Tocopherols

Name
Tocopherols
Accession Number
DBCAT000372
Description

A collective name for a group of closely related lipids that contain substitutions on the 2H-1-benzopyran-6-ol nucleus and a long hydrocarbon chain of isoprenoid units. They are antioxidants by virtue of the phenolic hydrogen. Tocopherols react with the most reactive form of oxygen and protect unsaturated fatty acids from oxidation.

Drugs
DrugDrug Description
alpha-Tocopherol succinateA form of vitamin E used to treat and prevent vitamin deficiencies.
D-alpha-Tocopherol acetateA form of vitamin E used to treat and prevent vitamin deficiencies.
alpha-Tocopherol acetateA form of vitamin E used to treat and prevent vitamin deficiencies.
gamma-Tocopherolgamma-Tocopherol is under investigation in clinical trial NCT00836368 (In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics).
Drugs & Drug Targets
DrugTargetType
alpha-Tocopherol succinateSEC14-like protein 3target
alpha-Tocopherol succinateSEC14-like protein 2target
alpha-Tocopherol succinateNuclear receptor subfamily 1 group I member 2target
alpha-Tocopherol succinateProtein kinase C beta typetarget
alpha-Tocopherol succinateArachidonate 5-lipoxygenasetarget
alpha-Tocopherol succinateProtein kinase C alpha typetarget
alpha-Tocopherol succinateAlpha-tocopherol transfer proteincarrier
alpha-Tocopherol succinateGlutathione S-transferase A2enzyme
alpha-Tocopherol succinateGlutathione S-transferase Penzyme
alpha-Tocopherol succinateGlutathione S-transferase omega-1enzyme
alpha-Tocopherol succinateGlutathione S-transferase Mu 3enzyme
alpha-Tocopherol succinateGlutamate--cysteine ligase catalytic subunitenzyme
alpha-Tocopherol succinateNAD(P)H dehydrogenase [quinone] 1enzyme
alpha-Tocopherol succinateHeme oxygenase 1enzyme
alpha-Tocopherol succinateSuperoxide dismutase [Cu-Zn]enzyme
alpha-Tocopherol succinateLung epithelial cellstarget
alpha-Tocopherol succinateDiacylglycerol kinasetarget
D-alpha-Tocopherol acetateSEC14-like protein 3target
D-alpha-Tocopherol acetateSEC14-like protein 2target
D-alpha-Tocopherol acetateNuclear receptor subfamily 1 group I member 2target
D-alpha-Tocopherol acetateProtein kinase C beta typetarget
D-alpha-Tocopherol acetateArachidonate 5-lipoxygenasetarget
D-alpha-Tocopherol acetateProtein kinase C alpha typetarget
D-alpha-Tocopherol acetateAlpha-tocopherol transfer proteincarrier
D-alpha-Tocopherol acetateGlutathione S-transferase A2enzyme
D-alpha-Tocopherol acetateGlutathione S-transferase Penzyme
D-alpha-Tocopherol acetateGlutathione S-transferase omega-1enzyme
D-alpha-Tocopherol acetateGlutathione S-transferase Mu 3enzyme
D-alpha-Tocopherol acetateGlutamate--cysteine ligase catalytic subunitenzyme
D-alpha-Tocopherol acetateNAD(P)H dehydrogenase [quinone] 1enzyme
D-alpha-Tocopherol acetateHeme oxygenase 1enzyme
D-alpha-Tocopherol acetateSuperoxide dismutase [Cu-Zn]enzyme
alpha-Tocopherol acetateLeukotriene-B(4) omega-hydroxylase 1enzyme
alpha-Tocopherol acetateCytochrome P450 3A4enzyme
alpha-Tocopherol acetateFree radicalstarget
alpha-Tocopherol acetateAlpha-tocopherol transfer proteintransporter
alpha-Tocopherol acetateSEC14-like protein 4transporter
alpha-Tocopherol acetateSEC14-like protein 2transporter
alpha-Tocopherol acetateSEC14-like protein 3transporter
alpha-Tocopherol acetateApolipoprotein B receptortransporter
alpha-Tocopherol acetateScavenger receptor class B member 1transporter
alpha-Tocopherol acetateP-glycoprotein 1transporter
alpha-Tocopherol acetateVery low-density lipoprotein receptorcarrier
alpha-Tocopherol acetateLow-density lipoprotein receptorcarrier