Fatty Alcohols

Usually high-molecular-weight, straight-chain primary alcohols, but can also range from as few as 4 carbons, derived from natural fats and oils, including lauryl, stearyl, oleyl, and linoleyl alcohols. They are used in pharmaceuticals, cosmetics, detergents, plastics, and lube oils and in textile manufacture. (From McGraw-Hill Dictionary of Scientific and Technical Terms, 5th ed)
DrugDrug NameDrug Description
DB00285VenlafaxineA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression.
DB00464Sodium tetradecyl sulfateAn anionic surfactant used to treat varicose veins of the lower extremities.
DB00815Sodium lauryl sulfateAn anionic surfactant used in cosmetics and pharmaceuticals as a fat emulsifier, wetting agent, and detergent.
DB02509FarnesolA colorless liquid extracted from oils of plants such as citronella, neroli, cyclamen, and tuberose. It is an intermediate step in the biological synthesis of cholesterol from mevalonic acid in...
DB026062-ButanolNot Available
DB03703CyclohexanolMonohydroxy derivatives of cyclohexanes that contain the general formula R-C6H11O. They have a camphorlike odor and are used in making soaps, insecticides, germicides, dry cleaning, and plasticizers. [PubChem]
DB03852EucalyptolA common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion.
DB03967Dodecyl sulfateNot Available
DB04878VogliboseFor the treatment of diabetes. It is specifically used for lowering post-prandial blood glucose levels thereby reducing the risk of macrovascular complications.
DB06700DesvenlafaxineAn antidepressant agent and SNRI used for the treatment of major depressive disorders in adults.
DB11386ChlorobutanolNo approved therapeutic indications on its own.
DB11798TanzisertibTanzisertib has been used in trials studying the treatment of Fibrosis, Discoid Lupus, Pulmonary Fibrosis, Interstitial Lung Disease, and Lung Diseases, Interstitial, among others.
DB11954LomibuvirLomibuvir has been used in trials studying the treatment of Chronic Hepatitis C Virus and Chronic Hepatitis C Virus Infection.
DB12041MapracoratMapracorat has been investigated for the treatment of Eczema and Atopic Dermatitis.
DB12448LifibrolLifibrol has been used in trials studying the basic science of Hyperlipoproteinemia and Hypercholesterolemia.
DB12452Caprylic alcoholCaprylic alcohol has been used in trials studying the treatment of Essential Tremor.
DB12681SalirasibSalirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.
DB13012AQX-1125AQX-1125 has been used in trials studying the treatment of COPD, Atopic Dermatitis, Interstitial Cystitis, and Bladder Pain Syndrome.
DB13163Terpin hydrateAn expectorant used to treat bronchitis, pneumonia, bronchiectasis, COPD, and infectious or inflammatory diseases of the upper respiratory tract.
DB13733MethylpentynolNot Annotated
DB14589Caprylyl glycolNot Annotated
DB02296Isoamyl alcoholNot Available
DB00825LevomentholAn organic compound used to treat mild to moderate muscle and joint pain.
DB068941-Dodecanol1-Dodecanol is a saturated 12-carbon fatty alcohol obtained from coconut oil fatty acids. It has a floral odor and is used in detergents, lubricating oils, and pharmaceuticals. (From McGraw-Hill Dictionary...
DrugDrug NameTargetType
DB00285VenlafaxineSodium-dependent serotonin transportertarget
DB00285VenlafaxineSodium-dependent noradrenaline transportertarget
DB00285VenlafaxineCytochrome P450 2D6enzyme
DB00285VenlafaxineCytochrome P450 3A4enzyme
DB00285VenlafaxineSodium-dependent dopamine transportertarget
DB00285VenlafaxineP-glycoprotein 1transporter
DB00285VenlafaxineATP-binding cassette sub-family G member 2transporter
DB00464Sodium tetradecyl sulfateVitamin K-dependent protein Ctarget
DB00464Sodium tetradecyl sulfateVitamin K-dependent protein Starget
DB00815Sodium lauryl sulfateSerum albumincarrier
DB02509FarnesolAmine oxidase [flavin-containing] Btarget
DB02509FarnesolAmine oxidase [flavin-containing] Benzyme
DB02509FarnesolBile acid receptortarget
DB026062-ButanolNADP-dependent isopropanol dehydrogenasetarget
DB03703CyclohexanolAlcohol dehydrogenase 1Btarget
DB03967Dodecyl sulfateLysozyme Ctarget
DB03967Dodecyl sulfateLipid A palmitoyltransferase PagPtarget
DB04878VogliboseMaltase-glucoamylase, intestinaltarget
DB06700DesvenlafaxineCytochrome P450 3A4enzyme
DB06700DesvenlafaxineSodium-dependent serotonin transportertarget
DB06700DesvenlafaxineSodium-dependent noradrenaline transportertarget
DB06700DesvenlafaxineCytochrome P450 2D6enzyme
DB06700DesvenlafaxineSodium-dependent dopamine transportertarget
DB07895ALPHA-HYDROXYFARNESYLPHOSPHONIC ACIDProtein farnesyltransferase subunit betatarget
DB07895ALPHA-HYDROXYFARNESYLPHOSPHONIC ACIDProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alphatarget
DB11386ChlorobutanolPotassium voltage-gated channel subfamily H member 2target
DB02296Isoamyl alcoholRenintarget
DB00825LevomentholTransient receptor potential cation channel subfamily A member 1target
DB00825LevomentholTransient receptor potential cation channel subfamily M member 8target
DB00825LevomentholTransient receptor potential cation channel subfamily V member 3target
DB00825LevomentholKappa-type opioid receptortarget
DB00825LevomentholVoltage-dependent L-type calcium channeltarget
DB00825LevomentholCytochrome P450 3A4enzyme
DB068941-DodecanolSDS hydrolase SdsA1target
DB068941-DodecanolFatty-acid amide hydrolase 1target