Food Additives

Substances which are of little or no nutritive value, but are used in the processing or storage of foods or animal feed, especially in the developed countries; includes ANTIOXIDANTS; FOOD PRESERVATIVES; FOOD COLORING AGENTS; FLAVORING AGENTS; ANTI-INFECTIVE AGENTS (both plain and LOCAL); VEHICLES; EXCIPIENTS and other similarly used substances. Many of the same substances are PHARMACEUTIC AIDS when added to pharmaceuticals rather than to foods.
DrugDrug NameDrug Indication
DB00168AspartameUsed as a diet supplement and sugar substitute.
DB00742MannitolUsed for the promotion of diuresis before irreversible renal failure becomes established, the reduction of intracranial pressure, the treatment of cerebral edema, and the promotion of urinary excretion of toxic substances.
DB00974Edetic AcidFor the reduction of blood levels and depot stores of lead in lead poisoning (acute and chronic) and lead encephalopathy, in both pediatric populations and adults.
DB01638SorbitolUsed as a non-stimulant laxative via an oral suspension or enema.
DB02772SucroseNot Available
DB03323MaltoseNot Available
DB03793Benzoic AcidNot Available
DB04173FructoseNot Available
DB04465LactoseNot Available
DB09112Sodium NitriteFor sequential use with sodium thiosulfate for the treatment of acute cyanide poisoning that is judged to be life-threatening [FDA Label].
DB09341GlucoseGlucose pharmaceutical formulations (oral tablets, injections) are indicated for caloric supply and carbohydrate supplementation in case of nutrient deprivation. It is also used in metabolic disorders such as hypoglycemia.
DB09344Invert sugarNot Available
DB11093Calcium CitrateFor use as an over the counter calcium supplement.
DB11195XylitolNot Available
DB11253Xanthan gumNot Available
DB12418SaccharinNot Available
DB12942LactitolNot Available
DrugDrug NameTargetType
DB00168AspartameTaste receptor type 1 member 2target
DB00168AspartameTransient receptor potential cation channel subfamily V member 1target
DB00168AspartameSolute carrier family 22 member 6transporter
DB00168AspartameSolute carrier family 22 member 8transporter
DB00168AspartameSolute carrier family 22 member 11transporter
DB00168AspartameTaste receptor type 1 member 3target
DB00742MannitolMultidrug resistance protein 1transporter
DB00742MannitolMannitol dehydrogenaseenzyme
DB00974Edetic AcidLeadtarget
DB00974Edetic AcidIrontarget
DB00974Edetic AcidManganese cationtarget
DB00974Edetic AcidAdenosine deaminaseenzyme
DB00974Edetic AcidCytochrome P450 1A2enzyme
DB00974Edetic AcidSerum paraoxonase/lactonase 3enzyme
DB00974Edetic AcidCytochrome P450 19A1enzyme
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolMalate synthase Gtarget
DB02772SucroseBeta-lactamasetarget
DB02772SucroseNitric oxide synthase oxygenasetarget
DB02772SucroseLysozyme Ctarget
DB02772SucroseSeptum formation protein Maftarget
DB02772SucroseGDP-mannose 6-dehydrogenasetarget
DB02772SucroseActin, alpha skeletal muscletarget
DB02772SucroseBeta-glucosidasetarget
DB02772SucroseAmylosucrasetarget
DB02772SucroseBeta-lactamasetarget
DB02772SucroseBeta-lactamase CTX-Mtarget
DB02772SucroseHeme oxygenasetarget
DB02772SucroseCopper transport protein ATOX1target
DB02772SucrosetRNA-splicing ligase RtcB homologtarget
DB02772SucroseOrange carotenoid-binding proteintarget
DB02772SucroseSucrose porintarget
DB02772SucroseLevansucrasetarget
DB02772SucroseBeta-lactamase CTX-M-27target
DB02772SucroseTaste receptor type 1 member 2target
DB03323MaltoseCyclomaltodextrin glucanotransferasetarget
DB03323MaltoseAlpha-amylase 2Btarget
DB03323MaltoseBeta-amylasetarget
DB03323MaltoseMaltogenic alpha-amylasetarget
DB03323MaltoseMaltodextrin phosphorylasetarget
DB03323MaltoseMaltose-binding periplasmic proteintarget
DB03323MaltoseAlpha-glucosidasetarget
DB03323MaltoseMaltose binding proteintarget
DB03323MaltoseMalto-oligosyltrehalose trehalohydrolasetarget
DB03793Benzoic AcidPeroxiredoxin-5, mitochondrialtarget
DB03793Benzoic AcidHeat-labile enterotoxin B chaintarget
DB03793Benzoic AcidCocaine esterasetarget
DB03793Benzoic AcidHTH-type transcriptional regulator MalTtarget
DB03793Benzoic AcidTautomerase PptAtarget
DB03793Benzoic AcidD-amino-acid oxidasetarget
DB03793Benzoic AcidRibonuclease UK114target
DB03793Benzoic AcidChlorocatechol 1,2-dioxygenasetarget
DB03793Benzoic AcidRas-related protein Rab-9Atarget
DB03793Benzoic AcidHydrogen peroxide-inducible genes activatortarget
DB03793Benzoic Acid2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget
DB03793Benzoic AcidNon-heme chloroperoxidasetarget
DB03793Benzoic AcidOxygen-insensitive NAD(P)H nitroreductasetarget
DB03793Benzoic AcidHydroxyquinol 1,2-dioxygenasetarget
DB03793Benzoic AcidReplication proteintarget
DB03793Benzoic AcidSolute carrier organic anion transporter family member 2B1transporter
DB03793Benzoic AcidSolute carrier family 22 member 8transporter
DB03793Benzoic AcidMonocarboxylate transporter 1transporter
DB03793Benzoic AcidSolute carrier family 15 member 1target
DB04173FructoseBis(5'-adenosyl)-triphosphatasetarget
DB04173FructoseMaltoporintarget
DB04465LactoseBeta-galactosidasetarget
DB04465LactoseTetanus toxintarget
DB04465LactoseGlycosyltransferase 6 domain-containing protein 1target
DB04465LactoseGlycolipid transfer proteintarget
DB04465LactoseEnterotoxin type Btarget
DB04465LactoseSialidasetarget
DB04465LactoseHydrolasetarget
DB04465LactoseEndo-1,4-beta-xylanase Atarget
DB04465LactoseGalectin-3target
DB09112Sodium NitriteHemoglobin subunit alphatarget
DB09112Sodium NitriteHemoglobin subunit betatarget
DB09112Sodium NitriteMyoglobintarget
DB09341GlucoseGlucokinaseenzyme
DB09341GlucoseHexokinase-1enzyme
DB09341GlucoseSolute carrier family 2, facilitated glucose transporter member 1transporter
DB09341GlucoseSolute carrier family 2, facilitated glucose transporter member 2transporter
DB09341GlucoseSolute carrier family 2, facilitated glucose transporter member 3transporter
DB09341GlucoseSolute carrier family 2, facilitated glucose transporter member 4transporter
DB09341GlucoseSolute carrier family 2, facilitated glucose transporter member 6transporter
DB09341GlucoseSolute carrier family 2, facilitated glucose transporter member 7transporter
DB09341GlucoseSolute carrier family 2, facilitated glucose transporter member 8transporter
DB09341GlucoseSolute carrier family 2, facilitated glucose transporter member 9transporter
DB09341GlucoseSolute carrier family 2, facilitated glucose transporter member 10transporter
DB09341GlucoseSolute carrier family 2, facilitated glucose transporter member 11transporter
DB09341GlucoseSolute carrier family 2, facilitated glucose transporter member 12transporter
DB09341GlucoseSodium/glucose cotransporter 1transporter
DB11093Calcium CitrateTransient receptor potential cation channel subfamily V member 6transporter
DB11093Calcium CitrateCalbindincarrier
DB11093Calcium CitrateProtein S100-Gcarrier
DB11093Calcium CitrateSodium/calcium exchanger 1transporter
DB11093Calcium CitrateTransient receptor potential cation channel subfamily V member 5transporter
DB11093Calcium CitrateExtracellular calcium-sensing receptortarget
DB11093Calcium CitrateCalreticulintarget
DB11093Calcium CitrateCalcium and integrin-binding protein 1target
DB11093Calcium CitrateProgrammed cell death protein 6target
DB11093Calcium CitrateSorcintarget
DB11093Calcium CitrateCalcineurin B homologous protein 1target
DB11093Calcium CitrateSPARCtarget
DB11093Calcium CitrateCalnexintarget
DB11093Calcium CitrateFibrillin-2target
DB11093Calcium CitrateProtein S100-Btarget
DB11093Calcium CitrateCalsequestrin-2target
DB11093Calcium CitrateRegucalcintarget
DB11093Calcium CitratePeflintarget
DB11093Calcium CitrateProtein S100-A6target
DB11093Calcium CitrateTranslationally-controlled tumor proteintarget
DB11093Calcium CitrateCalcium and integrin-binding family member 2target
DB11093Calcium CitrateProtein S100-A13target
DB11093Calcium CitrateCalsequestrin-1target
DB11093Calcium CitrateNucleobindin-1target
DB11093Calcium CitrateNucleobindin-2target
DB11093Calcium CitrateCalmodulintarget
DB11093Calcium CitrateFibrillin-3target
DB11093Calcium CitrateGrancalcintarget
DB11093Calcium CitrateCalcium-dependent secretion activator 1target
DB11093Calcium CitrateSerum albumincarrier
DB11093Calcium CitrateCalmodulin-2target
DB11093Calcium CitrateCalmodulin-3target
DB11093Calcium CitrateProtein S100-A16target
DB11093Calcium CitrateCalretinintarget
DB11093Calcium CitrateCalcyphosintarget
DB11093Calcium CitrateCalcium-dependent secretion activator 2target
DB11093Calcium CitrateCalreticulin-3target
DB11093Calcium CitrateRyanodine receptor 1transporter
DB11093Calcium CitrateRyanodine receptor 2transporter
DB11093Calcium CitratePolycystic kidney disease 2-like 1 proteintransporter
DB11093Calcium CitrateNeurexin-1target
DB11093Calcium CitrateNeuronal calcium sensor 1target
DB11093Calcium CitrateRyanodine receptor 3transporter
DB11093Calcium CitratePolycystic kidney disease protein 1-like 3transporter
DB11093Calcium CitrateCation channel sperm-associated protein 1transporter
DB11093Calcium CitrateVoltage dependent L type calcium channeltransporter
DB11093Calcium CitrateVoltage-dependent P/Q-type calcium channeltransporter
DB11093Calcium CitrateVoltage-dependent T-type calcium channeltransporter
DB11093Calcium CitrateVoltage-dependent R-type calcium channeltransporter
DB12418SaccharinCarbonic anhydrase 3target