Name
Catechols
Accession Number
DBCAT000419
Description

A group of 1,2-benzenediols that contain the general formula R-C6H5O2.

Drugs
DrugDrug Description
MasoprocolUsed for the treatment of actinic keratoses (precancerous skin growths that can become malignant if left untreated).
MethocarbamolA CNS depressant indicated with rest, physical therapy and other treatments to control the discomfort associated with various acute musculoskeletal conditions.
GuaifenesinAn expectorant commonly found in OTC products for the symptomatic relief from congested chests and coughs associated with cold, bronchitis, and/or other breathing illnesses.
CapsaicinA topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
ZucapsaicinA topical analgesic used as an adjunct to relieve severe pain of osteoarthritis of the knee in selected adult patients.
NonivamideNonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , .
GuaiacolIt is used medicinally as an expectorant, antiseptic, and local anesthetic. Guaiacol is used in traditional dental pulp sedation, and has the property of inducing cell proliferation; guaiacol is a...
CurcuminNo approved therapeutic indications.
TerameprocolTerameprocol has been investigated for the treatment of Brain and Central Nervous System Tumors.
Potassium GuaiacolsulfonateGuaiacolsulfonate is an aromatic sulfonic acid. Potassium guaiacolsulfonate salt is an expectorant that thins the mucus in the lungs and reduces chest congestion.
DihydrocapsiateDihydrocapsiate is under investigation in clinical trial NCT00999297 (Effect of 4-week Dihydrocapsiate Ingestion on Resting Metabolic Rate).
AmphetamineA CNS stimulant and sympathomimetic agent indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD).
CarbidopaA dopa decarboxylase inhibitor used in combination with levodopa for the symptomatic treatment of idiopathic Parkinson disease and other conditions associated with parkinsonian symptoms.
NorepinephrineA sympathomimetic used in the control of blood pressure during various hypotensive states and as an adjunct treatment during cardiac arrest.
AlprazolamA long-acting benzodiazepine with intermediate onset commonly used to treat panic disorders and generalized anxiety in addition to anxiety associated with depression.
DipivefrinA prodrug of epinephrine used in ophthalmic solutions to reduce intraocular pressure in chronic open-angle glaucoma.
EpinephrineA hormone and neurotransmitter used to treat allergic reactions, to restore cardiac rhythm, and to control mucosal congestion, glaucoma, and asthma.
OrciprenalineA beta-2 adrenergic agonist used to treat bronchospasm, asthma, and COPD.
DobutamineA beta-1 agonist used to treat cardiac decompensation in patients with organic heart disease or from cardiac surgery.
MethyldopaAn alpha-2 adrenergic agonist used to treat hypertension.
DopamineA catecholamine neurotransmitter used to treat hemodynamic imbalances, poor perfusion of vital organs, low cardiac output, and hypotension.
IsoprenalineA non-selective beta-adrenergic agonist typically used to treat bradycardia and heart block; it is structurally related to epinephrine.
ArbutamineUsed to elicit acute cardiovascular responses (cardiac stumulant), similar to those produced by exercise, in order to aid in diagnosing the presence or absence of coronary artery disease (CAD) in...
LevodopaA dopamine precursor used in the management of Parkinson's disease, often in combination with carbidopa, as well as other conditions associated with parkinsonism.
FenoterolA beta-2 adrenergic agonist and bronchodilator used for the symptomatic treatment of asthma.
6-hydroxydopa quinoneNot Available
DroxidopaA medication used to treat symptomatic neurogenic orthostatic hypotension (nOH) caused by dopamine beta-hydroxylase deficiency, non-diabetic autonomic neuropathy and primary autonomic failure caused by conditions such as Parkinson's disease.
EtilevodopaInvestigated for use/treatment in parkinson's disease.
LevonordefrinA topical sympathomimetic amine found in local anesthetic products that is used for nasal decongestion or vasoconstriction during dental procedures.
ProtokylolProtokylol is a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States.
RacepinephrineA bronchodilator used to treat intermittent asthma.
DopexamineDopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer.
DichloroisoproterenolDichloroisoproterenol has been used in trials studying the treatment and basic science of Insulin Resistance and Polycystic Ovary Syndrome.
ReproterolReproterol has been used in trials studying the treatment of Asthma, Exercise-Induced.
TheodrenalineTheodrenaline is under investigation in clinical trial NCT01311414 (Effect of Cafedrine/Theodrenaline and Urapidil on Cerebral Oxygenation).
MelevodopaNot Annotated
IbopamineNot Annotated
AdrenaloneNot Annotated
Fluorodopa (18F)Fluorodopa F 18 is indicated for use with positron emission tomography (PET) to visualize dopaminergic nerve terminals in the striatum for the evaluation of adult patients with suspected Parkinsonian syndromes...
DeoxyepinephrineSympathomimetic, vasoconstrictor agent.
J147J147 is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging. [A31606,A31607,A31608] It is a curcumin derivative and a potent neurogenic...
ZingeroneZingerone is a pungent component of ginger.
4-VinylguaiacolNot Available
Drugs & Drug Targets
DrugTargetType
MasoprocolArachidonate 5-lipoxygenasetarget
MasoprocolArachidonate 5-lipoxygenaseenzyme
MasoprocolSex hormone-binding globulintarget
MethocarbamolCarbonic anhydrase 1target
GuaifenesinNMDA receptortarget
CapsaicinCytochrome P450 3A4enzyme
CapsaicinProstaglandin G/H synthase 2enzyme
CapsaicinMyeloperoxidaseenzyme
CapsaicinCytochrome P450 1A2enzyme
CapsaicinCytochrome P450 2E1enzyme
CapsaicinAmine oxidase [flavin-containing] Aenzyme
CapsaicinDopamine beta-hydroxylaseenzyme
CapsaicinGlutamine synthetaseenzyme
CapsaicinCholinesteraseenzyme
CapsaicinTransient receptor potential cation channel subfamily V member 1target
CapsaicinProhibitin-2target
ZucapsaicinTransient receptor potential cation channel subfamily V member 1target
ZucapsaicinCytochrome P450 1A2enzyme
ZucapsaicinCytochrome P450 2C19enzyme
ZucapsaicinCytochrome P450 2C9enzyme
ZucapsaicinCytochrome P450 2E1enzyme
NonivamideTransient receptor potential cation channel subfamily V member 1target
GuaiacolSerum albumintarget
CurcuminPeroxisome proliferator-activated receptor gammatarget
CurcuminVitamin D3 receptortarget
CurcuminMultidrug resistance-associated protein 5target
CurcuminCarbonyl reductase [NADPH] 1target
CurcuminGlutathione S-transferase Ptarget
CurcuminCytochrome P450 2C9enzyme
CurcuminCytochrome P450 3A4enzyme
CurcuminCytochrome P450 2B6enzyme
CurcuminCytochrome P450 1A2enzyme
CurcuminCytochrome P450 2D6enzyme
CurcuminGlutathione S-transferase A1enzyme
CurcuminGlutathione S-transferase Mu 1enzyme
CurcuminGlutathione S-transferase Penzyme
CurcuminP-glycoprotein 1transporter
AmphetamineSodium-dependent dopamine transportertarget
AmphetamineCocaine- and amphetamine-regulated transcript proteintarget
AmphetamineTrace amine-associated receptor 1target
AmphetamineCytochrome P450 2D6enzyme
AmphetamineSolute carrier family 22 member 3transporter
AmphetamineSolute carrier family 22 member 5transporter
AmphetamineSynaptic vesicular amine transportertarget
AmphetamineCytochrome P450 2A6enzyme
AmphetamineSodium-dependent noradrenaline transportertarget
AmphetamineAlpha adrenergic receptortarget
AmphetamineBeta adrenergic receptortarget
AmphetamineDopamine D2 receptortarget
AmphetamineAmine oxidase [flavin-containing] Btarget
AmphetamineSodium-dependent serotonin transportertarget
AmphetamineMonoamine oxidasetarget
Amphetaminevesicular monoamine transporter 2 (VMAT2)target
CarbidopaAromatic-L-amino-acid decarboxylasetarget
NorepinephrinePhenylalanine-4-hydroxylasetarget
NorepinephrineAlpha-1A adrenergic receptortarget
NorepinephrineAlpha-1B adrenergic receptortarget
NorepinephrineAlpha-1D adrenergic receptortarget
NorepinephrineAlpha-2A adrenergic receptortarget
NorepinephrineAlpha-2B adrenergic receptortarget
NorepinephrineAlpha-2C adrenergic receptortarget
NorepinephrineBeta-1 adrenergic receptortarget
NorepinephrineBeta-2 adrenergic receptortarget
NorepinephrineBeta-3 adrenergic receptortarget
NorepinephrineSolute carrier family 22 member 2transporter
NorepinephrineSolute carrier family 22 member 3transporter
NorepinephrineSolute carrier family 22 member 5transporter
NorepinephrineSolute carrier family 22 member 1transporter
NorepinephrinePOU domain, class 5, transcription factor 1transporter
NorepinephrineSodium-dependent noradrenaline transportertransporter
NorepinephrineSynaptic vesicular amine transportertarget
NorepinephrineChromaffin granule amine transportertarget
AlprazolamCytochrome P450 3A4enzyme
AlprazolamCytochrome P450 2C9enzyme
AlprazolamCytochrome P450 3A5enzyme
AlprazolamCytochrome P450 3A7enzyme
AlprazolamGABA(A) Receptortarget
AlprazolamSerum albumincarrier
Alprazolamalpha1-acid glycoproteincarrier
AlprazolamGABA(A) Receptor Benzodiazepine Binding Sitetarget
DipivefrinAlpha-2A adrenergic receptortarget
DipivefrinCholinesterasetarget
DipivefrinBeta-2 adrenergic receptortarget
DipivefrinAlpha-1A adrenergic receptortarget
DipivefrinAcetylcholinesterasetarget
EpinephrineAlpha-1A adrenergic receptortarget
EpinephrineBeta-1 adrenergic receptortarget
EpinephrineBeta-2 adrenergic receptortarget
EpinephrineSolute carrier family 22 member 2transporter
EpinephrineSolute carrier family 22 member 1transporter
EpinephrineCytochrome P450 2C9enzyme
EpinephrineCytochrome P450 3A4enzyme
EpinephrineAlpha-1B adrenergic receptortarget
EpinephrineAlpha-1D adrenergic receptortarget
EpinephrineAlpha-2A adrenergic receptortarget
EpinephrineAlpha-2B adrenergic receptortarget
EpinephrineTumor necrosis factortarget
EpinephrineCatechol O-methyltransferaseenzyme
EpinephrineMonoamine oxidaseenzyme
OrciprenalineBeta-2 adrenergic receptortarget
DobutamineBeta-1 adrenergic receptortarget
DobutamineCatechol O-methyltransferaseenzyme
DobutamineBeta-2 adrenergic receptortarget
DobutamineAlpha-1 adrenergic receptorstarget
DobutamineEstrogen receptor alphatarget
MethyldopaAlpha-2A adrenergic receptortarget
MethyldopaCatechol O-methyltransferaseenzyme
MethyldopaSolute carrier family 15 member 1transporter
MethyldopaAromatic-L-amino-acid decarboxylasetarget
DopamineDopamine D1 receptortarget
DopamineDopamine beta-hydroxylasetarget
DopamineAmine oxidase [flavin-containing] Aenzyme
DopamineAmine oxidase [flavin-containing] Benzyme
DopamineCatechol O-methyltransferaseenzyme
DopamineSolute carrier family 22 member 2transporter
DopamineSolute carrier family 22 member 1transporter
DopamineSolute carrier family 22 member 3transporter
DopamineSolute carrier family 22 member 5transporter
DopaminePOU domain, class 5, transcription factor 1transporter
DopamineDopamine D5 receptortarget
DopamineDopamine D2 receptortarget
DopamineDopamine D3 receptortarget
DopamineDopamine D4 receptortarget
DopamineSodium-dependent dopamine transportertarget
DopamineDopamine beta-hydroxylaseenzyme
Dopamine5-hydroxytryptamine receptor 1Atarget
Dopamine5-hydroxytryptamine receptor 7target
DopamineD(1) dopamine receptortarget
DopamineSodium-dependent noradrenaline transportertarget
DopamineSodium-dependent serotonin transportertarget
Dopamine5-hydroxytryptamine receptor 3Atarget
Dopamine5-hydroxytryptamine receptor 3Btarget
DopamineSuperoxide dismutase [Cu-Zn]target
DopamineSynaptic vesicular amine transportertarget
IsoprenalineBeta-1 adrenergic receptortarget
IsoprenalineBeta-2 adrenergic receptortarget
IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit alphatarget
IsoprenalineBeta-3 adrenergic receptortarget
IsoprenalineMitogen-activated protein kinase 1target
IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit betatarget
IsoprenalinePhosphatidylinositol 3-kinase regulatory subunit gammatarget
IsoprenalineCytochrome P450 1A1enzyme
IsoprenalineCAMP phosphodiesterasetarget
IsoprenalineSuperoxide dismutase [Cu-Zn]target
ArbutamineBeta-1 adrenergic receptortarget
ArbutamineBeta-2 adrenergic receptortarget
ArbutamineBeta-3 adrenergic receptortarget
LevodopaDopamine D1 receptortarget
LevodopaDopamine D2 receptortarget
LevodopaAromatic-L-amino-acid decarboxylaseenzyme
LevodopaSolute carrier family 15 member 1transporter
LevodopaMonocarboxylate transporter 10transporter
LevodopaDopamine D3 receptortarget
LevodopaDopamine D4 receptortarget
LevodopaDopamine D5 receptortarget
LevodopaLarge neutral amino acids transporter small subunit 1transporter
LevodopaLarge neutral amino acids transporter small subunit 2transporter
LevodopaSerum albumincarrier
FenoterolBeta-2 adrenergic receptortarget
FenoterolBeta-1 adrenergic receptortarget
FenoterolBeta-3 adrenergic receptortarget
6-hydroxydopa quinoneMembrane primary amine oxidasetarget
6-hydroxydopa quinonePrimary amine oxidasetarget
6-hydroxydopa quinonePhenylethylamine oxidasetarget
DroxidopaPhenylalanine-4-hydroxylasetarget
DroxidopaAlpha-1A adrenergic receptortarget
DroxidopaAlpha-1B adrenergic receptortarget
DroxidopaAlpha-1D adrenergic receptortarget
DroxidopaAlpha-2A adrenergic receptortarget
DroxidopaAlpha-2B adrenergic receptortarget
DroxidopaAlpha-2C adrenergic receptortarget
DroxidopaBeta-1 adrenergic receptortarget
DroxidopaBeta-2 adrenergic receptortarget
DroxidopaBeta-3 adrenergic receptortarget
DroxidopaAromatic-L-amino-acid decarboxylaseenzyme
DroxidopaMonocarboxylate transporter 10transporter
DroxidopaSodium-dependent noradrenaline transportertransporter
LevonordefrinAlpha-2 adrenergic receptorstarget
ProtokylolBeta-2 adrenergic receptortarget
RacepinephrineAlpha-1A adrenergic receptortarget
RacepinephrineAlpha-1B adrenergic receptortarget
RacepinephrineAlpha-2A adrenergic receptortarget
RacepinephrineAlpha-2B adrenergic receptortarget
RacepinephrineAlpha-2C adrenergic receptortarget
RacepinephrineBeta-1 adrenergic receptortarget
RacepinephrineBeta-2 adrenergic receptortarget
RacepinephrineAlpha-1D adrenergic receptortarget
RacepinephrineBeta-3 adrenergic receptortarget
Fluorodopa (18F)Aromatic-L-amino-acid decarboxylaseenzyme