Sugar Alcohols

Polyhydric alcohols having no more than one hydroxy group attached to each carbon atom. They are formed by the reduction of the carbonyl group of a sugar to a hydroxyl group.(From Dorland, 28th ed)
DrugDrug NameDrug Indication
DB00271DiatrizoateUsed, alone or in combination, for a wide variety of diagnostic imaging methods, including angiography, urography, cholangiography, computed tomography, hysterosalpingography, and retrograde pyelography. It can be used for imaging the gastrointestinal tract in patients allergic to barium.
DB00727NitroglycerinFor the prevention of angina
DB00742MannitolUsed for the promotion of diuresis before irreversible renal failure becomes established, the reduction of intracranial pressure, the treatment of cerebral edema, and the promotion of urinary excretion of toxic substances.
DB00743Gadobenic acidGadobenate Dimeglumine is an MRI contrast agent used primarily for MR imaging of the liver. It can also be used for MRI of the heart, as well as and central nervous system in adults to visualize lesions with abnormal brain vascularity or abnormalities in the blood brain barrier, the brain, spine, or other associated tissues.
DB00883Isosorbide DinitrateFor the prevention of angina pectoris due to coronary artery disease.
DB01020Isosorbide MononitrateFor the prevention of angina pectoris due to coronary artery disease and the treatment of acute and chronic angina pectoris, hypertension, and myocardial infarction.
DB01613Erythrityl TetranitrateFor the prevention of angina.
DB01638SorbitolUsed as a non-stimulant laxative via an oral suspension or enema.
DB01692DithioerythritolNot Available
DB018402-Deoxy-D-Glucitol 6-(E)-VinylhomophosphonateNot Available
DB018594-Diphosphocytidyl-2-C-Methyl-D-Erythritol 2-PhosphateNot Available
DB01863Inositol 1,3,4,5-TetrakisphosphateNot Available
DB021722,5-Dideoxy-2,5-Imino-D-GlucitolNot Available
DB02261Platelet Activating FactorNot Available
DB02492GhavamiolNot Available
DB02942Inositol 1,3-BisphosphateNot Available
DB03864MonothioglycerolNot Available
DB04878VogliboseFor the treatment of diabetes. It is specifically used for lowering post-prandial blood glucose levels thereby reducing the risk of macrovascular complications.
DB08909Glycerol PhenylbutyrateGlycerol phenylbutyrate is a nitrogen-binding agent for the chronic management of adult and pediatric patients ≥2 years of age with urea cycle disorders (UCDs) who cannot be managed by dietary protein restriction and/or amino acid supplementation alone.
DB09132Gadoteric acidGadoteric acid is indicated for intravenous use with magnetic resonance imaging (MRI) in brain (intracranial), spine and associated tissues in adult and pediatric patients (2 years of age and older) to detect and visualize areas with disruption of the blood brain barrier (BBB) and/or abnormal vascularity.
DB09133Iothalamic acidConray is indicated for use in excretory urography, cerebral angiography, peripheral arteriography, venography, arthrography, direct cholangiography, endoscopic retrograde cholangiopancreatography, contrast enhancement of computed tomographic brain images, cranial computerized angiotomography, intravenous digital subtraction angiography and arterial digital subtraction angiography. Conray may also be used for enhancement of computed tomographic scans performed for detection and evaluation of lesions in the liver, pancreas, kidneys, abdominal aorta, mediastinum, abdominal cavity and retroperitoneal space.
DB09462GlycerinIt is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.
DB11195XylitolNot Available
DB12214LuseogliflozinNot Available
DB12873DianhydrogalactitolNot Available
DB12916MitolactolNot Available
DB12969MethylinositolNot Available
DB13178myo-inositolNot Available
DrugDrug NameTargetType
DB00727NitroglycerinAtrial natriuretic peptide receptor 1target
DB00727NitroglycerinAldehyde dehydrogenase, mitochondrialenzyme
DB00742MannitolMultidrug resistance protein 1transporter
DB00742MannitolMannitol dehydrogenaseenzyme
DB00743Gadobenic acidSerum albumincarrier
DB00883Isosorbide DinitrateAtrial natriuretic peptide receptor 1target
DB00883Isosorbide DinitrateCytochrome P450 3A4enzyme
DB00883Isosorbide DinitrateCytochrome P450 2E1enzyme
DB01020Isosorbide MononitrateCytochrome P450 3A4enzyme
DB01020Isosorbide MononitrateGuanylate cyclase soluble subunit alpha-2target
DB01613Erythrityl TetranitrateAtrial natriuretic peptide receptor 1target
DB01613Erythrityl TetranitrateAtrial natriuretic peptide receptor 2target
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolMalate synthase Gtarget
DB01692DithioerythritolListeriolysin regulatory proteintarget
DB01692Dithioerythritol6,7-dimethyl-8-ribityllumazine synthasetarget
DB01692DithioerythritolThymidine kinase, cytosolictarget
DB018402-Deoxy-D-Glucitol 6-(E)-VinylhomophosphonateInositol-3-phosphate synthase 1target
DB018594-Diphosphocytidyl-2-C-Methyl-D-Erythritol 2-Phosphate2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthasetarget
DB01863Inositol 1,3,4,5-TetrakisphosphateRAC-alpha serine/threonine-protein kinasetarget
DB01863Inositol 1,3,4,5-TetrakisphosphatePleckstrin homology domain-containing family A member 4target
DB01863Inositol 1,3,4,5-TetrakisphosphateTyrosine-protein kinase BTKtarget
DB01863Inositol 1,3,4,5-TetrakisphosphateDual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositidetarget
DB01863Inositol 1,3,4,5-TetrakisphosphateInositol-trisphosphate 3-kinase Atarget
DB01863Inositol 1,3,4,5-TetrakisphosphateCytohesin-2target
DB01863Inositol 1,3,4,5-TetrakisphosphateCytohesin-3target
DB01863Inositol 1,3,4,5-Tetrakisphosphate3-phosphoinositide-dependent protein kinase 1target
DB021722,5-Dideoxy-2,5-Imino-D-GlucitolXylose isomerasetarget
DB02261Platelet Activating FactorGanglioside GM2 activatortarget
DB02261Platelet Activating FactorMultidrug resistance protein 1transporter
DB02261Platelet Activating FactorPlatelet-activating factor receptortarget
DB02492GhavamiolAlpha-mannosidase 2target
DB02942Inositol 1,3-BisphosphateEarly endosome antigen 1target
DB03864MonothioglycerolProlyl endopeptidasetarget
DB04878VogliboseMaltase-glucoamylase, intestinaltarget
DB08909Glycerol PhenylbutyratePancreatic triacylglycerol lipaseenzyme
DB08909Glycerol PhenylbutyrateCytochrome P450 3A4enzyme
DB08909Glycerol PhenylbutyrateCytochrome P450 1A2enzyme
DB08909Glycerol PhenylbutyrateCytochrome P450 2D6enzyme
DB09462GlycerinHematopoietic prostaglandin D synthasetarget
DB09462GlycerinEndoglucanase Gtarget
DB09462GlycerinGlutathione S-transferase Ptarget
DB09462GlycerinGroup IIE secretory phospholipase A2target
DB09462GlycerinInositol-3-phosphate synthase 1target
DB09462GlycerinC4-dicarboxylate transport transcriptional regulatory protein DctDtarget
DB09462GlycerinAlcohol dehydrogenase 1Btarget
DB09462GlycerinInositol 1,4,5-trisphosphate receptor type 1target
DB09462GlycerinGlycodelintarget
DB09462GlycerinAlpha-N-acetylgalactosaminidasetarget
DB09462GlycerinCytochrome c4target
DB09462GlycerinBacterioferritintarget
DB09462GlycerinTGF-beta receptor type-2target
DB09462GlycerinArgininosuccinate synthasetarget
DB09462GlycerinEnolasetarget
DB09462GlycerinADP-ribosylation factor 1target
DB09462GlycerinMultidrug resistance protein MexAtarget
DB09462GlycerinBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1target
DB09462GlycerinHistidinol dehydrogenasetarget
DB09462GlycerinDNA mismatch repair protein MutLtarget
DB09462GlycerinGlycerol uptake facilitator proteintarget
DB09462GlycerinRibonucleoside-diphosphate reductase 1 subunit betatarget
DB09462GlycerinA/G-specific adenine glycosylasetarget
DB09462GlycerintRNA (cytosine(38)-C(5))-methyltransferasetarget
DB09462GlycerinMultidrug resistance protein 1transporter
DB09462GlycerinCytochrome P450 2E1enzyme
DB09462GlycerinRetinal dehydrogenase 1enzyme
DB09462GlycerinMultidrug resistance protein 1transporter
DB09462GlycerinPeroxisome proliferator-activated receptor deltatarget