Adrenergic beta-1 Receptor Antagonists

Drugs that bind to and block the activation of ADRENERGIC BETA-1 RECEPTORS.
DrugDrug NameDrug Indication
DB00187EsmololFor the rapid control of ventricular rate in patients with atrial fibrillation or atrial flutter in perioperative, postoperative, or other emergent circumstances where short term control of ventricular rate with a short-acting agent is desirable. Also used in noncompensatory sinus tachycardia where the rapid heart rate requires specific intervention.
DB00195BetaxololFor the management of hypertension.
DB00264MetoprololFor the management of acute myocardial infarction, angina pectoris, heart failure and mild to moderate hypertension. May be used to treat supraventricular and tachyarrhythmias and as prophylaxis for migraine headaches.
DB00335AtenololFor the management of hypertention and long-term management of patients with angina pectoris
DB00612BisoprololFor management of heart failure, angina pectoris, and mild to moderate hypertension and for secondary prevention of myocardial infarction (MI).
DB01193AcebutololFor the management of hypertension and ventricular premature beats in adults.
DB01295BevantololFor the treatment of angina pectoris and hypertension.
DB01297PractololUsed in the emergency treatment of cardiac arrhythmias.
DB04846CeliprololCeliprolol is indicated for the management of mild to moderate hypertension and effort-induced angina pectoris.
DrugDrug NameTargetType
DB00187EsmololBeta-1 adrenergic receptortarget
DB00195BetaxololBeta-1 adrenergic receptortarget
DB00195BetaxololBeta-2 adrenergic receptortarget
DB00195BetaxololCytochrome P450 1A2enzyme
DB00195BetaxololCytochrome P450 2D6enzyme
DB00264MetoprololBeta-1 adrenergic receptortarget
DB00264MetoprololCytochrome P450 2D6enzyme
DB00264MetoprololBeta-2 adrenergic receptortarget
DB00264MetoprololSolute carrier family 22 member 2transporter
DB00264MetoprololMultidrug resistance protein 1transporter
DB00264MetoprololCytochrome P450 2C19enzyme
DB00335AtenololBeta-1 adrenergic receptortarget
DB00335AtenololMultidrug resistance protein 1transporter
DB00335AtenololBeta-2 adrenergic receptortarget
DB00612BisoprololBeta-1 adrenergic receptortarget
DB00612BisoprololBeta-2 adrenergic receptortarget
DB00612BisoprololCytochrome P450 2D6enzyme
DB00612BisoprololCytochrome P450 3A4enzyme
DB01193AcebutololBeta-1 adrenergic receptortarget
DB01193AcebutololCytochrome P450 2D6enzyme
DB01193AcebutololBeta-2 adrenergic receptortarget
DB01193AcebutololSolute carrier family 22 member 1transporter
DB01193AcebutololMultidrug resistance protein 1transporter
DB01295BevantololBeta-1 adrenergic receptortarget
DB01295BevantololBeta-2 adrenergic receptortarget
DB01295BevantololAlpha-1A adrenergic receptortarget
DB01297PractololBeta-1 adrenergic receptortarget
DB04846CeliprololBeta-1 adrenergic receptortarget
DB04846CeliprololCytochrome P450 3A4enzyme
DB04846CeliprololBeta-2 adrenergic receptortarget
DB04846CeliprololBeta-3 adrenergic receptortarget
DB04846CeliprololAlpha-2A adrenergic receptortarget
DB04846CeliprololAlpha-2B adrenergic receptortarget
DB04846CeliprololAlpha-2C adrenergic receptortarget