Deoxyuridine

Name
Deoxyuridine
Accession Number
DBCAT000608
Description

2'-Deoxyuridine. An antimetabolite that is converted to deoxyuridine triphosphate during DNA synthesis. Laboratory suppression of deoxyuridine is used to diagnose megaloblastic anemias due to vitamin B12 and folate deficiencies.

Drugs
DrugDrug Description
IdoxuridineA pyrimidine analog antiviral used for the treatment of viral eye infections, including herpes simplex keratitis.
BroxuridineBroxuridine has been used in trials studying the treatment of Leukemia, Stage I Prostate Cancer, Stage IIB Prostate Cancer, and Stage IIA Prostate Cancer.
FloxuridineAn antimetabolite used as palliative management for liver metastases of gastrointestinal malignancy.
BrivudineA drug used to treat herpes zoster.
ThymectacinInvestigated for use/treatment in colorectal cancer.
DoxifluridineDoxifluridine has been investigated for the treatment of Stomach Cancer.
Drugs & Drug Targets
DrugTargetType
IdoxuridineThymidine kinasetarget
IdoxuridineDNAtarget
FloxuridineThymidylate synthasetarget
FloxuridineThymidine phosphorylaseenzyme
FloxuridineCytochrome P450 2C9enzyme
FloxuridineThyroxine-binding globulincarrier
BrivudineThymidine kinase 2, mitochondrialtarget
BrivudineDNA polymerasetarget
BrivudineThymidine kinasetarget
ThymectacinThymidylate synthasetarget