Phosphodiesterase 5 Inhibitors

Name
Phosphodiesterase 5 Inhibitors
Accession Number
DBCAT000518
Description

Compounds that specifically inhibit PHOSPHODIESTERASE 5.

Drugs
DrugDrug Description
SildenafilA phosphodiesterase inhibitor used for the treatment of erectile dysfunction.
TadalafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction, benign prostatic hyperplasia, and pulmonary arterial hypertension.
VardenafilA phosphodiesterase 5 inhibitor used to treat erectile dysfunction.
UdenafilInvestigated for use/treatment in erectile dysfunction and hypertension.
MirodenafilMirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction.
AvanafilA phosphodiesterase 5 (PDE5) inhibitor used to treat erectile dysfunction.
DipyridamoleA phosphodiesterase inhibitor used to prevent postoperative thromboembolic events.
PentoxifyllineA methylxanthine derivative used to treat intermittent claudication caused by chronic occlusive arterial disease of the limbs.
TheophyllineA xanthine used to manage the symptoms of asthma, COPD, and other lung conditions caused by reversible airflow obstruction.
FostamatinibA spleen tyrosine kinase inhibitor used to treat chronic immune thrombocytopenia after attempting one other treatment.
MilrinoneAn inotropic vasodilator agent used to treat acute, decompensated heart failure.
IbudilastFor the treatment of multiple sclerosis, asthma, and cerebrovascular disease.
DoxofyllineIndicated for the treatment of chronic obstructive pulmonary disease (COPD), bronchial asthma and pulmonary disease with spastic bronchial component.
Drugs & Drug Targets
DrugTargetType
SildenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
SildenafilCytochrome P450 2C9enzyme
SildenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
SildenafilCytochrome P450 3A4enzyme
SildenafilCytochrome P450 3A5enzyme
SildenafilCytochrome P450 3A7enzyme
SildenafilMultidrug resistance-associated protein 4transporter
SildenafilMultidrug resistance-associated protein 5transporter
SildenafilMultidrug resistance-associated protein 7transporter
SildenafilCytochrome P450 2C19enzyme
SildenafilCytochrome P450 2D6enzyme
SildenafilCytochrome P450 2E1enzyme
SildenafilSolute carrier organic anion transporter family member 1B1transporter
SildenafilP-glycoprotein 1transporter
TadalafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
TadalafilCytochrome P450 3A4enzyme
TadalafilDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11Atarget
TadalafilCytochrome P450 3A5enzyme
VardenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
VardenafilCytochrome P450 3A4enzyme
VardenafilRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilRetinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gammatarget
VardenafilCytochrome P450 3A5enzyme
VardenafilP-glycoprotein 1transporter
UdenafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
UdenafilCytochrome P450 3A4enzyme
UdenafilCytochrome P450 3A5enzyme
MirodenafilCytochrome P450 3A Subfamilyenzyme
AvanafilcGMP-specific 3',5'-cyclic phosphodiesterasetarget
AvanafilCytochrome P450 3A4enzyme
DipyridamolecAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DipyridamolecGMP-specific 3',5'-cyclic phosphodiesterasetarget
DipyridamolecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DipyridamoleAdenosine deaminasetarget
DipyridamoleMultidrug resistance-associated protein 4transporter
DipyridamoleMultidrug resistance-associated protein 5transporter
DipyridamoleP-glycoprotein 1transporter
DipyridamoleCalcipressin-1target
DipyridamoleAlpha-1-acid glycoprotein 1target
DipyridamoleSolute carrier organic anion transporter family member 1B1transporter
DipyridamoleSolute carrier organic anion transporter family member 1B3transporter
DipyridamoleSolute carrier organic anion transporter family member 2B1transporter
DipyridamoleBile salt export pumptransporter
Pentoxifylline5'-nucleotidasetarget
PentoxifyllineAdenosine receptor A1target
PentoxifyllineAdenosine receptor A2atarget
PentoxifyllineCytochrome P450 1A2enzyme
PentoxifyllinePhosphodiesterase enzymestarget
TheophyllinecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
TheophyllineAdenosine receptor A2btarget
TheophyllinecAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
TheophyllinecGMP-specific 3',5'-cyclic phosphodiesterasetarget
TheophyllineAdenosine receptor A1target
TheophyllineAdenosine receptor A2atarget
TheophyllineCytochrome P450 1A2enzyme
TheophyllineAdenosine deaminaseenzyme
TheophyllineCytochrome P450 2E1enzyme
TheophyllineCytochrome P450 3A4enzyme
TheophyllineSolute carrier family 22 member 7transporter
TheophyllineCytochrome P450 1A1enzyme
TheophyllineCytochrome P450 1B1enzyme
TheophyllineCytochrome P450 2D6enzyme
TheophyllineHistone deacetylase 2target
TheophyllineCopine-1target
TheophyllineMinor histocompatibility antigen H13target
TheophyllineNodal modulator 1target
TheophyllinePoly [ADP-ribose] polymerase 1target
TheophyllineProtein RIC-3target
TheophyllineTubulin monoglycylase TTLL3target
FostamatinibAdenosine receptor A3target
Fostamatinibvesicular monoamine transporter 2 (VMAT2)target
FostamatinibFatty-acid amide hydrolase 1target
FostamatinibEquilibrative nucleoside transporter 1target
FostamatinibUDP-glucuronosyltransferase 1-1target
FostamatinibcGMP-specific 3',5'-cyclic phosphodiesterasetarget
FostamatinibArachidonate 5-lipoxygenasetarget
FostamatinibCathepsin Starget
FostamatinibCathepsin L1target
FostamatinibTyrosine-protein kinase ABL1target
FostamatinibCalcium-dependent protein kinase 1target
FostamatinibSerine/threonine-protein kinase PknBtarget
FostamatinibRibosomal protein S6 kinase alpha-6target
FostamatinibNon-receptor tyrosine-protein kinase TYK2target
FostamatinibAtypical kinase COQ8A, mitochondrialtarget
FostamatinibTyrosine-protein kinase JAK1target
FostamatinibHepatocyte growth factor receptortarget
FostamatinibSerine/threonine-protein kinase NIM1target
FostamatinibSerine/threonine-protein kinase MST4target
FostamatinibcAMP-dependent protein kinase catalytic subunit alphatarget
FostamatinibSerine/threonine-protein kinase 24target
FostamatinibSerine/threonine-protein kinase 3target
FostamatinibTyrosine-protein kinase Tectarget
FostamatinibTyrosine-protein kinase SYKtarget
FostamatinibSerine/threonine-protein kinase 33target
FostamatinibSerine/threonine-protein kinase 35target
FostamatinibSerine/threonine-protein kinase 36target
FostamatinibSerine/threonine-protein kinase 38target
FostamatinibSerine/threonine-protein kinase 38-liketarget
FostamatinibSTE20/SPS1-related proline-alanine-rich protein kinasetarget
FostamatinibSerine/threonine-protein kinase TAO1target
FostamatinibSerine/threonine-protein kinase TAO2target
FostamatinibSerine/threonine-protein kinase TAO3target
FostamatinibSerine/threonine-protein kinase TBK1target
FostamatinibAngiopoietin-1 receptortarget
FostamatinibDual specificity testis-specific protein kinase 1target
FostamatinibTGF-beta receptor type-1target
FostamatinibTGF-beta receptor type-2target
FostamatinibTyrosine-protein kinase receptor Tie-1target
FostamatinibSerine/threonine-protein kinase tousled-like 1target
FostamatinibSerine/threonine-protein kinase tousled-like 2target
FostamatinibTRAF2 and NCK-interacting protein kinasetarget
FostamatinibNon-receptor tyrosine-protein kinase TNK1target
FostamatinibActivated CDC42 kinase 1target
FostamatinibSerine/threonine-protein kinase TNNI3Ktarget
FostamatinibTestis-specific serine/threonine-protein kinase 1target
FostamatinibDual specificity protein kinase TTKtarget
FostamatinibTyrosine-protein kinase TXKtarget
FostamatinibTyrosine-protein kinase receptor TYRO3target
FostamatinibSerine/threonine-protein kinase ULK1target
FostamatinibSerine/threonine-protein kinase ULK2target
FostamatinibSerine/threonine-protein kinase ULK3target
FostamatinibWee1-like protein kinasetarget
FostamatinibTyrosine-protein kinase Yestarget
FostamatinibMitogen-activated protein kinase kinase kinase 19target
FostamatinibMitogen-activated protein kinase kinase kinase MLTtarget
FostamatinibTyrosine-protein kinase ZAP-70target
FostamatinibAP2-associated protein kinase 1target
FostamatinibAbelson tyrosine-protein kinase 2target
FostamatinibActivin receptor type-1target
FostamatinibActivin receptor type-1Btarget
FostamatinibAtypical kinase COQ8B, mitochondrialtarget
FostamatinibALK tyrosine kinase receptortarget
FostamatinibAnkyrin repeat and protein kinase domain-containing protein 1target
FostamatinibAurora kinase Atarget
FostamatinibAurora kinase Btarget
FostamatinibAurora kinase Ctarget
FostamatinibTyrosine-protein kinase receptor UFOtarget
FostamatinibTyrosine-protein kinase Blktarget
FostamatinibBMP-2-inducible protein kinasetarget
FostamatinibBone morphogenetic protein receptor type-1Btarget
FostamatinibBone morphogenetic protein receptor type-2target
FostamatinibCytoplasmic tyrosine-protein kinase BMXtarget
FostamatinibSerine/threonine-protein kinase B-raftarget
FostamatinibTyrosine-protein kinase BTKtarget
FostamatinibCalcium/calmodulin-dependent protein kinase type 1target
FostamatinibCalcium/calmodulin-dependent protein kinase type 1Dtarget
FostamatinibCalcium/calmodulin-dependent protein kinase type 1Gtarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit alphatarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit betatarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit deltatarget
FostamatinibCalcium/calmodulin-dependent protein kinase type II subunit gammatarget
FostamatinibCalcium/calmodulin-dependent protein kinase kinase 1target
FostamatinibCalcium/calmodulin-dependent protein kinase kinase 2target
FostamatinibPeripheral plasma membrane protein CASKtarget
FostamatinibKappa-caseintarget
FostamatinibCyclin-dependent kinase 1target
FostamatinibSerine/threonine-protein kinase MRCK gammatarget
FostamatinibCyclin-dependent kinase 4target
FostamatinibCyclin-dependent kinase-like 1target
FostamatinibCyclin-dependent kinase-like 2target
FostamatinibSerine/threonine-protein kinase Chk1target
FostamatinibSerine/threonine-protein kinase Chk2target
FostamatinibCitron Rho-interacting kinasetarget
FostamatinibDual specificity protein kinase CLK1target
FostamatinibDual specificity protein kinase CLK2target
FostamatinibDual specificity protein kinase CLK3target
FostamatinibDual specificity protein kinase CLK4target
FostamatinibMacrophage colony-stimulating factor 1 receptortarget
FostamatinibTyrosine-protein kinase CSKtarget
FostamatinibCasein kinase I isoform alphatarget
FostamatinibCasein kinase II subunit alphatarget
FostamatinibCasein kinase II subunit alpha'target
FostamatinibDeath-associated protein kinase 1target
FostamatinibDeath-associated protein kinase 2target
FostamatinibDeath-associated protein kinase 3target
FostamatinibSerine/threonine-protein kinase DCLK1target
FostamatinibSerine/threonine-protein kinase DCLK2target
FostamatinibSerine/threonine-protein kinase DCLK3target
FostamatinibEpithelial discoidin domain-containing receptor 1target
FostamatinibDiscoidin domain-containing receptor 2target
FostamatinibDual specificity tyrosine-phosphorylation-regulated kinase 1Atarget
FostamatinibDual specificity tyrosine-phosphorylation-regulated kinase 1Btarget
FostamatinibEpidermal growth factor receptortarget
FostamatinibEukaryotic translation initiation factor 2-alpha kinase 1target
FostamatinibInterferon-induced, double-stranded RNA-activated protein kinasetarget
FostamatinibeIF-2-alpha kinase GCN2target
FostamatinibEphrin type-A receptor 1target
FostamatinibEphrin type-A receptor 2target
FostamatinibEphrin type-A receptor 3target
FostamatinibEphrin type-A receptor 4target
FostamatinibEphrin type-A receptor 5target
FostamatinibEphrin type-A receptor 6target
FostamatinibEphrin type-A receptor 7target
FostamatinibEphrin type-A receptor 8target
FostamatinibEphrin type-B receptor 1target
FostamatinibEphrin type-B receptor 2target
FostamatinibEphrin type-B receptor 4target
FostamatinibEphrin type-B receptor 6target
FostamatinibReceptor tyrosine-protein kinase erbB-2target
FostamatinibReceptor tyrosine-protein kinase erbB-4target
FostamatinibSerine/threonine-protein kinase/endoribonuclease IRE1target
FostamatinibTyrosine-protein kinase Fertarget
FostamatinibTyrosine-protein kinase Fes/Fpstarget
FostamatinibFibroblast growth factor receptor 1target
FostamatinibFibroblast growth factor receptor 2target
FostamatinibFibroblast growth factor receptor 3target
FostamatinibTyrosine-protein kinase Fgrtarget
FostamatinibVascular endothelial growth factor receptor 1target
FostamatinibReceptor-type tyrosine-protein kinase FLT3target
FostamatinibVascular endothelial growth factor receptor 3target
FostamatinibSerine/threonine-protein kinase mTORtarget
FostamatinibTyrosine-protein kinase FRKtarget
FostamatinibTyrosine-protein kinase Fyntarget
FostamatinibCyclin-G-associated kinasetarget
FostamatinibGlycogen synthase kinase-3 alphatarget
FostamatinibGlycogen synthase kinase-3 betatarget
FostamatinibTyrosine-protein kinase HCKtarget
FostamatinibHomeodomain-interacting protein kinase 2target
FostamatinibHomeodomain-interacting protein kinase 3target
FostamatinibSerine/threonine-protein kinase ICKtarget
FostamatinibInhibitor of nuclear factor kappa-B kinase subunit betatarget
FostamatinibInhibitor of nuclear factor kappa-B kinase subunit epsilontarget
FostamatinibInsulin receptortarget
FostamatinibInsulin receptor-related proteintarget
FostamatinibInterleukin-1 receptor-associated kinase 1target
FostamatinibInterleukin-1 receptor-associated kinase 3target
FostamatinibInterleukin-1 receptor-associated kinase 4target
FostamatinibTyrosine-protein kinase ITK/TSKtarget
FostamatinibTyrosine-protein kinase JAK2target
FostamatinibTyrosine-protein kinase JAK3target
FostamatinibVascular endothelial growth factor receptor 2target
FostamatinibSerine/threonine-protein kinase SIK3target
FostamatinibMast/stem cell growth factor receptor Kittarget
FostamatinibSerine/threonine-protein kinase LATS1target
FostamatinibTyrosine-protein kinase Lcktarget
FostamatinibLIM domain kinase 1target
FostamatinibLIM domain kinase 2target
FostamatinibLeucine-rich repeat serine/threonine-protein kinase 2target
FostamatinibLeukocyte tyrosine kinase receptortarget
FostamatinibTyrosine-protein kinase Lyntarget
FostamatinibDual specificity mitogen-activated protein kinase kinase 2target
FostamatinibDual specificity mitogen-activated protein kinase kinase 3target
FostamatinibDual specificity mitogen-activated protein kinase kinase 5target
FostamatinibDual specificity mitogen-activated protein kinase kinase 6target
FostamatinibMitogen-activated protein kinase kinase kinase 1target
FostamatinibMitogen-activated protein kinase kinase kinase 10target
FostamatinibMitogen-activated protein kinase kinase kinase 11target
FostamatinibMitogen-activated protein kinase kinase kinase 12target
FostamatinibMitogen-activated protein kinase kinase kinase 13target
FostamatinibMitogen-activated protein kinase kinase kinase 15target
FostamatinibMitogen-activated protein kinase kinase kinase 2target
FostamatinibMitogen-activated protein kinase kinase kinase 3target
FostamatinibMitogen-activated protein kinase kinase kinase 4target
FostamatinibMitogen-activated protein kinase kinase kinase 6target
FostamatinibMitogen-activated protein kinase kinase kinase 9target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 1target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 2target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 3target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 4target
FostamatinibMitogen-activated protein kinase kinase kinase kinase 5target
FostamatinibMitogen-activated protein kinase 10target
FostamatinibMitogen-activated protein kinase 13target
FostamatinibMitogen-activated protein kinase 14target
FostamatinibMitogen-activated protein kinase 15target
FostamatinibMitogen-activated protein kinase 4target
FostamatinibMitogen-activated protein kinase 7target
FostamatinibMitogen-activated protein kinase 9target
FostamatinibMAP kinase-activated protein kinase 5target
FostamatinibSerine/threonine-protein kinase MARK1target
FostamatinibSerine/threonine-protein kinase MARK2target
FostamatinibMAP/microtubule affinity-regulating kinase 3target
FostamatinibMAP/microtubule affinity-regulating kinase 4target
FostamatinibCLIP-associating protein 1target
FostamatinibMicrotubule-associated serine/threonine-protein kinase 1target
FostamatinibMegakaryocyte-associated tyrosine-protein kinasetarget
FostamatinibMaternal embryonic leucine zipper kinasetarget
FostamatinibTyrosine-protein kinase Mertarget
FostamatinibMisshapen-like kinase 1target
FostamatinibMAP kinase-interacting serine/threonine-protein kinase 1target
FostamatinibMAP kinase-interacting serine/threonine-protein kinase 2target
FostamatinibMacrophage-stimulating protein receptortarget
FostamatinibMuscle, skeletal receptor tyrosine-protein kinasetarget
FostamatinibMyosin light chain kinase, smooth muscletarget
FostamatinibMyosin light chain kinase 2, skeletal/cardiac muscletarget
FostamatinibMyosin light chain kinase 3target
FostamatinibMyosin light chain kinase family member 4target
FostamatinibMyosin-IIIatarget
FostamatinibSerine/threonine-protein kinase Nek1target
FostamatinibSerine/threonine-protein kinase Nek11target
FostamatinibSerine/threonine-protein kinase Nek2target
FostamatinibSerine/threonine-protein kinase Nek3target
FostamatinibSerine/threonine-protein kinase Nek4target
FostamatinibSerine/threonine-protein kinase Nek5target
FostamatinibSerine/threonine-protein kinase Nek9target
FostamatinibHigh affinity nerve growth factor receptortarget
FostamatinibBDNF/NT-3 growth factors receptortarget
FostamatinibNT-3 growth factor receptortarget
FostamatinibNUAK family SNF1-like kinase 1target
FostamatinibNUAK family SNF1-like kinase 2target
FostamatinibSerine/threonine-protein kinase OSR1target
FostamatinibSerine/threonine-protein kinase PAK 1target
FostamatinibSerine/threonine-protein kinase PAK 2target
FostamatinibSerine/threonine-protein kinase PAK 3target
FostamatinibSerine/threonine-protein kinase PAK 4target
FostamatinibSerine/threonine-protein kinase PAK 6target
FostamatinibSerine/threonine-protein kinase PAK 5target
FostamatinibCyclin-dependent kinase 16target
FostamatinibCyclin-dependent kinase 17target
FostamatinibPlatelet-derived growth factor receptor alphatarget
FostamatinibPlatelet-derived growth factor receptor betatarget
Fostamatinib3-phosphoinositide-dependent protein kinase 1target
FostamatinibCyclin-dependent kinase 15target
FostamatinibPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoformtarget
FostamatinibPhosphatidylinositol 4-kinase betatarget
FostamatinibPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betatarget
FostamatinibPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gammatarget
FostamatinibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformtarget
FostamatinibPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoformtarget
FostamatinibSerine/threonine-protein kinase pim-1target
FostamatinibSerine/threonine-protein kinase pim-3target
FostamatinibPhosphatidylinositol 5-phosphate 4-kinase type-2 betatarget
FostamatinibPhosphatidylinositol 5-phosphate 4-kinase type-2 gammatarget
FostamatinibMembrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinasetarget
FostamatinibSerine/threonine-protein kinase N1target
FostamatinibSerine/threonine-protein kinase N2target
FostamatinibSerine/threonine-protein kinase PLK1target
FostamatinibSerine/threonine-protein kinase PLK2target
FostamatinibSerine/threonine-protein kinase PLK3target
FostamatinibSerine/threonine-protein kinase PLK4target
Fostamatinib5'-AMP-activated protein kinase catalytic subunit alpha-1target
Fostamatinib5'-AMP-activated protein kinasetarget
FostamatinibcAMP-dependent protein kinase catalytic subunit betatarget
FostamatinibProtein kinase C delta typetarget
FostamatinibProtein kinase C epsilon typetarget
FostamatinibProtein kinase C gamma type (PRKCG)target
FostamatinibProtein kinase C iota typetarget
FostamatinibProtein kinase C theta typetarget
FostamatinibSerine/threonine-protein kinase D1target
FostamatinibcGMP-dependent protein kinase 2target
FostamatinibSerine/threonine-protein kinase PRP4 homologtarget
FostamatinibFocal adhesion kinase 1target
FostamatinibProtein-tyrosine kinase 2-betatarget
FostamatinibProtein-tyrosine kinase 6target
FostamatinibRAF proto-oncogene serine/threonine-protein kinasetarget
FostamatinibProto-oncogene tyrosine-protein kinase receptor Rettarget
FostamatinibSerine/threonine-protein kinase RIO1target
FostamatinibSerine/threonine-protein kinase RIO2target
FostamatinibSerine/threonine-protein kinase RIO3target
FostamatinibReceptor-interacting serine/threonine-protein kinase 1target
FostamatinibReceptor-interacting serine/threonine-protein kinase 2target
FostamatinibReceptor-interacting serine/threonine-protein kinase 4target
FostamatinibRho-associated protein kinase 2target
FostamatinibProto-oncogene tyrosine-protein kinase ROStarget
FostamatinibRibosomal protein S6 kinase alpha-1target
FostamatinibRibosomal protein S6 kinase alpha-3target
FostamatinibSerine/threonine-protein kinase SBK1target
FostamatinibUncharacterized serine/threonine-protein kinase SBK3target
FostamatinibSerine/threonine-protein kinase Sgk3target
FostamatinibSerine/threonine-protein kinase SIK1target
FostamatinibSerine/threonine-protein kinase SIK2target
FostamatinibSTE20-like serine/threonine-protein kinasetarget
FostamatinibSNF-related serine/threonine-protein kinasetarget
FostamatinibProto-oncogene tyrosine-protein kinase Srctarget
FostamatinibTyrosine-protein kinase Srmstarget
FostamatinibSerine/threonine-protein kinase 10target
FostamatinibSerine/threonine-protein kinase 16target
FostamatinibSerine/threonine-protein kinase 17Atarget
FostamatinibSerine/threonine-protein kinase 17Btarget
FostamatinibSerine/threonine-protein kinase 32Atarget
FostamatinibCytochrome P450 3A4enzyme
FostamatinibATP-binding cassette sub-family G member 2transporter
FostamatinibATP-binding cassette sub-family B member 5transporter
FostamatinibUDP-glucuronosyltransferase 1-9enzyme
MilrinonecGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
IbudilastcGMP-inhibited 3',5'-cyclic phosphodiesterase Atarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
IbudilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DoxofyllinePhosphodiesterase 2A, cGMP-stimulatedtarget
DoxofyllineAdenosine receptor A2atarget
DoxofyllineBeta-2 adrenergic receptortarget
DoxofyllineCytochrome P450 1A2enzyme