Anti-Infective Agents, Urinary

Substances capable of killing agents causing urinary tract infections or of preventing them from spreading.
DrugDrug NameDrug Description
DB00260CycloserineA broad-spectrum antibiotic used in the treatment of tuberculosis and certain urinary tract infections (UTI).
DB00440TrimethoprimA pyrimidine inhibitor of dihydrofolate reductase often used with sulfamethoxazole as an antibiotic to treat Shigellosis, Pneumocystis jirovecii pneumonia and certain susceptible urinary tract infections.
DB00614FurazolidoneFor the specific and symptomatic treatment of bacterial or protozoal diarrhea and enteritis caused by susceptible organisms.
DB00634SulfacetamideA corticosteroid used to treat inflammatory ocular conditions and acne vulgaris.
DB00664SulfametopyrazineFor the treatment of urinary tract infection and chronic bronchitis.
DB00698NitrofurantoinAn antibiotic used to treat urinary tract infections.
DB01137LevofloxacinA fluoroquinolone used to treat infections including the upper respiratory tract, skin and skin structure, urinary tract, as well as pneumonia, chronic bacterial prostatitis, post exposure treatment of inhaled anthrax, and the plague.
DB01163AmdinocillinUsed in the treatment of urinary tract infections caused by some strains of E. coli and klebsiella and enterobacter species. Used mainly against Gram negative organisms.
DB01165OfloxacinAn antibacterial agent used for the treatment of bacterial infections in many parts of the body, including the respiratory tract, kidney, skin, soft tissue, and urinary tract.
DB01299SulfadoxineA long acting sulfonamide used for the treatment or prevention of malaria.
DB01422NitroxolineNitroxoline is an antibiotic agent.
DB01605PivmecillinamA prodrug of the beta lactam antibiotic mecillinam, indicated for the treatment of uncomplicated urinary tract infections (UTIs).
DB06799MethenamineA urinary tract antiseptic and antibacterial drug used for the prophylaxis and treatment of frequently recurring urinary tract infections requiring a long-term therapy.
DB06821SulfameterLong acting sulfonamide used in leprosy, urinary, and respiratory tract infections.
DB08972FlumequineFlumequine is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class used to treat bacterial infections.
DB09047FinafloxacinFinafloxacin is indicated for the treatment of acute otitis externa (AOE) with or without an otowick, caused by susceptible strains of Pseudomonas aeruginosa and Staphylococcus aureus in patients age 1...
DB11461SulfachlorpyridazineA sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.
DB13475FurazidinNot Annotated
DB13506CarfecillinNot Annotated
DB13627Oxolinic acidNot Annotated
DB13730NifurtoinolNot Annotated
DB13744Piromidic acidNot Annotated
DB13823Pipemidic acidNot Annotated
DB00828FosfomycinA broad spectrum antibiotic used to treat uncomplicated urinary tract infections.
DrugDrug NameTargetType
DB00260CycloserineD-alanine--D-alanine ligase Atarget
DB00260CycloserineAlanine racemasetarget
DB00260CycloserineAromatic-L-amino-acid decarboxylaseenzyme
DB00260CycloserineProton-coupled amino acid transporter 2transporter
DB00440TrimethoprimThymidylate synthasetarget
DB00440TrimethoprimDihydrofolate reductasetarget
DB00440TrimethoprimCytochrome P450 2C8enzyme
DB00440TrimethoprimCytochrome P450 3A4enzyme
DB00440TrimethoprimP-glycoprotein 1transporter
DB00440TrimethoprimCytochrome P450 2C9enzyme
DB00440TrimethoprimSolute carrier family 22 member 2transporter
DB00614FurazolidoneDNAtarget
DB00614FurazolidoneAmine oxidase [flavin-containing] Benzyme
DB00614FurazolidoneAmine oxidase [flavin-containing] Aenzyme
DB00634SulfacetamideDihydropteroate synthasetarget
DB00634SulfacetamideDihydropteroate synthase type-1target
DB00634SulfacetamideFolic acid synthesis protein FOL1target
DB00664SulfametopyrazineDihydropteroate synthetasetarget
DB00698Nitrofurantoin30S ribosomal protein S10target
DB00698NitrofurantoinOxygen-insensitive NADPH nitroreductasetarget
DB00698NitrofurantoinProbable pyruvate-flavodoxin oxidoreductasetarget
DB00698NitrofurantoinATP-binding cassette sub-family G member 2transporter
DB00698NitrofurantoinNADPH--cytochrome P450 reductaseenzyme
DB00698NitrofurantoinBile salt export pumptransporter
DB00698NitrofurantoinP-glycoprotein 1transporter
DB00698NitrofurantoinCanalicular multispecific organic anion transporter 1transporter
DB01137LevofloxacinDNA gyrase subunit Atarget
DB01137LevofloxacinDNA topoisomerase 4 subunit Atarget
DB01137LevofloxacinDNA topoisomerase 2-alphatarget
DB01137LevofloxacinCytochrome P450 1A2enzyme
DB01137LevofloxacinSolute carrier family 22 member 2transporter
DB01137LevofloxacinP-glycoprotein 1transporter
DB01137LevofloxacinSolute carrier family 22 member 4transporter
DB01137LevofloxacinSolute carrier family 22 member 6transporter
DB01137LevofloxacinCytochrome P450 3A4enzyme
DB01137LevofloxacinMultidrug and toxin extrusion protein 1transporter
DB01137LevofloxacinMultidrug and toxin extrusion protein 2transporter
DB01137LevofloxacinCytochrome P450 2C9enzyme
DB01163AmdinocillinPenicillin-binding protein 2target
DB01163AmdinocillinPenicillin-binding protein 2atarget
DB01163AmdinocillinPenicillin-binding protein 3target
DB01163AmdinocillinPenicillin-binding protein 1Atarget
DB01163AmdinocillinPenicillin-binding protein 2Btarget
DB01163AmdinocillinPenicillin-binding protein 1btarget
DB01165OfloxacinDNA gyrase subunit Atarget
DB01165OfloxacinDNA topoisomerase 4 subunit Atarget
DB01165OfloxacinDNA topoisomerase 2-alphatarget
DB01165OfloxacinCytochrome P450 1A2enzyme
DB01165OfloxacinSolute carrier family 22 member 5transporter
DB01165OfloxacinMultidrug resistance-associated protein 1transporter
DB01165OfloxacinSolute carrier family 22 member 6transporter
DB01165OfloxacinCanalicular multispecific organic anion transporter 1transporter
DB01165OfloxacinSolute carrier family 22 member 4transporter
DB01165OfloxacinBile salt export pumptransporter
DB01299SulfadoxineDihydropteroate synthetasetarget
DB01299SulfadoxineBifunctional dihydrofolate reductase-thymidylate synthasetarget
DB01422NitroxolineMethionine aminopeptidase 2target
DB01422NitroxolineMagnesium cationtarget
DB01422NitroxolineManganese cationtarget
DB01605PivmecillinamPenicillin-binding protein 1Atarget
DB06821SulfameterDihydropteroate synthasetarget
DB08972FlumequineCytochrome P450 1A2enzyme
DB09047FinafloxacinDNA gyrase subunit Atarget
DB09047FinafloxacinDNA topoisomerase 4 subunit Atarget
DB09047FinafloxacinDNA topoisomerase 2-alphatarget
DB13627Oxolinic acidCytochrome P450 1A2enzyme
DB13823Pipemidic acidCytochrome P450 1A2enzyme
DB00828FosfomycinUDP-N-acetylglucosamine 1-carboxyvinyltransferasetarget