Acids, Carbocyclic

Carboxylic acids that have a homocyclic ring structure in which all the ring atoms are carbon.
DrugDrug NameDrug Indication
DB00209TrospiumFor the treatment of overactive bladder with symptoms of urge urinary incontinence, urgency, and urinary frequency, detrusor instability and frequency of micturition.
DB00233Aminosalicylic AcidFor the treatment of tuberculosis
DB00271DiatrizoateUsed, alone or in combination, for a wide variety of diagnostic imaging methods, including angiography, urography, cholangiography, computed tomography, hysterosalpingography, and retrograde pyelography. It can be used for imaging the gastrointestinal tract in patients allergic to barium.
DB00302Tranexamic acidFor use in patients with hemophilia for short term use (two to eight days) to reduce or prevent hemorrhage and reduce the need for replacement therapy during and following tooth extraction. It can also be used for excessive bleeding in menstruation, surgery, or trauma cases.
DB00310ChlorthalidoneChlorthalidone is indicated in the management of hypertension either as the sole therapeutic agent or to enhance the effect of other antihypertensive drugs in the more severe forms of hypertension. Chlorthalidone is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Chlorthalidone has also been found useful in edema due to various forms of renal dysfunction, such as nephrotic syndrome, acute glomerulonephritis, and chronic renal failure.
DB00345Aminohippuric acidUsed to measure effective renal plasma flow (ERPF) and to determine the functional capacity of the tubular excretory mechanism.
DB00348NitisinoneUsed as an adjunct to dietary restriction of tyrosine and phenylalanine in the treatment of hereditary tyrosinemia type 1.
DB00391SulpirideSulpiride is indicated for the treatment of schizophrenia.
DB00409RemoxiprideRemoxipride is an atypical antipsychotic once used for the treatment of schizophrenia.
DB00422MethylphenidateMethylphenidate is indicated for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in patients 6 years of age and older and for the treatment of narcolepsy.
DB00480LenalidomideLenalidomide is indicated for the treatment of multiple myeloma in combination with dexamethasone. It is also indicated for the treatment of patients with transfusion-dependent anemia due to low- or intermediate- risk myelodysplastic syndromes (MDS) associated with a deletion 5q cytogenetic abnormality with or without additional cytogenetic abnormalities.
DB00522BentiromideIndicated as a screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy.
DB00573FenoprofenFor relief of the signs and symptoms of rheumatoid arthritis and osteoarthritis. Also for the relief of mild to moderate pain.
DB00586DiclofenacFor the acute and chronic treatment of signs and symptoms of osteoarthritis and rheumatoid arthritis.
DB00604CisaprideFor the symptomatic treatment of adult patients with nocturnal heartburn due to gastroesophageal reflux disease.
DB00619ImatinibFor the treatment of Philadelphia chromosome positive chronic myeloid leukemia (Ph+ CML), Ph+ acute lymphoblastic leukaemia, myelodysplastic/myeloproliferative diseases, aggressive systemic mastocytosis, hypereosinophilic syndrome and/or chronic eosinophilic leukemia (CEL), dermatofibrosarcoma protuberans, and malignant gastrointestinal stromal tumors (GIST).
DB00626BacitracinFor the treatment of infants with pneumonia and empyema caused by staphylococci shown to be susceptible to the drug. Also used in ointment form for topical treatment of a variety of localized skin and eye infections, as well as for the prevention of wound infections. Used against gram positive bacteria. Bacitracin is also used as an inhibitor of proteases and other enzymes. However, specific activity of bactracin's inhibition of protein disulfide isomerase has been called into question.
DB00662TrimethobenzamideFor the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.
DB00676Benzyl benzoateUsed to kill lice and the mites responsible for the skin condition scabies.
DB00695FurosemideFor the treatment of edema associated with congestive heart failure, cirrhosis of the liver, and renal disease, including the nephrotic syndrome. Also for the treatment of hypertension alone or in combination with other antihypertensive agents.
DB00721ProcaineUsed as a local anesthetic primarily in oral surgery
DB00771ClidiniumFor the treatment of peptic ulcer disease and also to help relieve abdominal or stomach spasms or cramps due to colicky abdominal pain, diverticulitis, and irritable bowel syndrome.
DB00784Mefenamic acidFor the treatment of rheumatoid arthritis, osteoarthritis, dysmenorrhea, and mild to moderate pain, inflammation, and fever.
DB00804DicyclomineFor the treatment of functional bowel/irritable bowel syndrome including Colicky abdominal pain; diverticulitis
DB00807ProparacaineUsed as a local (ophthalmic) anesthetic.
DB00861DiflunisalFor symptomatic treatment of mild to moderate pain accompanied by inflammation (e.g. musculoskeletal trauma, post-dental extraction, post-episiotomy), osteoarthritis, and rheumatoid arthritis.
DB00870SuprofenUsed as eye drops to inhibit the miosis (pupil constriction) that may occur during ocular surgery.
DB00887BumetanideFor the treatment of edema associated with congestive heart failure, hepatic and renal disease including the nephrotic syndrome.
DB00892OxybuprocaineUsed to temporarily numb the front surface of the eye so that the eye pressure can be measured or a foreign body removed.
DB00936Salicylic acidKey additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts.
DB00939Meclofenamic acidFor the relief of mild to moderate pain, for the treatment of primary dysmenorrhea and for the treatment of idiopathic heavy menstrual blood loss. Also for relief of the signs and symptoms of acute and chronic rheumatoid arthritis and osteoarthritis.
DB00945Acetylsalicylic acid**Pain, fever, and inflammation** Acetylsalicylic acid (ASA), in the regular tablet form (immediate-release), is indicated to relieve pain, fever, and inflammation associated with many conditions, including the flu, the common cold, neck and back pain, dysmenorrhea, headache, tooth pain, sprains, fractures, myositis, neuralgia, synovitis, arthritis, bursitis, burns, and various injuries. It is also used for symptomatic pain relief after surgical and dental procedures [FDA label]. The _extra strength_ formulation of acetylsalicylic acid is also indicated for the management migraine pain with photophobia (sensitivity to light) and phonophobia (sensitivity to sound)[FDA label]. **Other indications** ASA is also indicated for various other purposes, due to its ability to inhibit platelet aggregation. These include: Reducing the risk of cardiovascular death in suspected cases of myocardial infarction (MI) [FDA label]. Reducing the risk of a first non-fatal myocardial infarction in patients, and for reducing the risk of morbidity and mortality in cases of unstable angina and in those who have had a prior myocardial infarction [FDA label]. For reducing the risk of transient ischemic attacks (TIA) and to prevent atherothrombotic cerebral infarction (in conjunction with other treatments) [FDA label]. For the prevention of thromboembolism after hip replacement surgery [FDA label]. For decreasing platelet to platelet adhesion following carotid endarterectomy, aiding in the prevention of transient ischemic attacks (TIA) [FDA label]. Used for patients undergoing hemodialysis with a silicone rubber arteriovenous cannula inserted to prevent thrombosis at the insertion site [FDA Label]. **Important note regarding use of the extended-release formulation [F4405]** In the setting of acute myocardial infarction, or before percutaneous interventions, the extended-release form of acetylsalicylic acid should not be used. Use immediate-release formulations in scenarios requiring rapid onset of action [Label, F4405]. The extended-release form is taken to decrease the incidence of mortality and myocardial infarction (MI) for individuals diagnosed with chronic coronary artery disease (CAD), including patients with previous myocardial infarction (MI) or unstable angina or with chronic stable angina. Additionally, the extended-release form is used to decrease the risk of death and recurrent episodes of stroke in patients with a history of stroke or TIA [F4405].
DB00966TelmisartanUsed alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus, as well as the treatment of congestive heart failure (only in patients who cannot tolerate ACE inhibitors).
DB00979CyclopentolateUsed mainly to produce mydriasis and cycloplegia for diagnostic purposes.
DB00996GabapentinFor the management of postherpetic neuralgia in adults and as adjunctive therapy in the treatment of partial seizures with and without secondary generalization in patients over 12 years of age with epilepsy.
DB01009KetoprofenFor symptomatic treatment of acute and chronic rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, primary dysmenorrhea and mild to moderate pain associated with musculotendinous trauma (sprains and strains), postoperative (including dental surgery) or postpartum pain.
DB01014BalsalazideFor the treatment of mildly to moderately active ulcerative colitis.
DB01018GuanfacineFor use alone or in combination with other classes of antihypertensive agents in the management of hypertension. Has also been used for the treatment of attention deficit hyperactivity disorder (ADHD) in pediatric patients.
DB01035ProcainamideFor the treatment of life-threatening ventricular arrhythmias.
DB01041ThalidomideFor the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence.
DB01050IbuprofenIbuprofen is the most commonly used and prescribed NSAID. It is very common over the counter medication widely used as an analgesic, anti-inflammatory and antipyretic.[A39096] The use of ibuprofen and its enantiomer [DB09213] in a racemic mix is common for the management of mild to moderate pain related to dysmenorrhea, headache, migraine, postoperative dental pain, spondylitis, osteoarthritis, rheumatoid arthritis, and soft tissue disorder.[A39097] Due to its activity against prostaglandin and thromboxane synthesis, ibuprofen has been attributed to alteration of platelet function and prolongation of gestation and labor.[A39092] As ibuprofen is a widely used medication, the main therapeutic indications are: * Patent Ductus Arteriosus - it is a neonatal condition wherein the ductus arteriosus (blood vessel that connects the main pulmonary artery to the proximal descending aorta) fails to close after birth causing severe risk of heart failure. The prostaglandin inhibition of ibuprofen has been studied for the treatment of this condition as it is known that prostaglandin E2 is responsible for keeping the ductus arteriosus open.[A39100] * Rheumatoid- and osteo-arthritis - ibuprofen is very commonly used in the symptomatic treatment of inflammatory, musculoskeletal and rheumatic disorders.[A39176] * Cystic fibrosis - the use of high dosages of ibuprofen has been proven to decrease inflammation and decreasing polymorphonuclear cell influx in the lungs.[A39177] * Orthostatic hypotension - ibuprofen can induce sodium retention and antagonize the effect of diuretics which has been reported to be beneficial for patients with severe orthostatic hypotension.[A1651] * Dental pain - ibuprofen is used to manage acute and chronic orofacial pain.[A10901] * Minor pain - ibuprofen is widely used to reduce minor aches and pains as well as to reduce fever and manage dysmenorrhea. It is very commonly used for the relief of acute indications such as fever and tension headaches.[A39092] * Investigational uses - efforts have been put into developing ibuprofen for the prophylaxis of Alzheimer's disease, Parkinson disease, and breast cancer.[A39092]
DB01062OxybutyninFor the treatment of overactive bladder.
DB01086BenzocaineFor general use as a lubricant and topical anesthetic on esophagus, larynx, mouth, nasal cavity, rectum, respiratory tract or trachea, urinary tract, vagina. It is also used to suppress gag reflex.
DB01161ChloroprocaineFor the production of local anesthesia by infiltration and peripheral nerve block. They are not to be used for lumbar or caudal epidural anesthesia.
DB01168ProcarbazineFor use with other anticancer drugs for the treatment of stage III and stage IV Hodgkin's disease.
DB01171MoclobemideFor the treatment of major depressive disorder and bipolar disorder [A31901].
DB01233MetoclopramideFor the treatment of gastroesophageal reflux disease (GERD). It is also used in treating nausea and vomiting, and to increase gastric emptying.
DB01249IodixanolIodixanol is a contrast agent during coronary angiography.
DB01250OlsalazineFor the treatment of Inflammatory Bowel Disease and Ulcerative Colitis.
DB01283LumiracoxibFor the acute and chronic treatment of the signs and symptoms of osteoarthritis of the knee in adults.
DB01294Bismuth subsalicylateUsed to treat nausea, heartburn, indigestion, upset stomach, diarrhea, and other temporary discomforts of the stomach and gastrointestinal tract.
DB01362IohexolIohexol ia used in myelography, arthrography, nephroangiography, arteriography, and other radiographic procedures.
DB01393BezafibrateFor the treatment of primary hyperlipidaemia types IIa, IIb, III, IV and V (Fredrickson classification) corresponding to groups I, II and III of the European Atherosclerosis Society guidelines - when diet alone or improvements in lifestyle such as increased exercise or weight reduction do not lead to an adequate response. Also for the treatment of secondary hyperlipidaemias, e.g. severe hypertriglyceridemias, when sufficient improvement does not occur after correction of the underlying disorder (e.g. diabetes mellitus).
DB01397Magnesium salicylateMagnesium salicylate is a common analgesic and non-steroidal anti-inflammatory drug (NSAID) used to treat mild to moderate muscular pain
DB01399SalsalateFor relief of the signs and symptoms of rheumatoid arthritis, osteoarthritis and related rheumatic disorders.
DB01401Choline magnesium trisalicylateCholine magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.
DB01461DimenoxadolNot Available
DB01487EmbutramideNot Available
DB01578MetrizamideMetrizamide is used for lumbar, thoracic, cervical, and total columnar myelography to determine the presence of abnormalities in the spinal column, spinal canal, and central nervous system (CNS) as well as for cisternography by direct injection using standard radiologic techniques to visualize the basal cistern of the brain. For computerized tomography (CT) of the intracranial subarachnoid spaces and for ventriculography by direct injection using standard radiologic techniques to visualize the cerebral ventricles. Also used in pediatric angiocardiography to visualize lesions or malformations of the heart and obstructions or anomalies of the major thoracic vessels. Also used in adult peripheral arteriography to visualize specific regions of the vascular system and blood flow in such areas to help in the diagnosis and evaluation of neoplasms (known or suspected) or vascular diseases (congenital or acquired) that may cause changes in normal vascular anatomy or physiology. Metrizamide is also indicated in adults for intravenous digital arteriography of head and neck.
DB01609DeferasiroxFor the treatment of chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients 2 years of age and older.
DB01656RoflumilastRoflumilast is indicated as a treatment to reduce the risk of COPD exacerbations in patients with severe COPD associated with chronic bronchitis and a history of exacerbations. Roflumilast is not a bronchodilator and is not indicated for the relief of acute bronchospasm.
DB01681Benzene Hexacarboxylic AcidNot Available
DB01791PiclamilastNot Available
DB018803,4-Dihydroxycinnamic AcidNot Available
DB020243-phenylpropionic acidNot Available
DB02054GabaculineNot Available
DB02251O-SuccinylbenzoateNot Available
DB02266Flufenamic AcidNot Available
DB02279Benzoylformic AcidNot Available
DB02362Aminobenzoic acidNot Available
DB02715Compound 18Not Available
DB02746Phthalic AcidNot Available
DB02749Pyromellitic AcidNot Available
DB02793Isochorismic AcidNot Available
DB02795P-Anisic AcidNot Available
DB028392,4-Dihydroxybenzoic AcidNot Available
DB02877Arotinoid acidNot Available
DB030733-MethoxybenzamideNot Available
DB03126Mant-AdpNot Available
DB032434-FluorobenzylamineNot Available
DB03588Diphenylacetic AcidNot Available
DB036443-hydroxyanthranilic acidNot Available
DB03728p-Chlorobenzoic acidNot Available
DB03793Benzoic AcidNot Available
DB03849CilomilastInvestigated for use/treatment in chronic obstructive pulmonary disease (COPD).
DB038683-Dehydroquinic AcidNot Available
DB039463,4-Dihydroxybenzoic AcidNot Available
DB04066para-Coumaric AcidNot Available
DB04098BalanolNot Available
DB04166Anthranilic acidNot Available
DB04328Shikimate-3-PhosphateNot Available
DB043361-(4-Amidinophenyl)-3-(4-Chlorophenyl)UreaNot Available
DB043473-DehydroshikimateNot Available
DB04500AcedobenNot Available
DB04552Niflumic acidUsed in the treatment of rheumatoid arthritis.
DB04711IodipamideIodipamide is used as a contrast agent for cholecystography and intravenous cholangiography.
DB04822OxeladinNot Available
DB04838CyclandelateUsed in the treatment of various blood vessel diseases (e.g., claudication, arteriosclerosis and Raynaud's disease) and nighttime leg cramps.
DB04843MepenzolateFor use as adjunctive therapy in the treatment of peptic ulcer. It has not been shown to be effective in contributing to the healing of peptic ulcer, decreasing the rate of recurrence, or preventing complications.
DB04883DarusentanFor the treatment of congestive heart failure and hypertension.
DB04917RenzaprideFor the treatment of constipation-predominant irritable bowel syndrome (IBS-C).
DB04924ItoprideInvestigated for use/treatment in gastrointestinal diseases and disorders (miscellaneous).
DB04942TamibaroteneInvestigated for use/treatment in leukemia (unspecified).
DB05009ApadenosonInvestigated for use/treatment in cardiovascular disorders and inflammatory disorders (unspecified).
DB05050ADL5859Investigated for use/treatment in pain (acute or chronic).
DB05130INCB3284Investigated for use/treatment in inflammatory disorders (unspecified).
DB05191Atl146eInvestigated for use/treatment in inflammatory disorders (unspecified).
DB05227APD791For the treatment and prophylaxis of arterial thrombosis.
DB05255RonacaleretPost-menopausal women with osteoporosis
DB05303OMS-103HPInvestigated for use/treatment in inflammatory disorders (unspecified), knee replacement, orthopedic surgery, and pain (acute or chronic).
DB05507VX-765Investigated for use/treatment in inflammatory disorders (unspecified) and psoriasis and psoriatic disorders.
DB05542NaronaprideInvestigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis.
DB05676ApremilastInvestigated for use/treatment in psoriasis and psoriatic disorders.
DB05678SLx-4090Investigated for use/treatment in hyperlipidemia.
DB06070SNX-5422Investigated for use/treatment in cancer/tumors (unspecified).
DB06082PX-478Investigated for use/treatment in cancer/tumors (unspecified).
DB06188IspinesibInvestigated for use/treatment in breast cancer, lung cancer, solid tumors, renal cell carcinoma, pediatric indications, ovarian cancer, and head and neck cancer.
DB06190SolabegronInvestigated for use/treatment in diabetes mellitus type 2, irritable bowel syndrome (IBS), and urinary incontinence.
DB06210EltrombopagThrombopoietin receptor agonists are pharmaceutical agents that stimulate platelet production in the bone marrow. In this, they differ from the previously discussed agents that act by attempting to curtail platelet destruction.
DB06251DersalazineInvestigated for use/treatment in inflammatory bowel disease.
DB06276TanomastatInvestigated for use/treatment in pancreatic cancer, lung cancer, ovarian cancer, and osteoarthritis.
DB06288AmisulprideInvestigated for use/treatment in schizophrenia and schizoaffective disorders, mania in bipolar disorder, and depression.
DB06306OnalespibInvestigated for use/treatment in cancer/tumors (unspecified).
DB06334TucidinostatInvestigated for use/treatment in cancer/tumors (unspecified).
DB06403AmbrisentanAmbrisentan is indicated for treatment of idiopathic (‘primary’) pulmonary arterial hypertension (IPAH) and pulmonary arterial hypertension (PAH) associated with connective tissue disease in patients with WHO functional class II or III symptoms. In the United States of America, ambrisentan is also indicated in combination with tadalafil to reduce the risks of disease progression and hospitalization for worsening PAH, and to improve exercise ability.
DB06421DeclopramideInvestigated for use/treatment in colorectal cancer and inflammatory bowel disease.
DB06465FK-960Investigated for use/treatment in dementia, alzheimer's disease, schizophrenia and schizoaffective disorders, and memory loss.
DB06497AplavirocInvestigated for use/treatment in HIV infection.
DB06521ErtiprotafibInvestigated for use/treatment in diabetes mellitus type 2.
DB06533RagaglitazarInvestigated for use/treatment in diabetes mellitus type 2.
DB06536TesaglitazarInvestigated for use/treatment in diabetes mellitus type 2.
DB06578TonabersatInvestigated for use/treatment in migraine and cluster headaches.
DB06660SaredutantInvestigated for use/treatment in depression and anxiety disorders.
DB06666LixivaptanInvestigated for use/treatment in hyponatremia and congestive heart failure.
DB06736AceclofenacAceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
DB06799MethenamineFor prophylactic or suppressive treatment of frequently recurring urinary tract infections when long-term therapy is considered necessary. This drug is not used to treat infection and should only be used after appropriate eradication of infection with antimicrobial agents.
DB06802NepafenacFor the treatment of pain and inflammation associated with cataract surgery.
DB06807Phenyl aminosalicylateNot Available
DB06819Phenylbutyric acidAdjunctive therapy for the management of chronic urea cycle disorders due to deficiencies in carbamylphosphate (CPS), ornithine transcarbamylase (OTC), or argininosuccinic acid synthetase. it is indicated in all neonatal- onset efficiency presenting within the first 28 days of life. Also indicated in patients with late-onset, presenting after the first month of life with a history of hyperammonemic encephalopathy.
DB070693-Hydroxyhippuric acidNot Available
DB07477FelbinacNot Available
DB07615TranilastFor the treatment of bronchial asthma, keloid and hypertrophic scar, and allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
DB07767Ferulic acidNot Available
DB08427PREPHENIC ACIDNot Available
DB08437PuromycinNot Available
DB086362-HydroxybenzalpyruvateNot Available
DB08797SalicylamideNot Available
DB08810CinitaprideIt is indicated to treat gastrointestinal disorders associated with motility disturbances like gastroesophageal reflux disease (GERD), non-ulcer dyspepsia and delayed gastric emptying.
DB08814TriflusalTriflusal is indicated as prophylaxis of thromboembolic disorders.[L1185] It has been registered in Spain and in other countries of Europe, South America and South Korea for the prevention of Stroke and myocardial infarction.[T93]
DB08909Glycerol phenylbutyrateGlycerol phenylbutyrate is a nitrogen-binding agent for the chronic management of adult and pediatric patients ≥2 years of age with urea cycle disorders (UCDs) who cannot be managed by dietary protein restriction and/or amino acid supplementation alone.
DB08910PomalidomidePomalidomide is indicated for patients with multiple myeloma who have received at least two prior therapies including lenalidomide and bortezomib and have demonstrated disease progression on or within 60 days of completion of the last therapy.
DB08945Iotroxic acidNot Available
DB08947IopamidolNot Available
DB08948IodamideNot Available
DB08950IndoraminNot Available
DB08951IndoprofenNot Available
DB08976FloctafenineNot Available
DB08981FenbufenNot Available
DB08984EtofenamateNot Available
DB08989EtamivanNot Available
DB09018BromoprideBromopride in indicated in the treatment of nausea and vomiting, including PONV (post-operative nausea and vomiting), gastroesophageal reflux disease (GERD/GORD), as well as endoscopy preparation and radiographic studies of the GI tract.
DB09023BenactyzineNot Available
DB09085TetracaineThe combination lidocaine and tetracaine patch is indicated for local dermal analgesia for superficial dermatological procedures and superficial venous access. The combination lidocaine and tetracaine cream is intended to provide topical local analgesia for superficial dermatological procedures.
DB09086EugenolEugenol is not currently available in any FDA-approved drug products. There are a number of unapproved OTC products that advertise it for the use of toothache. Eugenol is is also commonly used in combination with zinc oxide in dental procedures for the cementation of temporary prostheses and the temporary restoration of teeth and cavities.
DB09088AmylocaineThe most common indication for the usage of amylocaine was spinal anesthesia [A32277].
DB09089TrimebutineIndicated for symptomatic treatment of irritable bowel syndrome (IBS) and treatment of postoperative paralytic ileus following abdominal surgery.
DB09096Benzoyl peroxideBenzoyl peroxide is indicated for the treatment of mild to moderate acne vulgaris and rosacea. Combined with other agents, it may be used in the treatment of more severe acne.
DB09133Iothalamic acidConray is indicated for use in excretory urography, cerebral angiography, peripheral arteriography, venography, arthrography, direct cholangiography, endoscopic retrograde cholangiopancreatography, contrast enhancement of computed tomographic brain images, cranial computerized angiotomography, intravenous digital subtraction angiography and arterial digital subtraction angiography. Conray may also be used for enhancement of computed tomographic scans performed for detection and evaluation of lesions in the liver, pancreas, kidneys, abdominal aorta, mediastinum, abdominal cavity and retroperitoneal space.
DB09134IoversolOptiray 350 is indicated in adults for peripheral and coronary arteriography and left ventriculography. Optiray 350 is also indicated for contrast enhanced computed tomographic imaging of the head and body, intravenous excretory urography, intravenous digital subtraction angiography and venography. Optiray 350 is indicated in children for angiocardiography. Optiray 320 is indicated in adults for angiography throughout the cardiovascular system. The uses include cerebral, coronary, peripheral, visceral and renal arteriography, venography, aortography, and left ventriculography. Optiray 320 is also indicated for contrast enhanced computed tomographic imaging of the head and body, and intravenous excretory urography. Optiray 320 is indicated in children for angiocardiography, contrast enhanced computed tomographic imaging of the head and body, and intravenous excretory urography. Optiray 300 is indicated for cerebral angiography and peripheral arteriography. Optiray 300 is also indicated for contrast enhanced computed tomographic imaging of the head and body, venography, and intravenous excretory urography. Optiray 240 is indicated for cerebral angiography and venography. Optiray 240 is also indicated for contrast enhanced computed tomographic imaging of the head and body and intravenous excretory urography.
DB09135IoxilanWhen administered intra-arterially, Ioxilan is indicated for the following diagnostic tests: cerebral arteriography (300 mgI/mL), coronary arteriography and left ventriculography (350 mgI/mL), visceral angiography(350 mgI/mL), aortography(350 mgI/mL), and peripheral arteriography(350 mgI/mL). When administered intravenously, Ioxilan is indicated for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body (300 and 350 mgI/mL).
DB09156IopromideIopromide, as the product Iovist, is indicated for use as an X-ray contrast agent in the following procedures: Intra-arterial digital subtraction angiography (IA-DSA) (150 mg I/mL) Cerebral arteriography and peripheral arteriography (300 mg I/mL) Coronary arteriography and left ventriculography, visceral angiography and aortography (370 mg I/mL) Peripheral venography (240 mg I/mL) Excretory urography (300 mg I/mL) Contrast computed tomography (CT) imaging of head and body (300 mg I/mL and 370 mg I/mL)
DB09212LoxoprofenLoxoprofen is non-steroidal anti-inflammatory medication (NSAID) indicated for pain and inflammation related to musculoskeletal and joint disorders [L1226]. In addition to its effects on pain, it is an antipyretic and anti-inflammatory medication [L1227].
DB09213DexibuprofenFor more information, refer to [ibuprofen].
DB09216Tolfenamic AcidIn the information for tolfenamic acid, it is stated that this drug, being an NSAID, is effective in treating the pain associated with the acute attack of migraines in adults.[L1293]
DB09269Phenylacetic acidFor use as adjunctive therapy for the treatment of acute hyperammonemia and associated encephalopathy in patients with deficiencies in enzymes of the urea cycle.
DB09285Morniflumate Morniflumate is indicated for the treatment of inflammatory conditions affecting the airways, ENT system, urogenital tract and bone and joint systems in adults. In Italy, morniflumate is also indicated for the treatment of pain associated with ear, nose, throat (ENT) and gastrointestinal inflammatory conditions in children. Morniflumate is a well established NSAID that has been in use for over three decades in Italy (particularly for the treatment of upper respiratory tract infections in children), France, Belgium, Austria, Switzerland, Spain and Portugal; it has a generally favorable tolerability profile.
DB09313Ioxaglic acidThis medicinal product is for diagnostic use only in adults and children as a low-osmolality medium [L1883], [A7924].
DB09320Procaine benzylpenicillinFor the treatment of a number of bacterial infections such as syphilis, anthrax, mouth infections, pneumonia and diphtheria.
DB09342PropoxycainePropoxycaine is a local anesthetic medication. It was used beginning in the 1950s during dental procedures [L1591]. It has been combined with procaine to accelerate its onset of action and provide longer-lasting anesthetic effect [L1592]. It was produced for use when amide local anesthetics were contraindicated due to allergy or when several amide anesthetics were unsuccessful [L1592].
DB09346Metrizoic acidFor use as a contrast medium [L1597].
DB09347Acetrizoic acidAcetrizoic acid indication was to be used as a contrast agent for X-ray. Some information indicates its nephrotropic property as one of the characteristics for the utilization of acetrizoic acid.[A32135] The X-ray imaging depends on the difference in tissue density which is provided by an X-ray attenuation between the area of interest and the surrounding tissue. The use of contrast agents will provoke a contrast enhancement or opacification and it will improve the differentiation of pathological processes from normal tissue.[T125]
DB09487IotrolanNot Available
DB09496OctinoxateAs an active ingredient in sunscreens and lip balms. Used for protection against damaging effects of sun rays.
DB09543Methyl salicylateOintments or liniments containing methyl salicylate are applied topically as counter irritant for relief of acute pain associated with lumbago,sciatica and rheumatic conditions. Local analgesics for human and veterinary medicine.
DB11062OctisalateIngredient in sunscreens for protection against damage effects of sun light, provides protection from sunburns, aging and skin cancer.
DB11064HomosalateAs ingredient in many sunscreen for protection against sunburn, skin aging and skin cancer.
DB11071Phenyl salicylatePain and fever [L2468].
DB11079Trolamine salicylateIndicated for the temporary relief of aches, and pains of muscles and joints associated with backache, lumbago, strains, bruises, sprains and arthritic or rheumatic pain, pain of tendons and ligaments [L1791].
DB11096MeradimateMeradimate is used as an active ingredient in sunscreens or as a sunblock factor in different products. It fits under the category of broad-spectrum absorbent agent. These characteristics are important to consider due to the fact that this kind of ingredients can either absorb or reflect UV radiation. It is also important to know the type of rays that cover. UVA rays are the responsible of causing sun damage and reaching deeper layers of the skin while UVB can only cause sunburn in the outer layer of the skin. When an agent is of broad spectrum, this means that this agent is capable of acting in both UVA and UVB rays.[L2749]
DB11148ButambenButamben was indicated for the treatment of chronic pain due to its long-duration effect.[A32663] It is also indicated as a surface anesthetic for skin a mucous membrane and for the relief of pain and pruritus associated with anorectal disorders.[L2445]
DB11207AmiloxateIndicated as an active sunscreen agent.
DB11229Padimate ANot Available
DB11282DiethyltoluamideDiethyltoluamide, or DEET, is an active ingredient that is predominantly indicated for as an insect repellant used to repel biting pests like mosquitoes and ticks [L2774]. Products containing DEET currently are available to the public in a variety of liquids, lotions, sprays, and impregnated materials like towelettes or roll-ons [L2774].
DB11285Ethyl ferulateNot Available
DB11323Glycol salicylateThis drug is only recommended for topical usages for the relief of muscular and rheumatic pain in human and animals [L2687].
DB11324Nonivamide Nonivamide is used as a topical analgesic and is also used as a flavoring ingredient [L2641], [A32884], [L2642].
DB11424LufenuronNot Available
DB11448PhosmetNot Available
DB11455RobenacoxibNot Available
DB11480ZoaleneNot Available
DB11502ButacaineNot Available
DB11552TricaineNot Available
DB11570Padimate OIndicated as an active UV-B filter to prevent photodamage.
DB11623CandoxatrilatNot Available
DB11671AZD-4877Not Available
DB11675MosaprideNot Available
DB11686IferanserinNot Available
DB11703AcalabrutinibAcalabrutinib is currently indicated for the treatment of adult patients with Mantle Cell Lymphoma (MCL) who have received at least one prior therapy [FDA Label].
DB11705IomeprolNot Available
DB11711NavarixinNot Available
DB11732LasmiditanNot Available
DB11763MomelotinibNot Available
DB11778DanusertibNot Available
DB11811ArhalofenateNot Available
DB11821DanegaptideNot Available
DB11830MocetinostatNot Available
DB11841EntinostatNot Available
DB11904FlumatinibNot Available
DB11941TasisulamNot Available
DB11986EntrectinibNot Available
DB12013AxelopranNot Available
DB12029Chlorogenic AcidNot Available
DB12113CE-224535Not Available
DB12150PelubiprofenNot Available
DB12206N-6022Not Available
DB12239BalicatibNot Available
DB12253GDC-0810Not Available
DB12272VidupiprantNot Available
DB12278PropiverineIndicated for symptomatic treatment of urinary incontinence and/or increased urinary frequency and urgency in patients with overactive bladder (OAB) [L2315]. Propiverine may also be used in patients with neurogenic bladder as a result of spinal cord injury [A32581].
DB12289DarexabanNot Available
DB12299BavisantNot Available
DB12323RadotinibRadotinib is indicated for the treatment of different types of cancer, most notably Philadelphia chromosome-positive (Ph+) chronic myeloid leukemia (CML) with resistance or intolerance of other Bcr-Abl tyrosine-kinase inhibitors, such as patients resistant or intolerant to imatinib.
DB12325IdasanutlinNot Available
DB12341LY-2456302Not Available
DB12364BetrixabanBetrixaban is indicated for prophylaxis of venous thromboembolism (VTE) in conditions of moderate to severe restricted mobility or in patients that qualify as in risk of VTE.
DB12407IobitridolNot Available
DB12408PF-03635659Not Available
DB12429CI-1040Not Available
DB12439IoforminolNot Available
DB12445NitroaspirinNot Available
DB12448LifibrolNot Available
DB12450Propyl GallateNot Available
DB12482AcotiamideNot Available
DB12518RacloprideNot Available
DB12524BI-671800Not Available
DB12545IndobufenNot Available
DB12556MK-5108Not Available
DB12563MK-0686Not Available
DB12576AZD-3043Not Available
DB12594AZD-9056Not Available
DB12632JNJ-41443532Not Available
DB12662NaveglitazarNot Available
DB12671BeloranibNot Available
DB12681SalirasibNot Available
DB12776E-6005Not Available
DB12798RelenoprideNot Available
DB12800CHF-6001Not Available
DB12805AtaciguatNot Available
DB12823TecarfarinNot Available
DB12850EtalocibNot Available
DB12853DA-6886Not Available
DB12887TazemetostatNot Available
DB12933RO-4987655Not Available
DB12934GranotapideNot Available
DB12981XL-888Not Available
DB13016LY-2300559Not Available
DB13025TiaprideTiapride is indicated for the treatment of a variety of neurological and psychiatric disorders including dyskinesia, alcohol withdrawal syndrome, negative symptoms of psychosis, and agitation and aggression in the elderly.
DB13027TucaresolNot Available
DB13039AminaphthoneNot Available
DB13086SCYX-7158Not Available
DB13115SaroglitazarNot Available
DB13167AlclofenacAlclofenac is indicated in rheumatology, in particular for the treatment of rheumatoid arthritis, ankylosing spondylitis and, as an analgesic, in painful arthritic pathologies.
DB13218Mandelic acidNot Available
DB13234PropanididNot Available
DB13265HexobendineNot Available
DB13273SultoprideNot Available
DB13327PicotamideNot Available
DB13336DimethylphthalateNot Available
DB13351PiperidolateNot Available
DB13380DifemerineNot Available
DB13428Iobenzamic acidNot Available
DB13444Ioxitalamic acidIoxitalamate in both of its available forms is indicated for exploration of the digestive tract by tomodensitometry or by regular gastroduodenal radiography. Its use is restrained to the cases in which the administration of barium sulfate is not recommended or contraindicated.[F55] The intravascular administration of ioxitalamate is contraindicated as it may present significant side effects.[F54]
DB13507PoldineNot Available
DB13509AloxiprinNot Available
DB13511CleboprideNot Available
DB13523VeraliprideNot Available
DB13538GuacetisalNot Available
DB13539Iodoxamic acidNot Available
DB13542BevoniumNot Available
DB13581RociverineNot Available
DB13612Carbaspirin calciumNot Available
DB13628Ethyl hydroxybenzoateNot Available
DB13657BenorilateNot Available
DB13701Ioglicic acidNot Available
DB13716DibutylphthalateNot Available
DB13722PirprofenNot Available
DB13731ButamirateNot Available
DB13741Ioglycamic acidNot Available
DB13755Iocarmic acidNot Available
DB13787TilidineNot Available
DB13855NifuroxazideNot Available
DB13860Imidazole salicylateNot Available
DB13861IopentolNot Available
DB13864Hemoglobin crosfumarilNot Available
DB13877IniparibNot Available
DB13909Bismuth subgallateThe most common medical purpose for which bismuth subgallate is currently and formally indicated for is the use as a non-prescription internal deodorant product for the purpose of deodorizing flatulence and stools [L2309, L2312, A32566]. Additionally, there are also various non-prescription (over the counter) bismuth subgallate based wound healing products as well as ongoing studies into whether or not the substance can be utilized as a legitimate hemostatic agent - usually for soft tissue surgery in otorhinolaryngology and/or dermatologic settings [A32567, A32568, A32569, A32570]. Moreover, in the past bismuth subgallate may have seen some use as a treatment for Helicobacter pylori infection [A32571]. In contrast, contemporary first-line therapies generally involve proton pump inhibitor and antibiotic combination therapies that generally achieve high rates of pathogen eradication, ease of administration, and patient compliance.
DB13931NetarsudilNetarsudil is indicated for the reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension [FDA Label].
DB14006Choline salicylateThe oral gel is indicated for the relief of pain and discomfort of common mouth ulcers, cold sores, denture sore spots, infant teething and mouth ulcers, and sore spots due to orthodontic devices in children [L2135].
DB14026Thiosalicylic acidNot Available
DB14084ButylparabenNot Available
DB14176BenzylparabenBenzylparaben is used in allergenic testing.
DB14177PropylparabenPropylparaben is used in allergenic testing.
DB14188IsoeugenolIsoeugenol is approved by the FDA for use within allergenic epicutaneous patch tests which are indicated for use as an aid in the diagnosis of allergic contact dermatitis (ACD) in persons 6 years of age and older.
DB14212MethylparabenNot Available
DB06422TicaloprideInvestigated for use/treatment in gastroesophageal reflux disease (GERD) and gastroparesis.
DB07338AcifluorfenNot Available
DB14720BrovanexineNot Available
DB02130Vanillic acidNot Available
DB03176KB-141Not Available
DB03884Phenylpyruvic acidNot Available
DB07101PD-0325901Not Available
DB07941PH-797804Not Available
DB12020TecovirimatSmallpox virus infection is an inhibitor of the orthopoxvirus VP37 envelope wrapping protein and is indicated for the treatment of human smallpox disease in adults and pediatric patients weighing at least 13 kg [FDA label].
DB01460DiethyltryptamineNot Available
DrugDrug NameTargetType
DB00209TrospiumMuscarinic acetylcholine receptor M1target
DB00209TrospiumCytochrome P450 2D6enzyme
DB00233Aminosalicylic Acid2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinasetarget
DB00233Aminosalicylic AcidGroup IIE secretory phospholipase A2target
DB00233Aminosalicylic AcidProstaglandin G/H synthase 2target
DB00233Aminosalicylic AcidArachidonate 5-lipoxygenasetarget
DB00233Aminosalicylic AcidInhibitor of nuclear factor kappa-B kinase subunit alphatarget
DB00233Aminosalicylic AcidMyeloperoxidaseenzyme
DB00302Tranexamic acidPlasminogentarget
DB00302Tranexamic acidSolute carrier family 15 member 2transporter
DB00310ChlorthalidoneSolute carrier family 12 member 1target
DB00310ChlorthalidoneSerum albumincarrier
DB00310ChlorthalidoneCarbonic anhydrase 1target
DB00345Aminohippuric acidSolute carrier family 22 member 2transporter
DB00345Aminohippuric acidSolute carrier family 22 member 5transporter
DB00345Aminohippuric acidSolute carrier family 22 member 6transporter
DB00345Aminohippuric acidSolute carrier family 22 member 8transporter
DB00345Aminohippuric acidCanalicular multispecific organic anion transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 4transporter
DB00345Aminohippuric acidSolute carrier family 22 member 11transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 3A1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1B1transporter
DB00345Aminohippuric acidMultidrug resistance-associated protein 1transporter
DB00345Aminohippuric acidSolute carrier organic anion transporter family member 1A2transporter
DB00345Aminohippuric acidMonocarboxylate transporter 1transporter
DB00345Aminohippuric acidSolute carrier family 22 member 7transporter
DB00348Nitisinone4-hydroxyphenylpyruvate dioxygenasetarget
DB00391SulpirideD(2) dopamine receptortarget
DB00391SulpirideD(3) dopamine receptortarget
DB00391SulpirideCarbonic anhydrase 2target
DB00391SulpirideCarbonic anhydrase 3target
DB00409RemoxiprideD(2) dopamine receptortarget
DB00409RemoxiprideD(4) dopamine receptortarget
DB00409Remoxipride5-hydroxytryptamine receptor 2Atarget
DB00409RemoxiprideSigma non-opioid intracellular receptor 1target
DB00409RemoxiprideD(3) dopamine receptortarget
DB00409RemoxiprideCytochrome P450 2D6enzyme
DB00422MethylphenidateSodium-dependent dopamine transportertarget
DB00422MethylphenidateSodium-dependent noradrenaline transportertarget
DB00422Methylphenidate5-hydroxytryptamine receptor 1Atarget
DB00480LenalidomideProstaglandin G/H synthase 2target
DB00480LenalidomideTumor necrosis factor ligand superfamily member 11target
DB00480LenalidomideProtein cereblontarget
DB00480LenalidomideMultidrug resistance protein 1transporter
DB00522BentiromideSerine protease hepsintarget
DB00573FenoprofenProstaglandin G/H synthase 1target
DB00573FenoprofenProstaglandin G/H synthase 2target
DB00573FenoprofenSerum albumincarrier
DB00573FenoprofenPeroxisome proliferator-activated receptor alphatarget
DB00573FenoprofenPeroxisome proliferator-activated receptor gammatarget
DB00586DiclofenacProstaglandin G/H synthase 1target
DB00586DiclofenacProstaglandin G/H synthase 2target
DB00586DiclofenacCytochrome P450 2C9enzyme
DB00586DiclofenacCytochrome P450 2C19enzyme
DB00586DiclofenacCytochrome P450 1A2enzyme
DB00586DiclofenacCytochrome P450 2C8enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 1-1enzyme
DB00586DiclofenacSerum albumincarrier
DB00586DiclofenacMultidrug resistance-associated protein 4transporter
DB00586DiclofenacMultidrug resistance protein 1transporter
DB00586DiclofenacMultidrug resistance-associated protein 1transporter
DB00586DiclofenacSolute carrier family 22 member 6transporter
DB00586DiclofenacSolute carrier family 22 member 8transporter
DB00586DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DB00586DiclofenacSolute carrier family 22 member 11transporter
DB00586DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DB00586DiclofenacProstaglandin G/H synthase 1enzyme
DB00586DiclofenacCytochrome P450 3A4enzyme
DB00586DiclofenacCytochrome P450 1A1enzyme
DB00586DiclofenacCytochrome P450 2B6enzyme
DB00586DiclofenacCytochrome P450 2C18enzyme
DB00586DiclofenacCytochrome P450 2E1enzyme
DB00586DiclofenacArachidonate 5-lipoxygenasetarget
DB00586DiclofenacSodium channel protein type 4 subunit alphatarget
DB00586DiclofenacAcid-sensing ion channel 1target
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 2target
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 3target
DB00586DiclofenacPhospholipase A2, membrane associatedtarget
DB00586DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DB00586DiclofenacBile salt export pumptransporter
DB00604Cisapride5-hydroxytryptamine receptor 4target
DB00604Cisapride5-hydroxytryptamine receptor 3Atarget
DB00604CisapridePotassium voltage-gated channel subfamily H member 2target
DB00604Cisapride5-hydroxytryptamine receptor 2Atarget
DB00604CisaprideCytochrome P450 3A4enzyme
DB00604CisaprideCytochrome P450 3A5enzyme
DB00604CisaprideCytochrome P450 3A7enzyme
DB00604CisaprideCytochrome P450 2A6enzyme
DB00604CisaprideCytochrome P450 2B6enzyme
DB00604CisaprideCytochrome P450 2C19enzyme
DB00604CisaprideCytochrome P450 2C8enzyme
DB00604CisaprideCytochrome P450 2C9enzyme
DB00604CisaprideCytochrome P450 2D6enzyme
DB00619ImatinibPlatelet-derived growth factor receptor betatarget
DB00619ImatinibTyrosine-protein kinase ABL1target
DB00619ImatinibMast/stem cell growth factor receptor Kittarget
DB00619ImatinibRET proto-oncogenetarget
DB00619ImatinibHigh affinity nerve growth factor receptortarget
DB00619ImatinibMacrophage colony-stimulating factor 1 receptortarget
DB00619ImatinibPlatelet-derived growth factor receptor alphatarget
DB00619ImatinibEpithelial discoidin domain-containing receptor 1target
DB00619ImatinibCytochrome P450 3A4enzyme
DB00619ImatinibBCR/ABL fusion protein isoform X9target
DB00619ImatinibCytochrome P450 1A2enzyme
DB00619ImatinibCytochrome P450 2D6enzyme
DB00619ImatinibCytochrome P450 2C9enzyme
DB00619ImatinibCytochrome P450 2C19enzyme
DB00619ImatinibCytochrome P450 3A5enzyme
DB00619ImatinibCytochrome P450 3A7enzyme
DB00619ImatinibSolute carrier family 22 member 1transporter
DB00619ImatinibMultidrug resistance protein 1transporter
DB00619ImatinibSolute carrier family 22 member 2transporter
DB00619ImatinibATP-binding cassette sub-family G member 2transporter
DB00619ImatinibATP-binding cassette sub-family A member 3transporter
DB00619ImatinibProstaglandin G/H synthase 1enzyme
DB00619ImatinibSerum albumincarrier
DB00619ImatinibAlpha-1-acid glycoprotein 1carrier
DB00619ImatinibBile salt export pumptransporter
DB00619ImatinibCytochrome P450 2C8enzyme
DB00626BacitracinInsulin-degrading enzymetarget
DB00626BacitracinC55-isoprenyl pyrophosphatetarget
DB00695FurosemideSolute carrier family 12 member 1target
DB00695FurosemideSerum albumincarrier
DB00695FurosemideSolute carrier family 22 member 6transporter
DB00695FurosemideSolute carrier family 22 member 5transporter
DB00695FurosemideSolute carrier family 22 member 8transporter
DB00695FurosemideCanalicular multispecific organic anion transporter 1transporter
DB00695FurosemideSolute carrier organic anion transporter family member 2A1transporter
DB00695FurosemideSolute carrier family 22 member 11transporter
DB00695Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00695FurosemideCarbonic anhydrase 2target
DB00695FurosemideUDP-glucuronosyltransferase 1-1enzyme
DB00695FurosemideThyroxine-binding globulincarrier
DB00721ProcaineSodium channel protein type 10 subunit alphatarget
DB00721ProcaineGlutamate receptor ionotropic, NMDA 3Atarget
DB00721Procaine5-hydroxytryptamine receptor 3Atarget
DB00721ProcaineSodium-dependent dopamine transportertarget
DB00721ProcaineNeuronal acetylcholine receptor subunit alpha-2target
DB00721ProcaineCalcium-activated potassium channeltarget
DB00721ProcainePhospholipase A2target
DB00721ProcaineMonoamine oxidasetarget
DB00771ClidiniumMuscarinic acetylcholine receptor M1target
DB00784Mefenamic acidProstaglandin G/H synthase 2target
DB00784Mefenamic acidProstaglandin G/H synthase 1target
DB00784Mefenamic acidCytochrome P450 2C9enzyme
DB00784Mefenamic acidCytochrome P450 2C8enzyme
DB00784Mefenamic acidSerum albumincarrier
DB00784Mefenamic acidUDP-glucuronosyltransferase 1-9enzyme
DB00804DicyclomineMuscarinic acetylcholine receptor M1target
DB00804DicyclomineMuscarinic acetylcholine receptor M2target
DB00804DicyclomineCytochrome P450 1A1enzyme
DB00807ProparacaineSodium channel protein type 10 subunit alphatarget
DB00861DiflunisalProstaglandin G/H synthase 1target
DB00861DiflunisalProstaglandin G/H synthase 2target
DB00861DiflunisalSerum albumincarrier
DB00861DiflunisalSolute carrier family 22 member 6transporter
DB00861DiflunisalUDP-glucuronosyltransferase 1-8enzyme
DB00861DiflunisalUDP-glucuronosyltransferase 1-9enzyme
DB00870SuprofenProstaglandin G/H synthase 1target
DB00870SuprofenProstaglandin G/H synthase 2target
DB00870SuprofenCytochrome P450 2C9enzyme
DB00870SuprofenUDP-glucuronosyltransferase 1-1enzyme
DB00870SuprofenUDP-glucuronosyltransferase 2B7enzyme
DB00887BumetanideSolute carrier family 12 member 1target
DB00887BumetanideCystic fibrosis transmembrane conductance regulatortarget
DB00887BumetanideSolute carrier family 12 member 2target
DB00887BumetanideSolute carrier family 12 member 4target
DB00887BumetanideSolute carrier family 12 member 5target
DB00887BumetanideSodium/bile acid cotransportertransporter
DB00887BumetanideSolute carrier family 22 member 6transporter
DB00887BumetanideSolute carrier family 22 member 8transporter
DB00887BumetanideSolute carrier family 22 member 11transporter
DB00887BumetanideSolute carrier family 22 member 7transporter
DB00887BumetanideSolute carrier organic anion transporter family member 1A2transporter
DB00887BumetanideProstaglandin G/H synthase 2enzyme
DB00892OxybuprocaineSodium channel protein type 10 subunit alphatarget
DB00936Salicylic acidSerum albumincarrier
DB00936Salicylic acidProstaglandin G/H synthase 1target
DB00936Salicylic acidProstaglandin G/H synthase 2target
DB00936Salicylic acidAldo-keto reductase family 1 member C1target
DB00936Salicylic acidSolute carrier family 22 member 6transporter
DB00936Salicylic acidSolute carrier family 22 member 10transporter
DB00936Salicylic acidSolute carrier family 22 member 8transporter
DB00936Salicylic acidSolute carrier family 22 member 11transporter
DB00936Salicylic acidSolute carrier organic anion transporter family member 2B1transporter
DB00936Salicylic acidMonocarboxylate transporter 1transporter
DB00936Salicylic acidSolute carrier family 22 member 7transporter
DB00936Salicylic acidCytochrome P450 2C9enzyme
DB00939Meclofenamic acidProstaglandin G/H synthase 1target
DB00939Meclofenamic acidProstaglandin G/H synthase 2target
DB00939Meclofenamic acidArachidonate 5-lipoxygenasetarget
DB00939Meclofenamic acidSolute carrier family 22 member 6transporter
DB00939Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
DB00939Meclofenamic acidThyroxine-binding globulincarrier
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidMultidrug resistance protein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidNuclear factor kappa b beta subunittarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DB00966TelmisartanType-1 angiotensin II receptortarget
DB00966TelmisartanPeroxisome proliferator-activated receptor gammatarget
DB00966TelmisartanMultidrug resistance protein 1transporter
DB00966TelmisartanCanalicular multispecific organic anion transporter 1transporter
DB00966TelmisartanATP-binding cassette sub-family G member 2transporter
DB00966TelmisartanCytochrome P450 2C19enzyme
DB00966TelmisartanBile salt export pumptransporter
DB00966TelmisartanUDP-glucuronosyltransferase 1-3enzyme
DB00979CyclopentolateMuscarinic acetylcholine receptor M1target
DB00996GabapentinAdenosine receptor A1target
DB00996GabapentinVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00996GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00996GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB00996GabapentinBranched-chain-amino-acid aminotransferase, cytosolicenzyme
DB00996GabapentinNMDA receptortarget
DB00996GabapentinGamma-aminobutyric acid type B receptor subunit 1target
DB00996GabapentinGamma-aminobutyric acid type B receptor subunit 2target
DB00996GabapentinCytochrome P450 3A4enzyme
DB01009KetoprofenProstaglandin G/H synthase 1target
DB01009KetoprofenProstaglandin G/H synthase 2target
DB01009KetoprofenC-X-C chemokine receptor type 1target
DB01009KetoprofenSerum albumincarrier
DB01009KetoprofenMultidrug resistance-associated protein 4transporter
DB01009KetoprofenSolute carrier organic anion transporter family member 1A2transporter
DB01009KetoprofenSolute carrier family 22 member 6transporter
DB01009KetoprofenSolute carrier family 22 member 8transporter
DB01009KetoprofenSolute carrier family 22 member 11transporter
DB01009KetoprofenSolute carrier family 22 member 7transporter
DB01009KetoprofenCytochrome P450 2C9enzyme
DB01009KetoprofenCytochrome P450 2C8enzyme
DB01009KetoprofenUDP-glucuronosyltransferase 1-1enzyme
DB01014BalsalazideProstaglandin G/H synthase 1target
DB01014BalsalazideProstaglandin G/H synthase 2target
DB01014BalsalazideArachidonate 5-lipoxygenasetarget
DB01014BalsalazidePeroxisome proliferator-activated receptor gammatarget
DB01014BalsalazideNADPH azoreductaseenzyme
DB01018GuanfacineAlpha-2A adrenergic receptortarget
DB01018GuanfacineCytochrome P450 2C19enzyme
DB01018GuanfacineCytochrome P450 3A4enzyme
DB01018GuanfacineAlpha-2B adrenergic receptortarget
DB01035ProcainamideSodium channel protein type 5 subunit alphatarget
DB01035ProcainamideDNA (cytosine-5)-methyltransferase 1target
DB01035ProcainamideCytochrome P450 2D6enzyme
DB01035ProcainamideSolute carrier family 22 member 2transporter
DB01035ProcainamideSolute carrier family 22 member 1transporter
DB01035ProcainamideSolute carrier family 22 member 3transporter
DB01035ProcainamideSolute carrier family 22 member 5transporter
DB01035ProcainamideSolute carrier family 22 member 4transporter
DB01035ProcainamidePotassium voltage-gated channel subfamily H member 2target
DB01035ProcainamideMultidrug and toxin extrusion protein 1transporter
DB01035ProcainamideMultidrug and toxin extrusion protein 2transporter
DB01041ThalidomideTumor necrosis factortarget
DB01041ThalidomideNuclear factor NF-kappa-B p105 subunittarget
DB01041ThalidomideProstaglandin G/H synthase 2target
DB01041ThalidomideCytochrome P450 2C19enzyme
DB01041ThalidomideCytochrome P450 1A1enzyme
DB01041ThalidomideCytochrome P450 2E1enzyme
DB01041ThalidomideCytochrome P450 2C9enzyme
DB01041ThalidomideProstaglandin G/H synthase 1enzyme
DB01041ThalidomideProstaglandin G/H synthase 2enzyme
DB01041ThalidomideCytochrome P450 3A5enzyme
DB01041ThalidomideFibroblast growth factor receptor 2target
DB01041ThalidomideProtein cereblontarget
DB01041ThalidomideNuclear factor kappa-light-chain-enhancer of activated B cellstarget
DB01041Thalidomidealpha1-acid glycoproteintarget
DB01050IbuprofenProstaglandin G/H synthase 1target
DB01050IbuprofenProstaglandin G/H synthase 2target
DB01050IbuprofenCytochrome P450 2C9enzyme
DB01050IbuprofenSerum albumincarrier
DB01050IbuprofenMultidrug resistance-associated protein 4transporter
DB01050IbuprofenMultidrug resistance-associated protein 1transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 1A2transporter
DB01050IbuprofenSolute carrier family 22 member 6transporter
DB01050IbuprofenSolute carrier family 22 member 8transporter
DB01050IbuprofenSolute carrier family 22 member 11transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 2B1transporter
DB01050IbuprofenMultidrug resistance protein 1transporter
DB01050IbuprofenUDP-glucuronosyltransferase 1-3enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 1-9enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B4enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B7enzyme
DB01050IbuprofenCytochrome P450 2C8enzyme
DB01050IbuprofenCytochrome P450 2C19enzyme
DB01050IbuprofenApoptosis regulator Bcl-2target
DB01050IbuprofenFatty acid-binding protein, intestinaltarget
DB01050IbuprofenPeroxisome proliferator-activated receptor gammatarget
DB01050IbuprofenCystic fibrosis transmembrane conductance regulatortarget
DB01050IbuprofenPeroxisome proliferator-activated receptor alphatarget
DB01050IbuprofenPlatelet glycoprotein Ib alpha chaintarget
DB01050IbuprofenProtein S100-A7target
DB01050IbuprofenAlpha-methylacyl-CoA racemaseenzyme
DB01062OxybutyninMuscarinic acetylcholine receptor M1target
DB01062OxybutyninMuscarinic acetylcholine receptor M2target
DB01062OxybutyninMuscarinic acetylcholine receptor M3target
DB01062OxybutyninCytochrome P450 3A4enzyme
DB01062OxybutyninCytochrome P450 2C8enzyme
DB01062OxybutyninCytochrome P450 2D6enzyme
DB01062OxybutyninCytochrome P450 3A5enzyme
DB01086BenzocaineSodium channel protein type 10 subunit alphatarget
DB01086BenzocaineMultidrug resistance protein 1transporter
DB01086BenzocaineLiver carboxylesterase 1enzyme
DB01161ChloroprocaineSodium channel protein type 10 subunit alphatarget
DB01161ChloroprocaineNeuronal acetylcholine receptor subunit alpha-10target
DB01161ChloroprocaineSodium-dependent dopamine transportertarget
DB01161ChloroprocaineGlutamate receptor ionotropic, NMDA 3Atarget
DB01161Chloroprocaine5-hydroxytryptamine receptor 3Atarget
DB01168ProcarbazineXanthine dehydrogenase/oxidaseenzyme
DB01168ProcarbazineCytochrome P450 1B1enzyme
DB01168ProcarbazineMonoamine oxidasetarget
DB01171MoclobemideAmine oxidase [flavin-containing] Atarget
DB01171MoclobemideCytochrome P450 2C19enzyme
DB01171MoclobemideCytochrome P450 2D6enzyme
DB01171MoclobemideAmine oxidase [flavin-containing] Aenzyme
DB01171MoclobemideAmine oxidase [flavin-containing] Benzyme
DB01171MoclobemideCytochrome P450 2C9enzyme
DB01171MoclobemideMonoamine oxidasetarget
DB01171MoclobemideAmine oxidase [flavin-containing] Btarget
DB01233MetoclopramideMuscarinic acetylcholine receptor M1target
DB01233MetoclopramideD(2) dopamine receptortarget
DB01233MetoclopramideCytochrome P450 2D6enzyme
DB01233Metoclopramide5-hydroxytryptamine receptor 4target
DB01233MetoclopramideCytochrome P450 11B1, mitochondrialenzyme
DB01233MetoclopramideCytochrome P450 11B2, mitochondrialenzyme
DB01233MetoclopramideSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01233Metoclopramide5-hydroxytryptamine receptor 3Atarget
DB01250OlsalazineInterferon gammatarget
DB01250OlsalazineThiopurine S-methyltransferasetarget
DB01283LumiracoxibProstaglandin G/H synthase 2target
DB01283LumiracoxibProstaglandin G/H synthase 1target
DB01283LumiracoxibCytochrome P450 2C9enzyme
DB01283LumiracoxibCytochrome P450 2C19enzyme
DB01283LumiracoxibUDP-glucuronosyltransferase 1-9enzyme
DB01283LumiracoxibCytochrome P450 1A2enzyme
DB01294Bismuth subsalicylateSerum albumincarrier
DB01294Bismuth subsalicylateSerotransferrincarrier
DB01393BezafibratePeroxisome proliferator-activated receptor alphatarget
DB01393BezafibrateSolute carrier organic anion transporter family member 1B1transporter
DB01393BezafibratePeroxisome proliferator-activated receptor deltatarget
DB01393BezafibratePeroxisome proliferator-activated receptor gammatarget
DB01393BezafibrateCytochrome P450 1A1enzyme
DB01393BezafibrateCytochrome P450 2C8enzyme
DB01393BezafibrateCytochrome P450 3A4enzyme
DB01393BezafibrateNuclear receptor subfamily 1 group I member 2target
DB01393BezafibrateRetinoic acid receptor RXR-alphatarget
DB01393BezafibrateRetinoic acid receptor RXR-betatarget
DB01393BezafibrateRetinoic acid receptor RXR-gammatarget
DB01397Magnesium salicylateSerum albumincarrier
DB01397Magnesium salicylateProstaglandin G/H synthase 1target
DB01397Magnesium salicylateProstaglandin G/H synthase 2target
DB01399SalsalateProstaglandin G/H synthase 1target
DB01399SalsalateProstaglandin G/H synthase 2target
DB01401Choline magnesium trisalicylateProstaglandin G/H synthase 1target
DB01401Choline magnesium trisalicylateProstaglandin G/H synthase 2target
DB01609DeferasiroxCytochrome P450 3A4enzyme
DB01609DeferasiroxUDP-glucuronosyltransferase 1-1enzyme
DB01609DeferasiroxUDP-glucuronosyltransferase 1-3enzyme
DB01609DeferasiroxUDP-glucuronosyltransferase 1-9enzyme
DB01609DeferasiroxCytochrome P450 2C8enzyme
DB01609DeferasiroxCytochrome P450 1A2enzyme
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01656RoflumilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DB01656RoflumilastCytochrome P450 3A4enzyme
DB01681Benzene Hexacarboxylic AcidPhosphoglycerate mutase 2target
DB01791PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB01791PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB01791PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Ctarget
DB01791PiclamilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB018803,4-Dihydroxycinnamic AcidPhotoactive yellow proteintarget
DB018803,4-Dihydroxycinnamic AcidHistidine ammonia-lyasetarget
DB018803,4-Dihydroxycinnamic AcidMacrophage migration inhibitory factortarget
DB020243-phenylpropionic acidAspartate aminotransferasetarget
DB020243-phenylpropionic acidAromatic-amino-acid aminotransferasetarget
DB020243-phenylpropionic acidAminotransferasetarget
DB02054GabaculineOrnithine aminotransferase, mitochondrialtarget
DB02054GabaculineGlutamate-1-semialdehyde 2,1-aminomutasetarget
DB02251O-SuccinylbenzoateN-acylamino acid racemasetarget
DB02251O-Succinylbenzoateo-succinylbenzoate synthasetarget
DB02251O-SuccinylbenzoateO-succinylbenzoate-CoA synthasetarget
DB02266Flufenamic AcidAldo-keto reductase family 1 member C3target
DB02266Flufenamic AcidTransthyretincarrier
DB02266Flufenamic AcidProstaglandin G/H synthase 2target
DB02266Flufenamic AcidProstaglandin G/H synthase 1target
DB02266Flufenamic AcidSolute carrier family 22 member 6transporter
DB02266Flufenamic AcidAndrogen receptortarget
DB02266Flufenamic AcidPeroxisome proliferator-activated receptor alphatarget
DB02266Flufenamic AcidPeroxisome proliferator-activated receptor gammatarget
DB02279Benzoylformic AcidHydroxyacid oxidase 1target
DB02362Aminobenzoic acidp-hydroxybenzoate hydroxylasetarget
DB02362Aminobenzoic acidp-hydroxybenzoate hydroxylasetarget
DB02715Compound 18Estrogen receptor alphatarget
DB02746Phthalic AcidNicotinate-nucleotide pyrophosphorylase [carboxylating]target
DB02746Phthalic AcidSolute carrier organic anion transporter family member 2B1transporter
DB02746Phthalic AcidEstrogen receptor alphatarget
DB02746Phthalic AcidProgesterone receptortarget
DB02746Phthalic AcidEstrogen receptor betatarget
DB02746Phthalic AcidPeroxisome proliferator-activated receptor alphatarget
DB02746Phthalic AcidPeroxisome proliferator-activated receptor deltatarget
DB02746Phthalic AcidPeroxisome proliferator-activated receptor gammatarget
DB02746Phthalic AcidRetinoic acid receptor RXR-alphatarget
DB02746Phthalic AcidRetinoic acid receptor RXR-betatarget
DB02746Phthalic AcidRetinoic acid receptor RXR-gammatarget
DB02749Pyromellitic AcidFumarate hydratase class IItarget
DB02793Isochorismic AcidPhenazine biosynthesis protein PhzDtarget
DB02795P-Anisic AcidGroup IIE secretory phospholipase A2target
DB02795P-Anisic AcidPhospholipase A2target
DB028392,4-Dihydroxybenzoic Acidp-hydroxybenzoate hydroxylasetarget
DB028392,4-Dihydroxybenzoic Acidp-hydroxybenzoate hydroxylasetarget
DB02877Arotinoid acidRetinoic acid receptor betatarget
DB030733-MethoxybenzamidePoly [ADP-ribose] polymerase 1target
DB03588Diphenylacetic AcidCathepsin Btarget
DB036443-hydroxyanthranilic acidTrans-2,3-dihydro-3-hydroxyanthranilate isomerasetarget
DB03728p-Chlorobenzoic acid4-chlorobenzoyl CoA ligasetarget
DB03793Benzoic AcidPeroxiredoxin-5, mitochondrialtarget
DB03793Benzoic AcidHeat-labile enterotoxin B chaintarget
DB03793Benzoic AcidCocaine esterasetarget
DB03793Benzoic AcidHTH-type transcriptional regulator MalTtarget
DB03793Benzoic AcidTautomerase PptAtarget
DB03793Benzoic AcidD-amino-acid oxidasetarget
DB03793Benzoic AcidRibonuclease UK114target
DB03793Benzoic AcidChlorocatechol 1,2-dioxygenasetarget
DB03793Benzoic AcidRas-related protein Rab-9Atarget
DB03793Benzoic AcidHydrogen peroxide-inducible genes activatortarget
DB03793Benzoic Acid2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolasetarget
DB03793Benzoic AcidNon-heme chloroperoxidasetarget
DB03793Benzoic AcidOxygen-insensitive NAD(P)H nitroreductasetarget
DB03793Benzoic AcidHydroxyquinol 1,2-dioxygenasetarget
DB03793Benzoic AcidReplication proteintarget
DB03793Benzoic AcidSolute carrier organic anion transporter family member 2B1transporter
DB03793Benzoic AcidSolute carrier family 22 member 8transporter
DB03793Benzoic AcidMonocarboxylate transporter 1transporter
DB03793Benzoic AcidSolute carrier family 15 member 1target
DB03849CilomilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB03849CilomilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB038683-Dehydroquinic Acid3-dehydroquinate dehydratasetarget
DB04066para-Coumaric AcidPhotoactive yellow proteintarget
DB04066para-Coumaric AcidPPHtarget
DB04066para-Coumaric AcidProstaglandin reductase 1target
DB04066para-Coumaric AcidHistidine ammonia-lyasetarget
DB04098BalanolcAMP-dependent protein kinase catalytic subunit alphatarget
DB04166Anthranilic acidL-amino-acid oxidasetarget
DB04166Anthranilic acidD-amino-acid oxidasetarget
DB04328Shikimate-3-Phosphate3-phosphoshikimate 1-carboxyvinyltransferasetarget
DB04328Shikimate-3-Phosphate3-phosphoshikimate 1-carboxyvinyltransferasetarget
DB043473-Dehydroshikimate3-dehydroquinate dehydratasetarget
DB043473-Dehydroshikimate3-dehydroquinate dehydratasetarget
DB04552Niflumic acidPhospholipase A2target
DB04552Niflumic acidChloride channel protein ClC-Katarget
DB04552Niflumic acidMonocarboxylate transporter 2transporter
DB04552Niflumic acidMonocarboxylate transporter 1transporter
DB04552Niflumic acidProstaglandin G/H synthase 2target
DB04552Niflumic acidProstaglandin G/H synthase 1target
DB04552Niflumic acidCytosolic phospholipase A2target
DB04552Niflumic acidUDP-glucuronosyltransferase 1-9target
DB04552Niflumic acidUDP-glucuronosyltransferase 1-9enzyme
DB04711IodipamideSerum albumincarrier
DB04838CyclandelateVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB04838CyclandelateLiver carboxylesterase 1target
DB04838CyclandelateCytochrome P450 3A4enzyme
DB04843MepenzolateMuscarinic acetylcholine receptor M1target
DB04843MepenzolateMuscarinic acetylcholine receptor M3target
DB04883DarusentanEndothelin-1 receptortarget
DB04917Renzapride5-hydroxytryptamine receptor 3Atarget
DB04917Renzapride5-hydroxytryptamine receptor 4target
DB04924ItoprideD(2) dopamine receptortarget
DB04942TamibaroteneRetinoic acid receptor alphatarget
DB04942TamibaroteneRetinoic acid receptor betatarget
DB04942TamibaroteneCellular retinoic acid-binding protein 1carrier
DB05009ApadenosonAdenosine receptor A2atarget
DB05050ADL5859Delta-type opioid receptortarget
DB05130INCB3284C-C chemokine receptor type 2target
DB05191Atl146eAdenosine receptor A2atarget
DB05227APD7915-hydroxytryptamine receptor 2Atarget
DB05255RonacaleretExtracellular calcium-sensing receptortarget
DB05255RonacaleretProbable G-protein coupled receptor 110target
DB05303OMS-103HPTumor necrosis factortarget
DB05303OMS-103HPInterleukin-1 receptor type 1target
DB05507VX-765Interleukin-1 betatarget
DB05542Naronapride5-hydroxytryptamine receptor 4target
DB05676ApremilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Dtarget
DB05676ApremilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Atarget
DB05676ApremilastcAMP-specific 3',5'-cyclic phosphodiesterase 4Btarget
DB05676ApremilastTumor necrosis factortarget
DB05676ApremilastInterferon gammatarget
DB05676ApremilastNitric oxide synthase, endothelialtarget
DB05676ApremilastCytochrome P450 3A4enzyme
DB05678SLx-4090Microsomal triglyceride transfer protein large subunittarget
DB06070SNX-5422Heat shock protein HSP 90-alphatarget
DB06070SNX-5422Heat shock protein HSP 90-betatarget
DB06082PX-478Hypoxia-inducible factor 1-alphatarget
DB06190SolabegronBeta-3 adrenergic receptortarget
DB06210EltrombopagThrombopoietin receptortarget
DB06210EltrombopagCytochrome P450 2C8enzyme
DB06210EltrombopagCytochrome P450 1A2enzyme
DB06210EltrombopagUDP-glucuronosyltransferase 1-1enzyme
DB06210EltrombopagUDP-glucuronosyltransferase 1-3enzyme
DB06210EltrombopagSolute carrier organic anion transporter family member 1B1transporter
DB06210EltrombopagATP-binding cassette sub-family G member 2transporter
DB06210EltrombopagUDP-glucuronosyltransferase 1-9enzyme
DB06288AmisulprideD(2) dopamine receptortarget
DB06288AmisulprideD(3) dopamine receptortarget
DB06288Amisulpride5-hydroxytryptamine receptor 7target
DB06288Amisulpride5-hydroxytryptamine receptor 2Atarget
DB06403AmbrisentanEndothelin B receptortarget
DB06403AmbrisentanEndothelin-1 receptortarget
DB06403AmbrisentanCytochrome P450 2C19enzyme
DB06403AmbrisentanCytochrome P450 3A4enzyme
DB06403AmbrisentanUDP-glucuronosyltransferase 1-9enzyme
DB06403AmbrisentanUDP-glucuronosyltransferase 1-3enzyme
DB06403AmbrisentanUDP-glucuronosyltransferase 2B7enzyme
DB06403AmbrisentanMultidrug resistance protein 1transporter
DB06403AmbrisentanSolute carrier organic anion transporter family member 1B1transporter
DB06403AmbrisentanSolute carrier organic anion transporter family member 1B3transporter
DB06403AmbrisentanCytochrome P450 3A5enzyme
DB06421DeclopramideDNA topoisomerase 2-alphatarget
DB06421DeclopramideDNA topoisomerase 2-betatarget
DB06497AplavirocC-C chemokine receptor type 5target
DB06521ErtiprotafibTyrosine-protein phosphatase non-receptor type 1target
DB06521ErtiprotafibInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB06521ErtiprotafibPeroxisome proliferator-activated receptor alphatarget
DB06521ErtiprotafibPeroxisome proliferator-activated receptor gammatarget
DB06533RagaglitazarPeroxisome proliferator-activated receptor alphatarget
DB06533RagaglitazarPeroxisome proliferator-activated receptor gammatarget
DB06536TesaglitazarPeroxisome proliferator-activated receptor alphatarget
DB06536TesaglitazarPeroxisome proliferator-activated receptor gammatarget
DB06660SaredutantSubstance-K receptortarget
DB06736AceclofenacCytochrome P450 2C9enzyme
DB06736AceclofenacProstaglandin G/H synthase 2target
DB06736AceclofenacProstaglandin G/H synthase 1target
DB06802NepafenacProstaglandin G/H synthase 1target
DB06802NepafenacProstaglandin G/H synthase 2target
DB06819Phenylbutyric acidAromatic-amino-acid aminotransferasetarget
DB06819Phenylbutyric acidThermolysintarget
DB06819Phenylbutyric acidCytochrome P450 2D6enzyme
DB070693-Hydroxyhippuric acidKynureninasetarget
DB07477FelbinacCathepsin L1target
DB07615TranilastHematopoietic prostaglandin D synthasetarget
DB07615TranilastCytochrome P450 3A4enzyme
DB07615TranilastCytochrome P450 2C9enzyme
DB07767Ferulic acidEndo-1,4-beta-xylanase Ytarget
DB07767Ferulic acidEndo-1,4-beta-xylanase Ztarget
DB07767Ferulic acidEst1etarget
DB07767Ferulic acidO-methyltransferasetarget
DB08407PLATENSIMYCIN3-oxoacyl-[acyl-carrier-protein] synthase 2target
DB08427PREPHENIC ACIDChorismate mutase AroHtarget
DB08437Puromycin60S ribosomal protein L10-liketarget
DB08437Puromycin60S ribosomal protein L13atarget
DB08437Puromycin60S ribosomal protein L23target
DB08437Puromycin60S ribosomal protein L15target
DB08437Puromycin60S ribosomal protein L19target
DB08437Puromycin60S ribosomal protein L23atarget
DB08437PuromycinProbable ribosome biogenesis protein RLP24target
DB08437Puromycin60S ribosomal protein L26-like 1target
DB08437Puromycin60S ribosomal protein L8target
DB08437Puromycin60S ribosomal protein L37target
DB08437Puromycin60S ribosomal protein L3target
DB08437Puromycin60S ribosomal protein L11target
DB08437PuromycinLeucyl/phenylalanyl-tRNA--protein transferasetarget
DB086362-Hydroxybenzalpyruvate2-hydroxychromene-2-carboxylate isomerasetarget
DB087484-(DIMETHYLAMINO)BENZOIC ACIDReplicase polyprotein 1abtarget
DB087484-(DIMETHYLAMINO)BENZOIC ACIDOrf1a polyproteintarget
DB08810Cinitapride5-hydroxytryptamine receptor 1Atarget
DB08810Cinitapride5-hydroxytryptamine receptor 4target
DB08810Cinitapride5-hydroxytryptamine receptor 2Atarget
DB08814TriflusalProstaglandin G/H synthase 1target
DB08814TriflusalNuclear factor NF-kappa-B p105 subunittarget
DB08814TriflusalNitric oxide synthase, inducibletarget
DB08814TriflusalcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10Atarget
DB08814TriflusalSerum albumincarrier
DB08909Glycerol phenylbutyratePancreatic triacylglycerol lipaseenzyme
DB08909Glycerol phenylbutyrateCytochrome P450 3A4enzyme
DB08909Glycerol phenylbutyrateCytochrome P450 2D6enzyme
DB08910PomalidomideCytochrome P450 1A2enzyme
DB08910PomalidomideCytochrome P450 3A4enzyme
DB08910PomalidomideMultidrug resistance protein 1transporter
DB08910PomalidomideProtein cereblontarget
DB08910PomalidomideTumor necrosis factortarget
DB08910PomalidomideProstaglandin G/H synthase 2target
DB08950IndoraminAlpha-1A adrenergic receptortarget
DB08984EtofenamateThyroxine-binding globulincarrier
DB09018BromoprideD(2) dopamine receptortarget
DB09085TetracaineRyanodine receptor 1target
DB09085TetracaineRyanodine receptor 2target
DB09085TetracaineVoltage gated sodium channeltarget
DB09086EugenolEstrogen receptor alphatarget
DB09086EugenolEstrogen receptor betatarget
DB09086EugenolAndrogen receptortarget
DB09086EugenolTransient receptor potential cation channel subfamily V member 3target
DB09088AmylocaineVoltage gated sodium channeltarget
DB09089TrimebutineMu-type opioid receptortarget
DB09089TrimebutineVoltage-dependent L-type calcium channeltarget
DB09089TrimebutineCalcium-activated potassium channeltarget
DB09089TrimebutineVoltage-dependent T-type calcium channeltarget
DB09089TrimebutineMuscarinic acetylcholine receptor M1target
DB09089TrimebutineMuscarinic acetylcholine receptor M2target
DB09089TrimebutineMuscarinic acetylcholine receptor M3target
DB09089TrimebutineMuscarinic acetylcholine receptor M4target
DB09089TrimebutineCytochrome P450 3A4enzyme
DB09212LoxoprofenProstaglandin G/H synthase 2target
DB09212LoxoprofenProstaglandin G/H synthase 1target
DB09212LoxoprofenProstaglandin G/H synthase 1enzyme
DB09212LoxoprofenProstaglandin G/H synthase 2enzyme
DB09213DexibuprofenProstaglandin G/H synthase 1target
DB09213DexibuprofenProstaglandin G/H synthase 2target
DB09213DexibuprofenApoptosis regulator Bcl-2target
DB09213DexibuprofenTissue-type plasminogen activatortarget
DB09213DexibuprofenFatty acid-binding protein, intestinaltarget
DB09213DexibuprofenPeroxisome proliferator-activated receptor gammatarget
DB09213DexibuprofenCystic fibrosis transmembrane conductance regulatortarget
DB09213DexibuprofenCytochrome P450 2C9enzyme
DB09213DexibuprofenSerum albumincarrier
DB09213DexibuprofenMultidrug resistance-associated protein 4transporter
DB09213DexibuprofenMultidrug resistance-associated protein 1transporter
DB09213DexibuprofenSolute carrier organic anion transporter family member 1A2transporter
DB09213DexibuprofenSolute carrier family 22 member 6transporter
DB09213DexibuprofenSolute carrier family 22 member 8transporter
DB09213DexibuprofenSolute carrier family 22 member 11transporter
DB09213DexibuprofenSolute carrier organic anion transporter family member 2B1transporter
DB09213DexibuprofenMultidrug resistance protein 1transporter
DB09213DexibuprofenUDP-glucuronosyltransferase 1-1enzyme
DB09213DexibuprofenUDP-glucuronosyltransferase 1-3enzyme
DB09213DexibuprofenUDP-glucuronosyltransferase 1-9enzyme
DB09213DexibuprofenUDP-glucuronosyltransferase 2B4enzyme
DB09213DexibuprofenUDP-glucuronosyltransferase 2B7enzyme
DB09213DexibuprofenCytochrome P450 2C8enzyme
DB09213DexibuprofenCytochrome P450 2C19enzyme
DB09213DexibuprofenSolute carrier family 15 member 1target
DB09213DexibuprofenPeroxisome proliferator-activated receptor alphatarget
DB09213DexibuprofenPlatelet glycoprotein Ib alpha chaintarget
DB09213DexibuprofenProtein S100-A7target
DB09213DexibuprofenAlpha-methylacyl-CoA racemaseenzyme
DB09216Tolfenamic AcidProstaglandin G/H synthase 1target
DB09216Tolfenamic AcidProstaglandin G/H synthase 2target
DB09216Tolfenamic AcidCytochrome P450 3A4enzyme
DB09269Phenylacetic acidLiver carboxylesterase 1enzyme
DB09285MorniflumateArachidonate 5-lipoxygenasetarget
DB09285MorniflumateProstaglandin G/H synthase 2target
DB09285MorniflumateArachidonate 5-lipoxygenaseenzyme
DB09285MorniflumateProstaglandin G/H synthase 2enzyme
DB09285MorniflumateLeukotriene B4 receptor 1target
DB09285MorniflumateThromboxane A2 receptortarget
DB09285MorniflumateUDP-glucuronosyltransferase 1A9enzyme
DB09342PropoxycaineVoltage gated sodium channeltarget
DB09342PropoxycaineLiver carboxylesterase 1enzyme
DB09347Acetrizoic acidSerum albumincarrier
DB11064HomosalateProgesterone receptortarget
DB11064HomosalateAndrogen receptortarget
DB11064HomosalateEstrogen receptor alphatarget
DB11071Phenyl salicylateProstaglandin G/H synthase 1target
DB11071Phenyl salicylateProstaglandin G/H synthase 2target
DB11079Trolamine salicylateProstaglandin G/H synthase 1target
DB11079Trolamine salicylateProstaglandin G/H synthase 2target
DB11148ButambenVoltage-dependent calcium channeltarget
DB11148ButambenVoltage gated sodium channeltarget
DB11148ButambenAlpha-1-acid glycoprotein 1carrier
DB11148ButambenSerum albumincarrier
DB11148ButambenATP-sensitive potassium channeltarget
DB11323Glycol salicylateProstaglandin G/H synthase 1target
DB11323Glycol salicylateProstaglandin G/H synthase 2target
DB11324NonivamideTransient receptor potential cation channel subfamily V member 1target
DB11455RobenacoxibCyclooxygenase 2target
DB11703AcalabrutinibTyrosine-protein kinase BTKtarget
DB11703AcalabrutinibCytochrome P450 3A4enzyme
DB11703AcalabrutinibCytochrome P450 3A5enzyme
DB11811ArhalofenatePeroxisome proliferator-activated receptor gammatarget
DB11830MocetinostatHistone deacetylase 1target
DB11830MocetinostatHistone deacetylase 3target
DB11830MocetinostatHistone deacetylase 2target
DB12278PropiverineMuscarinic acetylcholine receptor M1target
DB12278PropiverineMuscarinic acetylcholine receptor M2target
DB12278PropiverineMuscarinic acetylcholine receptor M3target
DB12278PropiverineMuscarinic acetylcholine receptor M4target
DB12278PropiverineMuscarinic acetylcholine receptor M5target
DB12278PropiverineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB12278PropiverineAlpha-1A adrenergic receptortarget
DB12278PropiverineCytochrome P450 3A4enzyme
DB12278PropiverineDimethylaniline monooxygenase [N-oxide-forming] 1enzyme
DB12278PropiverineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB12278PropiverineCYP2B proteinenzyme
DB12323RadotinibTyrosine-protein kinase ABL1target
DB12364BetrixabanMultidrug resistance protein 1transporter
DB12364BetrixabanCoagulation factor Xtarget
DB12364BetrixabanPotassium voltage-gated channel subfamily H member 2transporter
DB12445NitroaspirinProstaglandin G/H synthase 1target
DB12450Propyl GallateEstrogen receptor alphatarget
DB12518RacloprideD(2) dopamine receptortarget
DB12662NaveglitazarPeroxisome proliferator-activated receptor gammatarget
DB12887TazemetostatHistone-lysine N-methyltransferase EZH2target
DB13025TiaprideD(2) dopamine receptortarget
DB13025TiaprideD(3) dopamine receptortarget
DB13025TiaprideSerotonin Receptorstarget
DB13025TiaprideAlpha-1 adrenergic receptorstarget
DB13025TiaprideAlpha-2 adrenergic receptorstarget
DB13167AlclofenacProstaglandin G/H synthase 2target
DB13581RociverineMuscarinic acetylcholine receptor M1target
DB13581RociverineMuscarinic acetylcholine receptor M2target
DB13581RociverineMuscarinic acetylcholine receptor M3target
DB13581RociverineMuscarinic acetylcholine receptor M4target
DB13581RociverineMuscarinic acetylcholine receptor M5target
DB13877IniparibPoly [ADP-ribose] polymerase 1target
DB13909Bismuth subgallateSerum albumincarrier
DB13931NetarsudilRho-associated protein kinase 1target
DB13931NetarsudilRho-associated protein kinase 2target
DB13931Netarsudilsolute carrier family 6 member 2target
DB14006Choline salicylateCholine-phosphate cytidylyltransferase Btarget
DB14006Choline salicylateAcetylcholinesterasetarget
DB14006Choline salicylateCholine-phosphate cytidylyltransferase Atarget
DB14006Choline salicylatePhospholipase D2target
DB14006Choline salicylateCholinesterasetarget
DB14006Choline salicylatePhospholipase D1target
DB14006Choline salicylatePhosphoethanolamine/phosphocholine phosphatasetarget
DB14006Choline salicylateSolute carrier family 22 member 2transporter
DB14006Choline salicylateSolute carrier family 22 member 1transporter
DB14006Choline salicylateSolute carrier family 22 member 3transporter
DB14006Choline salicylateSolute carrier family 22 member 5transporter
DB14006Choline salicylateSolute carrier family 22 member 4transporter
DB14006Choline salicylateCholine/ethanolaminephosphotransferase 1enzyme
DB14006Choline salicylateCholine transporter-like protein 1transporter
DB14006Choline salicylateCholine transporter-like protein 4transporter
DB14006Choline salicylateCholine transporter-like protein 2transporter
DB14006Choline salicylateCholine transporter-like protein 3transporter
DB14006Choline salicylateCholine/ethanolamine kinaseenzyme
DB14006Choline salicylateCholine O-acetyltransferaseenzyme
DB14006Choline salicylateCholine kinase alphaenzyme
DB14006Choline salicylateCholine dehydrogenase, mitochondrialenzyme
DB14006Choline salicylateHigh affinity choline transporter 1transporter
DB14006Choline salicylateNeuronal acetylcholine receptor subunit alpha-7target
DB06422Ticalopride5-hydroxytryptamine receptor 4target
DB06422Ticalopride5-hydroxytryptamine receptor 3Atarget
DB07338AcifluorfenProtoporphyrinogen oxidasetarget
DB07338AcifluorfenProtoporphyrinogen oxidasetarget
DB02130Vanillic acidChorismate--pyruvate lyasetarget
DB03176KB-141Thyroid hormone receptor betatarget
DB03176KB-141Thyroid hormone receptor alphatarget
DB03884Phenylpyruvic acidMonocarboxylate transporter 4transporter
DB03884Phenylpyruvic acidL-phenylalanine dehydrogenasetarget
DB03884Phenylpyruvic acidHydroxyacid oxidase 1target
DB03884Phenylpyruvic acidIndole-3-pyruvate decarboxylasetarget
DB03884Phenylpyruvic acidPutative uncharacterized proteintarget
DB03884Phenylpyruvic acidBacilysin biosynthesis protein BacBtarget
DB03884Phenylpyruvic acidProbable chorismate mutasetarget
DB07101PD-0325901Dual specificity mitogen-activated protein kinase kinase 1target
DB07941PH-797804Mitogen-activated protein kinase 14target
DB12020TecovirimatEnvelope protein F13target
DB12020TecovirimatUDP-glucuronosyltransferase 1-1enzyme
DB12020TecovirimatUDP-glucuronosyltransferase 1-4enzyme