Hydroxy Acids

Name
Hydroxy Acids
Accession Number
DBCAT000581
Description

Organic compounds containing both the hydroxyl and carboxyl radicals.

Drugs
DrugDrug Description
Ascorbic acidA vitamin used to correct vitamin C deficiency and to increase the intestinal absorption of iron.
TrospiumAn antimuscarinic agent used to treat the symptoms of overactive bladder (OAB).
Aminosalicylic acidAn aminosalicylate drug used to induce remission in ulcerative colitis.
Calcium glucoheptonateA calcium supplement combined with calcium gluconate to treat hypocalcemia and maintain calcium levels.
Acetohydroxamic acidA synthetic urea derivative used to treat urea splitting bacterial infections of the urinary tract.
ZanamivirA neuraminidase inhibitor used to treat influenza A and B.
BacitracinA cyclic polypeptide antibiotic used to prevent wound infections, treat pneumonia and empyema in infants, and to treat skin and eye infections.
DeferoxamineA chelating agent used to treat iron or aluminum toxicity and some blood transfusion dependent anemias.
ClidiniumA synthetic anticholinergic used to treat peptic ulcer disease, colicky abdominal pain, diverticulitis, and IBS.
MarimastatFor the treatment of various cancers
ProparacaineA topical anesthetic used for ophthalmic practice.
DiflunisalAn NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis.
Etacrynic acidA diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease.
Salicylic acidAn acid used to treat acne, psoriasis, calluses, corns, keratosis pilaris, and warts.
BalsalazideAn aminosalicylate used to treat ulcerative colitis.
OxybutyninAn antimuscarinic agent that reduces detrusor muscle activity, relaxing the bladder and preventing the urge to void.
RabeprazoleA proton pump inhibitor used to help gastrointestinal ulcers heal, to treat symptoms of gastroesophageal reflux disease (GERD), to eradicate Helicobacter pylori, and to treat hypersecretory conditions such as Zollinger-Ellison Syndrome.
TrimetrexateA folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin.
OlsalazineAn anti-inflammatory agent used in the treatment of inflammatory bowel disease and ulcerative colitis.
Bismuth subsalicylateAn antidiarrheal and anti-inflammatory agent used for symptomatic treatment of nausea, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
Magnesium salicylateAn NSAID analgesic used in the symptomatic relief of mild to moderate muscular pain.
SalsalateA nonsteroidal anti-inflammatory agent used in the symptomatic relief of rheumatoid arthritis, osteoarthritis and related rheumatic disorders.
Choline magnesium trisalicylateCholine magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.
gamma-Hydroxybutyric acidUsed as a general anesthetic, to treat conditions such as insomnia, clinical depression, narcolepsy, and alcoholism, and to improve athletic performance.
DimenoxadolDimenoxadol is an opioid analgesic which produces typical opioid effects such as analgesia and sedation. It is structurally similar to methadone and is a benzilic acid derivative. In the United...
SC-74020Not Available
CoprogenNot Available
PhosphoenolpyruvateNot Available
Benzhydroxamic AcidNot Available
WAY-151693Not Available
6-phospho-D-gluconic acidNot Available
Benzoylformic AcidNot Available
VorinostatA histone deacetylase (HDAC) inhibitor used for the treatment of cutaneous manifestations in patients with progressive, persistent, or recurrent cutaneous T- cell lymphoma (CTCL) following prior systemic therapies.
P-Anisic AcidNot Available
2,4-Dihydroxybenzoic AcidNot Available
Glycolic acidNot Available
GallichromeNot Available
2-Keto-3-DeoxygluconateNot Available
3-hydroxyanthranilic acidAn oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
XylarohydroxamateNot Available
3-Dehydroquinic AcidNot Available
3,4-Dihydroxybenzoic AcidNot Available
BalanolNot Available
Shikimate-3-PhosphateNot Available
3-DehydroshikimateNot Available
Bb-3497Not Available
Lactic acidAn emollient and keratolytic used agent in various cosmetic products and used as an additive in various pharmaceutical products for its antibacterial properties.
4-Phospho-D-erythronohydroxamic acidNot Available
GluconolactoneA polyhydroxy acid used in the dissolution of calculi and used as an additive in various drug products to maintain consistency and other characteristics.
Tienilic acidFor the treatment of hypertension.
CyclandelateA vasodilator used for the treatment of various blood vessel diseases, such as claudication and arteriosclerosis.
MepenzolateA postganglionic parasympathetic inhibitor that was previously approved for improving the healing of gastric ulcers, but has been discontinued.
BelinostatA histone deacetylase (HDAC) inhibitor used for the treatment of patients with relapsed or refractory peripheral T-cell lymphoma (PTCL).
Sodium stibogluconateFor the treatment of various types of a protozoal infection called leishmaniasis, which may result from sandfly bites in tropical and temperate parts of the world. Also investigated for use/treatment...
DersalazineInvestigated for use/treatment in inflammatory bowel disease.
PanobinostatA non-selective histone deacetylase inhibitor used to treat multiple myeloma in combination with other antineoplastic agents.
MethenamineA urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy.
Phenyl aminosalicylateNot Annotated
TriflusalTriflusal is indicated as prophylaxis of thromboembolic disorders. It has been registered in Spain and in other countries of Europe, South America and South Korea for the prevention of Stroke...
Dehydroascorbic acidThere is no approved indication for dehydroascorbic acid, but it has potential therapeutic use in patients with certain viruses and ischemic stroke.
TeriflunomideA pyrimidine synthesis inhibitor with anti-inflammatory and immunomodulatory properties used to treat patients with the relapsing-remitting form of multiple sclerosis.
AdrafinilUsed to relieve excessive sleepiness and inattention in elderly patients.
IbuproxamIbuproxam is a non steroidal anti-inflammatory drug (NSAID).
ClinofibrateClinofibrate is a fibrate drug sold and marketed in Japan.
BromoprideBromopride in indicated in the treatment of nausea and vomiting, including PONV (post-operative nausea and vomiting), gastroesophageal reflux disease (GERD/GORD), as well as endoscopy preparation and radiographic studies of the...
BenactyzineBenactyzine is an anticholinergic drug used as an antidepressant in the treatment of depression and associated anxiety. Benactyzine is no longer widely used in medicine, although it is still a...
Sodium oxybateA central nervous system depressant used to treat cataplexy and excessive daytime sleepiness (EDS) associated with narcolepsy.
TrimebutineA spasmolytic agent used for the symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery.
Iron sucroseAn compound used as a source of iron in patients with iron deficiency anemia associated with chronic kidney disease (CKD).
IproclozideFor the treatment of depression.
Sodium aurothiomalateA disease-modifying antirheumatic drug (DMARD) indicated for the symptomatic treatment of arthritis.
PropoxycainePropoxycaine is a local anesthetic medication. It was used beginning in the 1950s during dental procedures . It has been combined with procaine to accelerate its onset of action and...
L-tartaric acidTartaric Acid is primarily indicated in conditions like Antiscorbutic, Antiseptic.
Methyl salicylateA topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons.
OctisalateIngredient in sunscreens for protection against damage effects of sun light, provides protection from sunburns, aging and skin cancer.
HomosalateAs ingredient in many sunscreen for protection against sunburn, skin aging and skin cancer.
Phenyl salicylatePain and fever .
Trolamine salicylateA medication used to relieve minor aches and pains of the muscles and joints.
Calcium gluconateAn ingredient found in a variety of supplements and vitamins, and is used to lower potassium in the blood or treat magnesium poisoning.
Manganese gluconateAn ingredient found in a variety of supplements and vitamins.
Zinc gluconateAn ingredient found in a variety of supplements and vitamins.
Glycol salicylateA salicylate used to treat mild to moderate muscle pain.
NonivamideNonivamide is used as a topical analgesic and is also used as a flavoring ingredient , , .
Ascorbyl glucosideNot Annotated
GleptoferronColloid solution of ferric hydroxide, dextran & glucoheptonic acid.
TosedostatTosedostat has been used in trials studying the treatment and supportive care of AML, Leukemia, Pancreas Cancer, Multiple Myeloma, and Pancreatic Cancer, among others. Tosedostat is an inhibitor of the...
Laninamivir octanoateLaninamivir octanoate has been used in trials studying the treatment of Asthma.
LanopepdenLanopepden has been used in trials studying the treatment of Pneumonia, Infections, Bacterial, Skin Diseases, Infectious, and Skin Infections, Bacterial.
CUDC-101CUDC-101 has been used in trials studying the treatment of Cancer, Tumors, Liver Cancer, Breast Cancer, and Gastric Cancer, among others.
CG-200745Cg200745 has been used in trials studying the treatment of Solid Tumour.
PropiverineAn antimuscarinic agent used to treat urinary incontinence or increased urinary frequency or urgency.
RicolinostatRicolinostat is under investigation for the treatment of Breast Carcinoma and Metastatic Breast Cancer.
R-306465R306465 has been used in trials studying the treatment of Neoplasms.
ResminostatResminostat has been used in trials studying the treatment of Sezary Syndrome, Mycosis fungoides, Hodgkin's Lymphoma, Hepatocellular Carcinoma, and Lymphoma, T-Cell, Cutaneous, among others.
NitroaspirinNitroaspirin has been investigated for the treatment of Intermittent Claudication.
LifibrolLifibrol has been used in trials studying the basic science of Hyperlipoproteinemia and Hypercholesterolemia.
Propyl GallatePropyl Gallate is under investigation in clinical trial NCT01450098 (A Study of LY2484595 in Healthy Subjects).
AbexinostatAbexinostat has been used in trials studying the treatment of Sarcoma, Lymphoma, Leukemia, Lymphocytic, and Hodgkin Disease, among others. It is a novel, broad-spectrum hydroxamic acid-based inhibitor of histone deacetylase...
SalirasibSalirasib has been used in trials studying the diagnostic of Carcinoma, Non-Small-Cell Lung.
Malic acidMalic acid has been used in trials studying the treatment of Xerostomia, Depression, and Hypertension.
LaninamivirLaninamivir has been used in trials studying the treatment of Influenza.
PyroxamidePyroxamide has been used in trials studying the treatment of Leukemia, Lymphoma, Small Intestine Cancer, Precancerous Condition, and Myelodysplastic Syndromes, among others.
DidoxDidox has been used in trials studying the supportive care of Gastric Cancer.
QuisinostatQuisinostat has been used in trials studying the treatment of Lymphoma, Neoplasms, Myelodysplastic Syndromes, and Advanced or Refractory Leukemia.
Gluconic AcidAn electrolyte supplement used in total parenteral nutrition.
Mandelic acidMandelic acid is an approved aromatic, alpha hydroxy acid . Mandelic acid is used as an ingredient in cosmetics and drug products applied topically.
Calcium lactateAn ingredient found in a variety of nutritional products.
HexobendineHexobendine is a medication used to cause vasodilation, to treat several conditions including angina pectoris. It has not been approved in the United States or the United Kingdom, but has...
BufexamacAn NSAID used to treat skin conditions like atopic eczema and inflammatory dermatoses.
DifemerineNot Annotated
MazaticolNot Annotated
PoldineNot Annotated
AloxiprinNot Annotated
Alginic acidIndicated for the management of gastric reflux, reflux oesophagitis, hiatus hernia, heartburn (including heartburn of pregnancy) and similar gastric distress .
GuacetisalNot Annotated
BevoniumNot Annotated
Calcium pangamateNot Annotated
Carbaspirin calciumNot Annotated
MifamurtideA muramyl dipeptide derivative used to treat high grade, resectable, non-metastatic osteosarcoma after surgical resection.
Ethyl hydroxybenzoateNot Annotated
BenorilateNot Annotated
Sodium tartrateIt acts as an emulsifier and pH control agent in food products , . In the laboratory, it is used while performing the Karl Fischer equation, which is used to...
Magnesium gluconateA mineral supplement used to treat or prevent hypomagnesemia.
MeclofenoxateNot Annotated
NifuroxazideNot Annotated
Imidazole salicylateNot Annotated
Hemoglobin crosfumarilHemoglobin in which the alpha-subunit are cross-linked intramolecularly.
Bismuth subgallateA medication used to deodorize flatulence and stools as well as hemostasis in soft tissue surgery.
Choline salicylateThe oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due...
Thiosalicylic acidNot Annotated
ButylparabenNot Annotated
BenzylparabenBenzylparaben is used in allergenic testing.
PropylparabenPropylparaben is used in allergenic testing.
MethylparabenMethylparaben is used in allergenic testing.
Calcium ascorbateNot Available
Vanillic acidA flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13).
4-phospho-D-erythronic acidNot Available
3-deoxy-D-arabino-hexonic acidNot Available
Mevalonic acidNot Available
Glucaric acidNot Available
3-phospho-D-glyceric acidNot Available
CTS-1027CTS-1027 has been used in trials studying the treatment of Hepatitis C and Chronic Hepatitis C Virus Infection.
SqualamineInvestigated for use/treatment in ovarian cancer, lung cancer, and macular degeneration.
Glutamine hydroxamateNot Available
PrenylaminePrenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
ColeneuramideColeneuramide is under investigation in clinical trial NCT00307749 (Safety and Efficacy of MCC-257 in the Treatment of Diabetic Polyneuropathy).
MartinostatMartinostat is under investigation in clinical trial NCT03721211 (Imaging With [11C]Martinostat in Breast Cancer).
Salvianolic acid ASalvianolic acid A is under investigation in clinical trial NCT03908242 (Phase I Study of Continuous Administration of Salvianolic Acid A Tablet).
TefinostatTefinostat is under investigation in clinical trial NCT02759601 (Dose Escalation Trial of Tefinostat for Cancer Associated Inflamation in Hepatocellular Carcinoma (HCC)).
Methyl vanillateNot Available
ReposalReposal is a barbiturate derivative invented in the 1960s in Denmark that has sedative, hypnotic and anticonvulsant properties. It was used primarily in the treatment of insomnia.
p-Hydroxymercuribenzoic acidNot Available
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamideNot Available
2-deoxy-2,3-dehydro-N-acetylneuraminic acidNot Available
Ethyl salicylateNot Annotated
Trichostatin ANot Available
CGS-27023Not Available
IlomastatNot Available
1-Naphthoxyacetic acidNot Available
Hydracrylic acidNot Available
4-hydroxybenzoic acidNot Available
Drugs & Drug Targets
DrugTargetType
Ascorbic acidProlyl 4-hydroxylase subunit alpha-1target
Ascorbic acidProcollagen-lysine,2-oxoglutarate 5-dioxygenase 1target
Ascorbic acidHyaluronate lyasetarget
Ascorbic acidDNAtarget
Ascorbic acidXylose isomerasetarget
Ascorbic acidProcollagen-lysine,2-oxoglutarate 5-dioxygenase 2target
Ascorbic acidPhytanoyl-CoA dioxygenase, peroxisomaltarget
Ascorbic acidProcollagen-lysine,2-oxoglutarate 5-dioxygenase 3target
Ascorbic acidGamma-butyrobetaine dioxygenasetarget
Ascorbic acidDopamine beta-hydroxylasetarget
Ascorbic acidPeptidyl-glycine alpha-amidating monooxygenasetarget
Ascorbic acidProlyl 3-hydroxylase 1target
Ascorbic acid2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2target
Ascorbic acidAlpha-ketoglutarate-dependent dioxygenase alkB homolog 2target
Ascorbic acidProlyl 3-hydroxylase 2target
Ascorbic acidProlyl 3-hydroxylase 3target
Ascorbic acid2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1target
Ascorbic acidEgl nine homolog 2target
Ascorbic acidAlpha-ketoglutarate-dependent dioxygenase alkB homolog 3target
Ascorbic acidLysine-specific demethylase 5Dtarget
Ascorbic acidEgl nine homolog 1target
Ascorbic acidEgl nine homolog 3target
Ascorbic acidTrimethyllysine dioxygenase, mitochondrialtarget
Ascorbic acidTransmembrane prolyl 4-hydroxylasetarget
Ascorbic acidSolute carrier family 23 member 1transporter
Ascorbic acidSolute carrier family 23 member 2transporter
Ascorbic acidSolute carrier family 2, facilitated glucose transporter member 1transporter
Ascorbic acidSolute carrier family 2, facilitated glucose transporter member 3transporter
Ascorbic acidSolute carrier family 2, facilitated glucose transporter member 4transporter
Ascorbic acidSerum albumincarrier
Ascorbic acidThioredoxin reductase 1, cytoplasmicenzyme
TrospiumMuscarinic acetylcholine receptor M1target
TrospiumCytochrome P450 2D6enzyme
TrospiumMuscarinic acetylcholine receptor M3target
Aminosalicylic acidGroup IIE secretory phospholipase A2target
Aminosalicylic acidProstaglandin G/H synthase 2target
Aminosalicylic acidArachidonate 5-lipoxygenasetarget
Aminosalicylic acidInhibitor of nuclear factor kappa-B kinase subunit alphatarget
Aminosalicylic acidMyeloperoxidaseenzyme
Acetohydroxamic acidUrease subunit alphatarget
Acetohydroxamic acidMacrophage metalloelastasetarget
ZanamivirNeuraminidasetarget
ZanamivirNeuraminidasetarget
ZanamivirSialidase-2target
BacitracinAlpha-2-macroglobulintarget
BacitracinInsulin-degrading enzymetarget
BacitracinC55-isoprenyl pyrophosphatetarget
BacitracinBacitracin transport ATP-binding protein BcrAtransporter
BacitracinBacitracin transport permease protein BCRBtransporter
BacitracinBacitracin transport permease protein BcrCtransporter
DeferoxamineXanthine dehydrogenase/oxidaseenzyme
DeferoxamineIrontarget
DeferoxamineAluminumtarget
DeferoxamineAmyloid beta A4 proteintarget
ClidiniumMuscarinic acetylcholine receptor M1target
Marimastat72 kDa type IV collagenasetarget
MarimastatMatrix metalloproteinase-9target
MarimastatStromelysin-1target
MarimastatInterstitial collagenasetarget
MarimastatStromelysin-2target
MarimastatMatrilysintarget
MarimastatNeutrophil collagenasetarget
MarimastatStromelysin-3target
MarimastatMacrophage metalloelastasetarget
MarimastatCollagenase 3target
MarimastatMatrix metalloproteinase-14target
MarimastatMatrix metalloproteinase-15target
MarimastatMatrix metalloproteinase-16target
MarimastatMatrix metalloproteinase-17target
MarimastatMatrix metalloproteinase-19target
MarimastatMatrix metalloproteinase-20target
MarimastatMatrix metalloproteinase-21target
MarimastatMatrix metalloproteinase-23target
MarimastatMatrix metalloproteinase-24target
MarimastatMatrix metalloproteinase-25target
MarimastatMatrix metalloproteinase-26target
MarimastatMatrix metalloproteinase-27target
MarimastatMatrix metalloproteinase-28target
ProparacaineSodium channel protein type 10 subunit alphatarget
DiflunisalProstaglandin G/H synthase 1target
DiflunisalProstaglandin G/H synthase 2target
DiflunisalTransthyretincarrier
DiflunisalSerum albumincarrier
DiflunisalSolute carrier family 22 member 6transporter
DiflunisalUDP-glucuronosyltransferase 1-8enzyme
DiflunisalUDP-glucuronosyltransferase 1-9enzyme
Etacrynic acidSolute carrier family 12 member 1target
Etacrynic acidSodium/potassium-transporting ATPase subunit alpha-1target
Etacrynic acidGlutathione S-transferase A2enzyme
Etacrynic acidSerum albumincarrier
Etacrynic acidSolute carrier family 22 member 6transporter
Etacrynic acidLymphoid enhancer-binding factor 1target
Etacrynic acidGlutathione S-transferase Ptarget
Salicylic acidSerum albumincarrier
Salicylic acidProstaglandin G/H synthase 1target
Salicylic acidProstaglandin G/H synthase 2target
Salicylic acidAldo-keto reductase family 1 member C1target
Salicylic acidSolute carrier family 22 member 6transporter
Salicylic acidSolute carrier family 22 member 10transporter
Salicylic acidSolute carrier family 22 member 8transporter
Salicylic acidSolute carrier family 22 member 11transporter
Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
Salicylic acidMonocarboxylate transporter 1transporter
Salicylic acidSolute carrier family 22 member 7transporter
Salicylic acidCytochrome P450 2C9enzyme
BalsalazideProstaglandin G/H synthase 1target
BalsalazideProstaglandin G/H synthase 2target
BalsalazideArachidonate 5-lipoxygenasetarget
BalsalazidePeroxisome proliferator-activated receptor gammatarget
BalsalazideNADPH azoreductaseenzyme
OxybutyninMuscarinic acetylcholine receptor M1target
OxybutyninMuscarinic acetylcholine receptor M2target
OxybutyninMuscarinic acetylcholine receptor M3target
OxybutyninCytochrome P450 3A4enzyme
OxybutyninCytochrome P450 2C8enzyme
OxybutyninCytochrome P450 2D6enzyme
OxybutyninCytochrome P450 3A5enzyme
OxybutyninAlpha-1-acid glycoprotein 1carrier
OxybutyninSerum albumincarrier
RabeprazolePotassium-transporting ATPase alpha chain 1target
RabeprazoleCytochrome P450 3A4enzyme
RabeprazoleCytochrome P450 2C19enzyme
RabeprazoleATP-binding cassette sub-family G member 2transporter
RabeprazoleCytochrome P450 1A1enzyme
RabeprazoleCytochrome P450 1A2enzyme
RabeprazoleCytochrome P450 2C9enzyme
RabeprazoleCytochrome P450 2D6enzyme
RabeprazoleCytochrome P450 2C8enzyme
TrimetrexateDihydrofolate reductasetarget
TrimetrexateDihydrofolate reductaseenzyme
TrimetrexateFolate transporter 1transporter
OlsalazineInterferon gammatarget
OlsalazineThiopurine S-methyltransferasetarget
Bismuth subsalicylateSerum albumincarrier
Bismuth subsalicylateSerotransferrincarrier
Magnesium salicylateSerum albumincarrier
Magnesium salicylateProstaglandin G/H synthase 1target
Magnesium salicylateProstaglandin G/H synthase 2target
SalsalateProstaglandin G/H synthase 1target
SalsalateProstaglandin G/H synthase 2target
Choline magnesium trisalicylateProstaglandin G/H synthase 1target
Choline magnesium trisalicylateProstaglandin G/H synthase 2target
gamma-Hydroxybutyric acidMonocarboxylate transporter 2transporter
gamma-Hydroxybutyric acidMonocarboxylate transporter 1transporter
gamma-Hydroxybutyric acidMonocarboxylate transporter 4transporter
gamma-Hydroxybutyric acidGamma-hydroxybutyrate (GHB) receptortarget
gamma-Hydroxybutyric acidGamma-aminobutyric acid receptor subunit beta-1target
SC-7402072 kDa type IV collagenasetarget
CoprogenIron(3+)-hydroxamate-binding protein FhuDtarget
Phosphoenolpyruvate2-dehydro-3-deoxyphosphooctonate aldolasetarget
PhosphoenolpyruvateBeta-enolasetarget
PhosphoenolpyruvatePhosphoenolpyruvate carboxykinase, cytosolic [GTP]target
Phosphoenolpyruvate2-dehydro-3-deoxyphosphooctonate aldolasetarget
PhosphoenolpyruvatePhospho-2-dehydro-3-deoxyheptonate aldolasetarget
PhosphoenolpyruvatePhospho-2-dehydro-3-deoxyheptonate aldolase, Phe-sensitivetarget
PhosphoenolpyruvateCapsule biosynthesis proteintarget
PhosphoenolpyruvateSolute carrier organic anion transporter family member 2A1transporter
WAY-151693Collagenase 3target
6-phospho-D-gluconic acid6-phosphogluconate dehydrogenase, decarboxylatingtarget
6-phospho-D-gluconic acidGlucose-6-phosphate isomerasetarget
6-phospho-D-gluconic acidThermoresistant gluconokinasetarget
Benzoylformic AcidHydroxyacid oxidase 1target
VorinostatHistone deacetylase 1target
VorinostatHistone deacetylase 2target
VorinostatHistone deacetylase 3target
VorinostatHistone deacetylase 6target
VorinostatHistone deacetylase 8target
VorinostatAcetoin utilization proteintarget
P-Anisic AcidGroup IIE secretory phospholipase A2target
P-Anisic AcidPhospholipase A2target
2,4-Dihydroxybenzoic Acidp-hydroxybenzoate hydroxylasetarget
2,4-Dihydroxybenzoic Acidp-hydroxybenzoate hydroxylasetarget
Glycolic acidGlucose-6-phosphate 1-dehydrogenasetarget
GallichromeIron(3+)-hydroxamate-binding protein FhuDtarget
2-Keto-3-Deoxygluconate2-keto-3-deoxy-gluconate kinasetarget
3-hydroxyanthranilic acidTrans-2,3-dihydro-3-hydroxyanthranilate isomerasetarget
XylarohydroxamateGlucarate dehydratasetarget
3-Dehydroquinic Acid3-dehydroquinate dehydratasetarget
BalanolcAMP-dependent protein kinase catalytic subunit alphatarget
Shikimate-3-Phosphate3-phosphoshikimate 1-carboxyvinyltransferasetarget
Shikimate-3-Phosphate3-phosphoshikimate 1-carboxyvinyltransferasetarget
3-Dehydroshikimate3-dehydroquinate dehydratasetarget
3-Dehydroshikimate3-dehydroquinate dehydratasetarget
Bb-3497Peptide deformylasetarget
Bb-3497Peptide deformylase, mitochondrialtarget
Lactic acidBifunctional protein PutAtarget
Lactic acidNimA-related proteintarget
Lactic acidMonocarboxylate transporter 2transporter
Lactic acidSolute carrier organic anion transporter family member 2B1transporter
Lactic acidMonocarboxylate transporter 1transporter
Lactic acidMonocarboxylate transporter 10transporter
Lactic acidSolute carrier organic anion transporter family member 2A1transporter
Lactic acidMonocarboxylate transporter 4transporter
4-Phospho-D-erythronohydroxamic acidRibose-5-phosphate isomerase Btarget
GluconolactoneLactase-phlorizin hydrolasetarget
Tienilic acidCytochrome P450 2C9enzyme
CyclandelateVoltage-dependent calcium channel subunit alpha-2/delta-1target
CyclandelateLiver carboxylesterase 1target
CyclandelateCytochrome P450 3A4enzyme
MepenzolateMuscarinic acetylcholine receptor M1target
MepenzolateMuscarinic acetylcholine receptor M3target
BelinostatHistone deacetylasetarget
BelinostatCytochrome P450 1A2enzyme
BelinostatUDP-glucuronosyltransferase 1-4enzyme
BelinostatCytochrome P450 2C8enzyme
BelinostatCytochrome P450 2C9enzyme
BelinostatP-glycoprotein 1transporter
BelinostatCytochrome P450 3A4enzyme
Sodium stibogluconateDNA topoisomerase 1target
PanobinostatCytochrome P450 2D6enzyme
PanobinostatCytochrome P450 3A4enzyme
PanobinostatP-glycoprotein 1transporter
PanobinostatHistone deacetylasetarget
TriflusalProstaglandin G/H synthase 1target
TriflusalNuclear factor NF-kappa-B p105 subunittarget
TriflusalNitric oxide synthase, inducibletarget
TriflusalcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
TriflusalSerum albumincarrier
Dehydroascorbic acidSolute carrier family 2, facilitated glucose transporter member 1transporter
TeriflunomideATP-binding cassette sub-family G member 2transporter
TeriflunomideDihydroorotate dehydrogenase (quinone), mitochondrialtarget
TeriflunomideCytochrome P450 2C8enzyme
TeriflunomideSolute carrier organic anion transporter family member 1B1transporter
TeriflunomideCytochrome P450 1A2enzyme
ClinofibratePeroxisome proliferator-activated receptor alphatarget
ClinofibratePeroxisome proliferator-activated receptor gammatarget
ClinofibratePeroxisome proliferator-activated receptor deltatarget
BromoprideDopamine D2 receptortarget
Sodium oxybateSuccinate-semialdehyde dehydrogenase, mitochondrialenzyme
Sodium oxybateHydroxyacid-oxoacid transhydrogenase, mitochondrialenzyme
TrimebutineMu-type opioid receptortarget
TrimebutineVoltage-dependent L-type calcium channeltarget
TrimebutineCalcium-activated potassium channeltarget
TrimebutineVoltage-dependent T-type calcium channeltarget
TrimebutineMuscarinic acetylcholine receptor M1target
TrimebutineMuscarinic acetylcholine receptor M2target
TrimebutineMuscarinic acetylcholine receptor M3target
TrimebutineMuscarinic acetylcholine receptor M4target
TrimebutineCytochrome P450 3A4enzyme
Sodium aurothiomalateUDP-glucuronosyltransferase 1-1enzyme
PropoxycaineLiver carboxylesterase 1enzyme
PropoxycaineVoltage-gated sodium channel alpha subunittarget
L-tartaric acidGalactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1enzyme
L-tartaric acidHypoxia-inducible factor 1-alpha inhibitorenzyme
HomosalateProgesterone receptortarget
HomosalateAndrogen receptortarget
HomosalateEstrogen receptor alphatarget
Phenyl salicylateProstaglandin G/H synthase 1target
Phenyl salicylateProstaglandin G/H synthase 2target
Trolamine salicylateProstaglandin G/H synthase 1target
Trolamine salicylateProstaglandin G/H synthase 2target
Glycol salicylateProstaglandin G/H synthase 1target
Glycol salicylateProstaglandin G/H synthase 2target
NonivamideTransient receptor potential cation channel subfamily V member 1target
TosedostatPuromycin-sensitive aminopeptidasetarget
TosedostatLeukotriene A-4 hydrolasetarget
PropiverineMuscarinic acetylcholine receptor M1target
PropiverineMuscarinic acetylcholine receptor M2target
PropiverineMuscarinic acetylcholine receptor M3target
PropiverineMuscarinic acetylcholine receptor M4target
PropiverineMuscarinic acetylcholine receptor M5target
PropiverineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
PropiverineAlpha-1A adrenergic receptortarget
PropiverineCytochrome P450 3A4enzyme
PropiverineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
PropiverineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
NitroaspirinProstaglandin G/H synthase 1target
Propyl GallateEstrogen receptor alphatarget
AbexinostatHistone deacetylase 1target
BufexamacProstaglandin G/H synthase 1target
BufexamacProstaglandin G/H synthase 2target
BufexamacHistone deacetylase 6target
BufexamacHistone deacetylase 10target
MifamurtideToll-like receptor 4target
MifamurtideNucleotide-binding oligomerization domain-containing protein 2target
Magnesium gluconateHexokinaseenzyme
Magnesium gluconateCreatine kinase B-typeenzyme
Magnesium gluconateTyrosine-protein kinase ABL1enzyme
Magnesium gluconateATP synthase subunit delta, mitochondrialenzyme
Magnesium gluconateAdenylate cyclase type 1enzyme
Magnesium gluconateGuanylate cyclase soluble subunit alpha-2enzyme
Magnesium gluconate6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1enzyme
Magnesium gluconatePhosphoribosylpyrophosphate synthetaseenzyme
Magnesium gluconateSodium/potassium-transporting ATPase subunit alpha-1enzyme
Bismuth subgallateSerum albumincarrier
Choline salicylateCholine-phosphate cytidylyltransferase Btarget
Choline salicylateAcetylcholinesterasetarget
Choline salicylateCholine-phosphate cytidylyltransferase Atarget
Choline salicylatePhospholipase D2target
Choline salicylateCholinesterasetarget
Choline salicylatePhospholipase D1target
Choline salicylateSolute carrier family 22 member 2transporter
Choline salicylateSolute carrier family 22 member 1transporter
Choline salicylateSolute carrier family 22 member 3transporter
Choline salicylateSolute carrier family 22 member 5transporter
Choline salicylateSolute carrier family 22 member 4transporter
Choline salicylateCholine/ethanolaminephosphotransferase 1enzyme
Choline salicylateCholine transporter-like protein 1transporter
Choline salicylateCholine transporter-like protein 4transporter
Choline salicylateCholine transporter-like protein 3transporter
Choline salicylateCholine/ethanolamine kinaseenzyme
Choline salicylateCholine O-acetyltransferaseenzyme
Choline salicylateCholine kinase alphaenzyme
Choline salicylateCholine dehydrogenase, mitochondrialenzyme
Choline salicylateHigh affinity choline transporter 1transporter
Choline salicylateNeuronal acetylcholine receptor subunit alpha-7target
Vanillic acidChorismate--pyruvate lyasetarget
4-phospho-D-erythronic acidRibose-5-phosphate isomerase Btarget
Mevalonic acid3-hydroxy-3-methylglutaryl-coenzyme A reductasetarget
Glucaric acidGlucarate dehydratasetarget
3-phospho-D-glyceric acidTriosephosphate isomerasetarget
3-phospho-D-glyceric acid2,3-bisphosphoglycerate-independent phosphoglycerate mutasetarget
3-phospho-D-glyceric acidPhosphoglycerate mutase 2target
3-phospho-D-glyceric acidTriosephosphate isomerasetarget
3-phospho-D-glyceric acidPhosphoglycerate kinase 1target
3-phospho-D-glyceric acidBifunctional PGK/TIMtarget
CTS-1027Collagenase 3target
Glutamine hydroxamateGlutamine--fructose-6-phosphate aminotransferase [isomerizing]target
PrenylamineCalmodulintarget
PrenylamineMyosin light chain kinase 2, skeletal/cardiac muscletarget
PrenylamineCytochrome P450 3A4enzyme
Methyl vanillateEndo-1,4-beta-xylanase Ytarget
p-Hydroxymercuribenzoic acidCarbonic anhydrase 2target
4-(dimethylamino)-N-[7-(hydroxyamino)-7-oxoheptyl]benzamideHistone deacetylase 8target
2-deoxy-2,3-dehydro-N-acetylneuraminic acidHemagglutinin-neuraminidasetarget
2-deoxy-2,3-dehydro-N-acetylneuraminic acidSialidasetarget
2-deoxy-2,3-dehydro-N-acetylneuraminic acidNeuraminidasetarget
2-deoxy-2,3-dehydro-N-acetylneuraminic acidHemagglutinin-neuraminidasetarget
2-deoxy-2,3-dehydro-N-acetylneuraminic acidSialidase-2target
Trichostatin AHistone deacetylase 8target
Trichostatin AAcetoin utilization proteintarget
Trichostatin AHistone deacetylase 7target
CGS-27023Macrophage metalloelastasetarget
CGS-27023Interstitial collagenasetarget
IlomastatLethal factortarget
IlomastatDisintegrin and metalloproteinase domain-containing protein 28target
IlomastatAggrecan core proteintarget
1-Naphthoxyacetic acidGag-Pol polyproteintarget
1-Naphthoxyacetic acidGag-Pol polyproteintarget
Hydracrylic acidPimelyl-[acyl-carrier protein] methyl ester esterasetarget
4-hydroxybenzoic acidp-hydroxybenzoate hydroxylasetarget
4-hydroxybenzoic acidChorismate--pyruvate lyasetarget
4-hydroxybenzoic acidp-hydroxybenzoate hydroxylasetarget
4-hydroxybenzoic acid4-hydroxybenzoyl-CoA thioesterasetarget