Acetanilides

Name
Acetanilides
Accession Number
DBCAT000598
Description

Compounds based on N-phenylacetamide, that are similar in structure to 2-PHENYLACETAMIDES. They are precursors of many other compounds. They were formerly used as ANALGESICS and ANTIPYRETICS, but often caused lethal METHEMOGLOBINEMIA.

Drugs
DrugDrug Description
PhenacetinUsed principally as an analgesic.
EtidocaineEtidocaine is marketed under the name Duranest. It is an injectable local anesthetic during surgery, labor, and delivery. Etidocaine has a long duration of activity, but has the main disadvantage...
PractololUsed in the emergency treatment of cardiac arrhythmias.
Inosine pranobexA medication used to treat subacute sclerosing panencephalitis.
NCX 701Investigated for use/treatment in pain (acute or chronic).
PropacetamolPropacetamol is a paracetamol prodrug of intravenous administration used to control fever and pain of perioperative period in multimodal analgesia therapy.
PilsicainidePilsicainide has been investigated for the treatment of Paroxysmal Atrial Fibrillation.
Drugs & Drug Targets
DrugTargetType
PhenacetinProstaglandin G/H synthase 1target
PhenacetinCytochrome P450 1A2enzyme
PhenacetinCytochrome P450 2D6enzyme
PhenacetinSolute carrier family 22 member 6transporter
PhenacetinCytochrome P450 1A1enzyme
PhenacetinCytochrome P450 2A13enzyme
PhenacetinCytochrome P450 2A6enzyme
PhenacetinCytochrome P450 2C19enzyme
PhenacetinCytochrome P450 2C9enzyme
PhenacetinCytochrome P450 2E1enzyme
PhenacetinCytochrome P450 3A4enzyme
PractololBeta-1 adrenergic receptortarget
PractololCytochrome P450 2D6enzyme
PropacetamolCholinesteraseenzyme
PropacetamolProstaglandin G/H synthase 1target
PropacetamolProstaglandin G/H synthase 2target
PropacetamolTransient receptor potential cation channel subfamily V member 1target
PropacetamolCannabinoid receptor 1target
PropacetamolCytochrome P450 2E1enzyme
PropacetamolCytochrome P450 1A2enzyme
PropacetamolCytochrome P450 2D6enzyme
PropacetamolUDP-glucuronosyltransferase 1-1enzyme
PropacetamolUDP-glucuronosyltransferase 1-6enzyme
PropacetamolUDP-glucuronosyltransferase 1-9enzyme
PropacetamolUDP-glucuronosyltransferase 2B15enzyme
PropacetamolUDP-glucuronosyltransferase 1-10enzyme
PropacetamolSulfotransferase 1A1enzyme
PropacetamolSulfotransferase 1A3/1A4enzyme
PropacetamolEstrogen sulfotransferaseenzyme
PropacetamolBile salt sulfotransferaseenzyme
PropacetamolArylamine N-acetyltransferase 2enzyme
PropacetamolCytochrome P450 2C9enzyme
PropacetamolCytochrome P450 3A4enzyme
PilsicainideBile salt export pumptransporter