Antimalarials

Agents used in the treatment of malaria. They are usually classified on the basis of their action against plasmodia at different stages in their life cycle in the human. (From AMA, Drug Evaluations Annual, 1992, p1585)
DrugDrug NameDrug Description
DB00205PyrimethamineAn antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria.
DB00358MefloquineAn antimalarial agent used as a schizonticidal agent.
DB00468QuinineAn alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
DB00613AmodiaquineFor treatment of acute malarial attacks in non-immune subjects.
DB01087PrimaquineAn antimalarial indicated to prevent relapse of vivax malaria.
DB01131ProguanilA medication indicated for prophylaxis and treatment of Plasmodium falciparum malaria.
DB01218HalofantrineAn antimalarial used for the treatment of severe malaria.
DB01611HydroxychloroquineAn antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.
DB06697ArtemetherAn antimalarial agent used in combination with lumefantrine for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.
DB06708LumefantrineAn antimalarial agent used in combination with artemether for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.
DB09274ArtesunateFor the treatment of severe malaria caused by Plasmodium falciparum in adults and children
DB11638ArtenimolFor the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB13941.
DB12975PyronaridinePyronaridine has been investigated for the treatment of Malaria.
DB13851ArtemotilArtemotil, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria...
DB01117AtovaquoneAn antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria.
DB13941PiperaquineFor the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB11638.
DB00908QuinidineA medication used to restore normal sinus rhythm, treat atrial fibrillation and flutter, and treat ventricular arrhythmias.
DB01103QuinacrineFor the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.
DB01299SulfadoxineA long acting sulfonamide used for the treatment or prevention of malaria.
DB06608TafenoquineAn antiparasitic agent used for the treatment and prevention of relapse of Vivax malaria.
DB12314ChlorproguanilChlorproguanil has been used in trials studying the treatment of MALARIA.
DB12617MizoribineMizoribine has been investigated for the treatment of Rheumatoid Arthritis.
DB13132ArtemisininArtemisinin has been used in trials studying the treatment of Schizophrenia, Malaria, Falciparum, and Plasmodium Falciparum.
DB00250DapsoneA sulfone drug used to treat acne vulgaris, Hansen's disease, and dermatitis herpetiformis.
DB00608ChloroquineAn antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis.
DB14066TetrandrineNot Annotated
DB12480Betulinic AcidBetulinic Acid has been used in trials studying the treatment of Dysplastic Nevus Syndrome.
DB14763CycloguanilCycloguanil is the active metabolite of proguanil.
DB11809ArtefenomelArtefenomel has been investigated for the treatment of Malaria.
DrugDrug NameTargetType
DB00205PyrimethamineBifunctional dihydrofolate reductase-thymidylate synthasetarget
DB00205PyrimethamineDihydrofolate reductasetarget
DB00205PyrimethamineCytochrome P450 2C8enzyme
DB00205PyrimethamineBeta-hexosaminidase subunit betatarget
DB00205PyrimethamineMultidrug and toxin extrusion protein 1transporter
DB00205PyrimethamineMultidrug and toxin extrusion protein 2transporter
DB00358MefloquineHemoglobin subunit alphatarget
DB00358MefloquineCholinesteraseenzyme
DB00358MefloquineCytochrome P450 3A4enzyme
DB00358MefloquineAdenosine receptor A2atarget
DB00358MefloquineFe(II)-protoporphyrin IXtarget
DB00358MefloquineP-glycoprotein 1transporter
DB00358MefloquineCytochrome P450 19A1enzyme
DB00358MefloquineAcetylcholinesteraseenzyme
DB00468QuininePlatelet glycoprotein IXtarget
DB00468QuinineIntermediate conductance calcium-activated potassium channel protein 4target
DB00468QuinineCytochrome P450 3A4enzyme
DB00468QuinineCytochrome P450 3A5enzyme
DB00468QuinineCytochrome P450 1A1enzyme
DB00468QuinineCytochrome P450 2D6enzyme
DB00468QuinineCytochrome P450 1A2enzyme
DB00468QuinineCytochrome P450 2C8enzyme
DB00468QuinineCytochrome P450 2C9enzyme
DB00468QuinineCytochrome P450 2C19enzyme
DB00468QuinineCytochrome P450 2E1enzyme
DB00468QuinineCytochrome P450 3A7enzyme
DB00468QuinineSolute carrier family 22 member 2transporter
DB00468QuinineSolute carrier family 22 member 1transporter
DB00468QuinineSolute carrier family 22 member 5transporter
DB00468QuinineP-glycoprotein 1transporter
DB00468QuinineSolute carrier organic anion transporter family member 1A2transporter
DB00468QuinineSolute carrier family 22 member 4transporter
DB00468QuinineFe(II)-protoporphyrin IXtarget
DB00468QuinineSolute carrier organic anion transporter family member 1B1transporter
DB00613AmodiaquineHistamine N-methyltransferasetarget
DB00613AmodiaquineCytochrome P450 2C8enzyme
DB00613AmodiaquineCytochrome P450 2D6enzyme
DB00613AmodiaquineFe(II)-protoporphyrin IXtarget
DB00613AmodiaquineCytochrome P450 1A1enzyme
DB00613AmodiaquineCytochrome P450 1B1enzyme
DB00613AmodiaquineCytochrome P450 2C9enzyme
DB00613AmodiaquineP-glycoprotein 1transporter
DB01087PrimaquineCytochrome P450 1A1enzyme
DB01087PrimaquineCytochrome P450 1A2enzyme
DB01087PrimaquineCytochrome P450 3A4enzyme
DB01087PrimaquineKeratin, type II cytoskeletal 7target
DB01087PrimaquineCytochrome P450 1B1enzyme
DB01087PrimaquineCytochrome P450 2D6enzyme
DB01087PrimaquineRibosyldihydronicotinamide dehydrogenase [quinone]target
DB01087PrimaquineFe(II)-protoporphyrin IXtarget
DB01087PrimaquineP-glycoprotein 1transporter
DB01131ProguanilBifunctional dihydrofolate reductase-thymidylate synthasetarget
DB01131ProguanilDihydrofolate reductasetarget
DB01131ProguanilCytochrome P450 2C19enzyme
DB01131ProguanilCytochrome P450 2D6enzyme
DB01131ProguanilCytochrome P450 2C9enzyme
DB01218HalofantrineFe(II)-protoporphyrin IXtarget
DB01218HalofantrinePotassium voltage-gated channel subfamily H member 2target
DB01218HalofantrineCytochrome P450 3A4enzyme
DB01218HalofantrineCytochrome P450 2D6enzyme
DB01218HalofantrinePlasmepsin-2target
DB01218HalofantrineCytochrome P450 2C8enzyme
DB01218HalofantrineCytochrome P450 3A5enzyme
DB01611HydroxychloroquineDNAtarget
DB01611HydroxychloroquineToll-like receptor 7target
DB01611HydroxychloroquineToll-like receptor 9target
DB01611HydroxychloroquineCytochrome P450 2D6enzyme
DB01611HydroxychloroquineP-glycoprotein 1transporter
DB01611HydroxychloroquineSerum albumincarrier
DB01611Hydroxychloroquinealpha1-acid glycoproteincarrier
DB01611HydroxychloroquineCytochrome P450 3A4enzyme
DB01611HydroxychloroquineSolute carrier organic anion transporter family member 1A2transporter
DB06697ArtemetherCytochrome P450 3A4enzyme
DB06697ArtemetherCytochrome P450 3A5enzyme
DB06697ArtemetherCytochrome P450 2B6enzyme
DB06697ArtemetherCytochrome P450 2C9enzyme
DB06697ArtemetherCytochrome P450 2C19enzyme
DB06708LumefantrineCytochrome P450 2D6enzyme
DB06708LumefantrineCytochrome P450 3A4enzyme
DB09274ArtesunateMalaria protein EXP-1target
DB09274ArtesunateCytochrome P450 2A6enzyme
DB09274ArtesunateCytochrome P450 3A4enzyme
DB11638ArtenimolActin, cytoplasmic 2target
DB11638ArtenimolAlpha-aminoadipic semialdehyde dehydrogenasetarget
DB11638ArtenimolAnnexin A2target
DB11638ArtenimolATP synthase subunit alpha, mitochondrialtarget
DB11638ArtenimolATP synthase subunit g, mitochondrialtarget
DB11638ArtenimolATP synthase subunit O, mitochondrialtarget
DB11638ArtenimolCalpastatintarget
DB11638ArtenimolT-complex protein 1 subunit gammatarget
DB11638ArtenimolCofilin-1target
DB11638ArtenimolChloride intracellular channel protein 1target
DB11638ArtenimolCysteine and glycine-rich protein 1target
DB11638ArtenimolDihydropyrimidinase-related protein 2target
DB11638ArtenimolDesmoplakintarget
DB11638ArtenimolElongation factor 1-alpha 1target
DB11638ArtenimolAlpha-enolasetarget
DB11638ArtenimolFilamin-Atarget
DB11638ArtenimolAlpha-ketoglutarate-dependent dioxygenase FTOtarget
DB11638ArtenimolGlucose-6-phosphate 1-dehydrogenasetarget
DB11638ArtenimolGlyceraldehyde-3-phosphate dehydrogenase, testis-specifictarget
DB11638ArtenimolGlucose-6-phosphate isomerasetarget
DB11638ArtenimolHeterogeneous nuclear ribonucleoproteins A2/B1target
DB11638ArtenimolHeterogeneous nuclear ribonucleoprotein D0target
DB11638ArtenimolHeterogeneous nuclear ribonucleoprotein Ktarget
DB11638ArtenimolHeterochromatin protein 1-binding protein 3target
DB11638ArtenimolHeat shock protein beta-1target
DB11638ArtenimolRas GTPase-activating-like protein IQGAP1target
DB11638ArtenimolFar upstream element-binding protein 2target
DB11638ArtenimolL-lactate dehydrogenase A chaintarget
DB11638ArtenimolL-lactate dehydrogenase B chaintarget
DB11638ArtenimolGalectin-1target
DB11638ArtenimolMicrotubule-associated protein 4target
DB11638ArtenimolMalate dehydrogenase, cytoplasmictarget
DB11638ArtenimolPuromycin-sensitive aminopeptidasetarget
DB11638ArtenimolProfilin-1target
DB11638ArtenimolPhosphoglycerate kinase 1target
DB11638ArtenimolPyruvate kinase PKMtarget
DB11638ArtenimolPeptidyl-prolyl cis-trans isomerase Atarget
DB11638ArtenimolPeroxiredoxin-1target
DB11638Artenimol60S ribosomal protein L10target
DB11638Artenimol60S ribosomal protein L14target
DB11638Artenimol60S ribosomal protein L18target
DB11638Artenimol60S ribosomal protein L23atarget
DB11638Artenimol60S ribosomal protein L35target
DB11638Artenimol60S ribosomal protein L4target
DB11638Artenimol40S ribosomal protein S13target
DB11638Artenimol40S ribosomal protein S17target
DB11638Artenimol40S ribosomal protein S18target
DB11638Artenimol40S ribosomal protein S19target
DB11638Artenimol40S ribosomal protein S28target
DB11638Artenimol40S ribosomal protein S5target
DB11638Artenimol40S ribosomal protein S6target
DB11638Artenimol40S ribosomal protein S8target
DB11638Artenimol40S ribosomal protein S9target
DB11638ArtenimolSplicing factor 1target
DB11638ArtenimolSplicing factor, proline- and glutamine-richtarget
DB11638ArtenimolSmall nuclear ribonucleoprotein Sm D2target
DB11638ArtenimolSignal recognition particle 14 kDa proteintarget
DB11638ArtenimolSerine/arginine-rich splicing factor 4target
DB11638ArtenimolTransgelintarget
DB11638ArtenimolTransgelin-2target
DB11638ArtenimolTriosephosphate isomerasetarget
DB11638ArtenimolTropomyosin alpha-1 chaintarget
DB11638ArtenimolTubulin alpha-1A chaintarget
DB11638ArtenimolVimentintarget
DB11638ArtenimolZyxintarget
DB11638ArtenimolHeat shock cognate 71 kDa proteintarget
DB11638ArtenimolTubulin beta-6 chaintarget
DB11638ArtenimolTubulin beta-4A chaintarget
DB11638ArtenimolTubulin beta chaintarget
DB11638ArtenimolFructose-bisphosphate aldolase Atarget
DB11638ArtenimolGlyceraldehyde-3-phosphate dehydrogenasetarget
DB11638ArtenimolCytochrome ctarget
DB11638ArtenimolPhosphoglycerate mutase 1target
DB11638ArtenimolMyosin-9target
DB11638ArtenimolProtein disulfide-isomerasetarget
DB11638ArtenimolProbable ATP-dependent RNA helicase DDX5target
DB11638ArtenimolSerine hydroxymethyltransferase, mitochondrialtarget
DB11638ArtenimolSpliceosome RNA helicase DDX39Btarget
DB11638ArtenimolNucleophosmintarget
DB11638ArtenimolTranslationally-controlled tumor protein homologtarget
DB11638ArtenimolP-type Ca2+-transporting ATPasetarget
DB11638ArtenimolOrnithine aminotransferasetarget
DB11638ArtenimolElongation factor 1-alphatarget
DB11638ArtenimolMultidrug resistance proteintarget
DB11638ArtenimolElongation factor 2target
DB11638ArtenimolActin-1target
DB11638ArtenimolGlyceraldehyde-3-phosphate dehydrogenasetarget
DB11638ArtenimolFructose-bisphosphate aldolasetarget
DB11638ArtenimolCell division cycle protein 48 homologue,putativetarget
DB11638ArtenimolHeat shock protein 90target
DB11638ArtenimolEukaryotic initiation factor 4Atarget
DB11638ArtenimolPyruvate kinasetarget
DB11638ArtenimolL-lactate dehydrogenasetarget
DB11638ArtenimolProtein disulfide-isomerasetarget
DB11638ArtenimolThioredoxin-related protein, putativetarget
DB11638ArtenimolSpermidine synthasetarget
DB11638ArtenimolProbable ATP-dependent 6-phosphofructokinasetarget
DB11638ArtenimolGlutamate dehydrogenasetarget
DB11638ArtenimolEndoplasmin homolog, putativetarget
DB11638ArtenimolHypoxanthine-guanine-xanthine phosphoribosyltransferasetarget
DB11638ArtenimolEnolasetarget
DB11638Artenimol40S ribosomal protein S3target
DB11638ArtenimolNon-SERCA-type Ca2+-transporting P-ATPasetarget
DB11638ArtenimolTubulin alpha chaintarget
DB11638ArtenimolKnob-associated histidine-rich proteintarget
DB11638ArtenimolS-adenosylmethionine synthasetarget
DB11638ArtenimolV-type H(+)-translocating pyrophosphatase, putativetarget
DB11638Artenimol60S ribosomal protein L4target
DB11638ArtenimolPhosphoethanolamine N-methyltransferasetarget
DB11638Artenimol40S ribosomal protein S3atarget
DB11638ArtenimolConserved Plasmodium membrane proteintarget
DB11638Artenimol60S ribosomal protein L3target
DB11638ArtenimolHigh molecular weight rhoptry protein 2target
DB11638ArtenimolSerine repeat antigen 5target
DB11638Artenimol40S ribosomal protein S19target
DB11638ArtenimolGlycophorin-binding proteintarget
DB11638ArtenimolCalcium-transporting ATPasetarget
DB11638ArtenimolV-type proton ATPase catalytic subunit Atarget
DB11638Artenimol60S ribosomal protein L2target
DB11638ArtenimolAcyl-CoA synthetasetarget
DB11638ArtenimolPlasmepsin IVtarget
DB11638ArtenimolPlasmepsin-1target
DB11638ArtenimolChloroquine resistance transportertarget
DB11638Artenimol14-3-3 proteintarget
DB11638ArtenimolIsoleucine--tRNA ligase, putativetarget
DB11638ArtenimolPlasmodium exported proteintarget
DB11638ArtenimolTubulin beta chaintarget
DB11638Artenimol60S ribosomal protein L27target
DB11638ArtenimolSec62, putativetarget
DB11638ArtenimolAutophagy-related protein 18, putativetarget
DB11638ArtenimolMature parasite-infected erythrocyte surface antigentarget
DB11638ArtenimolImportin-7, putativetarget
DB11638ArtenimolImportin subunit alphatarget
DB11638ArtenimolPeptidyl-prolyl cis-trans isomerasetarget
DB11638ArtenimolDnaJ protein, putativetarget
DB11638ArtenimolMerozoite surface protein 1target
DB11638ArtenimolGlutamate--tRNA ligasetarget
DB11638ArtenimolT-complex protein 1 subunit etatarget
DB11638ArtenimolPlasmepsin-2target
DB11638ArtenimolChaperone, putativetarget
DB11638ArtenimolRhoptry neck protein 3target
DB11638Artenimol40S ribosomal protein S5, putativetarget
DB11638ArtenimolSkeleton-binding protein 1target
DB11638ArtenimolPurine nucleotide phosphorylase, putativetarget
DB11638ArtenimolAdenosylhomocysteinasetarget
DB11638ArtenimolAdenosine deaminasetarget
DB11638ArtenimolMethionine--tRNA ligasetarget
DB11638ArtenimolCarbamoyl phosphate synthetasetarget
DB11638ArtenimolAspartate carbamoyltransferasetarget
DB11638ArtenimolSignal recognition particle receptor, beta subunittarget
DB11638ArtenimolParasite-infected erythrocyte surface proteintarget
DB11638ArtenimolCoatomer alpha subunit, putativetarget
DB11638ArtenimolHexokinasetarget
DB11638ArtenimolProteasome subunit alpha typetarget
DB11638ArtenimolHaloacid dehalogenase-like hydrolasetarget
DB11638ArtenimolInsulinase, putativetarget
DB11638Artenimol40S ribosomal protein S21target
DB11638ArtenimolUbiquitin-conjugating enzyme E2target
DB11638ArtenimolEukaryotic translation initiation factor 3 subunit Ctarget
DB11638Artenimol60S ribosomal protein L24, putativetarget
DB11638Artenimol60S ribosomal protein L23target
DB11638Artenimol60S ribosomal protein L17, putativetarget
DB11638ArtenimolHAP proteintarget
DB11638ArtenimolHeat shock protein 110, putativetarget
DB11638Artenimol60S ribosomal protein L10, putativetarget
DB11638ArtenimolLysophospholipase, putativetarget
DB11638ArtenimolPolyadenylate-binding proteintarget
DB11638ArtenimolUbiquitin-60S ribosomal protein L40target
DB11638ArtenimolPhosphoribosylpyrophosphate synthetasetarget
DB11638ArtenimolThioredoxin peroxidase 1target
DB11638ArtenimolProtein transport protein SEC31target
DB11638ArtenimolDipeptidyl aminopeptidase 1target
DB11638ArtenimolRing-infected erythrocyte surface antigentarget
DB11638ArtenimolATP-dependent RNA helicase UAP56target
DB11638ArtenimolCalcium-dependent protein kinase 4target
DB11638ArtenimolGTP-binding nuclear protein Rantarget
DB11638ArtenimolNucleoside transporter 2target
DB11638ArtenimolAnamorsin homologtarget
DB11638ArtenimolGlutamine synthetase, putativetarget
DB11638Artenimol60S ribosomal protein L30e, putativetarget
DB11638ArtenimolCasein kinase 2, alpha subunittarget
DB11638ArtenimolThreonine--tRNA ligasetarget
DB11638ArtenimolcAMP-dependent protein kinase regulatory subunittarget
DB11638ArtenimolElongation factor 1-gamma, putativetarget
DB11638ArtenimolThioredoxin-like proteintarget
DB11638Artenimol60S ribosomal protein L21target
DB11638Artenimol60S ribosomal protein L14, putativetarget
DB11638ArtenimolInner membrane complex sub-compartment protein 3target
DB11638ArtenimolHSP40, subfamily A, putativetarget
DB11638ArtenimolPyridoxal 5'-phosphate synthase subunit Pdx1target
DB11638ArtenimolUDP-glucuronosyltransferase 1-9enzyme
DB11638ArtenimolUDP-glucuronosyltransferase 2B7enzyme
DB11638ArtenimolSerum albumintarget
DB11638ArtenimolCytochrome P450 2D6enzyme
DB11638ArtenimolCytochrome P450 2C19enzyme
DB01117AtovaquoneDihydroorotate dehydrogenase (quinone), mitochondrialtarget
DB01117AtovaquoneDihydroorotate dehydrogenase (quinone), mitochondrialtarget
DB01117AtovaquoneCytochrome btarget
DB01117AtovaquoneCytochrome P450 2C9enzyme
DB01117AtovaquoneCytochrome P450 3A4enzyme
DB01117AtovaquoneP-glycoprotein 1transporter
DB13941PiperaquineCytochrome P450 3A4enzyme
DB13941PiperaquineCytochrome P450 2C19enzyme
DB13941PiperaquineCytochrome P450 2C9enzyme
DB13941PiperaquineCytochrome P450 2B6enzyme
DB13941PiperaquineCytochrome P450 2E1enzyme
DB00908QuinidineSodium channel protein type 5 subunit alphatarget
DB00908QuinidineAlpha-1-acid glycoprotein 1carrier
DB00908QuinidinePotassium voltage-gated channel subfamily H member 2target
DB00908QuinidinePotassium channel subfamily K member 1target
DB00908QuinidinePotassium channel subfamily K member 6target
DB00908QuinidineCytochrome P450 1A2enzyme
DB00908QuinidineCytochrome P450 2E1enzyme
DB00908QuinidineCytochrome P450 1A1enzyme
DB00908QuinidineCytochrome P450 2D6enzyme
DB00908QuinidineCytochrome P450 3A4enzyme
DB00908QuinidineCytochrome P450 3A7enzyme
DB00908QuinidineSolute carrier family 22 member 2transporter
DB00908QuinidineSolute carrier family 22 member 1transporter
DB00908QuinidineSolute carrier family 22 member 5transporter
DB00908QuinidineP-glycoprotein 1transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1A2transporter
DB00908QuinidineSolute carrier family 22 member 8transporter
DB00908QuinidineCanalicular multispecific organic anion transporter 1transporter
DB00908QuinidineSolute carrier family 22 member 4transporter
DB00908QuinidineSolute carrier organic anion transporter family member 1B1transporter
DB00908QuinidineCytochrome P450 2B6enzyme
DB00908QuinidineCytochrome P450 2C9enzyme
DB00908QuinidineAlpha-1A adrenergic receptortarget
DB00908QuinidineAlpha-1B adrenergic receptortarget
DB00908QuinidineAlpha-1D adrenergic receptortarget
DB00908QuinidineBile salt export pumptransporter
DB00908QuinidineCytochrome P450 2C8enzyme
DB01103QuinacrineDNAtarget
DB01103Quinacrine85/88 kDa calcium-independent phospholipase A2target
DB01103QuinacrineCytosolic phospholipase A2target
DB01103QuinacrineInactive phospholipase C-like protein 1target
DB01103QuinacrineHistamine N-methyltransferaseenzyme
DB01103QuinacrineSolute carrier family 22 member 2transporter
DB01103QuinacrineP-glycoprotein 1transporter
DB01103QuinacrineCytochrome P450 3A4enzyme
DB01103QuinacrineCytochrome P450 3A5enzyme
DB01299SulfadoxineDihydropteroate synthetasetarget
DB01299SulfadoxineBifunctional dihydrofolate reductase-thymidylate synthasetarget
DB06608TafenoquineCytochrome P450 2D6enzyme
DB06608TafenoquineFerredoxin--NADP reductase, apicoplastenzyme
DB06608TafenoquineSolute carrier family 22 member 2transporter
DB06608TafenoquineMultidrug and toxin extrusion protein 1transporter
DB06608TafenoquineMultidrug and toxin extrusion protein 2transporter
DB13132ArtemisininCytochrome P450 2B6enzyme
DB00250DapsoneInactive dihydropteroate synthase 2target
DB00250DapsoneDihydropteroate synthase 1target
DB00250DapsoneCytochrome P450 2C9enzyme
DB00250DapsoneCytochrome P450 2E1enzyme
DB00250DapsoneCytochrome P450 3A4enzyme
DB00250DapsoneDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00250DapsoneProstaglandin G/H synthase 1enzyme
DB00250DapsoneProstaglandin G/H synthase 2enzyme
DB00250DapsoneCytochrome P450 2C8enzyme
DB00250DapsoneCytochrome P450 2C19enzyme
DB00250DapsoneArylamine N-acetyltransferase 2enzyme
DB00250DapsoneCytochrome P450 3A5enzyme
DB00250DapsoneCytochrome P450 3A7enzyme
DB00250DapsoneMyeloperoxidaseenzyme
DB00250DapsoneCytochrome P450 2C18enzyme
DB00608ChloroquineTumor necrosis factortarget
DB00608ChloroquineToll-like receptor 9target
DB00608ChloroquineGlutathione S-transferase A2target
DB00608ChloroquineCytochrome P450 2D6enzyme
DB00608ChloroquineCytochrome P450 3A4enzyme
DB00608ChloroquineCytochrome P450 1A1enzyme
DB00608ChloroquineCytochrome P450 2C8enzyme
DB00608ChloroquineCytochrome P450 3A5enzyme
DB00608ChloroquineFe(II)-protoporphyrin IXtarget
DB00608ChloroquineGlutathione S-transferasetarget
DB00608ChloroquineP-glycoprotein 1transporter
DB14066TetrandrineP-glycoprotein 1target
DB14066TetrandrineCytochrome P450 3A4enzyme