- Hydroxy Acids
- Accession Number
Organic compounds containing both the hydroxyl and carboxyl radicals.
Drug Drug Description Ascorbic acid A vitamin used to correct vitamin C deficiency and to increase the intestinal absorption of iron. Trospium An antimuscarinic agent used to treat the symptoms of overactive bladder (OAB). Aminosalicylic acid An aminosalicylate drug used to induce remission in ulcerative colitis. Calcium glucoheptonate A calcium supplement combined with calcium gluconate to treat hypocalcemia and maintain calcium levels. Acetohydroxamic acid A synthetic urea derivative used to treat urea splitting bacterial infections of the urinary tract. Zanamivir A neuraminidase inhibitor used to treat influenza A and B. Bacitracin A cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections. Deferoxamine A chelating agent used to treat iron or aluminum toxicity and some blood transfusion dependent anemias. Clidinium A synthetic anticholinergic used to treat peptic ulcer disease, colicky abdominal pain, diverticulitis, and IBS. Marimastat For the treatment of various cancers Proparacaine A topical anesthetic used for ophthalmic practice. Diflunisal An NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis. Etacrynic acid A diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease. Salicylic acid An acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts. Balsalazide An aminosalicylate used to treat ulcerative colitis. Oxybutynin An antimuscarinic agent that reduces detrusor muscle activity, relaxing the bladder and preventing the urge to void. Rabeprazole A proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome. Trimetrexate A folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin. Olsalazine An anti-inflammatory agent used in the treatment of inflammatory bowel disease and ulcerative colitis. Bismuth subsalicylate An antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract. Magnesium salicylate An NSAID analgesic used in the symptomatic relief of mild to moderate muscular pain. Salsalate A nonsteroidal anti-inflammatory agent used in the symptomatic relief of rheumatoid arthritis, osteoarthritis and related rheumatic disorders. Choline magnesium trisalicylate Choline magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults. gamma-Hydroxybutyric acid Used as a general anesthetic, to treat conditions such as insomnia, clinical depression, narcolepsy, and alcoholism, and to improve athletic performance. Dimenoxadol Dimenoxadol is an opioid analgesic which produces typical opioid effects such as analgesia and sedation. It is structurally similar to methadone and is a benzilic acid derivative. In the United... SC-74020 Not Available Coprogen Not Available Phosphoenolpyruvate Not Available Benzhydroxamic Acid Not Available WAY-151693 Not Available 6-phospho-D-gluconic acid Not Available Benzoylformic Acid Not Available Vorinostat A histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies. P-Anisic Acid Not Available 2,4-Dihydroxybenzoic Acid Not Available Glycolic acid Not Available Gallichrome Not Available 2-Keto-3-Deoxygluconate Not Available 3-hydroxyanthranilic acid An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen. Xylarohydroxamate Not Available 3-Dehydroquinic Acid Not Available 3,4-Dihydroxybenzoic Acid Not Available Balanol Not Available Shikimate-3-Phosphate Not Available 3-Dehydroshikimate Not Available Bb-3497 Not Available Lactic acid An emollient and keratolytic used agent in various cosmetic products and used as an additive in various pharmaceutical products for its antibacterial properties. 4-Phospho-D-erythronohydroxamic acid Not Available Gluconolactone A polyhydroxy acid used in the dissolution of calculi and used as an additive in various drug products to maintain consistency and other characteristics. Tienilic acid For the treatment of hypertension. Cyclandelate A vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis. Mepenzolate A postganglionic parasympathetic inhibitor that was previously approved for improving the healing of gastric ulcers, but has been discontinued. Belinostat A histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL). Sodium stibogluconate For the treatment of various types of a protozoal infection called leishmaniasis, which may result from sandfly bites in tropical and temperate parts of the world. Also investigated for use/treatment... Dersalazine Investigated for use/treatment in inflammatory bowel disease. Panobinostat A non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents. Methenamine A urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy. Phenyl aminosalicylate Not Annotated Triflusal Triflusal is indicated as prophylaxis of thromboembolic disorders. It has been registered in Spain and in other countries of Europe, South America and South Korea for the prevention of Stroke... Dehydroascorbic acid There is no approved indication for dehydroascorbic acid, but it has potential therapeutic use in patients with certain viruses and ischemic stroke. Teriflunomide A pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis. Adrafinil Used to relieve excessive sleepiness and inattention in elderly patients. Ibuproxam Ibuproxam is a non steroidal anti-inflammatory drug (NSAID). Clinofibrate Clinofibrate is a fibrate drug sold and marketed in Japan. Bromopride Bromopride in indicated in the treatment of nausea and vomiting, including PONV (post-operative nausea and vomiting), gastroesophageal reflux disease (GERD/GORD), as well as endoscopy preparation and radiographic studies of the... Benactyzine Benactyzine is an anticholinergic drug used as an antidepressant in the treatment of depression and associated anxiety. Benactyzine is no longer widely used in medicine, although it is still a... Sodium oxybate A central nervous system depressant used to treat cataplexy and excessive daytime sleepiness (EDS) associated with narcolepsy. Trimebutine A spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery. Iron sucrose An compound used as a source of iron in patients with iron deficiency anemia associated with chronic kidney disease (CKD). Iproclozide For the treatment of depression. Sodium aurothiomalate A disease-modifying antirheumatic drug (DMARD) indicated for the symptomatic treatment of arthritis. Propoxycaine Propoxycaine is a local anesthetic medication. It was used beginning in the 1950s during dental procedures . It has been combined with procaine to accelerate its onset of action and... L-tartaric acid Tartaric Acid is primarily indicated in conditions like Antiscorbutic, Antiseptic. Methyl salicylate A topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons. Octisalate Ingredient in sunscreens for protection against damage effects of sun light, provides protection from sunburns, aging and skin cancer. Homosalate As ingredient in many sunscreen for protection against sunburn, skin aging and skin cancer. Phenyl salicylate Pain and fever . Trolamine salicylate A medication used to relieve minor aches and pains of the muscles and joints. Calcium gluconate An ingredient found in a variety of supplements and vitamins, and is used to lower potassium in the blood or treat magnesium poisoning. Manganese gluconate An ingredient found in a variety of supplements and vitamins. Zinc gluconate An ingredient found in a variety of supplements and vitamins. Glycol salicylate A salicylate used to treat mild to moderate muscle pain. Nonivamide Nonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , . Ascorbyl glucoside Not Annotated Gleptoferron Colloid solution of ferric hydroxide, dextran & glucoheptonic acid. Tosedostat Tosedostat has been used in trials studying the treatment and supportive care of AML, Leukemia, Pancreas Cancer, Multiple Myeloma, and Pancreatic Cancer, among others. Tosedostat is an inhibitor of the... Laninamivir octanoate Laninamivir octanoate has been used in trials studying the treatment of Asthma. Lanopepden Lanopepden has been used in trials studying the treatment of Pneumonia, Infections, Bacterial, Skin Diseases, Infectious, and Skin Infections, Bacterial. CUDC-101 CUDC-101 has been used in trials studying the treatment of Cancer, Tumors, Liver Cancer, Breast Cancer, and Gastric Cancer, among others. CG-200745 Cg200745 has been used in trials studying the treatment of Solid Tumour. Propiverine An antimuscarinic agent used to treat urinary incontinence or increased urinary frequency or urgency. Ricolinostat Ricolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer. R-306465 R306465 has been used in trials studying the treatment of Neoplasms. Resminostat Resminostat has been used in trials studying the treatment of Sezary Syndrome, Mycosis fungoides, Hodgkin's Lymphoma, Hepatocellular Carcinoma, and Lymphoma, T-Cell, Cutaneous, among others. Nitroaspirin Nitroaspirin has been investigated for the treatment of Intermittent Claudication. Lifibrol Lifibrol has been used in trials studying the basic science of Hyperlipoproteinemia and Hypercholesterolemia. Propyl Gallate Propyl Gallate is under investigation in clinical trial NCT01450098 (A Study of LY2484595 in Healthy Subjects). Abexinostat Abexinostat has been used in trials studying the treatment of Sarcoma, Lymphoma, Leukemia, Lymphocytic, and Hodgkin Disease, among others. It is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase... Salirasib Salirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung. Malic acid Malic acid has been used in trials studying the treatment of Xerostomia, Depression, and Hypertension. Laninamivir Laninamivir has been used in trials studying the treatment of Influenza. Pyroxamide Pyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer, Precancerous Condition, and Myelodysplastic Syndromes, among others. Didox Didox has been used in trials studying the supportive care of Gastric Cancer. Quisinostat Quisinostat has been used in trials studying the treatment of Lymphoma, Neoplasms, Myelodysplastic Syndromes, and Advanced or Refractory Leukemia. Gluconic Acid An electrolyte supplement used in total parenteral nutrition. Mandelic acid Mandelic acid is an approved aromatic, alpha hydroxy acid . Mandelic acid is used as an ingredient in cosmetics and drug products applied topically. Calcium lactate An ingredient found in a variety of nutritional products. Hexobendine Hexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris. It has not been approved in the United States or the United Kingdom, but has... Bufexamac An NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses. Difemerine Not Annotated Mazaticol Not Annotated Poldine Not Annotated Aloxiprin Not Annotated Alginic acid Indicated for the management of gastric reflux, reflux oesophagitis, hiatus hernia, heartburn (including heartburn of pregnancy) and similar gastric distress . Guacetisal Not Annotated Bevonium Not Annotated Calcium pangamate Not Annotated Carbaspirin calcium Not Annotated Mifamurtide A muramyl dipeptide derivative used to treat high grade, resectable, non-metastatic osteosarcoma after surgical resection. Ethyl hydroxybenzoate Not Annotated Benorilate Not Annotated Sodium tartrate It acts as an emulsifier and pH control agent in food products , . In the laboratory, it is used while performing the Karl Fischer equation, which is used to... Magnesium gluconate A mineral supplement used to treat or prevent hypomagnesemia. Meclofenoxate Not Annotated Nifuroxazide Not Annotated Imidazole salicylate Not Annotated Hemoglobin crosfumaril Hemoglobin in which the alpha-subunit are cross-linked intramolecularly. Bismuth subgallate A medication used to deodorize flatulence and stools as well as hemostasis in soft tissue surgery. Choline salicylate The oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due... Thiosalicylic acid Not Annotated Butylparaben Not Annotated Benzylparaben Benzylparaben is used in allergenic testing. Propylparaben Propylparaben is used in allergenic testing. Methylparaben Methylparaben is used in allergenic testing. Calcium ascorbate Not Available Vanillic acid A flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13). 4-phospho-D-erythronic acid Not Available 3-deoxy-D-arabino-hexonic acid Not Available Mevalonic acid Not Available Glucaric acid Not Available 3-phospho-D-glyceric acid Not Available CTS-1027 CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus Infection. Squalamine Investigated for use/treatment in ovarian cancer, lung cancer, and macular degeneration. Glutamine hydroxamate Not Available Prenylamine Prenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias. Coleneuramide Coleneuramide is under investigation in clinical trial NCT00307749 (Safety and Efficacy of MCC-257 in the Treatment of Diabetic Polyneuropathy). Martinostat Martinostat is under investigation in clinical trial NCT03721211 (Imaging With [11C]Martinostat in Breast Cancer). Salvianolic acid A Salvianolic acid A is under investigation in clinical trial NCT03908242 (Phase I Study of Continuous Administration of Salvianolic Acid A Tablet). Tefinostat Tefinostat is under investigation in clinical trial NCT02759601 (Dose Escalation Trial of Tefinostat for Cancer Associated Inflamation in Hepatocellular Carcinoma (HCC)). Methyl vanillate Not Available Reposal Reposal is a barbiturate derivative invented in the 1960s in Denmark that has sedative, hypnotic and anticonvulsant properties. It was used primarily in the treatment of insomnia. p-Hydroxymercuribenzoic acid Not Available 4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamide Not Available 2-deoxy-2,3-dehydro-N-acetylneuraminic acid Not Available Ethyl salicylate Not Annotated Trichostatin A Not Available CGS-27023 Not Available Ilomastat Not Available 1-Naphthoxyacetic acid Not Available Hydracrylic acid Not Available 4-hydroxybenzoic acid Not Available
- Drugs & Drug Targets