Hydroxybenzoates

Name
Hydroxybenzoates
Accession Number
DBCAT000580
Description

Benzoate derivatives substituted by one or more hydroxy groups in any position on the benzene ring.

Drugs
DrugDrug Description
Aminosalicylic acidAn aminosalicylate drug used to induce remission in ulcerative colitis.
BacitracinA cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections.
ProparacaineA topical anesthetic used for ophthalmic practice.
DiflunisalAn NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis.
Salicylic acidAn acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
BalsalazideAn aminosalicylate used to treat ulcerative colitis.
MetoclopramideAn antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.
OlsalazineAn anti-inflammatory agent used in the treatment of inflammatory bowel disease and ulcerative colitis.
Bismuth subsalicylateAn antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
Magnesium salicylateAn NSAID analgesic used in the symptomatic relief of mild to moderate muscular pain.
SalsalateA nonsteroidal anti-inflammatory agent used in the symptomatic relief of rheumatoid arthritis, osteoarthritis and related rheumatic disorders.
Choline magnesium trisalicylateCholine magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.
P-Anisic AcidNot Available
3-hydroxyanthranilic acidAn oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
DersalazineInvestigated for use/treatment in inflammatory bowel disease.
Phenyl aminosalicylateNot Annotated
TriflusalTriflusal is indicated as prophylaxis of thromboembolic disorders. It has been registered in Spain and in other countries of Europe, South America and South Korea for the prevention of Stroke...
BromoprideBromopride in indicated in the treatment of nausea and vomiting, including PONV (post-operative nausea and vomiting), gastroesophageal reflux disease (GERD/GORD), as well as endoscopy preparation and radiographic studies of the...
TrimebutineA spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery.
PropoxycainePropoxycaine is a local anesthetic medication. It was used beginning in the 1950s during dental procedures . It has been combined with procaine to accelerate its onset of action and...
Methyl salicylateA topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons.
OctisalateIngredient in sunscreens for protection against damage effects of sun light, provides protection from sunburns, aging and skin cancer.
HomosalateAs ingredient in many sunscreen for protection against sunburn, skin aging and skin cancer.
Phenyl salicylatePain and fever .
Trolamine salicylateA medication used to relieve minor aches and pains of the muscles and joints.
Glycol salicylateA salicylate used to treat mild to moderate muscle pain.
NonivamideNonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , .
NitroaspirinNitroaspirin has been investigated for the treatment of Intermittent Claudication.
Propyl GallatePropyl Gallate is under investigation in clinical trial NCT01450098 (A Study of LY2484595 in Healthy Subjects).
SalirasibSalirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.
HexobendineHexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris. It has not been approved in the United States or the United Kingdom, but has...
AloxiprinNot Annotated
GuacetisalNot Annotated
Carbaspirin calciumNot Annotated
Ethyl hydroxybenzoateNot Annotated
BenorilateNot Annotated
Imidazole salicylateNot Annotated
Hemoglobin crosfumarilHemoglobin in which the alpha-subunit are cross-linked intramolecularly.
Bismuth subgallateA medication used to deodorize flatulence and stools as well as hemostasis in soft tissue surgery.
Choline salicylateThe oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due...
Thiosalicylic acidNot Annotated
ButylparabenNot Annotated
BenzylparabenBenzylparaben is used in allergenic testing.
PropylparabenPropylparaben is used in allergenic testing.
MethylparabenMethylparaben is used in allergenic testing.
Vanillic acidA flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13).
MesalazineAn aminosalicylate drug used to treat mild to moderate active ulcerative colitis and also to maintain remission once achieved.
Methyl vanillateNot Available
p-Hydroxymercuribenzoic acidNot Available
Ethyl salicylateNot Annotated
4-hydroxybenzoic acidNot Available
Drugs & Drug Targets
DrugTargetType
Aminosalicylic acidGroup IIE secretory phospholipase A2target
Aminosalicylic acidProstaglandin G/H synthase 2target
Aminosalicylic acidArachidonate 5-lipoxygenasetarget
Aminosalicylic acidInhibitor of nuclear factor kappa-B kinase subunit alphatarget
Aminosalicylic acidMyeloperoxidaseenzyme
BacitracinAlpha-2-macroglobulintarget
BacitracinInsulin-degrading enzymetarget
BacitracinC55-isoprenyl pyrophosphatetarget
BacitracinBacitracin transport ATP-binding protein BcrAtransporter
BacitracinBacitracin transport permease protein BCRBtransporter
BacitracinBacitracin transport permease protein BcrCtransporter
ProparacaineSodium channel protein type 10 subunit alphatarget
DiflunisalProstaglandin G/H synthase 1target
DiflunisalProstaglandin G/H synthase 2target
DiflunisalTransthyretincarrier
DiflunisalSerum albumincarrier
DiflunisalSolute carrier family 22 member 6transporter
DiflunisalUDP-glucuronosyltransferase 1-8enzyme
DiflunisalUDP-glucuronosyltransferase 1-9enzyme
Salicylic acidSerum albumincarrier
Salicylic acidProstaglandin G/H synthase 1target
Salicylic acidProstaglandin G/H synthase 2target
Salicylic acidAldo-keto reductase family 1 member C1target
Salicylic acidSolute carrier family 22 member 6transporter
Salicylic acidSolute carrier family 22 member 10transporter
Salicylic acidSolute carrier family 22 member 8transporter
Salicylic acidSolute carrier family 22 member 11transporter
Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
Salicylic acidMonocarboxylate transporter 1transporter
Salicylic acidSolute carrier family 22 member 7transporter
Salicylic acidCytochrome P450 2C9enzyme
Acetylsalicylic acidProstaglandin G/H synthase 1target
Acetylsalicylic acidProstaglandin G/H synthase 2target
Acetylsalicylic acidAldo-keto reductase family 1 member C1target
Acetylsalicylic acidSolute carrier family 22 member 6transporter
Acetylsalicylic acidP-glycoprotein 1transporter
Acetylsalicylic acidCytochrome P450 2C19enzyme
Acetylsalicylic acidCytochrome P450 2C9enzyme
Acetylsalicylic acid5'-AMP-activated protein kinasetarget
Acetylsalicylic acidEndothelin-1 receptortarget
Acetylsalicylic acidCellular tumor antigen p53target
Acetylsalicylic acid78 kDa glucose-regulated proteintarget
Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
Acetylsalicylic acidCaspase-1target
Acetylsalicylic acidCaspase-3target
Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
Acetylsalicylic acidG1/S-specific cyclin-D1target
Acetylsalicylic acidMyc proto-oncogene proteintarget
Acetylsalicylic acidProliferating cell nuclear antigentarget
Acetylsalicylic acidCyclin Atarget
Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
Acetylsalicylic acidSolute carrier family 22 member 8transporter
BalsalazideProstaglandin G/H synthase 1target
BalsalazideProstaglandin G/H synthase 2target
BalsalazideArachidonate 5-lipoxygenasetarget
BalsalazidePeroxisome proliferator-activated receptor gammatarget
BalsalazideNADPH azoreductaseenzyme
MetoclopramideMuscarinic acetylcholine receptor M1target
MetoclopramideDopamine D2 receptortarget
MetoclopramideCytochrome P450 2D6enzyme
Metoclopramide5-hydroxytryptamine receptor 4target
Metoclopramide5-hydroxytryptamine receptor 3Atarget
MetoclopramideCytochrome P450 3A4enzyme
MetoclopramideCytochrome P450 1A2enzyme
MetoclopramideP-glycoprotein 1transporter
MetoclopramideAlpha-1-acid glycoprotein 1carrier
OlsalazineInterferon gammatarget
OlsalazineThiopurine S-methyltransferasetarget
Bismuth subsalicylateSerum albumincarrier
Bismuth subsalicylateSerotransferrincarrier
Magnesium salicylateSerum albumincarrier
Magnesium salicylateProstaglandin G/H synthase 1target
Magnesium salicylateProstaglandin G/H synthase 2target
SalsalateProstaglandin G/H synthase 1target
SalsalateProstaglandin G/H synthase 2target
Choline magnesium trisalicylateProstaglandin G/H synthase 1target
Choline magnesium trisalicylateProstaglandin G/H synthase 2target
P-Anisic AcidGroup IIE secretory phospholipase A2target
P-Anisic AcidPhospholipase A2target
3-hydroxyanthranilic acidTrans-2,3-dihydro-3-hydroxyanthranilate isomerasetarget
TriflusalProstaglandin G/H synthase 1target
TriflusalNuclear factor NF-kappa-B p105 subunittarget
TriflusalNitric oxide synthase, inducibletarget
TriflusalcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
TriflusalSerum albumincarrier
BromoprideDopamine D2 receptortarget
TrimebutineMu-type opioid receptortarget
TrimebutineVoltage-dependent L-type calcium channeltarget
TrimebutineCalcium-activated potassium channeltarget
TrimebutineVoltage-dependent T-type calcium channeltarget
TrimebutineMuscarinic acetylcholine receptor M1target
TrimebutineMuscarinic acetylcholine receptor M2target
TrimebutineMuscarinic acetylcholine receptor M3target
TrimebutineMuscarinic acetylcholine receptor M4target
TrimebutineCytochrome P450 3A4enzyme
PropoxycaineLiver carboxylesterase 1enzyme
PropoxycaineVoltage-gated sodium channel alpha subunittarget
HomosalateProgesterone receptortarget
HomosalateAndrogen receptortarget
HomosalateEstrogen receptor alphatarget
Phenyl salicylateProstaglandin G/H synthase 1target
Phenyl salicylateProstaglandin G/H synthase 2target
Trolamine salicylateProstaglandin G/H synthase 1target
Trolamine salicylateProstaglandin G/H synthase 2target
Glycol salicylateProstaglandin G/H synthase 1target
Glycol salicylateProstaglandin G/H synthase 2target
NonivamideTransient receptor potential cation channel subfamily V member 1target
NitroaspirinProstaglandin G/H synthase 1target
Propyl GallateEstrogen receptor alphatarget
Bismuth subgallateSerum albumincarrier
Choline salicylateCholine-phosphate cytidylyltransferase Btarget
Choline salicylateAcetylcholinesterasetarget
Choline salicylateCholine-phosphate cytidylyltransferase Atarget
Choline salicylatePhospholipase D2target
Choline salicylateCholinesterasetarget
Choline salicylatePhospholipase D1target
Choline salicylateSolute carrier family 22 member 2transporter
Choline salicylateSolute carrier family 22 member 1transporter
Choline salicylateSolute carrier family 22 member 3transporter
Choline salicylateSolute carrier family 22 member 5transporter
Choline salicylateSolute carrier family 22 member 4transporter
Choline salicylateCholine/ethanolaminephosphotransferase 1enzyme
Choline salicylateCholine transporter-like protein 1transporter
Choline salicylateCholine transporter-like protein 4transporter
Choline salicylateCholine transporter-like protein 3transporter
Choline salicylateCholine/ethanolamine kinaseenzyme
Choline salicylateCholine O-acetyltransferaseenzyme
Choline salicylateCholine kinase alphaenzyme
Choline salicylateCholine dehydrogenase, mitochondrialenzyme
Choline salicylateHigh affinity choline transporter 1transporter
Choline salicylateNeuronal acetylcholine receptor subunit alpha-7target
Vanillic acidChorismate--pyruvate lyasetarget
MesalazineProstaglandin G/H synthase 1target
MesalazineProstaglandin G/H synthase 2target
MesalazinePeroxisome proliferator-activated receptor gammatarget
MesalazineInhibitor of nuclear factor kappa-B kinase subunit alphatarget
MesalazineInhibitor of nuclear factor kappa-B kinase subunit betatarget
MesalazineArachidonate 5-lipoxygenasetarget
MesalazineMyeloperoxidasetarget
MesalazineArylamine N-acetyltransferasetarget
MesalazineArylamine N-acetyltransferase 1enzyme
Methyl vanillateEndo-1,4-beta-xylanase Ytarget
p-Hydroxymercuribenzoic acidCarbonic anhydrase 2target
4-hydroxybenzoic acidp-hydroxybenzoate hydroxylasetarget
4-hydroxybenzoic acidChorismate--pyruvate lyasetarget
4-hydroxybenzoic acidp-hydroxybenzoate hydroxylasetarget
4-hydroxybenzoic acid4-hydroxybenzoyl-CoA thioesterasetarget