Agrochemicals

Chemicals used in agriculture. These include pesticides, fumigants, fertilizers, plant hormones, steroids, antibiotics, mycotoxins, etc.
DrugDrug NameDrug Description
DB00265CrotamitonA topical scabicidal and antipruritic agent used for scabies eradication and for the relief of pruritus.
DB00431LindaneAn ectoparasiticide and ovicide used in the treatment of Pediculosis humanis capitis (head lice) and Phthirus pubis (crab lice).
DB00602IvermectinAn anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis.
DB00676Benzyl benzoateUsed to kill lice and the mites responsible for the skin condition scabies.
DB00682WarfarinA vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction.
DB00772MalathionA parasympathomimetic organophosphate used to treat head lice.
DB03895Malachite GreenNot Available
DB04539GlyphosateNot Available
DB04628AllosamidinAllosamidin exhibits extremely potent inhibitory activity against chitinases from a number of sources, particularly from Candida albicans, and can be utilized as potent antifungal agent.
DB04657CarboxinA systemic agricultural fungicide and seed treatment agent.
DB04930PermethrinAn insecticide used to prevent infestation with Sarcoptes scabiei (scabies).
DB06803NiclosamideFor the treatment of tapeworm and intestinal fluke infections: Taenia saginata (Beef Tapeworm), Taenia solium (Pork Tapeworm), Diphyllobothrium latum (Fish Tapeworm), Fasciolopsis buski (large intestinal fluke). Niclosamide is also used...
DB08823SpinosadA pediculicide used topically to treat head lice.
DB09350Piperonyl butoxideA pesticide used as a potentiator ingredient in the treatment of pediculosis (head lice, body lice or crabs) to boost efficacy of treatment.
DB11087Pyrethrum extractA chrysanthemum flower extract used to treat head, pubic, and body lice.
DB11282DiethyltoluamideAn insect repellant, also known as DEET.
DB11326Boric acidNo FDA- or EMA-approved therapeutic indications on its own.
DB11373AmitrazAmitraz is a non-systemic acaricide and insecticide. It was generated in 1969 by the Boots Co. in England. Amitraz presents insect repellent effects and hence, it can be used as...
DB11390CoumaphosThis drug is a fat-soluble phosphorothioate agent that kills both insects and mites. It is non-volatile in nature and is well known by a variety of names as such a...
DB11392CythioateCythioate is a member of the organothiophosphate compounds that is used as an insecticide and anthelmintic. It is mainly used in veterinary as a treatment for fleas.
DB11397DichlorvosDichlorvos or 2,2-dichlorovinyl dimethyl phosphate is a drug of the organophosphate class, frequently used as an insecticide for the control of indoor pests and for the protection of stored products...
DB11400DoramectinDoramectin is a veterinary drug approved by the Food and Drug Administration for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice and mange mites in...
DB11405EprinomectinNot Annotated
DB11408FamphurNot Annotated
DB11412FenthionFenthion is an organothiophosphate drug used as an insecticide, avicide, and acaricide. Its mode of action is explained by cholinesterase enzyme inhibition, which is similar to other organophosphates. Fenthion is...
DB11421ImidaclopridImidacloprid is a neonicotinoid, which is a class of neuro-active insecticides modeled after nicotine. Imidacloprid is a patented chemical, Imidacloprid is manufactured by Bayer Cropscience (part of Bayer AG) and...
DB11424LufenuronLufenuron is used in veterinary for the control of flea.
DB11431MoxidectinMoxidectin is indicated for the treatment of river blindness, also called onchocerciasis, in patients aged 12 years and older. River blindness is caused by a parasitic worm Onchocerca volvulus and...
DB11448PhosmetPhosmet is a phthalimide-derived organophosphate. It is a non-specific insecticide. It is mainly used on apple trees to control codling moths. It is also used on other fruit crops, ornamentals,...
DB11457RotenoneRotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also...
DB11473MetrifonateMetrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
DB12231TemefosDiphos has been used in trials studying the treatment of Plasmodium Falciparum Malaria.
DB12989NeosaxitoxinNeosaxitoxin is under investigation in clinical trial NCT01786655 (Safety Study of Long-Acting Local Anesthetic).
DB13009CarbendazimCarbendazim has been used in trials studying the treatment of Lymphoma and Unspecified Adult Solid Tumor, Protocol Specific.
DB13245ThiramThiram may be used in dermatology as a scabicide. Thiram is mainly used as a fungicide for plants and treatment for seeds, however, this use is being investigated for safety...
DB13336DimethylphthalateNot Annotated
DB13495ParaoxonNot Annotated
DB13600DeltamethrinNot Annotated
DB13717PhenothrinNot Annotated
DB13721CypermethrinNot Annotated
DB13746BioallethrinBioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin.
DB13752TetramethrinNot Annotated
DB13828CyfluthrinNot Annotated
DB139631,2-dichlorobenzene1,2-Dichlorobenzene, also named ortho-dichlorobenzene, is an organic compound. It is a non-polar colorless liquid that is miscible in most organic solvents. This derivative of benzene differs from the parent compound...
DB14150Chloric acidNot Annotated
DB07338AcifluorfenAcifluorfen is a protoporphyrinogen oxidase inhibitor.
DB02994Cacodylic acidNot Available
DB01460DiethyltryptamineDiethyltryptamine (DET) is an orally active hallucinogenic agent and a substituted form of tryptamine.
DB14972MethamidophosMethamidophos is under investigation in clinical trial NCT03223753 (Web-Based Physical Activity Intervention in Improving Long Term Health in Children and Adolescents With Newly Diagnosed Acute Lymphoblastic Leukemia in First Remission).
DB03852EucalyptolA common ingredient in mouthwash and cosmetics derived naturally from the eucalyptus plant that is frequently used to to improve symptoms of airway mucus hypersecretion.
DB04582IMAZAQUINNot Available
DB05252Fenoxaprop-ethylChronic angina and Coronary Artery Disease
DB11438NitenpyramNitenpyram is an insecticide used in agriculture and veterinary medicine to kill external parasites of pets. It is a neonicotinoid, a neurotoxin that blocks neural messages and binds particularly tightly...
DB12728FenpropidinFenpropidin has been investigated for the treatment of Hernia.
DB15117TransfluthrinTransfluthrin is under investigation in clinical trial NCT02394522 (Spatial Repellent Products for Control of Vector Borne Diseases - Malaria - Zambia (SR-M-ZM)).
DrugDrug NameTargetType
DB00431LindaneGamma-aminobutyric acid receptor subunit beta-1target
DB00431LindaneGlycine receptor subunit alpha-1target
DB00431LindaneGlycine receptor subunit alpha-2target
DB00431LindaneGlycine receptor subunit alpha-3target
DB00431LindaneGlycine receptor subunit betatarget
DB00431LindaneGamma-aminobutyric acid receptor subunit beta-3target
DB00431LindaneGamma-aminobutyric acid receptor subunit rho-1target
DB00431LindaneProgesterone receptortarget
DB00431LindaneEstrogen receptor alphatarget
DB00431LindaneNuclear receptor subfamily 1 group I member 2target
DB00602IvermectinGamma-aminobutyric acid receptor subunit beta-3target
DB00602IvermectinGlycine receptor subunit alpha-3target
DB00602IvermectinP-glycoprotein 1transporter
DB00602IvermectinMultidrug resistance-associated protein 1transporter
DB00602IvermectinCanalicular multispecific organic anion transporter 1transporter
DB00602IvermectinATP-binding cassette sub-family G member 2transporter
DB00602IvermectinCytochrome P450 3A4enzyme
DB00602IvermectinSolute carrier organic anion transporter family member 1B1transporter
DB00602IvermectinSolute carrier organic anion transporter family member 1B3transporter
DB00682WarfarinVitamin K epoxide reductase complex subunit 1target
DB00682WarfarinCytochrome P450 2C8enzyme
DB00682WarfarinCytochrome P450 1A2enzyme
DB00682WarfarinCytochrome P450 2C9enzyme
DB00682WarfarinAlpha-1-acid glycoprotein 1carrier
DB00682WarfarinSerum albumincarrier
DB00682WarfarinCytochrome P450 2C19enzyme
DB00682WarfarinCytochrome P450 3A4enzyme
DB00682WarfarinCytochrome P450 2C18enzyme
DB00682WarfarinNuclear receptor subfamily 1 group I member 2target
DB00772MalathionCholinesterasetarget
DB00772MalathionCytochrome P450 1A2enzyme
DB00772MalathionCytochrome P450 2B6enzyme
DB03895Malachite GreenHTH-type transcriptional regulator QacRtarget
DB04539Glyphosate3-phosphoshikimate 1-carboxyvinyltransferasetarget
DB04539Glyphosate3-phosphoshikimate 1-carboxyvinyltransferasetarget
DB04539GlyphosateCytochrome P450 19A1target
DB04539GlyphosateSerum albumincarrier
DB04628AllosamidinChitinase Btarget
DB04628AllosamidinChitinase Atarget
DB04657CarboxinSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialtarget
DB04930PermethrinCytochrome P450 2B6enzyme
DB04930PermethrinSodium channel protein type 1 subunit alphatarget
DB04930PermethrinEstrogen receptor alphatarget
DB04930PermethrinNuclear receptor subfamily 1 group I member 2target
DB06803NiclosamideDNAtarget
DB06803NiclosamideCytochrome P450 2C9enzyme
DB06803NiclosamideCytochrome P450 1A2enzyme
DB11087Pyrethrum extractNuclear receptor subfamily 1 group I member 2target
DB11397DichlorvosSerum albumincarrier
DB11397DichlorvosSerotransferrintarget
DB11397DichlorvosCholinesterasetarget
DB11400DoramectinCytochrome P450 3A4enzyme
DB11405EprinomectinCytochrome P450 3A4enzyme
DB11421ImidaclopridCHRNA7-FAM7A fusion proteintarget
DB11431MoxidectinCYP3Aenzyme
DB11431MoxidectinCYP2B proteinenzyme
DB11431MoxidectinP-glycoprotein 1transporter
DB11431MoxidectinATP-binding cassette sub-family G member 2transporter
DB11431MoxidectinGlutamate-gated chloride channeltarget
DB11431MoxidectinGABA-A gated chloride channeltarget
DB11431MoxidectinABC transporterstarget
DB13746BioallethrinVoltage-gated sodium channel alpha subunittarget
DB13746BioallethrinSodium channel proteintarget
DB13746BioallethrinVoltage-dependent calcium channeltarget
DB13746BioallethrinVoltage-dependent T-type calcium channeltarget
DB13746BioallethrinVoltage-dependent P/Q-type calcium channeltarget
DB13746BioallethrinVoltage-dependent L-type calcium channeltarget
DB13746BioallethrinCytochrome P450 2C8enzyme
DB13746BioallethrinCytochrome P450 2C9enzyme
DB13746BioallethrinCytochrome P450 2C19enzyme
DB13746BioallethrinCytochrome P450 3A4enzyme
DB13746BioallethrinCytochrome P450 2A1enzyme
DB13746BioallethrinCytochrome P450 1A1enzyme
DB13746BioallethrinCytochrome P450 2C6enzyme
DB13746BioallethrinCytochrome P450 2C11enzyme
DB13746BioallethrinCytochrome P450 3A1enzyme
DB13746BioallethrinCytochrome P450 3A2enzyme
DB139631,2-dichlorobenzeneCytochrome P450 2E1enzyme
DB07338AcifluorfenProtoporphyrinogen oxidasetarget
DB07338AcifluorfenProtoporphyrinogen oxidasetarget
DB02994Cacodylic acidGag-Pol polyproteintarget
DB02994Cacodylic acidNitric oxide synthase, endothelialtarget
DB02994Cacodylic acidAldose reductasetarget
DB02994Cacodylic acidGuanine nucleotide-binding protein G(t) subunit alpha-1target
DB05252Fenoxaprop-ethylNitric oxide synthase, inducibletarget