Name
Lignans
Accession Number
DBCAT000416
Description

A class of dibenzylbutane derivatives which occurs in higher plants and in fluids (bile, serum, urine, etc.) in man and other animals. These compounds, which have a potential anti-cancer role, can be synthesized in vitro by human fecal flora. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)

Drugs
DrugDrug Description
PodofiloxA topical agent used for the treatment of external genital warts and perianal warts.
MasoprocolUsed for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).
TerameprocolTerameprocol has been investigated for the treatment of Brain and Central Nervous System Tumors.
PicropodophyllinPicropodophyllin has been investigated for the treatment of Non Small Cell Lung Cancer.
Drugs & Drug Targets
DrugTargetType
PodofiloxDNA topoisomerase 2-alphatarget
PodofiloxTubulin alpha-4A chaintarget
PodofiloxTubulin beta chaintarget
MasoprocolArachidonate 5-lipoxygenasetarget
MasoprocolSex hormone-binding globulintarget
MasoprocolTransient receptor potential cation channel subfamily M member 7target