Deoxyuridine
- Name
- Deoxyuridine
- Accession Number
- DBCAT000608
- Description
2'-Deoxyuridine. An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies.
- Drugs
Drug Drug Description Idoxuridine A pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis. Broxuridine Broxuridine has been used in trials studying the treatment of Leukemia, Stage I Prostate Cancer, Stage IIB Prostate Cancer, and Stage IIA Prostate Cancer. Floxuridine An antimetabolite used as palliative management for liver metastases of gastrointestinal malignancy. Brivudine A drug used to treat herpes zoster. Thymectacin Investigated for use/treatment in colorectal cancer. Doxifluridine Doxifluridine has been investigated for the treatment of Stomach Cancer. - Drugs & Drug Targets
Drug Target Type Idoxuridine Thymidine kinase target Idoxuridine DNA target Floxuridine Thymidylate synthase target Floxuridine Thymidine phosphorylase enzyme Floxuridine Cytochrome P450 2C9 enzyme Floxuridine Thyroxine-binding globulin carrier Brivudine Thymidine kinase 2, mitochondrial target Brivudine DNA polymerase target Brivudine Thymidine kinase target Thymectacin Thymidylate synthase target