Sugar Alcohols

Polyhydric alcohols having no more than one hydroxy group attached to each carbon atom. They are formed by the reduction of the carbonyl group of a sugar to a hydroxyl group.(From Dorland, 28th ed)
DrugDrug NameDrug Description
DB00271DiatrizoateAn injected contrast agent used in radiology.
DB00742MannitolA sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, and to measure glomerular filtration rate.
DB00743Gadobenic acidA gadolinium compound used as a contrast agent in MRIs.
DB00883Isosorbide dinitrateA vasodilator used to treat angina in coronary artery disease.
DB01020Isosorbide mononitrateA nitrate used to prevent and treat angina and to treat angina caused by coronary artery disease.
DB01613Erythrityl tetranitrateFor the prevention of angina.
DB01638SorbitolA product that can be used as a laxative to relieve constipation, and also as a urologic irrigating fluid. May also be used as a pharmaceutical sweetener.
DB01692DithioerythritolA compound that, along with its isomer, Cleland's reagent (dithiothreitol), is used for the protection of sulfhydryl groups against oxidation to disulfides and for the reduction of disulfides to sulfhydryl...
DB018402-Deoxy-D-Glucitol 6-(E)-VinylhomophosphonateNot Available
DB01863Inositol 1,3,4,5-TetrakisphosphateNot Available
DB021722,5-Dideoxy-2,5-Imino-D-GlucitolNot Available
DB02261Platelet Activating FactorNot Available
DB02492GhavamiolNot Available
DB02942Inositol 1,3-BisphosphateNot Available
DB03864MonothioglycerolNot Available
DB04878VogliboseFor the treatment of diabetes. It is specifically used for lowering post-prandial blood glucose levels thereby reducing the risk of macrovascular complications.
DB08909Glycerol phenylbutyrateA nitrogen-binding agent used to manage patients with urea cycle disorders who cannot be sufficiently managed amino acid supplementation and/or dietary restrictions.
DB09132Gadoteric acidA diagnostic contrast agent used with magnetic resonance imaging to provide contrast enhancement for intracranial and spinal lesions with abnormal blood brain barrier or abnormal vascularity, and for whole body imaging.
DB09133Iothalamic acidA diagnostic contrast agent used in various medical imaging procedures, such as angiography, arthrography, and computed tomographic scans.
DB09401IsosorbideA vasodilator used for the prevention and treatment of angina pectoris due to coronary artery disease.
DB09462GlycerinIt is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.
DB11195XylitolAn ingredient added to dental products to remove bacteria.
DB12214LuseogliflozinLuseogliflozin has been used in trials studying the treatment of Diabetes Melltius, Type 2.
DB12873DianhydrogalactitolDianhydrogalactitol has been used in trials studying the treatment of GBM, Glioma, Glioblastoma, Brain Cancer, and Glioblastoma Multiforme.
DB12916MitolactolMitolactol has been used in trials studying the treatment of Brain and Central Nervous System Tumors.
DB12969MethylinositolMethylinositol has been used in trials studying the treatment of Dementia and Alzheimer's Disease.
DB13178InositolAn ingredient found in a variety of nutritional products.
DB13444Ioxitalamic acidA contrast agent used for CT scans of the abdomen and pelvis.
DB13543MitobronitolNot Annotated
DB13732Meglumine antimoniateNot Annotated
DB14557EthylhexylglycerinAn emollient solvent with antimicrobial activity.
DB14704RibitolNot Annotated
DB03106scyllo-inositolAn isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been...
DB034011D-myo-inositol 1,4,5-trisphosphateIntracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the...
DB036462,3-di-O-phytanyl-sn-glycerolNot Available
DB03956Inositol 2,4,5-trisphosphateNot Available
DB00144Phosphatidyl serineA nutrient used in some supplement products.
DB03438LysophosphatidylglycerolNot Available
DB04143Indole-3-Glycerol PhosphateNot Available
DB04327PhosphatidylethanolamineNot Available
DB04660Choline alfoscerateA component of phosphatidylcholines (lecithins), in which the two hydroxy groups of glycerol are esterified with fatty acids. (From Stedman, 26th ed) It counteracts the effects of urea on enzymes...
DB04897LucinactantIntended for the prevention of respiratory distress syndrome (RDS) in premature infants at high risk for RDS.
DB05456ETC-588Investigated for use/treatment in atherosclerosis, coronary artery disease, and vascular diseases.
DB09114Colfosceril palmitateA pulmonary surfactant used for the treatment of Respiratory Distress Syndrome (RDS) in premature infants.
DB09561Sodium glycerophosphateA medication used to treat hypophosphatemia.
DB11283DL-dimyristoylphosphatidylcholineDL-dimyristoylphosphatidylcholine is not an active pharmaceutical agent and has no indication.
DB11284DL-dimyristoylphosphatidylglycerolDL-dimyristoylphosphatidylglycerol is not an considered an active pharmacological ingredient in pharmaceutical preparations and so has no official indications.
DB13615MifamurtideA muramyl dipeptide derivative used to treat high grade, resectable, non-metastatic osteosarcoma after surgical resection.
DB140991,2-DistearoyllecithinNot Annotated
DB15259VB-201VB-201 is under investigation in clinical trial NCT01001468 (Study to Assess VB-201 in Patients With Psoriasis).
DB13755Iocarmic acidNot Annotated
DB017281,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamineNot Available
DB01779Glycerol 2-phosphateNot Available
DrugDrug NameTargetType
DB00742MannitolP-glycoprotein 1transporter
DB00742MannitolMannitol dehydrogenaseenzyme
DB00743Gadobenic acidSerum albumincarrier
DB00883Isosorbide dinitrateAtrial natriuretic peptide receptor 1target
DB00883Isosorbide dinitrateCytochrome P450 2E1enzyme
DB01020Isosorbide mononitrateGuanylate cyclase soluble subunit alpha-2target
DB01020Isosorbide mononitrateGlutathione S-transferase Mu 1enzyme
DB01020Isosorbide mononitrateXanthine dehydrogenase/oxidaseenzyme
DB01020Isosorbide mononitrateAlcohol dehydrogenase class-3enzyme
DB01613Erythrityl tetranitrateAtrial natriuretic peptide receptor 1target
DB01613Erythrityl tetranitrateAtrial natriuretic peptide receptor 2target
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolXylose isomerasetarget
DB01638SorbitolMalate synthase Gtarget
DB01692DithioerythritolListeriolysin regulatory proteintarget
DB01692Dithioerythritol6,7-dimethyl-8-ribityllumazine synthasetarget
DB01692DithioerythritolThymidine kinase, cytosolictarget
DB018402-Deoxy-D-Glucitol 6-(E)-VinylhomophosphonateInositol-3-phosphate synthase 1target
DB01863Inositol 1,3,4,5-TetrakisphosphateRAC-alpha serine/threonine-protein kinasetarget
DB01863Inositol 1,3,4,5-TetrakisphosphatePleckstrin homology domain-containing family A member 4target
DB01863Inositol 1,3,4,5-TetrakisphosphateTyrosine-protein kinase BTKtarget
DB01863Inositol 1,3,4,5-TetrakisphosphateDual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositidetarget
DB01863Inositol 1,3,4,5-TetrakisphosphateInositol-trisphosphate 3-kinase Atarget
DB01863Inositol 1,3,4,5-TetrakisphosphateCytohesin-2target
DB01863Inositol 1,3,4,5-TetrakisphosphateCytohesin-3target
DB01863Inositol 1,3,4,5-Tetrakisphosphate3-phosphoinositide-dependent protein kinase 1target
DB021722,5-Dideoxy-2,5-Imino-D-GlucitolXylose isomerasetarget
DB02261Platelet Activating FactorGanglioside GM2 activatortarget
DB02261Platelet Activating FactorP-glycoprotein 1transporter
DB02261Platelet Activating FactorPlatelet-activating factor receptortarget
DB02492GhavamiolAlpha-mannosidase 2target
DB02942Inositol 1,3-BisphosphateEarly endosome antigen 1target
DB03864MonothioglycerolProlyl endopeptidasetarget
DB04878VogliboseMaltase-glucoamylase, intestinaltarget
DB08909Glycerol phenylbutyratePancreatic triacylglycerol lipaseenzyme
DB08909Glycerol phenylbutyrateCytochrome P450 3A4enzyme
DB08909Glycerol phenylbutyrateCytochrome P450 2D6enzyme
DB09401IsosorbideApoptosis regulator Bcl-2target
DB09401IsosorbideBcl-2-like protein 1target
DB09401IsosorbideInduced myeloid leukemia cell differentiation protein Mcl-1target
DB09462GlycerinHematopoietic prostaglandin D synthasetarget
DB09462GlycerinEndoglucanase Gtarget
DB09462GlycerinGlutathione S-transferase Ptarget
DB09462GlycerinGroup IIE secretory phospholipase A2target
DB09462GlycerinInositol-3-phosphate synthase 1target
DB09462GlycerinC4-dicarboxylate transport transcriptional regulatory protein DctDtarget
DB09462GlycerinAlcohol dehydrogenase 1Btarget
DB09462GlycerinInositol 1,4,5-trisphosphate receptor type 1target
DB09462GlycerinGlycodelintarget
DB09462GlycerinAlpha-N-acetylgalactosaminidasetarget
DB09462GlycerinCytochrome c4target
DB09462GlycerinBacterioferritintarget
DB09462GlycerinTGF-beta receptor type-2target
DB09462GlycerinArgininosuccinate synthasetarget
DB09462GlycerinEnolasetarget
DB09462GlycerinADP-ribosylation factor 1target
DB09462GlycerinMultidrug resistance protein MexAtarget
DB09462GlycerinBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1target
DB09462GlycerinHistidinol dehydrogenasetarget
DB09462GlycerinDNA mismatch repair protein MutLtarget
DB09462GlycerinGlycerol uptake facilitator proteintarget
DB09462GlycerinRibonucleoside-diphosphate reductase 1 subunit betatarget
DB09462GlycerinA/G-specific adenine glycosylasetarget
DB09462GlycerintRNA (cytosine(38)-C(5))-methyltransferasetarget
DB09462GlycerinCytochrome P450 2E1enzyme
DB09462GlycerinRetinal dehydrogenase 1enzyme
DB09462GlycerinPeroxisome proliferator-activated receptor deltatarget
DB11195XylitolXylose isomerasetarget
DB11195XylitolXylose isomerasetarget
DB11195XylitolXylose isomerasetarget
DB11195XylitolXylose isomerasetarget
DB11195XylitolHyaluronate lyasetarget
DB13178InositolSodium/myo-inositol cotransportertransporter
DB03106scyllo-inositolGlucosylceramidasetarget
DB03106scyllo-inositol1-phosphatidylinositol phosphodiesterasetarget
DB03106scyllo-inositolCDP-diacylglycerol--inositol 3-phosphatidyltransferasetarget
DB03106scyllo-inositol1-phosphatidylinositol phosphodiesterasetarget
DB034011D-myo-inositol 1,4,5-trisphosphateCytohesin-2target
DB034011D-myo-inositol 1,4,5-trisphosphateEpsin-1target
DB034011D-myo-inositol 1,4,5-trisphosphate1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1target
DB034011D-myo-inositol 1,4,5-trisphosphateRadixintarget
DB034011D-myo-inositol 1,4,5-trisphosphateSpectrin beta chain, non-erythrocytic 1target
DB034011D-myo-inositol 1,4,5-trisphosphateInositol 1,4,5-trisphosphate receptor type 1target
DB034011D-myo-inositol 1,4,5-trisphosphateInositol-trisphosphate 3-kinase Atarget
DB03956Inositol 2,4,5-trisphosphate1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1target
DB00144Phosphatidyl serinePhosphatidylserine decarboxylase proenzymetarget
DB00144Phosphatidyl serineScavenger receptor class B member 1target
DB00144Phosphatidyl serineProtein kinase C alpha typetarget
DB00144Phosphatidyl serinePhosphatidylserine synthase 1target
DB00144Phosphatidyl serineDiacylglycerol kinase gammatarget
DB00144Phosphatidyl serineDiacylglycerol kinase deltatarget
DB00144Phosphatidyl serinePhosphatidylserine synthase 2target
DB00144Phosphatidyl serineSphingomyelin phosphodiesterase 4target
DB00144Phosphatidyl serineSphingomyelin phosphodiesterase 3target
DB00144Phosphatidyl serineProbable phospholipid-transporting ATPase IAtarget
DB04143Indole-3-Glycerol PhosphateTryptophan synthase alpha chaintarget
DB04143Indole-3-Glycerol PhosphateTryptophan synthase beta chaintarget
DB04327PhosphatidylethanolamineEndothelial protein C receptortarget
DB04327PhosphatidylethanolamineBacteriorhodopsintarget
DB04327PhosphatidylethanolaminePhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTENtarget
DB04660Choline alfoscerateGanglioside GM2 activatortarget
DB13615MifamurtideToll-like receptor 4target
DB13615MifamurtideNucleotide-binding oligomerization domain-containing protein 2target
DB017281,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamineRhodopsintarget
DB01779Glycerol 2-phosphateTriosephosphate isomerasetarget