- Accession Number
Twenty-carbon compounds derived from MEVALONIC ACID or deoxyxylulose phosphate.
Drug Drug Description Menadione The primary known function of vitamin K is to assist in the normal clotting of blood, but it may also play a role in normal bone calcification. Phylloquinone A fat soluble vitamin used to treat hemorrhagic conditions in infants and coumarin overdoses. Paclitaxel A taxoid chemotherapeutic agent used as first-line and subsequent therapy for the treatment of advanced carcinoma of the ovary, and other various cancers including breast and lung cancer. Docetaxel A taxoid antineoplastic agent used in the treatment of various cancers, such as locally advanced or metastatic breast cancer, metastatic prostate cancer, gastric adenocarcinoma, and head and neck cancer. Carboxyatractyloside Not Available Colforsin Potent activator of the adenylate cyclase system and the biosynthesis of cyclic AMP. From the plant Coleus forskohlii. Has antihypertensive, positive inotropic, platelet aggregation inhibitory, and smooth muscle relaxant activities;... Ecabet For the treatment of reflux oesophagitis and peptic ulcer disease. Paclitaxel docosahexaenoic acid Investigated for use/treatment in breast cancer, colorectal cancer, gastric cancer, kidney cancer, lung cancer, pancreatic cancer, prostate cancer, and skin cancer. AI-850 Investigated for use/treatment in breast cancer and solid tumors. Paclitaxel trevatide Investigated for use/treatment in brain cancer. Ginkgolide A Ginkgolide A is a highly active PAF antagonist cage molecule that is isolated from the leaves of the Ginkgo biloba tree. Shows potential in a wide variety of inflammatory and... ginkgolide-C Not Available ginkgolide-J Not Available Cabazitaxel An antineoplastic agent used for the treatment of hormone-refractory metastatic prostate cancer previously treated with a docetaxel-containing treatment regimen. Gibberellic acid Not Available Gibberellin A4 Not Available Ortataxel Ortataxel has been used in trials studying the treatment of Lymphoma, Lung Cancer, Glioblastoma, and Kidney Cancer. Tesetaxel Tesetaxel has been used in trials studying the treatment of Cancer, Melanoma, Prostate Cancer, Gastric Carcinoma, and Advanced Melanoma, among others. Menatetrenone Menatetrenone has been used in trials studying the treatment of Diabetes, Osteoporosis, Prediabetic State, and Hepatocellular Carcinoma. Salvinorin A Salvinorin A has been investigated for the basic science of Pharmaceutical Preparations. Milataxel Milataxel has been used in trials studying the treatment of Mesothelioma. Steviolbioside Steviolbioside has been used in trials studying the treatment of HIV-1 Infection. BMS-188797 BMS-188797 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific. BMS-184476 BMS-184476 has been used in trials studying the treatment of Unspecified Adult Solid Tumor, Protocol Specific. Larotaxel Larotaxel has been used in trials studying the treatment of Cancer, Metastases, Breast Cancer, Breast Neoplasms, and Pancreatic Neoplasms, among others. Menaquinone 7 Menaquinone 7 is under investigation in clinical trial NCT00402974 (The Effect of Vitamin K Supplementation on Osteocalcin Carboxylation in Healthy Children). Paclitaxel poliglumex Not Annotated Menadiol diphosphate Not Annotated Menaquinone 6 Menaquinone 6 is under investigation in clinical trial NCT01194778 (Comparison of Efficacy of Different Dosages Vitamin K2). Rebaudioside A Rebaudioside A is under investigation in clinical trial NCT03510624 (Acute Effect of Rebaudioside A on Glucose Excursion During an Oral Glucose Tolerance Test in Type 2 Diabetes Mellitus). Menaquinone Menaquinone is under investigation in clinical trial NCT01533441 (Vitamin K2 Intervention in Patients With Vitamin K Antagonists). Simotaxel Simotaxel is under investigation in clinical trial NCT00088647 (Study Evaluating MST-997 in Advanced Malignant Solid Tumors).
- Drugs & Drug Targets