic structure of the barbiturates.

Drugs
DrugDrug Description
ThiamineA vitamin used to correct vitamin B1 deficiency.
PyrimethamineAn antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria.
ButabarbitalA barbiturate drug used as a sedative and hypnotic.
ButalbitalA barbiturate drug used for symptomatic treatment of tension-type headache in various combinations with acetaminophen, aspirin, caffeine, and codeine.
IdoxuridineA pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis.
TalbutalFor use as a sedative and hypnotic.
PentobarbitalA barbiturate drug used to induce sleep, cause sedation, and control certain types of seizures.
FloxuridineAn antimetabolite used as palliative management for liver metastases of gastrointestinal malignancy.
MinoxidilAn antihypertensive vasodilating agent used for resistant hypertension that is symptomatic or has caused end organ damage.
CidofovirAn antiviral agent used to treat Cytomegalovirus (CMV) retinitis in patients with AIDS.
SecobarbitalA barbiturate used for the short-term treatment of insomnia.
TrifluridineA nucleoside metabolic inhibitor used to treat keratoconjunctivitis and epithelial keratitis caused by simplex virus, and as a part of chemotherapy for certain types of metastatic gastrointestinal cancers.
TrimethoprimAn antifolate antibiotic often used in combination with sulfamethoxazole to treat a number of infections, including those of the urinary tract, respiratory tract, and gastrointestinal tract.
GemcitabineA nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer.
MetharbitalMetharbital is used for the treatment of epilepsy.
MethohexitalAn anesthetic used to induce deep sedation.
ChlordiazepoxideA benzodiazepine used to treat the withdrawal symptoms of acute alcoholism, to treat preoperative anxiety, and to treat anxiety over a short term period.
BuspironeAn anxiolytic agent used for short-term treatment of generalized anxiety and second-line treatment of depression.
ZidovudineA dideoxynucleoside used in the treatment of HIV infection.
FluorouracilA pyrimidine analog used to treat basal cell carcinomas, and as an injection in palliative cancer treatment.
PropylthiouracilA thiourea antithyroid agent used to treat hyperthyroidism.
PentostatinAn adenosine deaminase inhibitor used to treat hairy cell leukemia.
ThiopentalA barbiturate used to induce general anesthesia, treat convulsions, and reduce intracranial pressure.
ImatinibA tyrosine kinase inhibitor used to treat a number of leukemias, myelodysplastic/myeloproliferative disease, systemic mastocytosis, hypereosinophilic syndrome, dermatofibrosarcoma protuberans, and gastrointestinal stromal tumors.
StavudineA dideoxynucleoside used in the treatment of HIV infection.
LamivudineA reverse transcriptase inhibitor used to treat HIV and hepatitis B infections.
RisperidoneA second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression.
Uracil mustardUsed for its antineoplastic properties.
PrimidoneAn antiepileptic used to treat grand mal, psychomotor, and focal epileptic seizures.
MethylphenobarbitalFor the relief of anxiety, tension, and apprehension, also used as an anticonvulsant for the treatment of epilepsy.
EmtricitabineA nucleoside reverse transcriptase inhibitor used for the treatment and prophylaxis of HIV.
PemirolastA medication used to treat allergies such as hay fever and allergic conjunctivitis.
AzacitidineA pyrimidine nucleoside analogue used to treat certain subtypes of myelodysplastic syndrome.
ZalcitabineA dideoxynucleoside used to treat HIV.
DipyridamoleA phosphodiesterase inhibitor used to prevent postoperative thromboembolic events.
CytarabineA pyrimidine nucleoside analogue used to treat acute non-lymphocytic leukemia, lymphocytic leukemia, and the blast phase of chronic myelocytic leukemia.
RosuvastatinAn HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
FlucytosineAn antifungal indicated only to treat severe infections throughout the body caused by susceptible strains of Candida or Cryptococcus.
CapecitabineA nucleoside metabolic inhibitor indicated to treat colon, colorectal and breast cancer.
ThiamylalUsed for the production of complete anaesthesia of short duration, for the induction of general anaesthesia, and for inducing a hypnotic state.
PhenobarbitalA long-lasting barbiturate and anticonvulsant used in the treatment of all types of seizures, except for absent seizures.
DasatinibA tyrosine kinase inhibitor used for the treatment of lymphoblastic or chronic myeloid leukemia with resistance or intolerance to prior therapy.
DecitabineA chemotherapeutic pyrimidine nucleoside analogue used for the treatment of myelodysplastic syndromes (MDS) by inducing DNA hypomethylation and corresponding alterations in gene expression.
TelbivudineA thymidine nucleoside analog used for the treatment of chronic hepatitis B with clinical evidence of viral replication or persistent elevations in serum aminotransferases (ALT or AST).
PaliperidoneAn atypical antipsychotic used in the treatment of schizophrenia and other schizoaffective or delusional disorders.
AmobarbitalA barbiturate derivative used for the induction of sedation during procedures, short-term management of insomnia, and acute management of refractory tonic-clonic seizures.
AprobarbitalAprobarbital is a barbiturate derivative synthesized in the 1920s by Ernst Preiswerk. It was determined that the substance was capable of demonstrating sedative, hypnotic, and anticonvulsant effects. A primary treatment...
ButobarbitalFor the treatment of insomnia.
HeptabarbitalUsed mainly for sedation and hypnosis.
HexobarbitalFor the induction of anesthesia prior to the use of other general anesthetic agents and for induction of anesthesia for short surgical, diagnostic, or therapeutic procedures associated with minimal painful...
BarbitalA long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice...
5-fluorouridine5-fluorouridine is also known as FUrd, 5-Fluorouracil 1-beta-D-ribofuranoside, 5-Fur, or 5-Fluoro-uridine. 5-fluorouridine is a solid. This compound belongs to the pyrimidine nucleosides and analogues. These are compounds comprising a pyrimidine...
Thymidine monophosphate5-Thymidylic acid. A thymine nucleotide containing one phosphate group esterified to the deoxyribose moiety.
CytidineNot Available
Immucillin-GNot Available
Orotic acidNot Available
FormycinNot Available
UridineNot Available
UDP-alpha-D-glucuronic acidA nucleoside diphosphate sugar which serves as a source of glucuronic acid for polysaccharide biosynthesis. It may also be epimerized to UDP iduronic acid, which donates iduronic acid to polysaccharides....
ZebularineA chemically stable, cytidine analog that displays anti-tumor properties. It acts as a transition state analog inhibitor of cytidine deaminase by binding to the active site as covalent hydrates. Also...
Deoxycytidylyl-3',5'-guanosineNot Available
UracilNot Available
ThymineNot Available
Galactose-uridine-5'-diphosphateA nucleoside diphosphate sugar which can be epimerized into UDPglucose for entry into the mainstream of carbohydrate metabolism. Serves as a source of galactose in the synthesis of lipopolysaccharides, cerebrosides,...
EniluracilFor the treatment of cancer in combination with 5-fluorouracil.
5-IodouracilNot Available
6-aza uridine 5'-monophosphateNot Available
Deoxyuridine monophosphateNot Available
5,6-DiaminouracilNot Available
3-MethylcytosineNot Available
WillardiineWillardiine is a compound isolated from seeds of Acacia willariana.
Formycin BNot Available
SparsomycinAn antitumor antibiotic produced by Streptomyces sparsogenes. It inhibits protein synthesis in 70S and 80S ribosomal systems. [PubChem]
1-MethylcytosineNot Available
3-DeazacytidineNot Available
ThymidineThymidine is a pyrimidine deoxynucleoside. Thymidine is the DNA nucleoside T, which pairs with deoxyadenosine (A) in double-stranded DNA. In cell biology it is used to synchronize the cells in...
CyclouridineNot Available
MetoprineNot Available
Cyclic 3',5'-thymidine monophosphateNot Available
TroxacitabineInvestigated for use/treatment in leukemia (myeloid).
DenufosolFor use as an inhaled treatment for cystic fibrosis.
ThymectacinInvestigated for use/treatment in colorectal cancer.
OxypurinolIntended for the treatment of congestive heart failure and hyperuricemia.
ElacytarabineInvestigated for use/treatment in leukemia (unspecified) and melanoma.
ForodesineInvestigated for use/treatment in lymphoma (non-hodgkin's) and leukemia (lymphoid).
AlogliptinA dipeptidyl peptidase-4 (DPP-4) inhibitor used to treat hyperglycemia in patients with type 2 diabetes mellitus.
OcaperidoneInvestigated for use/treatment in schizophrenia and schizoaffective disorders.
ElvucitabineInvestigated for use/treatment in hepatitis (viral, B) and HIV infection.
DarapladibInvestigated for use/treatment in atherosclerosis.
SapacitabineInvestigated for use/treatment in solid tumors, cutaneous t-cell lymphoma, myelodysplastic syndrome, and leukemia (lymphoid).
TezacitabineInvestigated for use/treatment in colorectal cancer, lung cancer, leukemia (unspecified), and gastric cancer.
TAS-106Investigated for use/treatment in solid tumors and cancer/tumors (unspecified).
ClevudineInvestigated for use/treatment in hepatitis (viral, B).
RilpivirineA non-nucleoside reverse transcriptase inhibitor (NNRTI) used in combination with other antiretrovirals to specifically treat human immunodeficiency virus type 1 (HIV-1).
TrametinibA kinase inhibitor used to treat patients with specific types of melanoma, non-small cell lung cancer, and thyroid cancer.
SofosbuvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
TAS-102TAS-102 (Taiho Pharma USA, Inc.) is an anti-cancer drug under development and in stage 3 clinical trials for the treatment of colorectal cancer. It is composed of the thymidine phosphorylase...
HexetidineAn topical antiseptic agent used for disinfection and prevention of bacterial, fungal and yeast infections of the oral and vaginal mucosa.
FursultiamineCompound used for therapy of thiamine deficiency. It has also been suggested for several non-deficiency disorders but has not yet proven useful. Fursultiamine is a vitamin B1 derivative.
EpirizoleEpirizole is an oral nonsteroidal anti-inflammatory drug (NSAID) used for muscle and joint pain.
BarbexacloneCreated for the treatment for epilepsy, with the intent of creating an antiepileptic with less sedative properties than phenobarbital.
CarmofurCarmofur is a derivative of fluorouracil, and is an antineoplastic agent that has been used in the treatment of breast and colorectal cancer. Carmofur has been known to induce leukoencephalopathy.
Uridine triacetateA pyrimidine analog used for the reversal of overdose, regardless of the presence of symptoms, and early-onset, severe or life-threatening CNS toxicity or cardiotoxicity of fluorouracil or capecitabine.
DasabuvirA direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
TegafurAn antineoplastic agent used in combination with other anticancer medications to treat advanced gastric and colorectal cancers.
TrapidilUsed in the treatment of chronic stable angina .
PyrantelAn anthelmintic used to treat helminth infections.
2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine2'-cyano-2'-deoxy-1-(beta-D-arabinofuranosyl)cytosine has been used in trials studying the treatment of Advanced Colorectal Cancer.
AZD-4877AZD4877 has been used in trials studying the treatment of NHL, Tumors, Cancer, Lymphoma, and Neoplasms, among others.
DaprodustatDaprodustat has been used in trials studying the other, treatment, and basic science of Anaemia, Wound Healing, Tendon Injuries, Surgical Procedures, and Vascular Disease, Peripheral.
PF-06282999Pf 06282999 is under investigation in clinical trial NCT01626976 (A Study To Assess The Safety, Tolerability And Pharmacokinetics Of PF-06282999 Administered Orally In Healthy Adult Subjects).
BenfotiamineBenfotiamine has been investigated for the treatment and prevention of Diabetic Nephropathy and Diabetes Mellitus, Type 2.
MirodenafilMirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction.
RelugolixRelugolix has been used in trials studying the treatment of Endometriosis, Prostate Cancer, Uterine Fibroids, and Androgen Deprivation Treatment-naïve Nonmetastatic Prostate Cancer.
GisadenafilGisadenafil has been investigated for the treatment of Prostatic Hyperplasia.
GuadecitabineGuadecitabine is under investigation for the treatment of Previously Treated Metastatic Colorectal Cancer.
PF-04447943PF-04447943 has been investigated for the treatment of Alzheimer's Disease.
LetaxabanLetaxaban has been used in trials studying the treatment and prevention of Venous Thromboembolism and Acute Coronary Syndrome.
SorivudineSorivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.
BroxuridineBroxuridine has been used in trials studying the treatment of Leukemia, Stage I Prostate Cancer, Stage IIB Prostate Cancer, and Stage IIA Prostate Cancer.
MericitabineMericitabine has been investigated for the treatment of Hepatitis C, Chronic. Mericitabine is a polymerase inhibitor being developed for the treatment of chronic hepatitis C. Mericitabine is a prodrug of...
CensavudineCensavudine has been used in trials studying the treatment of HIV-1 Infection.
CE-224535CE-224535 has been used in trials studying the treatment of Osteoarthritis.
BrincidofovirBrincidofovir is under investigation for the prevention of Outcomes, Survival Rates, and Cytomegalovirus Disease. Brincidofovir has been investigated for the prevention and treatment of CMV, Adenovirus, BK Virus (BKV), Adenoviruses...
TAK-733TAK-733 has been used in trials studying the treatment of Advanced Metastatic Melanoma, Advanced Nonhematologic Malignancies, and Advanced Non-hematologic Malignancies.
Fozivudine TidoxilFozivudine Tidoxil has been used in trials studying the treatment of HIV Infections.
VerdiperstatVerdiperstat has been used in trials studying the basic science and treatment of Multiple System Atrophy (MSA).
DexelvucitabineDexelvucitabine has been used in trials studying the treatment of HIV Infections and Human Immunodeficiency Virus.
TetrahydrouridineTetrahydrouridine has been used in trials studying the treatment of Neoplasms, Lung Neoplasms, Breast Neoplasms, Sickle Cell Disease, and Head and Neck Cancer, among others.
Gemcitabine elaidateGemcitabine elaidate has been used in trials studying the treatment of Solid Tumor, Lung Cancer, Non-small-cell Lung Cancer, and Metastatic Pancreatic Adenocarcinoma.
NetivudineNetivudine has been used in trials studying the treatment of Chickenpox and HIV Infections.
RitanserinRitanserin has been used in trials studying the treatment of Cocaine-Related Disorders.
RacivirRacivir, also known as RCV, is an oxothiolane nucleoside reverse transcriptase inhibitor similar to emtricitabine and lamivudine. Racivir is a 50:50 mixture of emtricitabine DB00879 and its positive enantiomer. Racivir...
ZoliflodacinZoliflodacin has been used in trials studying the basic science and treatment of Gonorrhoea.
ApricitabineApricitabine has been used in trials studying the treatment of HIV Infections.
FiacitabineFiacitabine has been used in trials studying the treatment of HIV Infections and Cytomegalovirus Infections.
LY-2334737LY2334737 has been used in trials studying the treatment of Solid Tumor, Metastatic Tumor, and Malignant Solid Tumor.
MGL-3196MGL-3196 has been used in trials studying the treatment of Non-alcoholic steatohepatitis and Heterozygous Familial Hypercholesterolemia.
DoxifluridineDoxifluridine has been investigated for the treatment of Stomach Cancer.
5-fluoro-2'-deoxycytidine5-fluoro-2'-deoxycytidine has been used in trials studying the treatment of Neoplasms, Lung Neoplasms, Breast Neoplasms, Head and Neck Neoplasms, and Urinary Bladder Neoplasms, among others.
2'-fluoro-5-ethylarabinosyluracil2'-fluoro-5-ethylarabinosyluracil (FAU) has been used in trials studying the treatment of Small Intestine Lymphoma, Stage IV Mantle Cell Lymphoma, Waldenström Macroglobulinemia, Splenic Marginal Zone Lymphoma, and Recurrent Mantle Cell Lymphoma,...
TunicamycinTunicamycin is a mixture of homologous nucleoside antibiotics that inhibits the UDP-HexNAc: polyprenol-P HexNAc-1-P family of enzymes. One member of this family is the enzyme GlcNAc phosphotransferase (GPT), which catalyzes...
EnibomalNot Annotated
ProxibarbalProxibarbal is a derivative of barbiturates, which has been used to treat migraines. Proxibarbal was approved in France but was withdrawn from the market due to the risk of inducing...
RimazoliumRimazolium is an experimental analgesic drug .
FebarbamateNot Annotated
SulbutiamineSulbutiamine is a synthetic derivative of thiamine (vitamin B1) under the market name Arcalion that is composed of two modified thiamine molecules to form a dimer. It is highly lipophilic,...
EdoxudineA deoxythymidine analog used to treat herpetic keratitis.
AllobarbitalNot Annotated
MethylthiouracilNot Annotated
OxantelNot Annotated
CyclobarbitalNot Annotated
VinylbitalNot Annotated
Magnesium orotateMagnesium orotate is a magnesium salt of orotic acid and is poorly soluble in water. It is a source of magnesium and is used as a mineral supplement to treat...
BrodimoprimNot Annotated
BenzylthiouracilNot Annotated
ValopicitabineThe 3-O-valine ester prodrug of the nucleoside analog 2'-C-methylcytidine with anti-hepatitis C virus (HCV) activity. Upon administration, valopicitabine is converted into 2'-C-methylcytidine; upon phosphorylation into its 5-triphosphate form, this metabolite...
2'-C-methylcytidineA nucleoside analog with anti-hepatitis C virus (HCV) activity. Upon phosphorylation into its 5-triphosphate form, this metabolite inhibits viral RNA chain elongation and viral RNA-dependent RNA polymerase activity. This blocks...
Uridine diphosphate glucoseA key intermediate in carbohydrate metabolism. Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and...
CocarboxylaseThe coenzyme form of Vitamin B1 present in many animal tissues. It is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.
3'-UridinemonophosphateNot Available
2'-Deoxycytidine 5'-triphosphateNot Available
BrivudineBrivudine is used in the treatment of herpes zoster. Although not approved in the U.S. or Canada, it is approved in several European countries.
Cytidine-5'-MonophosphateA pyrimidine ribonucleoside 5'-monophosphate having cytosine as the nucleobase.
Uridine monophosphate5'-Uridylic acid. A uracil nucleotide containing one phosphate group esterified to the sugar moiety in the 2', 3' or 5' position.
Uridine 5'-triphosphateUridine 5'-(tetrahydrogen triphosphate). A uracil nucleotide containing three phosphate groups esterified to the sugar moiety.
EmivirineEmivirine has been used in trials studying the treatment of HIV Infections.
CiticolineCiticoline is a donor of choline in biosynthesis of choline-containing phosphoglycerides. It has been investigated for the treatment, supportive care, and diagnostic of Mania, Stroke, Hypomania, Cocaine Abuse, and Bipolar...
UlodesineUlodesine has been used in trials studying the treatment of Gout, Arthritis, Hyperuricemia, and Joint Disease.
FreselestatInvestigated for use/treatment in chronic obstructive pulmonary disease (COPD).
LumicitabineLumicitabine is under investigation in clinical trial NCT03010059 (A Study to Assess the Relative Bioavailability of JNJ64041575 Administered as 2 Different New Concept Formulations (Oral Suspension and Tablet) Compared to...
IQP-0528IQP-0528 is under investigation in clinical trial NCT03082690 (ImQuest (IQP) DuoGel Phase 1 Pharmacokinetic Study).
VibegronVibegron is under investigation in clinical trial NCT03806127 (Study to Evaluate the Efficacy and Safety of Vibegron Administered Orally for 12 Weeks to Women With Irritable Bowel Syndrome).
AZD-6482AZD-6482 is under investigation in clinical trial NCT00688714 (Study to Investigate Safety and Tolerability of a Single Dose of AZD6482).
NUC-1031NUC-1031 is under investigation in clinical trial NCT03610100 (Acelarin First Line Randomised Pancreatic Study).
TrelagliptinTrelagliptin is under investigation in clinical trial NCT03555591 (Specified Drug-Use Survey of Trelagliptin Tablets "Survey on Long-term Use in Patients With Type 2 Diabetes Mellitus").
FialuridineFialuridine is under investigation in clinical trial NCT01337466 (Biodistribution and Dosimetry Evaluation of [124I]FIAU).
BosentanA dual endothelin receptor antagonist used to treat pulmonary arterial hypertension.
TipiracilA thymidine phosphorylase inhibitor used as an adjunct treatment of adult patients with certain types of gastric or colorectal malignancies.
AdafosbuvirAdafosbuvir is under investigation in clinical trial NCT02894905 (A Study to Evaluate the Effect of Renal Impairment on the Pharmacokinetics of AL-335).
MavacamtenMavacamten is under investigation in clinical trial NCT03442764 (A Phase 2 Study of Mavacamten in Adults With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (nHCM)).
PRI-724PRI-724 is under investigation in clinical trial NCT03620474 (Safety and Effectiveness of PRI-724 for Hepatitis C or B Virus Derived Liver Cirrhosis).
ABT-072ABT-072 is under investigation in clinical trial NCT00890318 (A Study in Healthy Adult Subjects to Evaluate the Safety, Tolerability, and Pharmacokinetic Profiles of Multiple Doses of ABT-072 Used to Treat...
UprifosbuvirUprifosbuvir is under investigation in clinical trial NCT02332707 (Efficacy and Safety of Grazoprevir (MK-5172) and Uprifosbuvir (MK-3682) With Elbasvir (MK-8742) or Ruzasvir (MK-8408) for Chronic Hepatitis C Genotype (GT)1 and...
CambinolAn investigational histone deacetylase inhibitor that may have future use in cancer treatment.
5-methylcytidine 5'-monophosphateNot Available
Zidovudine monophosphateNot Available
Zidovudine diphosphateNot Available
TMPNot Available
BropirimineNot Available
5-BenzylacyclouridineNot Available
Stavudine triphosphateNot Available
DihydrouracilNot Available
Thymidine 5'-triphosphateNot Available
Orotidylic acidNot Available
5-AminouracilNot Available
N4-HydroxycytidineA cytidine analog being investigated to treat COVID-19.
Drugs & Drug Targets
DrugTargetType
ThiamineThiamin pyrophosphokinase 1target
ThiamineSolute carrier family 22 member 2transporter
ThiamineSolute carrier family 22 member 1transporter
ThiamineSolute carrier family 22 member 5transporter
ThiamineCytochrome P450 4B1enzyme
ThiamineThiamine transporter 1transporter
ThiamineThiamine transporter 2transporter
ThiamineThiamin pyrophosphokinase 1enzyme
ThiamineEctonucleoside triphosphate diphosphohydrolase 5enzyme
ThiamineThiamine-triphosphataseenzyme
ThiamineSerum albumincarrier
PyrimethamineBifunctional dihydrofolate reductase-thymidylate synthasetarget
PyrimethamineDihydrofolate reductasetarget
PyrimethamineCytochrome P450 2C8enzyme
PyrimethamineBeta-hexosaminidase subunit betatarget
PyrimethamineMultidrug and toxin extrusion protein 1transporter
PyrimethamineMultidrug and toxin extrusion protein 2transporter
ButabarbitalGlutamate receptor 2target
ButabarbitalGlutamate receptor ionotropic, kainate 2target
ButabarbitalGABA(A) Receptortarget
ButabarbitalSolute carrier family 2, facilitated glucose transporter member 1transporter
ButabarbitalNeuronal Acetylcholine (nACh) Receptor Subunitstarget
ButabarbitalGlutamate receptor 1target
ButabarbitalGlutamate receptor 3target
ButabarbitalGlutamate receptor 4target
ButabarbitalGlutamate receptor ionotropic, kainate 1target
ButabarbitalGlutamate receptor ionotropic, kainate 3target
ButabarbitalGlutamate receptor ionotropic, kainate 4target
ButabarbitalGlutamate receptor ionotropic, kainate 5target
ButabarbitalSerum albumincarrier
ButalbitalGamma-aminobutyric acid receptor subunit alpha-1target
ButalbitalGamma-aminobutyric acid receptor subunit alpha-2target
ButalbitalGamma-aminobutyric acid receptor subunit alpha-3target
ButalbitalGamma-aminobutyric acid receptor subunit alpha-4target
ButalbitalGamma-aminobutyric acid receptor subunit alpha-5target
ButalbitalGamma-aminobutyric acid receptor subunit alpha-6target
ButalbitalNeuronal acetylcholine receptor subunit alpha-4target
ButalbitalNeuronal acetylcholine receptor subunit alpha-7target
ButalbitalGlutamate receptor 2target
ButalbitalGlutamate receptor ionotropic, kainate 2target
ButalbitalGABA(A) Receptortarget
IdoxuridineThymidine kinasetarget
IdoxuridineDNAtarget
TalbutalGamma-aminobutyric acid receptor subunit alpha-1target
TalbutalGamma-aminobutyric acid receptor subunit alpha-2target
TalbutalGamma-aminobutyric acid receptor subunit alpha-3target
TalbutalGamma-aminobutyric acid receptor subunit alpha-4target
TalbutalGamma-aminobutyric acid receptor subunit alpha-5target
TalbutalGamma-aminobutyric acid receptor subunit alpha-6target
TalbutalNeuronal acetylcholine receptor subunit alpha-4target
TalbutalNeuronal acetylcholine receptor subunit alpha-7target
TalbutalGlutamate receptor 2target
TalbutalGlutamate receptor ionotropic, kainate 2target
TalbutalGABA(A) Receptortarget
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
PentobarbitalCytochrome P450 3A4enzyme
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
PentobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
PentobarbitalNeuronal acetylcholine receptor subunit alpha-4target
PentobarbitalNeuronal acetylcholine receptor subunit alpha-7target
PentobarbitalGlutamate receptor 2target
PentobarbitalGlutamate receptor ionotropic, kainate 2target
PentobarbitalCytochrome P450 2C19enzyme
PentobarbitalCytochrome P450 2A6enzyme
PentobarbitalGABA(A) Receptortarget
PentobarbitalNMDA receptortarget
PentobarbitalNuclear receptor subfamily 1 group I member 2target
FloxuridineThymidylate synthasetarget
FloxuridineThymidine phosphorylaseenzyme
FloxuridineCytochrome P450 2C9enzyme
FloxuridineThyroxine-binding globulincarrier
MinoxidilATP-sensitive inward rectifier potassium channel 1target
MinoxidilProstaglandin G/H synthase 1target
MinoxidilRenintarget
MinoxidilUDP-glucuronosyltransferase 1-1enzyme
CidofovirDNA polymerase catalytic subunittarget
CidofovirSolute carrier family 22 member 6transporter
CidofovirThymidine phosphorylaseenzyme
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
SecobarbitalCytochrome P450 2C8enzyme
SecobarbitalCytochrome P450 2C9enzyme
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
SecobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
SecobarbitalNeuronal acetylcholine receptor subunit alpha-4target
SecobarbitalNeuronal acetylcholine receptor subunit alpha-7target
SecobarbitalGlutamate receptor 2target
SecobarbitalGlutamate receptor ionotropic, kainate 2target
SecobarbitalCytochrome P450 1A2enzyme
SecobarbitalNMDA receptortarget
SecobarbitalCytochrome P450 2C19enzyme
TrifluridineThymidylate synthasetarget
TrifluridineDNAtarget
TrifluridineThymidine kinase, cytosolicenzyme
TrifluridineThymidine phosphorylaseenzyme
TrifluridineSolute carrier family 22 member 6transporter
TrifluridineSodium/nucleoside cotransporter 1transporter
TrifluridineEquilibrative nucleoside transporter 1transporter
TrifluridineEquilibrative nucleoside transporter 2transporter
TrifluridineSerum albumincarrier
TrimethoprimDihydrofolate reductasetarget
TrimethoprimCytochrome P450 2C8enzyme
TrimethoprimCytochrome P450 3A4enzyme
TrimethoprimP-glycoprotein 1transporter
TrimethoprimCytochrome P450 2C9enzyme
TrimethoprimCytochrome P450 1A2enzyme
TrimethoprimMultidrug and toxin extrusion protein 1transporter
TrimethoprimMultidrug and toxin extrusion protein 2transporter
GemcitabineRibonucleoside-diphosphate reductase large subunittarget
GemcitabineUMP-CMP kinasetarget
GemcitabineThymidylate synthasetarget
GemcitabineCytidine deaminaseenzyme
GemcitabineDeoxycytidine kinaseenzyme
GemcitabineP-glycoprotein 1transporter
GemcitabineMultidrug resistance-associated protein 7transporter
GemcitabineEquilibrative nucleoside transporter 1transporter
GemcitabineDNAtarget
GemcitabineSodium/nucleoside cotransporter 1transporter
GemcitabineEquilibrative nucleoside transporter 2transporter
GemcitabineSolute carrier family 28 member 3transporter
MetharbitalGamma-aminobutyric acid receptor subunit alpha-1target
MetharbitalGamma-aminobutyric acid receptor subunit alpha-2target
MetharbitalGamma-aminobutyric acid receptor subunit alpha-3target
MetharbitalGamma-aminobutyric acid receptor subunit alpha-4target
MetharbitalGamma-aminobutyric acid receptor subunit alpha-5target
MetharbitalGamma-aminobutyric acid receptor subunit alpha-6target
MetharbitalNeuronal acetylcholine receptor subunit alpha-4target
MetharbitalNeuronal acetylcholine receptor subunit alpha-7target
MetharbitalGlutamate receptor 2target
MetharbitalGlutamate receptor ionotropic, kainate 2target
MetharbitalGABA(A) Receptortarget
MethohexitalGamma-aminobutyric acid receptor subunit alpha-1target
MethohexitalCytochrome P450 2C19enzyme
ChlordiazepoxideGABA(A) Receptortarget
ChlordiazepoxideGABA(A) Receptor Benzodiazepine Binding Sitetarget
Buspirone5-hydroxytryptamine receptor 1Atarget
BuspironeDopamine D2 receptortarget
BuspironeCytochrome P450 3A4enzyme
BuspironeCytochrome P450 3A5enzyme
BuspironeCytochrome P450 3A7enzyme
BuspironeP-glycoprotein 1transporter
BuspironeCytochrome P450 2D6enzyme
BuspironeSerum albumincarrier
BuspironeAlpha-1-acid glycoprotein 1carrier
BuspironeDopamine D3 receptortarget
BuspironeDopamine D4 receptortarget
BuspironeAlpha-1 adrenergic receptorstarget
ZidovudineSerum albumincarrier
ZidovudineCytochrome P450 2A6enzyme
ZidovudineCytochrome P450 2C9enzyme
ZidovudineCytochrome P450 3A4enzyme
ZidovudineReverse transcriptase/RNaseHtarget
ZidovudineSolute carrier family 22 member 2transporter
ZidovudineSolute carrier family 22 member 6transporter
ZidovudineSolute carrier family 22 member 7transporter
ZidovudineSolute carrier family 22 member 8transporter
ZidovudineSolute carrier family 22 member 11transporter
ZidovudineSodium/nucleoside cotransporter 1transporter
ZidovudineEquilibrative nucleoside transporter 2transporter
ZidovudineP-glycoprotein 1transporter
ZidovudineMultidrug resistance-associated protein 4transporter
ZidovudineMultidrug resistance-associated protein 5transporter
ZidovudineATP-binding cassette sub-family G member 2transporter
ZidovudineTelomerase reverse transcriptasetarget
ZidovudineThymidine kinase, cytosolicenzyme
ZidovudineUDP-glucuronosyltransferase 2B7enzyme
ZidovudineUDP-glucuronosyltransferase 1-1enzyme
FluorouracilThymidylate synthasetarget
FluorouracilCytochrome P450 1A2enzyme
FluorouracilThymidine phosphorylaseenzyme
FluorouracilSerum albumincarrier
FluorouracilCytochrome P450 2C9enzyme
FluorouracilDihydropyrimidine dehydrogenase [NADP(+)]enzyme
FluorouracilUridine phosphorylase 1enzyme
FluorouracilUridine phosphorylase 2enzyme
FluorouracilDNAtarget
FluorouracilRNAtarget
FluorouracilCytochrome P450 2A6enzyme
FluorouracilCytochrome P450 2C8enzyme
FluorouracilMethylenetetrahydrofolate reductaseenzyme
FluorouracilThymidylate synthaseenzyme
FluorouracilUridine 5'-monophosphate synthaseenzyme
FluorouracilAmidophosphoribosyltransferaseenzyme
FluorouracilSolute carrier family 22 member 7transporter
FluorouracilEquilibrative nucleoside transporter 1transporter
FluorouracilATP-binding cassette sub-family G member 2transporter
FluorouracilCanalicular multispecific organic anion transporter 2transporter
FluorouracilMultidrug resistance-associated protein 4transporter
FluorouracilMultidrug resistance-associated protein 5transporter
FluorouracilThyroxine-binding globulincarrier
PropylthiouracilThyroid peroxidasetarget
PropylthiouracilMyeloperoxidaseenzyme
PropylthiouracilDopamine beta-hydroxylaseenzyme
PropylthiouracilCytochrome P450 1A1enzyme
PentostatinAdenosine deaminasetarget
ThiopentalGamma-aminobutyric acid receptor subunit alpha-1target
ThiopentalFatty-acid amide hydrolase 1target
ThiopentalGamma-aminobutyric acid receptor subunit alpha-2target
ThiopentalGamma-aminobutyric acid receptor subunit alpha-3target
ThiopentalGamma-aminobutyric acid receptor subunit alpha-4target
ThiopentalGamma-aminobutyric acid receptor subunit alpha-5target
ThiopentalGamma-aminobutyric acid receptor subunit alpha-6target
ThiopentalNeuronal acetylcholine receptor subunit alpha-4target
ThiopentalNeuronal acetylcholine receptor subunit alpha-7target
ThiopentalGlutamate receptor 2target
ThiopentalGlutamate receptor ionotropic, kainate 2target
ThiopentalCytochrome P450 3A Subfamilyenzyme
ThiopentalMuscarinic acetylcholine receptor M3target
ThiopentalCytochrome P450 2C19enzyme
ImatinibPlatelet-derived growth factor receptor betatarget
ImatinibTyrosine-protein kinase ABL1target
ImatinibMast/stem cell growth factor receptor Kittarget
ImatinibRET proto-oncogenetarget
ImatinibHigh affinity nerve growth factor receptortarget
ImatinibMacrophage colony-stimulating factor 1 receptortarget
ImatinibPlatelet-derived growth factor receptor alphatarget
ImatinibEpithelial discoidin domain-containing receptor 1target
ImatinibCytochrome P450 3A4enzyme
ImatinibBreakpoint cluster region proteintarget
ImatinibCytochrome P450 1A2enzyme
ImatinibCytochrome P450 2D6enzyme
ImatinibCytochrome P450 2C9enzyme
ImatinibCytochrome P450 2C19enzyme
ImatinibCytochrome P450 3A5enzyme
ImatinibCytochrome P450 3A7enzyme
ImatinibSolute carrier family 22 member 1transporter
ImatinibP-glycoprotein 1transporter
ImatinibSolute carrier family 22 member 2transporter
ImatinibATP-binding cassette sub-family G member 2transporter
ImatinibATP-binding cassette sub-family A member 3transporter
ImatinibProstaglandin G/H synthase 1enzyme
ImatinibSerum albumincarrier
ImatinibAlpha-1-acid glycoprotein 1carrier
ImatinibBile salt export pumptransporter
ImatinibCytochrome P450 2C8enzyme
StavudineSolute carrier family 22 member 6transporter
StavudineReverse transcriptase/RNaseHtarget
StavudineSodium/nucleoside cotransporter 1transporter
StavudineSerum albumincarrier
LamivudineDNAtarget
LamivudineProtein Ptarget
LamivudineMultidrug resistance-associated protein 1transporter
LamivudineSolute carrier family 22 member 6transporter
LamivudineATP-binding cassette sub-family G member 2transporter
LamivudineReverse transcriptase/RNaseHtarget
LamivudineSolute carrier family 22 member 1transporter
LamivudineSolute carrier family 22 member 2transporter
LamivudineSolute carrier family 22 member 3transporter
LamivudineDeoxycytidine kinaseenzyme
LamivudineUMP-CMP kinaseenzyme
LamivudinePhosphoglycerate kinase 1enzyme
LamivudineNucleoside diphosphate kinase Aenzyme
LamivudineNucleoside diphosphate kinase Benzyme
LamivudineCholine-phosphate cytidylyltransferase Aenzyme
LamivudineEthanolamine-phosphate cytidylyltransferaseenzyme
LamivudineP-glycoprotein 1transporter
LamivudineMultidrug resistance-associated protein 4transporter
LamivudineCanalicular multispecific organic anion transporter 2transporter
LamivudineCanalicular multispecific organic anion transporter 1transporter
Lamivudine5'(3')-deoxyribonucleotidase, cytosolic typeenzyme
LamivudineSerum albumincarrier
RisperidoneCytochrome P450 2D6enzyme
RisperidoneCytochrome P450 3A4enzyme
RisperidoneP-glycoprotein 1transporter
RisperidoneSerum albumincarrier
RisperidoneAlpha-1-acid glycoprotein 1carrier
Risperidone5-hydroxytryptamine receptor 2Atarget
RisperidoneDopamine D2 receptortarget
RisperidoneAlpha-1B adrenergic receptortarget
RisperidoneAlpha-2B adrenergic receptortarget
RisperidoneAlpha-1A adrenergic receptortarget
RisperidoneAlpha-2C adrenergic receptortarget
RisperidoneHistamine H1 receptortarget
Risperidone5-hydroxytryptamine receptor 2Ctarget
Risperidone5-hydroxytryptamine receptor 1Dtarget
Risperidone5-hydroxytryptamine receptor 1Atarget
Risperidone5-hydroxytryptamine receptor 7target
RisperidoneD(2L) dopamine receptortarget
RisperidoneDopamine D1 receptortarget
Uracil mustardDNAtarget
PrimidoneGamma-aminobutyric acid receptor subunit alpha-1target
PrimidoneCytochrome P450 2C19enzyme
PrimidoneCytochrome P450 2C9enzyme
PrimidoneCytochrome P450 3A4enzyme
PrimidoneGamma-aminobutyric acid receptor subunit alpha-2target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-3target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-4target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-5target
PrimidoneGamma-aminobutyric acid receptor subunit alpha-6target
PrimidoneNeuronal acetylcholine receptor subunit alpha-4target
PrimidoneNeuronal acetylcholine receptor subunit alpha-7target
PrimidoneGlutamate receptor 2target
PrimidoneGlutamate receptor ionotropic, kainate 2target
PrimidoneGABA(A) Receptortarget
PrimidoneTransient receptor potential cation channel subfamily M member 3transporter
PrimidoneCytochrome P450 2E1enzyme
PrimidoneCytochrome P450 1A2enzyme
PrimidoneUDP-glucuronosyltransferases (UGTs)enzyme
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
MethylphenobarbitalCytochrome P450 2C19enzyme
MethylphenobarbitalCytochrome P450 2B6enzyme
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
MethylphenobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
MethylphenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
MethylphenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
MethylphenobarbitalGlutamate receptor 2target
MethylphenobarbitalGlutamate receptor ionotropic, kainate 2target
MethylphenobarbitalNuclear receptor subfamily 1 group I member 2target
EmtricitabineReverse transcriptase/RNaseHtarget
EmtricitabineDeoxycytidine kinaseenzyme
EmtricitabineSerum albumincarrier
EmtricitabineMultidrug and toxin extrusion protein 1transporter
AzacitidineDNA (cytosine-5)-methyltransferase 1target
AzacitidineCytidine deaminaseenzyme
AzacitidineDNAtarget
AzacitidineRNAtarget
ZalcitabineDeoxycytidine kinaseenzyme
ZalcitabineSolute carrier family 22 member 6transporter
ZalcitabineSolute carrier family 22 member 7transporter
ZalcitabineReverse transcriptase/RNaseHtarget
ZalcitabineEquilibrative nucleoside transporter 1transporter
ZalcitabineEquilibrative nucleoside transporter 2transporter
ZalcitabineSerum albumincarrier
DipyridamolecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DipyridamolecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DipyridamolecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DipyridamoleAdenosine deaminasetarget
DipyridamoleMultidrug resistance-associated protein 4transporter
DipyridamoleMultidrug resistance-associated protein 5transporter
DipyridamoleP-glycoprotein 1transporter
DipyridamoleCalcipressin-1target
DipyridamoleAlpha-1-acid glycoprotein 1target
DipyridamoleSolute carrier organic anion transporter family member 1B1transporter
DipyridamoleSolute carrier organic anion transporter family member 1B3transporter
DipyridamoleSolute carrier organic anion transporter family member 2B1transporter
DipyridamoleBile salt export pumptransporter
CytarabineDNA polymerase betatarget
CytarabineCytidine deaminaseenzyme
CytarabineSolute carrier family 22 member 4transporter
CytarabineMultidrug resistance-associated protein 7transporter
CytarabineEquilibrative nucleoside transporter 1transporter
CytarabineDNAtarget
CytarabineCytochrome P450 3A4enzyme
CytarabineDeoxycytidine kinaseenzyme
Cytarabine5'-nucleotidaseenzyme
CytarabineDeoxycytidylate deaminaseenzyme
Rosuvastatin3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
RosuvastatinCytochrome P450 2C9enzyme
RosuvastatinMultidrug resistance-associated protein 4transporter
RosuvastatinSolute carrier organic anion transporter family member 1A2transporter
RosuvastatinSolute carrier organic anion transporter family member 1B3transporter
RosuvastatinSolute carrier organic anion transporter family member 2B1transporter
RosuvastatinCystine/glutamate transportertransporter
RosuvastatinSolute carrier organic anion transporter family member 1B1transporter
RosuvastatinBile salt export pumptransporter
RosuvastatinATP-binding cassette sub-family G member 2transporter
RosuvastatinSerum albumincarrier
RosuvastatinCanalicular multispecific organic anion transporter 1transporter
RosuvastatinSolute carrier family 22 member 8transporter
RosuvastatinSodium/bile acid cotransportertransporter
RosuvastatinIntegrin alpha-Ltarget
FlucytosineThymidylate synthasetarget
FlucytosineDNA (cytosine-5)-methyltransferase 1target
FlucytosineDNAtarget
CapecitabineThymidylate synthasetarget
CapecitabineThymidine phosphorylaseenzyme
CapecitabineCytidine deaminaseenzyme
CapecitabineLiver carboxylesterase 1enzyme
CapecitabineDihydropyrimidine dehydrogenase [NADP(+)]enzyme
CapecitabineCytochrome P450 2C9enzyme
CapecitabineDNAtarget
CapecitabineRNAtarget
ThiamylalGamma-aminobutyric acid receptor subunit alpha-1target
ThiamylalATP-sensitive inward rectifier potassium channel 8target
ThiamylalATP-sensitive inward rectifier potassium channel 11target
ThiamylalCytochrome P450 2C9enzyme
ThiamylalCytochrome P450 3A4enzyme
ThiamylalCytochrome P450 2E1enzyme
PhenobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
PhenobarbitalCytochrome P450 2C19enzyme
PhenobarbitalCytochrome P450 2C9enzyme
PhenobarbitalCytochrome P450 2B6enzyme
PhenobarbitalCytochrome P450 2C8enzyme
PhenobarbitalCytochrome P450 1A2enzyme
PhenobarbitalCytochrome P450 3A4enzyme
PhenobarbitalCanalicular multispecific organic anion transporter 2transporter
PhenobarbitalBile salt export pumptransporter
PhenobarbitalP-glycoprotein 1transporter
PhenobarbitalMultidrug resistance-associated protein 1transporter
PhenobarbitalSolute carrier organic anion transporter family member 2A1transporter
PhenobarbitalCanalicular multispecific organic anion transporter 1transporter
PhenobarbitalNeuronal acetylcholine receptor subunit alpha-4target
PhenobarbitalNeuronal acetylcholine receptor subunit alpha-7target
PhenobarbitalGlutamate receptor 2target
PhenobarbitalGlutamate receptor ionotropic, kainate 2target
PhenobarbitalCytochrome P450 2A6enzyme
PhenobarbitalCytochrome P450 2E1enzyme
PhenobarbitalCytochrome P450 3A5enzyme
PhenobarbitalCytochrome P450 1A1enzyme
PhenobarbitalCytochrome P450 2C18enzyme
PhenobarbitalCytochrome P450 3A7enzyme
PhenobarbitalCytochrome P450 4B1enzyme
PhenobarbitalNMDA receptortarget
PhenobarbitalNuclear receptor subfamily 1 group I member 2target
PhenobarbitalUDP-glucuronosyltransferase 1-1enzyme
PhenobarbitalUDP-glucuronosyltransferase 2B7enzyme
DasatinibTyrosine-protein kinase ABL1target
DasatinibAbelson tyrosine-protein kinase 2target
DasatinibProto-oncogene tyrosine-protein kinase Srctarget
DasatinibTyrosine-protein kinase Fyntarget
DasatinibTyrosine-protein kinase Lcktarget
DasatinibTyrosine-protein kinase Yestarget
DasatinibMast/stem cell growth factor receptor Kittarget
DasatinibPlatelet-derived growth factor receptor betatarget
DasatinibEphrin type-A receptor 2target
DasatinibSignal transducer and activator of transcription 5Btarget
DasatinibCytochrome P450 3A4enzyme
DasatinibP-glycoprotein 1transporter
DasatinibATP-binding cassette sub-family G member 2transporter
DasatinibCytochrome P450 1A1enzyme
DasatinibCytochrome P450 1A2enzyme
DasatinibCytochrome P450 1B1enzyme
DasatinibCytochrome P450 3A5enzyme
DasatinibDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DasatinibTyrosine-protein kinase BTKtarget
DasatinibNuclear receptor subfamily 4 group A member 3target
DasatinibBreakpoint cluster region proteintarget
DasatinibTyrosine-protein kinase CSKtarget
DasatinibEphrin type-A receptor 5target
DasatinibEphrin type-B receptor 4target
DasatinibTyrosine-protein kinase Fgrtarget
DasatinibTyrosine-protein kinase FRKtarget
DasatinibHeat shock cognate 71 kDa proteintarget
DasatinibTyrosine-protein kinase Lyntarget
DasatinibMitogen-activated protein kinase kinase kinase MLTtarget
DasatinibMitogen-activated protein kinase 14target
DasatinibAmidophosphoribosyltransferasetarget
DecitabineDNAtarget
DecitabineDNA (cytosine-5)-methyltransferase 1target
DecitabineDeoxycytidine kinaseenzyme
DecitabineUMP-CMP kinaseenzyme
DecitabineNucleoside diphosphokinaseenzyme
DecitabineCytidine deaminaseenzyme
DecitabineDNA (cytosine-5)-methyltransferase 3Atarget
DecitabineDNA (cytosine-5)-methyltransferase 3Btarget
DecitabineSodium/nucleoside cotransporter 1transporter
TelbivudineProtein Ptarget
TelbivudineDNAtarget
PaliperidoneDopamine D2 receptortarget
Paliperidone5-hydroxytryptamine receptor 2Atarget
PaliperidoneHistamine H1 receptortarget
PaliperidoneAlpha-1A adrenergic receptortarget
PaliperidoneAlpha-1B adrenergic receptortarget
PaliperidoneDopamine D3 receptortarget
PaliperidoneDopamine D4 receptortarget
PaliperidoneDopamine D1 receptortarget
PaliperidoneAlpha-2A adrenergic receptortarget
PaliperidoneAlpha-2B adrenergic receptortarget
PaliperidoneAlpha-2C adrenergic receptortarget
Paliperidone5-hydroxytryptamine receptor 1Atarget
Paliperidone5-hydroxytryptamine receptor 1Dtarget
Paliperidone5-hydroxytryptamine receptor 2Ctarget
Paliperidone5-hydroxytryptamine receptor 7target
PaliperidoneCytochrome P450 3A4enzyme
PaliperidoneCytochrome P450 2D6enzyme
PaliperidoneCytochrome P450 3A5enzyme
PaliperidoneP-glycoprotein 1transporter
AmobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
AmobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
AmobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
AmobarbitalNeuronal acetylcholine receptor subunit alpha-4target
AmobarbitalNeuronal acetylcholine receptor subunit alpha-7target
AmobarbitalGlutamate receptor 2target
AmobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
AmobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
AmobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
AmobarbitalGlutamate receptor ionotropic, kainate 2target
AprobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
AprobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
AprobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
AprobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
AprobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
AprobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
AprobarbitalNeuronal acetylcholine receptor subunit alpha-4target
AprobarbitalNeuronal acetylcholine receptor subunit alpha-7target
AprobarbitalGlutamate receptor 2target
AprobarbitalGlutamate receptor ionotropic, kainate 2target
AprobarbitalCytochrome P450 3A4enzyme
ButobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
ButobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
ButobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
ButobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
ButobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
ButobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
ButobarbitalNeuronal acetylcholine receptor subunit alpha-4target
ButobarbitalNeuronal acetylcholine receptor subunit alpha-7target
ButobarbitalGlutamate receptor 2target
ButobarbitalGlutamate receptor ionotropic, kainate 2target
HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-1target
HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-2target
HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-3target
HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-4target
HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-5target
HeptabarbitalGamma-aminobutyric acid receptor subunit alpha-6target
HeptabarbitalNeuronal acetylcholine receptor subunit alpha-4target
HeptabarbitalNeuronal acetylcholine receptor subunit alpha-7target
HeptabarbitalGlutamate receptor 2target
HeptabarbitalGlutamate receptor ionotropic, kainate 2target
HexobarbitalGamma-aminobutyric acid receptor subunit alpha-1target
HexobarbitalCytochrome P450 2C9enzyme
HexobarbitalCytochrome P450 2C19enzyme
HexobarbitalProstaglandin G/H synthase 1enzyme
HexobarbitalGamma-aminobutyric acid receptor subunit alpha-2target
HexobarbitalGamma-aminobutyric acid receptor subunit alpha-3target
HexobarbitalGamma-aminobutyric acid receptor subunit alpha-4target
HexobarbitalGamma-aminobutyric acid receptor subunit alpha-5target
HexobarbitalGamma-aminobutyric acid receptor subunit alpha-6target
HexobarbitalNeuronal acetylcholine receptor subunit alpha-4target
HexobarbitalNeuronal acetylcholine receptor subunit alpha-7target
HexobarbitalGlutamate receptor 2target
HexobarbitalGlutamate receptor ionotropic, kainate 2target
BarbitalGamma-aminobutyric acid receptor subunit alpha-1target
BarbitalGamma-aminobutyric acid receptor subunit alpha-2target
BarbitalGamma-aminobutyric acid receptor subunit alpha-3target
BarbitalGamma-aminobutyric acid receptor subunit alpha-4target
BarbitalGamma-aminobutyric acid receptor subunit alpha-5target
BarbitalGamma-aminobutyric acid receptor subunit alpha-6target
BarbitalNeuronal acetylcholine receptor subunit alpha-4target
BarbitalNeuronal acetylcholine receptor subunit alpha-7target
BarbitalGlutamate receptor 2target
BarbitalGlutamate receptor ionotropic, kainate 2target
BarbitalCytochrome P450 3A4enzyme
BarbitalCytochrome P450 2C19enzyme
5-fluorouridineUridine phosphorylasetarget
5-fluorouridineSuperoxide dismutase [Cu-Zn]target
5-fluorouridineThyroxine-binding globulincarrier
Thymidine monophosphateThymidylate kinasetarget
Thymidine monophosphateThymidylate kinasetarget
Thymidine monophosphateThymidine kinasetarget
Thymidine monophosphateThymidylate synthasetarget
Thymidine monophosphateDNA topoisomerase 1target
Thymidine monophosphateThymidylate synthasetarget
Thymidine monophosphatePCZA361.16target
Thymidine monophosphateDNA polymerase III subunit epsilontarget
Thymidine monophosphateGlucose-1-phosphate thymidylyltransferasetarget
CytidineUridine-cytidine kinase 2target
Immucillin-GPurine nucleoside phosphorylasetarget
Orotic acidOrotate phosphoribosyltransferasetarget
Orotic acidDihydroorotate dehydrogenase (quinone), mitochondrialtarget
Orotic acidDihydroorotate dehydrogenase (quinone)target
Orotic acidDihydroorotasetarget
Orotic acidDihydroorotate dehydrogenase A (fumarate)target
FormycinS-methyl-5'-thioadenosine phosphorylasetarget
Formycin5'-methylthioadenosine/S-adenosylhomocysteine nucleosidasetarget
UridineU6 snRNA-associated Sm-like protein LSm6target
UridineNucleoside-specific channel-forming protein tsxtarget
UridineEquilibrative nucleoside transporter 1transporter
UDP-alpha-D-glucuronic acidGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3target
UDP-alpha-D-glucuronic acidUDP-glucose 6-dehydrogenasetarget
UDP-alpha-D-glucuronic acidUDP-glucose 4-epimerasetarget
ZebularineCytidine deaminasetarget
Deoxycytidylyl-3',5'-guanosineRibonuclease pancreatictarget
UracilDihydropyrimidine dehydrogenase [NADP(+)]target
UracilUridine-cytidine kinase-like 1target
UracilUracil-DNA glycosylasetarget
UracilUracil-DNA glycosylasetarget
UracilRibosomal small subunit pseudouridine synthase Atarget
UracilUracil-DNA glycosylasetarget
UracilPyrimidine-nucleoside phosphorylasetarget
ThymineDeoxyribodipyrimidine photo-lyasetarget
ThymineThymidine phosphorylasetarget
Galactose-uridine-5'-diphosphateHisto-blood group ABO system transferasetarget
Galactose-uridine-5'-diphosphateUDP-glucose 4-epimerasetarget
Galactose-uridine-5'-diphosphateBeta-1,4-galactosyltransferase 1target
EniluracilDihydropyrimidine dehydrogenase [NADP(+)]target
EniluracilAldehyde oxidasetarget
EniluracilXanthine dehydrogenase/oxidasetarget
5-IodouracilDihydropyrimidine dehydrogenase [NADP(+)]target
Deoxyuridine monophosphateDeoxyuridine 5'-triphosphate nucleotidohydrolasetarget
Deoxyuridine monophosphateThymidylate synthasetarget
Deoxyuridine monophosphateThymidylate synthasetarget
Deoxyuridine monophosphateThymidylate synthasetarget
Deoxyuridine monophosphateThymidylate synthase ThyXtarget
Deoxyuridine monophosphatePol polyproteintarget
Deoxyuridine monophosphateDeoxyuridine 5'-triphosphate nucleotidohydrolasetarget
Deoxyuridine monophosphateThymidylate synthasetarget
3-MethylcytosineCap-specific mRNA (nucleoside-2'-O-)-methyltransferasetarget
WillardiineGlutamate receptor 2target
Formycin BPurine nucleoside phosphorylase DeoD-typetarget
Formycin BHypoxanthine-guanine phosphoribosyltransferasetarget
1-MethylcytosineCap-specific mRNA (nucleoside-2'-O-)-methyltransferasetarget
3-DeazacytidineCytidine deaminasetarget
ThymidineThymidylate kinasetarget
ThymidineThymidine kinasetarget
ThymidineUridine phosphorylasetarget
ThymidineThymidine kinasetarget
ThymidineThymidine kinase 2, mitochondrialtarget
ThymidineNucleoside-specific channel-forming protein tsxtarget
ThymidineGlucose-1-phosphate thymidylyltransferasetarget
ThymidineSolute carrier family 28 member 3transporter
CyclouridineUridine phosphorylasetarget
MetoprineHistamine N-methyltransferasetarget
Cyclic 3',5'-thymidine monophosphate5'(3')-deoxyribonucleotidase, mitochondrialtarget
TroxacitabineDNAtarget
TroxacitabineDeoxycytidine kinaseenzyme
DenufosolP2Y purinoceptor 2target
ThymectacinThymidylate synthasetarget
OxypurinolXanthine dehydrogenase/oxidasetarget
ElacytarabineDeoxycytidine kinasetarget
ForodesinePurine nucleoside phosphorylasetarget
AlogliptinDipeptidyl peptidase 4target
AlogliptinCytochrome P450 3A4enzyme
AlogliptinCytochrome P450 2D6enzyme
OcaperidoneDopamine D2 receptortarget
OcaperidoneHistamine H1 receptortarget
OcaperidoneAlpha-1A adrenergic receptortarget
OcaperidoneAlpha-1B adrenergic receptortarget
OcaperidoneAlpha-2A adrenergic receptortarget
OcaperidoneAlpha-1D adrenergic receptortarget
OcaperidoneAlpha-2B adrenergic receptortarget
OcaperidoneAlpha-2C adrenergic receptortarget
Ocaperidone5-hydroxytryptamine receptor 2Atarget
Ocaperidone5-hydroxytryptamine receptor 2Btarget
Ocaperidone5-hydroxytryptamine receptor 2Ctarget
DarapladibCytosolic phospholipase A2target
TezacitabineRibonucleoside-diphosphate reductase large subunittarget
TezacitabineThymidine phosphorylaseenzyme
RilpivirineCytochrome P450 3A4enzyme
RilpivirineReverse transcriptase/RNaseHtarget
RilpivirineNuclear receptor subfamily 1 group I member 2target
RilpivirineCytochrome P450 2C19enzyme
RilpivirineCytochrome P450 2B6enzyme
RilpivirineP-glycoprotein 1transporter
RilpivirineATP-binding cassette sub-family G member 2transporter
RilpivirineSolute carrier organic anion transporter family member 1B1transporter
RilpivirineSolute carrier organic anion transporter family member 1B3transporter
RilpivirineSerum albumincarrier
RilpivirineCytochrome P450 2D6enzyme
TrametinibCytochrome P450 2C8enzyme
TrametinibCytochrome P450 3A4enzyme
TrametinibDual specificity mitogen-activated protein kinase kinase 1target
TrametinibDual specificity mitogen-activated protein kinase kinase 2target
SofosbuvirP-glycoprotein 1transporter
SofosbuvirATP-binding cassette sub-family G member 2transporter
SofosbuvirRNA-dependent RNA-polymerasetarget
SofosbuvirLysosomal protective proteinenzyme
SofosbuvirCarboxylesteraseenzyme
SofosbuvirHistidine triad nucleotide-binding protein 1enzyme
SofosbuvirUMP-CMP kinaseenzyme
SofosbuvirNucleoside diphosphate kinase Aenzyme
DasabuvirNonstructural protein 5B (NS5B)target
DasabuvirCytochrome P450 2C8enzyme
DasabuvirCytochrome P450 3A4enzyme
DasabuvirCytochrome P450 2D6enzyme
DasabuvirUDP-glucuronosyltransferase 1-4enzyme
DasabuvirATP-binding cassette sub-family G member 2transporter
DasabuvirATP-binding cassette sub-family B member 5transporter
DasabuvirP-glycoprotein 1transporter
TegafurCytochrome P450 2A6enzyme
TegafurThymidylate synthasetarget
TegafurCytochrome P450 1A2enzyme
TegafurCytochrome P450 2C8enzyme
TegafurCytochrome P450 2E1enzyme
TegafurCytochrome P450 3A5enzyme
TegafurThyroxine-binding globulincarrier
TrapidilPlatelet-derived growth factor receptor betatarget
TrapidilCyclic nucleotide phosphodiesterasetarget
PyrantelG-protein coupled receptor 35target
PyrantelCytochrome P450 4A11enzyme
PyrantelMuscarinic acetylcholine receptor M1target
MirodenafilCytochrome P450 3A Subfamilyenzyme
Ritanserin5-hydroxytryptamine receptor 2Atarget
RitanserinCytochrome P450 2D6enzyme
ApricitabineReverse transcriptase/RNaseHtarget
EdoxudineSerum albumincarrier
EdoxudineDNA polymerasetarget
Uridine diphosphate glucoseGalactose-1-phosphate uridylyltransferasetarget
Uridine diphosphate glucoseUDP-glucose 4-epimerasetarget
Uridine diphosphate glucoseAlpha,alpha-trehalose-phosphate synthase [UDP-forming]target
Uridine diphosphate glucoseGlucose-1-phosphate thymidylyltransferasetarget
Uridine diphosphate glucoseUDP-glucose 4-epimerasetarget
Uridine diphosphate glucoseDNA beta-glucosyltransferasetarget
Uridine diphosphate glucoseGlycosyltransferase 6 domain-containing protein 1target
Uridine diphosphate glucoseWbpPtarget
Uridine diphosphate glucoseGlycogenin-1target
CocarboxylaseAcetolactate synthase, catabolictarget
CocarboxylasePyruvate dehydrogenase E1 componenttarget
CocarboxylasePyruvate-flavodoxin oxidoreductasetarget
CocarboxylaseIndole-3-pyruvate decarboxylasetarget
CocarboxylaseCarboxyethylarginine synthasetarget
CocarboxylaseTransketolase 1target
CocarboxylaseRNAtarget
CocarboxylaseBenzoylformate decarboxylaseenzyme
CocarboxylasePyruvate oxidaseenzyme
3'-UridinemonophosphateRibonuclease pancreatictarget
2'-Deoxycytidine 5'-triphosphateAnaerobic ribonucleoside-triphosphate reductasetarget
2'-Deoxycytidine 5'-triphosphateDeoxycytidine triphosphate deaminasetarget
2'-Deoxycytidine 5'-triphosphateDNA polymerase I, thermostabletarget
2'-Deoxycytidine 5'-triphosphateRibonucleoside-diphosphate reductase 2 subunit alphatarget
BrivudineThymidine kinase 2, mitochondrialtarget
BrivudineDNA polymerasetarget
BrivudineThymidine kinasetarget
Cytidine-5'-MonophosphateUridine-cytidine kinase 2target
Cytidine-5'-Monophosphate3-deoxy-manno-octulosonate cytidylyltransferasetarget
Cytidine-5'-Monophosphate2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthasetarget
Cytidine-5'-MonophosphateBifunctional enzyme IspD/IspFtarget
Cytidine-5'-MonophosphateUMP-CMP kinasetarget
Cytidine-5'-Monophosphate2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthasetarget
Cytidine-5'-MonophosphateCytidylate kinasetarget
Cytidine-5'-MonophosphateCoenzyme A biosynthesis bifunctional protein CoaBCtarget
Cytidine-5'-MonophosphateAlpha-2,3-/2,8-sialyltransferasetarget
Uridine monophosphateUridine-cytidine kinase-like 1target
Uridine monophosphateGalactose-1-phosphate uridylyltransferasetarget
Uridine monophosphateThymidylate synthasetarget
Uridine monophosphateGlycosyltransferase 6 domain-containing protein 1target
Uridine monophosphateU6 snRNA-associated Sm-like protein LSm6target
Uridine monophosphateUracil phosphoribosyltransferasetarget
Uridine monophosphateBeta-1,4-galactosyltransferase 1target
Uridine monophosphateInterferon-stimulated gene 20 kDa proteintarget
Uridine monophosphateOrotidine 5'-phosphate decarboxylasetarget
Uridine monophosphateBifunctional protein PyrRtarget
Uridine monophosphateUracil phosphoribosyltransferasetarget
Uridine monophosphateBifunctional polymyxin resistance protein ArnAtarget
Uridine monophosphateRibosomal small subunit pseudouridine synthase Atarget
Uridine 5'-triphosphateUridine-cytidine kinase 2target
Uridine 5'-triphosphateGenome polyproteintarget
Uridine 5'-triphosphateGenome polyproteintarget
EmivirineGag-Pol polyproteintarget
CiticolineLicC proteintarget
FreselestatChymotrypsin-like elastase family member 1target
FreselestatNeutrophil elastasetarget
BosentanEndothelin B receptortarget
BosentanEndothelin-1 receptortarget
BosentanCytochrome P450 3A4enzyme
BosentanCytochrome P450 2C9enzyme
BosentanBile salt export pumptransporter
TipiracilThymidine phosphorylasetarget
TipiracilSolute carrier family 22 member 2carrier
TipiracilMultidrug and toxin extrusion protein 1carrier
TipiracilSolute carrier family 22 member 2transporter
TipiracilMultidrug and toxin extrusion protein 1transporter
CambinolNAD-dependent protein deacetylase sirtuin-1target
CambinolNAD-dependent protein deacetylase sirtuin-2target
CambinolNAD-dependent protein deacylase sirtuin-5, mitochondrialtarget
Zidovudine monophosphateThymidylate kinasetarget
Zidovudine monophosphateThymidylate kinasetarget
Zidovudine diphosphateNucleoside diphosphate kinase Atarget
TMPSingle-stranded DNA-binding proteintarget
BropirimineDihydroneopterin aldolasetarget
5-BenzylacyclouridineUridine phosphorylasetarget
5-BenzylacyclouridineUridine phosphorylase 1target
Stavudine triphosphateNucleoside diphosphate kinase Atarget
Thymidine 5'-triphosphateThymidine kinase, cytosolictarget
Thymidine 5'-triphosphateAnaerobic ribonucleoside-triphosphate reductasetarget
Thymidine 5'-triphosphateThymidylate kinasetarget
Thymidine 5'-triphosphateGlucose-1-phosphate thymidylyltransferase 2target
Thymidine 5'-triphosphateDNA primase/helicasetarget
Thymidine 5'-triphosphateGlucose-1-phosphate thymidylyltransferasetarget
Thymidine 5'-triphosphateThymidine kinase 2, mitochondrialtarget
Thymidine 5'-triphosphateThymidine kinasetarget
Thymidine 5'-triphosphateRibonucleoside-diphosphate reductase 2 subunit alphatarget
Thymidine 5'-triphosphateGlucose-1-phosphate thymidylyltransferasetarget
5-AminouracilRibonuclease pancreatictarget