Sugar Alcohols

Name
Sugar Alcohols
Accession Number
DBCAT000648
Description

Polyhydric alcohols having no more than one hydroxy group attached to each carbon atom. They are formed by the reduction of the carbonyl group of a sugar to a hydroxyl group.(From Dorland, 28th ed)

Drugs
DrugDrug Description
DiatrizoateAn injected contrast agent used in radiology.
MannitolA sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, and to measure glomerular filtration rate.
Gadobenic acidA gadolinium compound used as a contrast agent in MRIs.
Isosorbide dinitrateA vasodilator used to treat angina in coronary artery disease.
Isosorbide mononitrateA nitrate used to prevent and treat angina and to treat angina caused by coronary artery disease.
Erythrityl tetranitrateFor the prevention of angina.
SorbitolA product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener.
DithioerythritolA compound that, along with its isomer, Cleland's reagent (dithiothreitol), is used for the protection of sulfhydryl groups against oxidation to disulfides and for the reduction of disulfides to sulfhydryl...
2-Deoxy-D-Glucitol 6-(E)-VinylhomophosphonateNot Available
Inositol 1,3,4,5-TetrakisphosphateNot Available
2,5-Dideoxy-2,5-Imino-D-GlucitolNot Available
Platelet Activating FactorNot Available
GhavamiolNot Available
Inositol 1,3-BisphosphateNot Available
MonothioglycerolNot Available
VogliboseFor the treatment of diabetes. It is specifically used for lowering post-prandial blood glucose levels thereby reducing the risk of macrovascular complications.
Glycerol phenylbutyrateA nitrogen-binding agent used to manage patients with urea cycle disorders who cannot be sufficiently managed amino acid supplementation and/or dietary restrictions.
Gadoteric acidA diagnostic contrast agent used with magnetic resonance imaging to provide contrast enhancement for intracranial and spinal lesions with abnormal blood brain barrier or abnormal vascularity, and for whole body imaging.
Iothalamic acidA diagnostic contrast agent used in various medical imaging procedures, such as angiography, arthrography, and computed tomographic scans.
IsosorbideA vasodilator used for the prevention and treatment of angina pectoris due to coronary artery disease.
GlycerinIt is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.
XylitolAn ingredient added to dental products to remove bacteria.
LuseogliflozinLuseogliflozin has been used in trials studying the treatment of Diabetes Melltius, Type 2.
DianhydrogalactitolDianhydrogalactitol has been used in trials studying the treatment of GBM, Glioma, Glioblastoma, Brain Cancer, and Glioblastoma Multiforme.
MitolactolMitolactol has been used in trials studying the treatment of Brain and Central Nervous System Tumors.
MethylinositolMethylinositol has been used in trials studying the treatment of Dementia and Alzheimer's Disease.
InositolAn ingredient found in a variety of nutritional products.
Ioxitalamic acidA contrast agent used for CT scans of the abdomen and pelvis.
MitobronitolNot Annotated
Meglumine antimoniateNot Annotated
EthylhexylglycerinAn emollient solvent with antimicrobial activity.
RibitolNot Annotated
scyllo-inositolAn isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been...
1D-myo-inositol 1,4,5-trisphosphateIntracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the...
2,3-di-O-phytanyl-sn-glycerolNot Available
Inositol 2,4,5-trisphosphateNot Available
Phosphatidyl serineA nutrient used in some supplement products.
LysophosphatidylglycerolNot Available
Indole-3-Glycerol PhosphateNot Available
PhosphatidylethanolamineNot Available
Choline alfoscerateA component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes...
LucinactantIntended for the prevention of respiratory distress syndrome (RDS) in premature infants at high risk for RDS.
ETC-588Investigated for use/treatment in atherosclerosis, coronary artery disease, and vascular diseases.
Colfosceril palmitateA pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants.
Sodium glycerophosphateA medication used to treat hypophosphatemia.
DL-dimyristoylphosphatidylcholineDL-dimyristoylphosphatidylcholine is not an active pharmaceutical agent and has no indication.
DL-dimyristoylphosphatidylglycerolDL-dimyristoylphosphatidylglycerol is not an considered an active pharmacological ingredient in pharmaceutical preparations and so has no official indications.
MifamurtideA muramyl dipeptide derivative used to treat high grade, resectable, non-metastatic osteosarcoma after surgical resection.
1,2-DistearoyllecithinNot Annotated
VB-201VB-201 is under investigation in clinical trial NCT01001468 (Study to Assess VB-201 in Patients With Psoriasis).
Iocarmic acidNot Annotated
1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamineNot Available
Glycerol 2-phosphateNot Available
L-DilinoleoyllecithinNot Available
sn-glycero-3-phosphoethanolamineNot Available
CadaverineCadaverine is a foul-smelling diamine formed by bacterial decarboxylation of lysine.
ErythritolErythritol is a four-carbon sugar that is found in algae, fungi, and lichens. It is twice as sweet as sucrose and can be used as a coronary vasodilator.
1D-myo-inositol 1,3,4-trisphosphateNot Available
Drugs & Drug Targets
DrugTargetType
MannitolMannitol dehydrogenaseenzyme
Gadobenic acidSerum albumincarrier
Isosorbide dinitrateAtrial natriuretic peptide receptor 1target
Isosorbide dinitrateCytochrome P450 2E1enzyme
Isosorbide mononitrateGuanylate cyclase soluble subunit alpha-2target
Isosorbide mononitrateGlutathione S-transferase Mu 1enzyme
Isosorbide mononitrateXanthine dehydrogenase/oxidaseenzyme
Isosorbide mononitrateAlcohol dehydrogenase class-3enzyme
Erythrityl tetranitrateAtrial natriuretic peptide receptor 1target
Erythrityl tetranitrateAtrial natriuretic peptide receptor 2target
DithioerythritolListeriolysin regulatory proteintarget
Dithioerythritol6,7-dimethyl-8-ribityllumazine synthasetarget
DithioerythritolThymidine kinase, cytosolictarget
2-Deoxy-D-Glucitol 6-(E)-VinylhomophosphonateInositol-3-phosphate synthase 1target
Inositol 1,3,4,5-TetrakisphosphateRAC-alpha serine/threonine-protein kinasetarget
Inositol 1,3,4,5-TetrakisphosphatePleckstrin homology domain-containing family A member 4target
Inositol 1,3,4,5-TetrakisphosphateTyrosine-protein kinase BTKtarget
Inositol 1,3,4,5-TetrakisphosphateDual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositidetarget
Inositol 1,3,4,5-TetrakisphosphateInositol-trisphosphate 3-kinase Atarget
Inositol 1,3,4,5-TetrakisphosphateCytohesin-2target
Inositol 1,3,4,5-TetrakisphosphateCytohesin-3target
Inositol 1,3,4,5-Tetrakisphosphate3-phosphoinositide-dependent protein kinase 1target
2,5-Dideoxy-2,5-Imino-D-GlucitolXylose isomerasetarget
Platelet Activating FactorGanglioside GM2 activatortarget
Platelet Activating FactorP-glycoprotein 1transporter
Platelet Activating FactorPlatelet-activating factor receptortarget
GhavamiolAlpha-mannosidase 2target
Inositol 1,3-BisphosphateEarly endosome antigen 1target
MonothioglycerolProlyl endopeptidasetarget
VogliboseMaltase-glucoamylase, intestinaltarget
Glycerol phenylbutyratePancreatic triacylglycerol lipaseenzyme
Glycerol phenylbutyrateCytochrome P450 3A4enzyme
Glycerol phenylbutyrateCytochrome P450 2D6enzyme
IsosorbideApoptosis regulator Bcl-2target
IsosorbideBcl-2-like protein 1target
IsosorbideInduced myeloid leukemia cell differentiation protein Mcl-1target
GlycerinGroup IIE secretory phospholipase A2target
GlycerinInositol-3-phosphate synthase 1target
GlycerinAlcohol dehydrogenase 1Btarget
GlycerinInositol 1,4,5-trisphosphate receptor type 1target
GlycerinGlycodelintarget
GlycerinAlpha-N-acetylgalactosaminidasetarget
GlycerinADP-ribosylation factor 1target
GlycerinBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1target
GlycerinDNA mismatch repair protein MutLtarget
GlycerinRibonucleoside-diphosphate reductase 1 subunit betatarget
GlycerinA/G-specific adenine glycosylasetarget
GlycerintRNA (cytosine(38)-C(5))-methyltransferasetarget
GlycerinCytochrome P450 2E1enzyme
GlycerinRetinal dehydrogenase 1enzyme
GlycerinPeroxisome proliferator-activated receptor deltatarget
GlycerinMaleylacetoacetate isomerasetarget
GlycerinAquaporin-7transporter
GlycerinAquaporin-9transporter
GlycerinGlycerol uptake facilitator proteintransporter
XylitolXylose isomerasetarget
XylitolXylose isomerasetarget
XylitolXylose isomerasetarget
XylitolXylose isomerasetarget
XylitolHyaluronate lyasetarget
InositolSodium/myo-inositol cotransportertransporter
scyllo-inositolGlucosylceramidasetarget
scyllo-inositol1-phosphatidylinositol phosphodiesterasetarget
scyllo-inositolCDP-diacylglycerol--inositol 3-phosphatidyltransferasetarget
scyllo-inositol1-phosphatidylinositol phosphodiesterasetarget
1D-myo-inositol 1,4,5-trisphosphateCytohesin-2target
1D-myo-inositol 1,4,5-trisphosphateEpsin-1target
1D-myo-inositol 1,4,5-trisphosphate1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1target
1D-myo-inositol 1,4,5-trisphosphateRadixintarget
1D-myo-inositol 1,4,5-trisphosphateSpectrin beta chain, non-erythrocytic 1target
1D-myo-inositol 1,4,5-trisphosphateInositol 1,4,5-trisphosphate receptor type 1target
1D-myo-inositol 1,4,5-trisphosphateInositol-trisphosphate 3-kinase Atarget
Inositol 2,4,5-trisphosphate1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1target
Phosphatidyl serinePhosphatidylserine decarboxylase proenzymetarget
Phosphatidyl serineScavenger receptor class B member 1target
Phosphatidyl serineProtein kinase C alpha typetarget
Phosphatidyl serinePhosphatidylserine synthase 1target
Phosphatidyl serineDiacylglycerol kinase gammatarget
Phosphatidyl serineDiacylglycerol kinase deltatarget
Phosphatidyl serinePhosphatidylserine synthase 2target
Phosphatidyl serineSphingomyelin phosphodiesterase 4target
Phosphatidyl serineSphingomyelin phosphodiesterase 3target
Phosphatidyl serineProbable phospholipid-transporting ATPase IAtarget
Indole-3-Glycerol PhosphateTryptophan synthase alpha chaintarget
Indole-3-Glycerol PhosphateTryptophan synthase beta chaintarget
PhosphatidylethanolamineEndothelial protein C receptortarget
PhosphatidylethanolamineBacteriorhodopsintarget
PhosphatidylethanolaminePhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENtarget
Choline alfoscerateGanglioside GM2 activatortarget
MifamurtideToll-like receptor 4target
MifamurtideNucleotide-binding oligomerization domain-containing protein 2target
1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamineRhodopsintarget
Glycerol 2-phosphateTriosephosphate isomerasetarget
L-DilinoleoyllecithinPhosphatidylcholine transfer proteintarget
sn-glycero-3-phosphoethanolamineAnnexin A5target
Cadaverine2-C-methyl-D-erythritol 4-phosphate cytidylyltransferasetarget
Erythritol5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferasetarget